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The map label for this gene is TrxB2 [H]

Identifier: 20808597

GI number: 20808597

Start: 2128814

End: 2129731

Strand: Reverse

Name: TrxB2 [H]

Synonym: TTE2220

Alternate gene names: 20808597

Gene position: 2129731-2128814 (Counterclockwise)

Preceding gene: 20808598

Following gene: 20808595

Centisome position: 79.19

GC content: 41.29

Gene sequence:

>918_bases
ATGTACGACCTAATAATTTTGGGTGGAGGACCTGCAGGGCTTACAGCCGGACTTTACGCTGCAAGGTCAAGGCTCAAAAC
AGTGCTTATTGAGAAGACATATCTTGGAGGTCAGATTGTAAATACCTATCAGCTGGAGAATTATCCGGGCTACGAAGAGA
TTACAGGTGCAGACCTAGTGGCGAAAATGGAGGCTCAGGTGAGAAAGCACGGGCTTGAGATAGTTTTAGAGGATGTAGAA
AGCCTTGATATTACAGGAGAGATAAAGAGAGTAAAGACAGCCAACAATAAAGTATATGAGGCGAAGGCTATAATACTTGC
AATGGGAGCAACTCCTAGAAAGTTAGGAGTTCCCAATGAGGATAGATTTATAGGGGCAGGTATTTCTTTCTGTGCAACCT
GTGATGGTGCTTTTTACAGAGATGCAGTTGTTGCTGTCATAGGAGGAGGAAATACAGCAGTAGAAGATGCTCTTTATCTT
ACGAAATTTGCTAAAAAAGTCTACATAATTCACAGGAGAGACCAGTTAAGAGCTACCAAGATAGAGCAGGAAAAGGCTTT
TGCCAATGAAAAGATAGAATTCATTTGGAATACTGTAGTAGTTGATGTTGAGGGAGAGTATGGAGTAGAGAGAATTAGGC
TTAAAAATGTGAAGACAGGGGAAGAGAGTACGTTAAATGTGGATGGAGTATTTGTCGCTATAGGCTATGACCCGAATACA
GAGCTTGTAAAGGGAATTGTAGAGTTAGATGAGTATGGGTATATAATCACTGATGATGATATGAAAACCAATATACCAGG
AGTTTTTGCTGCAGGAGATATAAGGCACAAGCTTTTAAGACAGGTGATAACAGCTGCAGGAGATGGAGCGACAGCCGCTT
ACGCTGCAGAAAAGTATATAGAAAGCCTAAAGAAATAG

Upstream 100 bases:

>100_bases
ATAGAGAAAGTTTGTGATATAATTATGGAAGCAGTAGTTTTTACTGCTTCCATAAATTTTATGGCAATTAATTTAGTTCA
AAAGGAGGAGTGATTTTATT

Downstream 100 bases:

>100_bases
TCAGGAGAAGTCTCCTGACTATTTTTCTTCTTCCTTGTCTTGTGGTTCTTTGTCAGTAATTATTTCCTGAGAGGTGGCAG
CCTGCTGTGAAGTAGGGATT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MYDLIILGGGPAGLTAGLYAARSRLKTVLIEKTYLGGQIVNTYQLENYPGYEEITGADLVAKMEAQVRKHGLEIVLEDVE
SLDITGEIKRVKTANNKVYEAKAIILAMGATPRKLGVPNEDRFIGAGISFCATCDGAFYRDAVVAVIGGGNTAVEDALYL
TKFAKKVYIIHRRDQLRATKIEQEKAFANEKIEFIWNTVVVDVEGEYGVERIRLKNVKTGEESTLNVDGVFVAIGYDPNT
ELVKGIVELDEYGYIITDDDMKTNIPGVFAAGDIRHKLLRQVITAAGDGATAAYAAEKYIESLKK

Sequences:

