BacMap

Definition	Thermoanaerobacter tengcongensis MB4, complete genome.
Accession	NC_003869
Length	2,689,445

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The map label for this gene is FabG6 [H]

Identifier: 20809051

GI number: 20809051

Start: 2606195

End: 2606983

Strand: Direct

Name: FabG6 [H]

Synonym: TTE2709

Alternate gene names: 20809051

Gene position: 2606195-2606983 (Clockwise)

Preceding gene: 20809050

Following gene: 20809058

Centisome position: 96.9

GC content: 36.63

Gene sequence:

>789_bases
ATGGATCTTGGTCTTAAAGATAAGGTAGCATTTGTAATGGCTGGAAGTAAAGGCCTTGGAAAAGCAGTCGCTTTAGAACT
TGCAAAAGAGGGAGCCAATGTTTCTATTATTTCAAGAAGCAGAGAAAATTTAAAAAAGGCCCAAGAAGAAATTAAATCAA
TAACAGGAAAAGAAGTACTTATAGTTGAAGGAGATGTAGCTCGCAAAGAAGATATTGAAAAGGCTGTAAAAGAAACAGTA
AGTAAGTTCGGCACAATCCACATCCTCTTTGCAAATGCAGGAGGTCCTCCTGCTGGTGGGTTTTTTGATGTAAAGCCTGA
AGATTACTTAAAAGCAGTTGAATTAAATTTAATGAGCACAATATATGCAGTATATGCAGTAAAGGATTATATGATAAATC
AAAAATGGGGAAGGATAATAGCTTCAACATCGATATCAGTAAAGCAGCCCCTTGATAATTTAATCCTTTCAAATGTATCA
AGAATGGGGGTAGTCGCTTTTATAAAGTCTATATCAAATGCATTAGCACCATTTGGAATTACTGCAAATGCCGTAGCCCC
CGGCTACACAATGACTGAAAGAATAGAAAATCTCCTTAAAGCAAGAGTTGAAAAAGAAGGCATAACCTTTGAAGAAGCGC
AAAAATCAATGATTACAGACATCCCCATGAAGCGCTTGGGTACTGTTGAAGAATTTGCATCAACTGTTTTGTTTTTAGCA
TCAGAAAAAGCCTCCTACATAACAGGCATAGTCGTGCCAATTGATGGAGGTTTTATAAAAGGAGTGTAA

Upstream 100 bases:

>100_bases
CAGTATCTTGACACTATCTTCTGGGTGCATAAACTTTAAAACTTTTAAAAAAAATGATAAAATATGTATTAAACAAATAT
TTCTATAAGGAGAGATTTAT

Downstream 100 bases:

>100_bases
AAGCTGAGCTACAAGCTTAGCTTTTACACTCCTTTAAAACCTTTTACACGCTATCTAACTTCATCCCTCACTATTTTCCC
ATCCCTTATATTAATTTGCC

Product: dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MDLGLKDKVAFVMAGSKGLGKAVALELAKEGANVSIISRSRENLKKAQEEIKSITGKEVLIVEGDVARKEDIEKAVKETV
SKFGTIHILFANAGGPPAGGFFDVKPEDYLKAVELNLMSTIYAVYAVKDYMINQKWGRIIASTSISVKQPLDNLILSNVS
RMGVVAFIKSISNALAPFGITANAVAPGYTMTERIENLLKARVEKEGITFEEAQKSMITDIPMKRLGTVEEFASTVLFLA
SEKASYITGIVVPIDGGFIKGV

Sequences:

>Translated_262_residues
MDLGLKDKVAFVMAGSKGLGKAVALELAKEGANVSIISRSRENLKKAQEEIKSITGKEVLIVEGDVARKEDIEKAVKETV
SKFGTIHILFANAGGPPAGGFFDVKPEDYLKAVELNLMSTIYAVYAVKDYMINQKWGRIIASTSISVKQPLDNLILSNVS
RMGVVAFIKSISNALAPFGITANAVAPGYTMTERIENLLKARVEKEGITFEEAQKSMITDIPMKRLGTVEEFASTVLFLA
SEKASYITGIVVPIDGGFIKGV
>Mature_262_residues
MDLGLKDKVAFVMAGSKGLGKAVALELAKEGANVSIISRSRENLKKAQEEIKSITGKEVLIVEGDVARKEDIEKAVKETV
SKFGTIHILFANAGGPPAGGFFDVKPEDYLKAVELNLMSTIYAVYAVKDYMINQKWGRIIASTSISVKQPLDNLILSNVS
RMGVVAFIKSISNALAPFGITANAVAPGYTMTERIENLLKARVEKEGITFEEAQKSMITDIPMKRLGTVEEFASTVLFLA
SEKASYITGIVVPIDGGFIKGV

