Click here to switch to the map view.

The map label for this gene is SurA2

Identifier: 20808913

GI number: 20808913

Start: 2451691

End: 2452611

Strand: Reverse

Name: SurA2

Synonym: TTE2564

Alternate gene names: 20808913

Gene position: 2452611-2451691 (Counterclockwise)

Preceding gene: 20808914

Following gene: 20808912

Centisome position: 91.19

GC content: 37.35

Gene sequence:

>921_bases
TTGAGGAGAAAAATTGCTTTATTTTTAGCTCTTATTTTTGTTGGAGTATCTCTTGTTTCATGTTCTTCTAAAAAAGAAGC
TGTATCTGGGGATGTCGTCGCAGTAGTGAATGGAGAAAAGATTACTAATGCGGAGTACCAGCAAATTTTTGAACAGGTGA
AAGAGCAGATTGAAAGTGCACCCACCTACACAAAAGACATTTGGAATCAGGACTATCAAGGCAAAAAATTTCTGGATTTT
GTTAAAGAAAATGTTTTAGACAGCCTTGTGGCGCAAAAGCTTCTTGTTCAGGAGGCTAAAAAGAAAAACATCACTGTCAC
GGATAAGGAAGTAGAAGAAGAGTATAACAAGGAAAAGCAATTTAACAGCAAAGTTACAAAGGAGCAGATAAGAGAATATC
TTTTGATAGACAAGCTTTTAGCAGAGTACACTAAGGATGTAAAAGTTACTGATGAGGAGCTTAAAAAATACTATGACGAG
CACAAAGAGAGTTTTGAGGTCATGAGAGCTCGTCACATCCTCGTGGCTGATGAGAAGACGGCAGAAGATATATATCAAAG
GCTTATGAAAGGTGAAGACTTTGCCGCTTTAGCAAAAGAATATTCCATTGATACAGCTACAAAGGATAATGGCGGAGATT
TGGGAGAATTTCCCCATGGGGTGATGGTGCCAGAATTTGAGGAAGCAGCATTTTCCTTAAAGCTAGGGGAGATTTCTAAA
CCTGTAAAGACGCAGTACGGTTATCACATAATAAAATCAGAAGGAATTACTGTGAAGCCTTTTGATGAAGTGAAAGGAAC
AATTGAGAGCTACCTTTTAAATGACAAAAAGAACAAGGTCATAAAAGAAAAGTACGACGAACTCGTAAAGGCTTCTAAGA
TACAGAAATTTCCTGAAAATATAAAAGTGAAAGTAGGGTAG

Upstream 100 bases:

>100_bases
AGAATTGATAGAACTTTTGGAGAAAATGAAAGATTTGCAGTTGGCAAAGAAATAAGATATAATAAAGCTATGTCAAATTT
AAAATTAGGAGGCTGTAATT

Downstream 100 bases:

>100_bases
AGCTGGCATATAATTGCCAGCTCTTTTTTGCGCATAAATTTATGGAAAAATATAAATACTAATCTTGAGCTAAAAATTTT
AGGAAATGGAGGTATTTACT

Product: parvulin-like peptidyl-prolyl isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MRRKIALFLALIFVGVSLVSCSSKKEAVSGDVVAVVNGEKITNAEYQQIFEQVKEQIESAPTYTKDIWNQDYQGKKFLDF
VKENVLDSLVAQKLLVQEAKKKNITVTDKEVEEEYNKEKQFNSKVTKEQIREYLLIDKLLAEYTKDVKVTDEELKKYYDE
HKESFEVMRARHILVADEKTAEDIYQRLMKGEDFAALAKEYSIDTATKDNGGDLGEFPHGVMVPEFEEAAFSLKLGEISK
PVKTQYGYHIIKSEGITVKPFDEVKGTIESYLLNDKKNKVIKEKYDELVKASKIQKFPENIKVKVG

Sequences:

>Translated_306_residues
MRRKIALFLALIFVGVSLVSCSSKKEAVSGDVVAVVNGEKITNAEYQQIFEQVKEQIESAPTYTKDIWNQDYQGKKFLDF
VKENVLDSLVAQKLLVQEAKKKNITVTDKEVEEEYNKEKQFNSKVTKEQIREYLLIDKLLAEYTKDVKVTDEELKKYYDE
HKESFEVMRARHILVADEKTAEDIYQRLMKGEDFAALAKEYSIDTATKDNGGDLGEFPHGVMVPEFEEAAFSLKLGEISK
PVKTQYGYHIIKSEGITVKPFDEVKGTIESYLLNDKKNKVIKEKYDELVKASKIQKFPENIKVKVG
>Mature_306_residues
MRRKIALFLALIFVGVSLVSCSSKKEAVSGDVVAVVNGEKITNAEYQQIFEQVKEQIESAPTYTKDIWNQDYQGKKFLDF
VKENVLDSLVAQKLLVQEAKKKNITVTDKEVEEEYNKEKQFNSKVTKEQIREYLLIDKLLAEYTKDVKVTDEELKKYYDE
HKESFEVMRARHILVADEKTAEDIYQRLMKGEDFAALAKEYSIDTATKDNGGDLGEFPHGVMVPEFEEAAFSLKLGEISK
PVKTQYGYHIIKSEGITVKPFDEVKGTIESYLLNDKKNKVIKEKYDELVKASKIQKFPENIKVKVG

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain

Homologues:

Organism=Escherichia coli, GI1786645, Length=273, Percent_Identity=29.6703296703297, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790211, Length=83, Percent_Identity=50.6024096385542, Blast_Score=82, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17537235, Length=102, Percent_Identity=38.2352941176471, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322478, Length=66, Percent_Identity=51.5151515151515, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRSA_THETN (Q8R760)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_624084.1
- ProteinModelPortal:   Q8R760
- SMR:   Q8R760
- GeneID:   996134
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE2564
- NMPDR:   fig|273068.3.peg.2037
- HOGENOM:   HBG712792
- OMA:   YHIIKIN
- ProtClustDB:   CLSK901770
- BioCyc:   TTEN273068:TTE2564-MONOMER
- BRENDA:   5.2.1.8
- HAMAP:   MF_01145
- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 35106; Mature: 35106

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2; PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKIALFLALIFVGVSLVSCSSKKEAVSGDVVAVVNGEKITNAEYQQIFEQVKEQIESA
CCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHC
PTYTKDIWNQDYQGKKFLDFVKENVLDSLVAQKLLVQEAKKKNITVTDKEVEEEYNKEKQ
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FNSKVTKEQIREYLLIDKLLAEYTKDVKVTDEELKKYYDEHKESFEVMRARHILVADEKT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCHH
AEDIYQRLMKGEDFAALAKEYSIDTATKDNGGDLGEFPHGVMVPEFEEAAFSLKLGEISK
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEHHHCCC
PVKTQYGYHIIKSEGITVKPFDEVKGTIESYLLNDKKNKVIKEKYDELVKASKIQKFPEN
CHHHHCCEEEEECCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
IKVKVG
CEEECC
>Mature Secondary Structure
MRRKIALFLALIFVGVSLVSCSSKKEAVSGDVVAVVNGEKITNAEYQQIFEQVKEQIESA
CCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHC
PTYTKDIWNQDYQGKKFLDFVKENVLDSLVAQKLLVQEAKKKNITVTDKEVEEEYNKEKQ
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FNSKVTKEQIREYLLIDKLLAEYTKDVKVTDEELKKYYDEHKESFEVMRARHILVADEKT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCHH
AEDIYQRLMKGEDFAALAKEYSIDTATKDNGGDLGEFPHGVMVPEFEEAAFSLKLGEISK
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEHHHCCC
PVKTQYGYHIIKSEGITVKPFDEVKGTIESYLLNDKKNKVIKEKYDELVKASKIQKFPEN
CHHHHCCEEEEECCCCEECCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
IKVKVG
CEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336