>Translated_305_residues
MYDLIILGGGPAGLTAGLYAARSRLKTVLIEKTYLGGQIVNTYQLENYPGYEEITGADLVAKMEAQVRKHGLEIVLEDVE
SLDITGEIKRVKTANNKVYEAKAIILAMGATPRKLGVPNEDRFIGAGISFCATCDGAFYRDAVVAVIGGGNTAVEDALYL
TKFAKKVYIIHRRDQLRATKIEQEKAFANEKIEFIWNTVVVDVEGEYGVERIRLKNVKTGEESTLNVDGVFVAIGYDPNT
ELVKGIVELDEYGYIITDDDMKTNIPGVFAAGDIRHKLLRQVITAAGDGATAAYAAEKYIESLKK
>Mature_305_residues
MYDLIILGGGPAGLTAGLYAARSRLKTVLIEKTYLGGQIVNTYQLENYPGYEEITGADLVAKMEAQVRKHGLEIVLEDVE
SLDITGEIKRVKTANNKVYEAKAIILAMGATPRKLGVPNEDRFIGAGISFCATCDGAFYRDAVVAVIGGGNTAVEDALYL
TKFAKKVYIIHRRDQLRATKIEQEKAFANEKIEFIWNTVVVDVEGEYGVERIRLKNVKTGEESTLNVDGVFVAIGYDPNT
ELVKGIVELDEYGYIITDDDMKTNIPGVFAAGDIRHKLLRQVITAAGDGATAAYAAEKYIESLKK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=311, Percent_Identity=44.3729903536978, Blast_Score=241, Evalue=3e-65,
Organism=Escherichia coli, GI87081763, Length=306, Percent_Identity=33.3333333333333, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1789606, Length=338, Percent_Identity=26.9230769230769, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=42.3566878980892, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6321898, Length=314, Percent_Identity=40.1273885350318, Blast_Score=228, Evalue=1e-60,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33382; Mature: 33382

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDLIILGGGPAGLTAGLYAARSRLKTVLIEKTYLGGQIVNTYQLENYPGYEEITGADLV
CEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEECCCCCHHHCCCHHHH
AKMEAQVRKHGLEIVLEDVESLDITGEIKRVKTANNKVYEAKAIILAMGATPRKLGVPNE
HHHHHHHHHCCHHHEEHHHHHCCCCCCEEEEECCCCCEEEEEEEEEEECCCCHHCCCCCC
DRFIGAGISFCATCDGAFYRDAVVAVIGGGNTAVEDALYLTKFAKKVYIIHRRDQLRATK
CCEEECCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHEEEEEEECCCHHHHH
IEQEKAFANEKIEFIWNTVVVDVEGEYGVERIRLKNVKTGEESTLNVDGVFVAIGYDPNT
HHHHHHHHCCCEEEEEEEEEEEECCCCCCEEEEEECCCCCCCCEEEECEEEEEEECCCCH
ELVKGIVELDEYGYIITDDDMKTNIPGVFAAGDIRHKLLRQVITAAGDGATAAYAAEKYI
HHHHHHHHHHHCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ESLKK
HHHCC
>Mature Secondary Structure
MYDLIILGGGPAGLTAGLYAARSRLKTVLIEKTYLGGQIVNTYQLENYPGYEEITGADLV
CEEEEEECCCCHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEEEECCCCCHHHCCCHHHH
AKMEAQVRKHGLEIVLEDVESLDITGEIKRVKTANNKVYEAKAIILAMGATPRKLGVPNE
HHHHHHHHHCCHHHEEHHHHHCCCCCCEEEEECCCCCEEEEEEEEEEECCCCHHCCCCCC
DRFIGAGISFCATCDGAFYRDAVVAVIGGGNTAVEDALYLTKFAKKVYIIHRRDQLRATK
CCEEECCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHEEEEEEECCCHHHHH
IEQEKAFANEKIEFIWNTVVVDVEGEYGVERIRLKNVKTGEESTLNVDGVFVAIGYDPNT
HHHHHHHHCCCEEEEEEEEEEEECCCCCCEEEEEECCCCCCCCEEEECEEEEEEECCCCH
ELVKGIVELDEYGYIITDDDMKTNIPGVFAAGDIRHKLLRQVITAAGDGATAAYAAEKYI
HHHHHHHHHHHCCEEEECCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ESLKK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529640 [H]