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The map label for this gene is glmM

Identifier: 20808573

GI number: 20808573

Start: 2101664

End: 2103007

Strand: Reverse

Name: glmM

Synonym: TTE2191

Alternate gene names: 20808573

Gene position: 2103007-2101664 (Counterclockwise)

Preceding gene: 20808574

Following gene: 20808572

Centisome position: 78.19

GC content: 39.06

Gene sequence:

>1344_bases
ATGGGAAGGCTTTTTGGGACTGACGGTGTGAGGGGAATAGCGAACAAGGAATTAACTCCACAACTGGCTTTTGAGTTGGG
GCGGGCAGGAGCTTATGTCCTTACAGAGGGAAGTCACAGGCCAAAGGTTGTGGTGGGAAAGGACAGCAGGATTTCAAGCG
ATATGTTGGAATGTGCTCTTATTGCTGGGCTTACATCTCTTGGAGCAGAAGTGGTAAGTGTAGGAATAATTCCTACGCCG
GCAGTAGCTTATTTGACTAGGCTATATAAGGCAGATGCTGGAGTTATGATTTCAGCTTCTCACAATCCGATTGAGTATAA
TGGAATAAAATTCTTTGATAAGTTTGGCTACAAATTGCCTGATAAGCTGGAAGACAGGATAGAGGAAATTATAAATGAAA
AAAAAGAACTTCCTGTTCCTACTGGCATTGGAATAGGCAGAAGAAAAGAAAGCTTGACTTCTCACAGGGATTATATAGAA
TTTTTAAAGTCTACCATTGATACAGACTTAAAAGGGCTTAAAATAGTGATTGACTGTGCTTATGGGGCAAGCAGCACAGT
AGCTCCTATTTTGTTTAAAGAATTAGGAGCAGAGGTAATTGCTTATGCGGCAGAGCTTTTAGGAGAAAAAATCAATGTAG
GCTGTGGATCCACGCACCCTGAGAAATTGCAGCAGCTTGTAGTAGAACATAAAGCGGACCTGGGGCTTGCTTTTGATGGA
GATGCGGACAGATTAATTGCAGTTGACGAAAAAGGGAATATAGTAGACGGAGACCATATAATGGCTATATGTGCTATTGA
TATGAAAAGCAAAGGGAAATTAAAACACAATACTGTGGTAGCGACAGTCATGAGTAACATAGGATTTGAAATTGCTTTAA
AGGAGCATGGAATTAAGCTTATAAGGACAAAGGTAGGAGATAGATATGTATTAGAGGAAATGATAAAAGGTGGATATTCT
ATTGGAGGAGAACAGTCAGGACATATAATTTTCATAGATGACAATACTACAGGAGATGGAGAGATAACAGCTTTAAAACT
TTGTTCAATAATGAAACATACAGGTAAAAAACTGTCTGAACTTGCTTCTTGCATGACTACCTATCCTCAGGTACTTGTAA
ATGCCAAAGTGAAAAATGAGCTTAAAGAAAAATATCTAGAAGATGAAGACATAAAGAGAGAAATTGAAAAGCTAGAAAAA
GAAATGGAAGGGAAAGGAAGAGTTCTCATAAGACCATCTGGCACAGAACCTCTCATAAGAGTTATGGTAGAGGGTGAAGA
TTACGCTAAAATCAGCCAGATGGCAAAAGAGCTGGCTGATTTGATAGAAAGAAAATTGAACTGA

Upstream 100 bases:

>100_bases
AGAATGAAGGAAATGCTTGCAGAATAAAAAAGGTTTTTTTGCACAATAAAGACAACTGTGATAAAATATTATCGTACGTT
TTACAGAAAGGGGATAGAGA

Downstream 100 bases:

>100_bases
TTTTTTGAAAGGAGGGATGCCTATAGAGGAAGATGTAGAGTCGAGATTTAATGTAAGCTTTAATTTAGAAGCGCCTGGAC
TTAAAGCCTTAAGGCTTTAA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MGRLFGTDGVRGIANKELTPQLAFELGRAGAYVLTEGSHRPKVVVGKDSRISSDMLECALIAGLTSLGAEVVSVGIIPTP
AVAYLTRLYKADAGVMISASHNPIEYNGIKFFDKFGYKLPDKLEDRIEEIINEKKELPVPTGIGIGRRKESLTSHRDYIE
FLKSTIDTDLKGLKIVIDCAYGASSTVAPILFKELGAEVIAYAAELLGEKINVGCGSTHPEKLQQLVVEHKADLGLAFDG
DADRLIAVDEKGNIVDGDHIMAICAIDMKSKGKLKHNTVVATVMSNIGFEIALKEHGIKLIRTKVGDRYVLEEMIKGGYS
IGGEQSGHIIFIDDNTTGDGEITALKLCSIMKHTGKKLSELASCMTTYPQVLVNAKVKNELKEKYLEDEDIKREIEKLEK
EMEGKGRVLIRPSGTEPLIRVMVEGEDYAKISQMAKELADLIERKLN

Sequences:

