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The map label for this gene is apgM

Identifier: 161485676

GI number: 161485676

Start: 1700863

End: 1702056

Strand: Direct

Name: apgM

Synonym: MM_1418

Alternate gene names: 161485676

Gene position: 1700863-1702056 (Clockwise)

Preceding gene: 21227517

Following gene: 21227521

Centisome position: 41.52

GC content: 46.57

Gene sequence:

>1194_bases
ATGAAATATGCCATACTTATAGGAGACGGAATGGCGGATTACCCTATAGAGAAACTGGGTAACAGGACTATTCTACAGGC
AGCCCGAACACCTGCTATGGATTCCATTGCAGCGCGCGGGAGAGCCGGGCTTGCAAAGACCGTACCTGATAGTTTTCCTC
CAGGAAGCGACGTTGCAAATATGTCAATTCTGGGATACGACCCGGCAACCTATTACTCAGGAAGGGCTCCTCTGGAAGCT
GCGAGTATGGGAGTAGCTCTTGCAGCGGACGATGTGGCTTTCAGGTGCAATCTTATTACCACAGAGCACGGGATGATAAA
AGACTACAGTGCAGGGCATATCAGCAGTGATGAAGCAGAGATTTTGATTGATACTCTTGATTACGAACTCAGTACAGAGA
ATATCAGGTTTTATCCGGGAATAAGTTACAGGCACCTTATCGTTGCCGGAAATAACCTGGGGGCAGAAACGGAATGCACA
CCTCCGCACGATATCACAGGAGAGAAAATAGATAAATATCTGCCCAGAGGAAAAGACGGGGAGTTTTTCTCAGAGCTTAT
TGAAGCTTCCAAGGTTGTTCTGGAACTGCATCCCGTTAACCTTAAACGAGTGGAGGAAGGAAAAAACCCTGCAAACTCTA
TCTGGGTCTGGGGGCAGGGCTACGCCCCGAAGTTCACGGCTTTTATGAAACTTTATGGGAAAAAAGGAGCTGTCATTTCC
GCAGTGGATTTGCTTAAGGGAATCGGGATTTATGCCGGGCTGGATGTAATTGAAGTCCACGGAGCAACCGGTTACCTGGA
TACCAATTATGAGGGGAAGGTCAGAGCAGCTATTGAAGCATTGAAAACCAGAGATCTTGTTTTCGTGCATGTCGAGGCTC
CTGATGAGGCAGGGCACGAAGGCAGCATTGAGAAAAAGTTGAAGGCAGTTGAGGATTTTGACAGCCGCATAGTTGCCCCT
ATCCTTGAATACGCAGAAAACTCAGATGAGCCTTTTACAATCCTTGTACTTCCTGACCATCCTACCCCTATATCAGTAAA
GACCCATACACGAGACCCTATTCCGTTTGCTATCTACAGAACTGATAAACCAGAAACGGACAATGTGGAAGCCTTTGATG
AGGAATCAGTTAAAAATGGCTCTATGGGACTCGTAAAAGCTTCAGACCTCATAGGAATTCTTATAAAGAGCTAA

Upstream 100 bases:

>100_bases
CTGGCAGGTGCCAAAAAAATATTATTCAGGTATCTGGTAGAAAGTGATATATTTTATCCGCAAGAAGAAATGGCTAAAGC
AGTTGGAAAAAGGTGAAGCA

Downstream 100 bases:

>100_bases
ATTTTTTCAGGCTCTTTATAAGTTTTTCTGTTACCAGATTTTTATAATATTCTATGTTATCAGAATCTTTATGTTCTTTG
CAAGGTTCTCTCTTACCAGG

Product: cofactor-independent phosphoglycerate mutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; aPGAM

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKYAILIGDGMADYPIEKLGNRTILQAARTPAMDSIAARGRAGLAKTVPDSFPPGSDVANMSILGYDPATYYSGRAPLEA
ASMGVALAADDVAFRCNLITTEHGMIKDYSAGHISSDEAEILIDTLDYELSTENIRFYPGISYRHLIVAGNNLGAETECT
PPHDITGEKIDKYLPRGKDGEFFSELIEASKVVLELHPVNLKRVEEGKNPANSIWVWGQGYAPKFTAFMKLYGKKGAVIS
AVDLLKGIGIYAGLDVIEVHGATGYLDTNYEGKVRAAIEALKTRDLVFVHVEAPDEAGHEGSIEKKLKAVEDFDSRIVAP
ILEYAENSDEPFTILVLPDHPTPISVKTHTRDPIPFAIYRTDKPETDNVEAFDEESVKNGSMGLVKASDLIGILIKS

Sequences:

>Translated_397_residues
MKYAILIGDGMADYPIEKLGNRTILQAARTPAMDSIAARGRAGLAKTVPDSFPPGSDVANMSILGYDPATYYSGRAPLEA
ASMGVALAADDVAFRCNLITTEHGMIKDYSAGHISSDEAEILIDTLDYELSTENIRFYPGISYRHLIVAGNNLGAETECT
PPHDITGEKIDKYLPRGKDGEFFSELIEASKVVLELHPVNLKRVEEGKNPANSIWVWGQGYAPKFTAFMKLYGKKGAVIS
AVDLLKGIGIYAGLDVIEVHGATGYLDTNYEGKVRAAIEALKTRDLVFVHVEAPDEAGHEGSIEKKLKAVEDFDSRIVAP
ILEYAENSDEPFTILVLPDHPTPISVKTHTRDPIPFAIYRTDKPETDNVEAFDEESVKNGSMGLVKASDLIGILIKS
>Mature_397_residues
MKYAILIGDGMADYPIEKLGNRTILQAARTPAMDSIAARGRAGLAKTVPDSFPPGSDVANMSILGYDPATYYSGRAPLEA
ASMGVALAADDVAFRCNLITTEHGMIKDYSAGHISSDEAEILIDTLDYELSTENIRFYPGISYRHLIVAGNNLGAETECT
PPHDITGEKIDKYLPRGKDGEFFSELIEASKVVLELHPVNLKRVEEGKNPANSIWVWGQGYAPKFTAFMKLYGKKGAVIS
AVDLLKGIGIYAGLDVIEVHGATGYLDTNYEGKVRAAIEALKTRDLVFVHVEAPDEAGHEGSIEKKLKAVEDFDSRIVAP
ILEYAENSDEPFTILVLPDHPTPISVKTHTRDPIPFAIYRTDKPETDNVEAFDEESVKNGSMGLVKASDLIGILIKS

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG3635

COG function: function code G; Predicted phosphoglycerate mutase, AP superfamily

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APGM_METMA (Q8PX04)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_633442.2
- ProteinModelPortal:   Q8PX04
- GeneID:   1479760
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_1418
- NMPDR:   fig|192952.1.peg.1418
- HOGENOM:   HBG463247
- OMA:   DYSAGHI
- ProtClustDB:   PRK04200
- BioCyc:   MMAZ192952:MM1418-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0006096
- HAMAP:   MF_01402_A
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR004456
- InterPro:   IPR013371
- InterPro:   IPR006124
- Gene3D:   G3DSA:3.40.720.10
- PIRSF:   PIRSF006392
- TIGRFAMs:   TIGR00306
- TIGRFAMs:   TIGR02535

Pfam domain/function: PF01676 Metalloenzyme; PF10143 PhosphMutase; SSF53649 Alkaline_phosphatase_core

EC number: =5.4.2.1

Molecular weight: Translated: 43175; Mature: 43175

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAILIGDGMADYPIEKLGNRTILQAARTPAMDSIAARGRAGLAKTVPDSFPPGSDVAN
CEEEEEEECCCCCCCHHHHCCEEEEHHHCCCCHHHHHHCCCCCCHHCCCCCCCCCCCCCC
MSILGYDPATYYSGRAPLEAASMGVALAADDVAFRCNLITTEHGMIKDYSAGHISSDEAE
EEEEECCCHHCCCCCCCCHHHHCCEEEEECCEEEEEEEEECCCCCEECCCCCCCCCCCCE
ILIDTLDYELSTENIRFYPGISYRHLIVAGNNLGAETECTPPHDITGEKIDKYLPRGKDG
EEEEEECCEECCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCH
EFFSELIEASKVVLELHPVNLKRVEEGKNPANSIWVWGQGYAPKFTAFMKLYGKKGAVIS
HHHHHHHHHCEEEEEEECCCHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEH
AVDLLKGIGIYAGLDVIEVHGATGYLDTNYEGKVRAAIEALKTRDLVFVHVEAPDEAGHE
HHHHHHHCCHHCCCEEEEECCCCCEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCC
GSIEKKLKAVEDFDSRIVAPILEYAENSDEPFTILVLPDHPTPISVKTHTRDPIPFAIYR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCCCCCEEEEE
TDKPETDNVEAFDEESVKNGSMGLVKASDLIGILIKS
CCCCCCCCCCCCCHHHCCCCCEEEEECCCEEEEEEEC
>Mature Secondary Structure
MKYAILIGDGMADYPIEKLGNRTILQAARTPAMDSIAARGRAGLAKTVPDSFPPGSDVAN
CEEEEEEECCCCCCCHHHHCCEEEEHHHCCCCHHHHHHCCCCCCHHCCCCCCCCCCCCCC
MSILGYDPATYYSGRAPLEAASMGVALAADDVAFRCNLITTEHGMIKDYSAGHISSDEAE
EEEEECCCHHCCCCCCCCHHHHCCEEEEECCEEEEEEEEECCCCCEECCCCCCCCCCCCE
ILIDTLDYELSTENIRFYPGISYRHLIVAGNNLGAETECTPPHDITGEKIDKYLPRGKDG
EEEEEECCEECCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCH
EFFSELIEASKVVLELHPVNLKRVEEGKNPANSIWVWGQGYAPKFTAFMKLYGKKGAVIS
HHHHHHHHHCEEEEEEECCCHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEH
AVDLLKGIGIYAGLDVIEVHGATGYLDTNYEGKVRAAIEALKTRDLVFVHVEAPDEAGHE
HHHHHHHCCHHCCCEEEEECCCCCEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCC
GSIEKKLKAVEDFDSRIVAPILEYAENSDEPFTILVLPDHPTPISVKTHTRDPIPFAIYR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECCCCCCCEEEEE
TDKPETDNVEAFDEESVKNGSMGLVKASDLIGILIKS
CCCCCCCCCCCCCHHHCCCCCEEEEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12125824