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The map label for this gene is Ppx1 [H]

Identifier: 20808804

GI number: 20808804

Start: 2336061

End: 2337680

Strand: Direct

Name: Ppx1 [H]

Synonym: TTE2447

Alternate gene names: 20808804

Gene position: 2336061-2337680 (Clockwise)

Preceding gene: 20808796

Following gene: 20808812

Centisome position: 86.86

GC content: 38.77

Gene sequence:

>1620_bases
ATGAAGACGGTATATGTATGTGGTCATAAAAACCCGGACACTGACTCAATTTGCTCTGCTATAGCATATGCTCACTTAAA
AAGAATAACAGAAGGGATAAACGCTATCCCCGTGCGGCTTGGACCTATAAATAGAGAGACAAAGTTTGTGCTGGATTACT
TTGGCATAGAAGAACCAATCTTTATTGAAAATGTATATACTCAGGTTCAAGATATAAAGTTTGACAAACCTTTAATATTT
AAAGAAAACACTTCTATGTTCGAAGCCTGGAACGCAATGATGGAGAAAAACATAAGGACACTTGCAGTAGTGGATGACGA
GAATAAACTCATAGGAATAGCAACAGTAGGGGATTTAGCAAAAGCTTACCTCTCTTCTGCCCACGAACTATCTAAATACA
GAATACCAATTGAAAACCTACTTGCAACTTTAAAAGGAGAGATTTTATTAAGATACCTAGACTATATAGAAGGAAACATA
CTGGTAGCCGCCATGTCAAAAGAAAATGTCCTAAAGAGGATAAAAGAAGGAGATACGTTGATAGTGGGAGACAGAGAAGA
CATCCAGGAAGCCGCAATTCAAAAAGGCGTAAAAGCTTTGATAATAACGGGAAACAATCAAGTCTCAGAAAAAATTTTAG
ACTTAGCTGAAAAGCATGAAGTAACTATAATAAAAGTCTCCCCTGACACCTTTGATACGGTAAAACTTTTAAATCAAAGC
ATTCCTCTGTCTTATGTCATAAAAAAAGAAGACATAGTGAGCTTCAGACTCACTGATTACATTGACGATGTAAAAGAGGT
AATGTTAAAATATAGGTACCGCAATTTCCCCGTATTAGACGAGGAAGGAAGAGTTGTAGGGCTTTTAGGAAGGAGGCACA
TCCTAGACTACGAAAGAAAAAATGTAATTTTAGTCGACCACAATGAGTTTTCCCAAGCTGTGGAAGGAATAGAACAAGCG
AGAATACTCGAGATAATTGACCATCATAGACTTGGCACAATCGAAACAGATCAGCCGATACTTTTTAGAAACCATCCCGT
AGGCTCTACAGCCACCATAATAAACCGGCTTTATGAAGAAAAAGGGCTGATTCCCGACCCGAAAATAGCTGGCATAATGT
GCGCTGCCATACTATCTGACACGCTTGTTTTCAAATCACCTACCTGCACCCCTGAAGATGTGAGAGCCGCGAAAAAGCTT
GCAGAAATAGCAGAAATAGATATAAACGAGTTCGGGAACCAGATGTTCAAAGCAGGAACTTCATTAGAGGGCAAAACAGT
AGAAGAAATCTTCTACACCGACTTTAAAGAATTCACAGTAAACAAATACAAGATAGGCATAGGACAGGTAAACACCTTAG
CCGATCCAGGGGAACTCAAAAAAGACCTCATCTCCTTCATGGAAAAAGTAAGAAGTGATAAAGGATACGACATACTGCTT
CTTATGCTGACAGACATCATAAACGAAGGGTCAGAAATCCTCTTTGTAGGCGATAACAAAGAACTCCTAGAAAGGGCCTT
TGATGTAAAGATACAAAACAACAGTTTCTATCTTCCTTACGTGATTTCTCGCAAAAAGCAGGTACTTCCCCCTCTTGTAA
AAGCGATAAACACTCATTAG

