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The map label for this gene is SplB [H]

Identifier: 20809021

GI number: 20809021

Start: 2573613

End: 2574617

Strand: Reverse

Name: SplB [H]

Synonym: TTE2677

Alternate gene names: 20809021

Gene position: 2574617-2573613 (Counterclockwise)

Preceding gene: 20809022

Following gene: 20809020

Centisome position: 95.73

GC content: 35.22

Gene sequence:

>1005_bases
TTGAAGAAGTTCTCTCACATTTACGTTGAAGAGGATGTAAAAAACCATCCTTTGACGATAAAAATATTGAATAAGTTTCC
TAAGAGCAAAATTGTATATATTAACAGATACAGTGAAGTTTTTAACAGGCCCAATCAAAATTATTTGGTTCAGAAAAAGG
GGCAGAACCTGATAATTGCTAAGAAAAGGCATGAGTTTGTGTATAAAGGGTCAGAACTTTGTGAAGATTTTGGAAATATA
CATTTTTTCCATACATCGAATATATACAATTGCGTCTATGAGTGTGAATACTGCTATCTGCAAGGGTTGTACCCTTCTGC
TCACTTGGTGATATTTGTAAATCTGGAAGATTATTTCAGAGAAATAGACAAGCTCATAGAAAGAAAAAAGATATATTTGA
GCATTTCCTATGAGACGGATTTGCTGGCATTAGAATATTTAACGGGTTTTACCAGAGAGTGGATTGAATACGCTTCTTCT
AGGGACCTCCTTTTGGAGATTAGGACGAAGAGTGCTAACTTTTCTGCTCTAGAAGATTTGGAAATTCCACCAAATGTCAT
TTTTGCTTGGACTTTATTGCCCCAACCTGTAATTGATAGATATGAGAAATTTACTCCTTCTCTTGAGATGAGATTAAAAA
GCATCAAAAAAGCCATTTCAAGAGGGCTTAGAATCAGAATATCCATTGAGCCTGTGATGTACTTGGAAAACTTTGAAGAA
GTGTACAGCCAATTTGTTAAAGAAGTTTTCTCCTGCATTCCTGAAAAGAGCGTAAGAGATGTGAATATTGGCGCTTTTAG
GCTGCCAAAAGAACAGGCAAAAAGGATAGAAAAGTTAAACGAGGCCTCCCTTATATTTTGCTATGACACTGTTGTGAAAG
ATGAGGTTTTTACGTACAGGAACGCTTCAGATTATGAGAATTTTGTTGCAGAAGAAGTAAAGAAATATGTCCCTTCAGAG
AAAGTGTATGTCTTCAATAAAAAAGAAAAAAGCTCCCTTTTTTGA

Upstream 100 bases:

>100_bases
GCTTGCCTTCACTATAAAGTGCGGGAAAATAAAGGCGTTGATTTTTTAAAAGGTTTTTTTGGGATGGAGGTTACAAACAA
AAAAGAGAGGGAGAAGGCCT

Downstream 100 bases:

>100_bases
GGTTTTCCTTTACATCAATAAACTATGTACCTCCTTCGCTTTTTTCCATCTCTATTTCCTGCTTTTTATTATCTTTTAAG
AGGCACAAATACACTTTCTC

Product: DNA repair photolyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKKFSHIYVEEDVKNHPLTIKILNKFPKSKIVYINRYSEVFNRPNQNYLVQKKGQNLIIAKKRHEFVYKGSELCEDFGNI
HFFHTSNIYNCVYECEYCYLQGLYPSAHLVIFVNLEDYFREIDKLIERKKIYLSISYETDLLALEYLTGFTREWIEYASS
RDLLLEIRTKSANFSALEDLEIPPNVIFAWTLLPQPVIDRYEKFTPSLEMRLKSIKKAISRGLRIRISIEPVMYLENFEE
VYSQFVKEVFSCIPEKSVRDVNIGAFRLPKEQAKRIEKLNEASLIFCYDTVVKDEVFTYRNASDYENFVAEEVKKYVPSE
KVYVFNKKEKSSLF

Sequences:

>Translated_334_residues
MKKFSHIYVEEDVKNHPLTIKILNKFPKSKIVYINRYSEVFNRPNQNYLVQKKGQNLIIAKKRHEFVYKGSELCEDFGNI
HFFHTSNIYNCVYECEYCYLQGLYPSAHLVIFVNLEDYFREIDKLIERKKIYLSISYETDLLALEYLTGFTREWIEYASS
RDLLLEIRTKSANFSALEDLEIPPNVIFAWTLLPQPVIDRYEKFTPSLEMRLKSIKKAISRGLRIRISIEPVMYLENFEE
VYSQFVKEVFSCIPEKSVRDVNIGAFRLPKEQAKRIEKLNEASLIFCYDTVVKDEVFTYRNASDYENFVAEEVKKYVPSE
KVYVFNKKEKSSLF
>Mature_334_residues
MKKFSHIYVEEDVKNHPLTIKILNKFPKSKIVYINRYSEVFNRPNQNYLVQKKGQNLIIAKKRHEFVYKGSELCEDFGNI
HFFHTSNIYNCVYECEYCYLQGLYPSAHLVIFVNLEDYFREIDKLIERKKIYLSISYETDLLALEYLTGFTREWIEYASS
RDLLLEIRTKSANFSALEDLEIPPNVIFAWTLLPQPVIDRYEKFTPSLEMRLKSIKKAISRGLRIRISIEPVMYLENFEE
VYSQFVKEVFSCIPEKSVRDVNIGAFRLPKEQAKRIEKLNEASLIFCYDTVVKDEVFTYRNASDYENFVAEEVKKYVPSE
KVYVFNKKEKSSLF

Specific function: Involved in repair of UV radiation-induced DNA damage during spore germination. Can repair thymine dimer 5-thyminyl-5,6- dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines [H]

COG id: COG1533

COG function: function code L; DNA repair photolyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. SPL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR004594 [H]

Pfam domain/function: NA

EC number: =4.1.99.14 [H]

Molecular weight: Translated: 39667; Mature: 39667

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFSHIYVEEDVKNHPLTIKILNKFPKSKIVYINRYSEVFNRPNQNYLVQKKGQNLIIA
CCCCCEEEEECCCCCCCEEEEEECCCCCCEEEEEEEHHHHHCCCCCCEEEEECCCEEEEE
KKRHEFVYKGSELCEDFGNIHFFHTSNIYNCVYECEYCYLQGLYPSAHLVIFVNLEDYFR
ECCHHHHCCCHHHHHHHCCEEEEECCCCEEHHHHCCCCEEECCCCCCEEEEEEEHHHHHH
EIDKLIERKKIYLSISYETDLLALEYLTGFTREWIEYASSRDLLLEIRTKSANFSALEDL
HHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHCC
EIPPNVIFAWTLLPQPVIDRYEKFTPSLEMRLKSIKKAISRGLRIRISIEPVMYLENFEE
CCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHH
VYSQFVKEVFSCIPEKSVRDVNIGAFRLPKEQAKRIEKLNEASLIFCYDTVVKDEVFTYR
HHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCC
NASDYENFVAEEVKKYVPSEKVYVFNKKEKSSLF
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MKKFSHIYVEEDVKNHPLTIKILNKFPKSKIVYINRYSEVFNRPNQNYLVQKKGQNLIIA
CCCCCEEEEECCCCCCCEEEEEECCCCCCEEEEEEEHHHHHCCCCCCEEEEECCCEEEEE
KKRHEFVYKGSELCEDFGNIHFFHTSNIYNCVYECEYCYLQGLYPSAHLVIFVNLEDYFR
ECCHHHHCCCHHHHHHHCCEEEEECCCCEEHHHHCCCCEEECCCCCCEEEEEEEHHHHHH
EIDKLIERKKIYLSISYETDLLALEYLTGFTREWIEYASSRDLLLEIRTKSANFSALEDL
HHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHCC
EIPPNVIFAWTLLPQPVIDRYEKFTPSLEMRLKSIKKAISRGLRIRISIEPVMYLENFEE
CCCCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHH
VYSQFVKEVFSCIPEKSVRDVNIGAFRLPKEQAKRIEKLNEASLIFCYDTVVKDEVFTYR
HHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHCCCCCEEEEEHHHHHHHHHCCC
NASDYENFVAEEVKKYVPSEKVYVFNKKEKSSLF
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8449881; 9384377; 9353924 [H]