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=31.9066147859922, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=1e-25,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=29.3650793650794, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI5031737, Length=253, Percent_Identity=28.0632411067194, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4503301, Length=254, Percent_Identity=31.496062992126, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI126723750, Length=261, Percent_Identity=29.1187739463602, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI10190704, Length=266, Percent_Identity=27.0676691729323, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI33667109, Length=270, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI66933014, Length=236, Percent_Identity=28.3898305084746, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI31542939, Length=220, Percent_Identity=29.0909090909091, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI15277342, Length=268, Percent_Identity=28.3582089552239, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI7706318, Length=207, Percent_Identity=28.0193236714976, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4503817, Length=194, Percent_Identity=25.7731958762887, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI7705925, Length=259, Percent_Identity=24.3243243243243, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=30.6451612903226, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI59889578, Length=228, Percent_Identity=24.5614035087719, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=31.0077519379845, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI87082160, Length=260, Percent_Identity=28.4615384615385, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=30.46875, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787905, Length=261, Percent_Identity=25.2873563218391, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=27.906976744186, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=27.9527559055118, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789378, Length=261, Percent_Identity=26.8199233716475, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=25.1937984496124, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=26.7716535433071, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI2367175, Length=262, Percent_Identity=27.0992366412214, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=25.1968503937008, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=32.8063241106719, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=33.7037037037037, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=31.7460317460317, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=32.2709163346614, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=27.843137254902, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=29.6442687747036, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17560220, Length=259, Percent_Identity=30.5019305019305, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=30.1526717557252, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=28.3524904214559, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=28.5171102661597, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=30.5970149253731, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25147288, Length=260, Percent_Identity=29.2307692307692, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17561272, Length=259, Percent_Identity=31.2741312741313, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=29.9625468164794, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=30.1526717557252, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=265, Percent_Identity=29.0566037735849, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=29.6577946768061, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=29.7397769516729, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=261, Percent_Identity=27.5862068965517, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=259, Percent_Identity=28.1853281853282, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=29.1044776119403, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=256, Percent_Identity=26.5625, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=28.2442748091603, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=270, Percent_Identity=25.5555555555556, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=27.2373540856031, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=26.6409266409266, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=256, Percent_Identity=26.5625, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=256, Percent_Identity=26.5625, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=26.9961977186312, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=25.2873563218391, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=26.7441860465116, Blast_Score=95, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6322861, Length=216, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=34.1085271317829, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=30.4, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=33.7209302325581, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=30.2325581395349, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=29.9610894941634, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24639444, Length=264, Percent_Identity=29.9242424242424, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24644337, Length=232, Percent_Identity=29.3103448275862, Blast_Score=91, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 28263; Mature: 28263

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLKDKVAFVMAGSKGLGKAVALELAKEGANVSIISRSRENLKKAQEEIKSITGKEVL
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEE
IVEGDVARKEDIEKAVKETVSKFGTIHILFANAGGPPAGGFFDVKPEDYLKAVELNLMST
EEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEECCCHHHHHHHHHHHHHHH
IYAVYAVKDYMINQKWGRIIASTSISVKQPLDNLILSNVSRMGVVAFIKSISNALAPFGI
HHHHHHHHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TANAVAPGYTMTERIENLLKARVEKEGITFEEAQKSMITDIPMKRLGTVEEFASTVLFLA
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
SEKASYITGIVVPIDGGFIKGV
CCCCCEEEEEEEEECCCEECCC
>Mature Secondary Structure
MDLGLKDKVAFVMAGSKGLGKAVALELAKEGANVSIISRSRENLKKAQEEIKSITGKEVL
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEE
IVEGDVARKEDIEKAVKETVSKFGTIHILFANAGGPPAGGFFDVKPEDYLKAVELNLMST
EEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEECCCHHHHHHHHHHHHHHH
IYAVYAVKDYMINQKWGRIIASTSISVKQPLDNLILSNVSRMGVVAFIKSISNALAPFGI
HHHHHHHHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TANAVAPGYTMTERIENLLKARVEKEGITFEEAQKSMITDIPMKRLGTVEEFASTVLFLA
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
SEKASYITGIVVPIDGGFIKGV
CCCCCEEEEEEEEECCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]