>Translated_447_residues
MGRLFGTDGVRGIANKELTPQLAFELGRAGAYVLTEGSHRPKVVVGKDSRISSDMLECALIAGLTSLGAEVVSVGIIPTP
AVAYLTRLYKADAGVMISASHNPIEYNGIKFFDKFGYKLPDKLEDRIEEIINEKKELPVPTGIGIGRRKESLTSHRDYIE
FLKSTIDTDLKGLKIVIDCAYGASSTVAPILFKELGAEVIAYAAELLGEKINVGCGSTHPEKLQQLVVEHKADLGLAFDG
DADRLIAVDEKGNIVDGDHIMAICAIDMKSKGKLKHNTVVATVMSNIGFEIALKEHGIKLIRTKVGDRYVLEEMIKGGYS
IGGEQSGHIIFIDDNTTGDGEITALKLCSIMKHTGKKLSELASCMTTYPQVLVNAKVKNELKEKYLEDEDIKREIEKLEK
EMEGKGRVLIRPSGTEPLIRVMVEGEDYAKISQMAKELADLIERKLN
>Mature_446_residues
GRLFGTDGVRGIANKELTPQLAFELGRAGAYVLTEGSHRPKVVVGKDSRISSDMLECALIAGLTSLGAEVVSVGIIPTPA
VAYLTRLYKADAGVMISASHNPIEYNGIKFFDKFGYKLPDKLEDRIEEIINEKKELPVPTGIGIGRRKESLTSHRDYIEF
LKSTIDTDLKGLKIVIDCAYGASSTVAPILFKELGAEVIAYAAELLGEKINVGCGSTHPEKLQQLVVEHKADLGLAFDGD
ADRLIAVDEKGNIVDGDHIMAICAIDMKSKGKLKHNTVVATVMSNIGFEIALKEHGIKLIRTKVGDRYVLEEMIKGGYSI
GGEQSGHIIFIDDNTTGDGEITALKLCSIMKHTGKKLSELASCMTTYPQVLVNAKVKNELKEKYLEDEDIKREIEKLEKE
MEGKGRVLIRPSGTEPLIRVMVEGEDYAKISQMAKELADLIERKLN

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=444, Percent_Identity=46.6216216216216, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1788361, Length=436, Percent_Identity=27.9816513761468, Blast_Score=133, Evalue=2e-32,
Organism=Drosophila melanogaster, GI17864244, Length=334, Percent_Identity=26.3473053892216, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_THETN (Q8R840)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623744.1
- ProteinModelPortal:   Q8R840
- SMR:   Q8R840
- GeneID:   997511
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE2191
- NMPDR:   fig|273068.3.peg.2330
- HOGENOM:   HBG644964
- OMA:   SAVMIHE
- ProtClustDB:   PRK14316
- BioCyc:   TTEN273068:TTE2191-MONOMER
- BRENDA:   5.4.2.10
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 48904; Mature: 48773

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 100-100

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLFGTDGVRGIANKELTPQLAFELGRAGAYVLTEGSHRPKVVVGKDSRISSDMLECAL
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHH
IAGLTSLGAEVVSVGIIPTPAVAYLTRLYKADAGVMISASHNPIEYNGIKFFDKFGYKLP
HHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHHHCCCCCC
DKLEDRIEEIINEKKELPVPTGIGIGRRKESLTSHRDYIEFLKSTIDTDLKGLKIVIDCA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
YGASSTVAPILFKELGAEVIAYAAELLGEKINVGCGSTHPEKLQQLVVEHKADLGLAFDG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECC
DADRLIAVDEKGNIVDGDHIMAICAIDMKSKGKLKHNTVVATVMSNIGFEIALKEHGIKL
CCCCEEEECCCCCEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEHHCCEEE
IRTKVGDRYVLEEMIKGGYSIGGEQSGHIIFIDDNTTGDGEITALKLCSIMKHTGKKLSE
EHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
LASCMTTYPQVLVNAKVKNELKEKYLEDEDIKREIEKLEKEMEGKGRVLIRPSGTEPLIR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEE
VMVEGEDYAKISQMAKELADLIERKLN
EEECCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GRLFGTDGVRGIANKELTPQLAFELGRAGAYVLTEGSHRPKVVVGKDSRISSDMLECAL
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCHHHHHHHHH
IAGLTSLGAEVVSVGIIPTPAVAYLTRLYKADAGVMISASHNPIEYNGIKFFDKFGYKLP
HHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHHHCCCCCC
DKLEDRIEEIINEKKELPVPTGIGIGRRKESLTSHRDYIEFLKSTIDTDLKGLKIVIDCA
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
YGASSTVAPILFKELGAEVIAYAAELLGEKINVGCGSTHPEKLQQLVVEHKADLGLAFDG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECC
DADRLIAVDEKGNIVDGDHIMAICAIDMKSKGKLKHNTVVATVMSNIGFEIALKEHGIKL
CCCCEEEECCCCCEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEHHCCEEE
IRTKVGDRYVLEEMIKGGYSIGGEQSGHIIFIDDNTTGDGEITALKLCSIMKHTGKKLSE
EHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
LASCMTTYPQVLVNAKVKNELKEKYLEDEDIKREIEKLEKEMEGKGRVLIRPSGTEPLIR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEE
VMVEGEDYAKISQMAKELADLIERKLN
EEECCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336