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The map label for this gene is yqaB [C]

Identifier: 20808387

GI number: 20808387

Start: 1932904

End: 1933578

Strand: Reverse

Name: yqaB [C]

Synonym: TTE1983

Alternate gene names: 20808387

Gene position: 1933578-1932904 (Counterclockwise)

Preceding gene: 20808388

Following gene: 20808386

Centisome position: 71.9

GC content: 35.11

Gene sequence:

>675_bases
ATGATTAAAGCAGTTATTTTTGACATGGATGGAGTAATGATTGACAGTGAACCTGTGCATCTTAAGCTTGAGAGAGAGTT
ATTTAGAGAACTGGGAGTTGAGATAACTGAAGAAGAACACATGACATTTGTAGGAAGTTCTTCTTATTACATGTGGGAAA
AAATTAAAGAACGGTTTAATTTAAAAGAAAGTGTAGAAGAGCTGGTAAGAAGAGACAGAAAAAGGTATTTAGACCACGTC
TTGAGCACTGGAGAAATTATTCCTGTGCCAGGAATACAGGAATTGGTTAAGAAGCTTTTTGAAAGGGAATACAAACTGGC
AGTGGCTTCTTCCTCTCCAATAGATGTGATAGAATTGGTGGTTCAAAAATTAAACTTAAAGAACTTTTTTGATATGTTAG
TTTCTGGAGATTATGTAAAAAAAAGCAAGCCGTATCCAGACATATTTTTATATACGGCTGAAAAGTTAAGAGTCAAGCCT
GAAGAATGTGTCGTAATAGAGGATTCTTACAATGGTGTTCATGCAGCTAAAAGCGCTGGAATGAAAGTTATAGGATTTGT
AAACCCCAATTCTGGAAATCAGGACTTATCAGAAGCAGATTTTATAGTAAAGAATTTAGGGGACGAAGTAGTAGAAATAA
TATCAGGGCTTGAAGAGGAGAAGGCTTTAAAATAA

Upstream 100 bases:

>100_bases
AACCGCCTGCTGGGGCTGGGAAAGCCTGAAGGGCGGACTACAAATACCCCAGCTATCTAAACTGTGCATTTTTGTACAGT
TTGGGTGACCAGGTGATGAA

Downstream 100 bases:

>100_bases
AAAAATGGTGCGCCTGACAGGAGTCGAACCTGCGACCTTTCGGTCCGGAGCCGAACGCTCTATCCACTGAGCTACAGGCG
CACGCTTTCCAAATTAAAGT

Product: phosphatase/phosphohexomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MIKAVIFDMDGVMIDSEPVHLKLERELFRELGVEITEEEHMTFVGSSSYYMWEKIKERFNLKESVEELVRRDRKRYLDHV
LSTGEIIPVPGIQELVKKLFEREYKLAVASSSPIDVIELVVQKLNLKNFFDMLVSGDYVKKSKPYPDIFLYTAEKLRVKP
EECVVIEDSYNGVHAAKSAGMKVIGFVNPNSGNQDLSEADFIVKNLGDEVVEIISGLEEEKALK

Sequences:

>Translated_224_residues
MIKAVIFDMDGVMIDSEPVHLKLERELFRELGVEITEEEHMTFVGSSSYYMWEKIKERFNLKESVEELVRRDRKRYLDHV
LSTGEIIPVPGIQELVKKLFEREYKLAVASSSPIDVIELVVQKLNLKNFFDMLVSGDYVKKSKPYPDIFLYTAEKLRVKP
EECVVIEDSYNGVHAAKSAGMKVIGFVNPNSGNQDLSEADFIVKNLGDEVVEIISGLEEEKALK
>Mature_224_residues
MIKAVIFDMDGVMIDSEPVHLKLERELFRELGVEITEEEHMTFVGSSSYYMWEKIKERFNLKESVEELVRRDRKRYLDHV
LSTGEIIPVPGIQELVKKLFEREYKLAVASSSPIDVIELVVQKLNLKNFFDMLVSGDYVKKSKPYPDIFLYTAEKLRVKP
EECVVIEDSYNGVHAAKSAGMKVIGFVNPNSGNQDLSEADFIVKNLGDEVVEIISGLEEEKALK

Specific function: Displays high phosphatase activity toward erythrose 4- phosphate, fructose 6-phosphate, 2-deoxyglucose 6-phosphate, and mannose 6-phosphate. May have a role in the intracellular metabolism of many phosphorylated carbohydrates [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily [H]

Homologues:

Organism=Homo sapiens, GI197382691, Length=214, Percent_Identity=28.9719626168224, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI207113149, Length=157, Percent_Identity=32.484076433121, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1789046, Length=181, Percent_Identity=32.0441988950276, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788021, Length=196, Percent_Identity=34.6938775510204, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789787, Length=230, Percent_Identity=27.8260869565217, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787576, Length=207, Percent_Identity=28.0193236714976, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1790151, Length=191, Percent_Identity=27.2251308900524, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082080, Length=208, Percent_Identity=27.4038461538462, Blast_Score=64, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554716, Length=195, Percent_Identity=29.7435897435897, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17137324, Length=213, Percent_Identity=30.0469483568075, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI116008157, Length=214, Percent_Identity=29.9065420560748, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20129151, Length=218, Percent_Identity=27.5229357798165, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI45550911, Length=194, Percent_Identity=28.8659793814433, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 25622; Mature: 25622

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAVIFDMDGVMIDSEPVHLKLERELFRELGVEITEEEHMTFVGSSSYYMWEKIKERFN
CCEEEEEECCCEEECCCCCEEEHHHHHHHHHCCEEECCCCEEEECCCCHHHHHHHHHHCC
LKESVEELVRRDRKRYLDHVLSTGEIIPVPGIQELVKKLFEREYKLAVASSSPIDVIELV
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHH
VQKLNLKNFFDMLVSGDYVKKSKPYPDIFLYTAEKLRVKPEECVVIEDSYNGVHAAKSAG
HHHHCHHHHHHHHHCCCHHHCCCCCCCEEEEEHHHHCCCCCCEEEEECCCCCHHHHHHCC
MKVIGFVNPNSGNQDLSEADFIVKNLGDEVVEIISGLEEEKALK
CEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MIKAVIFDMDGVMIDSEPVHLKLERELFRELGVEITEEEHMTFVGSSSYYMWEKIKERFN
CCEEEEEECCCEEECCCCCEEEHHHHHHHHHCCEEECCCCEEEECCCCHHHHHHHHHHCC
LKESVEELVRRDRKRYLDHVLSTGEIIPVPGIQELVKKLFEREYKLAVASSSPIDVIELV
HHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHH
VQKLNLKNFFDMLVSGDYVKKSKPYPDIFLYTAEKLRVKPEECVVIEDSYNGVHAAKSAG
HHHHCHHHHHHHHHCCCHHHCCCCCCCEEEEEHHHHCCCCCCEEEEECCCCCHHHHHHCC
MKVIGFVNPNSGNQDLSEADFIVKNLGDEVVEIISGLEEEKALK
CEEEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]