Upstream 100 bases:

>100_bases
CTTTGTATAGTAATTACCATTTACATCTCCTCCTTTTCCTGTTATATTATATTTATCCACAACCACAACCATGAAAATTA
AAAACAGGGGCGATGCAGAA

Downstream 100 bases:

>100_bases
TGTTTATCGCTTTACATATCTTATTATGTCTTTGAAGCTACCAAATCGAAAATATTTAATTCCTTTTTCCTCGCAGTAAT
CTGCTAACACGTCTTTAGCA

Product: putative manganese-dependent inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MKTVYVCGHKNPDTDSICSAIAYAHLKRITEGINAIPVRLGPINRETKFVLDYFGIEEPIFIENVYTQVQDIKFDKPLIF
KENTSMFEAWNAMMEKNIRTLAVVDDENKLIGIATVGDLAKAYLSSAHELSKYRIPIENLLATLKGEILLRYLDYIEGNI
LVAAMSKENVLKRIKEGDTLIVGDREDIQEAAIQKGVKALIITGNNQVSEKILDLAEKHEVTIIKVSPDTFDTVKLLNQS
IPLSYVIKKEDIVSFRLTDYIDDVKEVMLKYRYRNFPVLDEEGRVVGLLGRRHILDYERKNVILVDHNEFSQAVEGIEQA
RILEIIDHHRLGTIETDQPILFRNHPVGSTATIINRLYEEKGLIPDPKIAGIMCAAILSDTLVFKSPTCTPEDVRAAKKL
AEIAEIDINEFGNQMFKAGTSLEGKTVEEIFYTDFKEFTVNKYKIGIGQVNTLADPGELKKDLISFMEKVRSDKGYDILL
LMLTDIINEGSEILFVGDNKELLERAFDVKIQNNSFYLPYVISRKKQVLPPLVKAINTH

Sequences:

>Translated_539_residues
MKTVYVCGHKNPDTDSICSAIAYAHLKRITEGINAIPVRLGPINRETKFVLDYFGIEEPIFIENVYTQVQDIKFDKPLIF
KENTSMFEAWNAMMEKNIRTLAVVDDENKLIGIATVGDLAKAYLSSAHELSKYRIPIENLLATLKGEILLRYLDYIEGNI
LVAAMSKENVLKRIKEGDTLIVGDREDIQEAAIQKGVKALIITGNNQVSEKILDLAEKHEVTIIKVSPDTFDTVKLLNQS
IPLSYVIKKEDIVSFRLTDYIDDVKEVMLKYRYRNFPVLDEEGRVVGLLGRRHILDYERKNVILVDHNEFSQAVEGIEQA
RILEIIDHHRLGTIETDQPILFRNHPVGSTATIINRLYEEKGLIPDPKIAGIMCAAILSDTLVFKSPTCTPEDVRAAKKL
AEIAEIDINEFGNQMFKAGTSLEGKTVEEIFYTDFKEFTVNKYKIGIGQVNTLADPGELKKDLISFMEKVRSDKGYDILL
LMLTDIINEGSEILFVGDNKELLERAFDVKIQNNSFYLPYVISRKKQVLPPLVKAINTH
>Mature_539_residues
MKTVYVCGHKNPDTDSICSAIAYAHLKRITEGINAIPVRLGPINRETKFVLDYFGIEEPIFIENVYTQVQDIKFDKPLIF
KENTSMFEAWNAMMEKNIRTLAVVDDENKLIGIATVGDLAKAYLSSAHELSKYRIPIENLLATLKGEILLRYLDYIEGNI
LVAAMSKENVLKRIKEGDTLIVGDREDIQEAAIQKGVKALIITGNNQVSEKILDLAEKHEVTIIKVSPDTFDTVKLLNQS
IPLSYVIKKEDIVSFRLTDYIDDVKEVMLKYRYRNFPVLDEEGRVVGLLGRRHILDYERKNVILVDHNEFSQAVEGIEQA
RILEIIDHHRLGTIETDQPILFRNHPVGSTATIINRLYEEKGLIPDPKIAGIMCAAILSDTLVFKSPTCTPEDVRAAKKL
AEIAEIDINEFGNQMFKAGTSLEGKTVEEIFYTDFKEFTVNKYKIGIGQVNTLADPGELKKDLISFMEKVRSDKGYDILL
LMLTDIINEGSEILFVGDNKELLERAFDVKIQNNSFYLPYVISRKKQVLPPLVKAINTH

