Click here to switch to the map view.

The map label for this gene is 21226188

Identifier: 21226188

GI number: 21226188

Start: 111384

End: 111917

Strand: Reverse

Name: 21226188

Synonym: MM_0086

Alternate gene names: NA

Gene position: 111917-111384 (Counterclockwise)

Preceding gene: 21226189

Following gene: 21226187

Centisome position: 2.73

GC content: 49.25

Gene sequence:

>534_bases
ATGAAGAGAATTGTATTACTGCGCCTGGGGCACCGCCCTGAGAGGGACAAGAGGATTACCACACACGTTGGCTTAACTGC
CAGGATGCTTGGAGCTGAAGGCATGCTTCTTGCTTCTGATGACTCCGGGATTGTGCAGAGCCTTGAAGATGTGGTCAGGC
GCTGGGGTGGAAACTTTTACATTAAAAATAATGTCAGCTTTAAACAGGAAATCAGAAACTGGAAAGAAGGAGGAGGTAAA
GTCTGCCACCTTTCCATGTACGGAGTCAACCTTCCGGATCTTGCTGACGAGCTTAAAAAGTGCGACAAATTAATGATTGT
TGTGGGTGCGGAAAAAGTCCCTCCCGAAATTTACCAGCTCGCTGACTGGAATGTGGCCGTGGGAAGCCAGCCTCATTCCG
AAGTTGCGGCAGTTGCAATTACAATGGACAGAATCGCCGAGGGTGAGCCTCTTGAAAAAGAGTTTCCGGGCGCTGAACTG
ACAATTGTCCCTGCCGAAAGGGGCAAACATGTAATCGAAAATGCCGGGGAATGA

Upstream 100 bases:

>100_bases
TTCCAGTAATATTTCTGTAAGAACAATTTTCTCTTTTTTTCTTTTTTTCAATGAAAGCTCAGTGAAACCCTTTAATACCT
TGTCAGGGTTTTAGCCGGAC

Downstream 100 bases:

>100_bases
AACGGGTTCAGCAGGTCATGACAGCAGCTTCTCGATTTTTATCTTTTATATTTTTGACTCTATGTTTTGTTACGAATATT
TAGAAAAGTGTTAAATATAA

Product: tRNA 2'-O-methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MKRIVLLRLGHRPERDKRITTHVGLTARMLGAEGMLLASDDSGIVQSLEDVVRRWGGNFYIKNNVSFKQEIRNWKEGGGK
VCHLSMYGVNLPDLADELKKCDKLMIVVGAEKVPPEIYQLADWNVAVGSQPHSEVAAVAITMDRIAEGEPLEKEFPGAEL
TIVPAERGKHVIENAGE

Sequences:

>Translated_177_residues
MKRIVLLRLGHRPERDKRITTHVGLTARMLGAEGMLLASDDSGIVQSLEDVVRRWGGNFYIKNNVSFKQEIRNWKEGGGK
VCHLSMYGVNLPDLADELKKCDKLMIVVGAEKVPPEIYQLADWNVAVGSQPHSEVAAVAITMDRIAEGEPLEKEFPGAEL
TIVPAERGKHVIENAGE
>Mature_177_residues
MKRIVLLRLGHRPERDKRITTHVGLTARMLGAEGMLLASDDSGIVQSLEDVVRRWGGNFYIKNNVSFKQEIRNWKEGGGK
VCHLSMYGVNLPDLADELKKCDKLMIVVGAEKVPPEIYQLADWNVAVGSQPHSEVAAVAITMDRIAEGEPLEKEFPGAEL
TIVPAERGKHVIENAGE

Specific function: Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs [H]

COG id: COG1303

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aTrm56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002845
- ProDom:   PD016584 [H]

Pfam domain/function: PF01994 DUF127 [H]

EC number: NA

Molecular weight: Translated: 19583; Mature: 19583

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRIVLLRLGHRPERDKRITTHVGLTARMLGAEGMLLASDDSGIVQSLEDVVRRWGGNFY
CCEEEEEEECCCCCCCCEEEEECCCEEEEECCCCEEEECCCCHHHHHHHHHHHHCCCCEE
IKNNVSFKQEIRNWKEGGGKVCHLSMYGVNLPDLADELKKCDKLMIVVGAEKVPPEIYQL
EECCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCEEEEEECCCCCCHHHHHH
ADWNVAVGSQPHSEVAAVAITMDRIAEGEPLEKEFPGAELTIVPAERGKHVIENAGE
CCCCEEECCCCCHHHEEEEEEHHHHCCCCCCHHHCCCCEEEEEECCCCCHHHCCCCC
>Mature Secondary Structure
MKRIVLLRLGHRPERDKRITTHVGLTARMLGAEGMLLASDDSGIVQSLEDVVRRWGGNFY
CCEEEEEEECCCCCCCCEEEEECCCEEEEECCCCEEEECCCCHHHHHHHHHHHHCCCCEE
IKNNVSFKQEIRNWKEGGGKVCHLSMYGVNLPDLADELKKCDKLMIVVGAEKVPPEIYQL
EECCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCEEEEEECCCCCCHHHHHH
ADWNVAVGSQPHSEVAAVAITMDRIAEGEPLEKEFPGAELTIVPAERGKHVIENAGE
CCCCEEECCCCCHHHEEEEEEHHHHCCCCCCHHHCCCCEEEEEECCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]