Specific function: Unknown

COG id: COG1227

COG function: function code C; Inorganic pyrophosphatase/exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001807
- InterPro:   IPR000644
- InterPro:   IPR004097
- InterPro:   IPR010766
- InterPro:   IPR001667 [H]

Pfam domain/function: PF00571 CBS; PF01368 DHH; PF02833 DHHA2; PF07085 DRTGG [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 61070; Mature: 61070

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVYVCGHKNPDTDSICSAIAYAHLKRITEGINAIPVRLGPINRETKFVLDYFGIEEPI
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEHHHCCCCCE
FIENVYTQVQDIKFDKPLIFKENTSMFEAWNAMMEKNIRTLAVVDDENKLIGIATVGDLA
EHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEHHHHH
KAYLSSAHELSKYRIPIENLLATLKGEILLRYLDYIEGNILVAAMSKENVLKRIKEGDTL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCEE
IVGDREDIQEAAIQKGVKALIITGNNQVSEKILDLAEKHEVTIIKVSPDTFDTVKLLNQS
EECCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCC
IPLSYVIKKEDIVSFRLTDYIDDVKEVMLKYRYRNFPVLDEEGRVVGLLGRRHILDYERK
CCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHCCCCCC
NVILVDHNEFSQAVEGIEQARILEIIDHHRLGTIETDQPILFRNHPVGSTATIINRLYEE
CEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHH
KGLIPDPKIAGIMCAAILSDTLVFKSPTCTPEDVRAAKKLAEIAEIDINEFGNQMFKAGT
CCCCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
SLEGKTVEEIFYTDFKEFTVNKYKIGIGQVNTLADPGELKKDLISFMEKVRSDKGYDILL
CCCCCHHHHHHHHCHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHH
LMLTDIINEGSEILFVGDNKELLERAFDVKIQNNSFYLPYVISRKKQVLPPLVKAINTH
HHHHHHHCCCCEEEEECCCHHHHHHHHCEEECCCCEEECHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTVYVCGHKNPDTDSICSAIAYAHLKRITEGINAIPVRLGPINRETKFVLDYFGIEEPI
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEHHHCCCCCE
FIENVYTQVQDIKFDKPLIFKENTSMFEAWNAMMEKNIRTLAVVDDENKLIGIATVGDLA
EHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEHHHHH
KAYLSSAHELSKYRIPIENLLATLKGEILLRYLDYIEGNILVAAMSKENVLKRIKEGDTL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCCCEE
IVGDREDIQEAAIQKGVKALIITGNNQVSEKILDLAEKHEVTIIKVSPDTFDTVKLLNQS
EECCHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCC
IPLSYVIKKEDIVSFRLTDYIDDVKEVMLKYRYRNFPVLDEEGRVVGLLGRRHILDYERK
CCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHCCCCCC
NVILVDHNEFSQAVEGIEQARILEIIDHHRLGTIETDQPILFRNHPVGSTATIINRLYEE
CEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHH
KGLIPDPKIAGIMCAAILSDTLVFKSPTCTPEDVRAAKKLAEIAEIDINEFGNQMFKAGT
CCCCCCCHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
SLEGKTVEEIFYTDFKEFTVNKYKIGIGQVNTLADPGELKKDLISFMEKVRSDKGYDILL
CCCCCHHHHHHHHCHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEHH
LMLTDIINEGSEILFVGDNKELLERAFDVKIQNNSFYLPYVISRKKQVLPPLVKAINTH
HHHHHHHCCCCEEEEECCCHHHHHHHHCEEECCCCEEECHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]