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The map label for this gene is FtsX [H]

Identifier: 20808380

GI number: 20808380

Start: 1925724

End: 1926611

Strand: Reverse

Name: FtsX [H]

Synonym: TTE1976

Alternate gene names: 20808380

Gene position: 1926611-1925724 (Counterclockwise)

Preceding gene: 20808381

Following gene: 20808379

Centisome position: 71.64

GC content: 38.4

Gene sequence:

>888_bases
ATGCTCTTTAGAAATTTTAGATACTTCATAAAAGAAGGTTTTAGCAATCTGGCTAGAAACAGATTGATGACTGTAGCTTC
TGTCACCTCTGTGATGGCTGCTCTTGTCATACTCGGAATGTTTTTGCTGATAATCTTAAATGTAAACCATATGGCATATC
AAGTTGAATCTCAGCTGGAACTTAAGGCTTTTCTAAAAGATGACCTTTCGGGAGAGCAGATACAAAGAATAGGAGAAGAG
ATCAAGGGAATAGATGGAGTTTCTTCTGTGGTTTTCGAATCAAAAGAGCAGGCTTTGCAGAAATTTAAAAAGCAGCTGGG
GGAAAAAAGCTATCTTTTAGAAGGTCTTGAGAAGGACAACCCCCTCCCACAGTCCTATATAGTTAAAGTAAAAGACGCTA
ATCTCATAAAAGATATTGCCGATGAAATAAAAGGGATAAATGGTGTTGACAAAGTAAGCTATGGACAGGATGTGGTGGAA
AAGCTTCTCGGCATAATCAGGATTATAAGAATTGTAGGACTTGCAATAATTAGCATTTTGTTTGTCATCTCAATTGTCAT
AATTTCTAACACAATTAAATTAGGCGTTTTTGCAAGGAGAAGAGAAATAAACATAATGAAGTACATCGGAGCGACAGACT
GGTTCATAAGGTGGCCCTTTTTAATAGAAGGGATAGTTTTGGGTTTGCTGGGGGCACTGCTTTCAGTAGGTGTTCTGGCT
TTGATGTACGGGTATACTTTGGACTATGTCAACAGCCGTTTGATAGTTTTTAACTTACTGCCTTTGTCCGATGTCATCAA
GGACATGGCTTTGTATTTTGCGCTTTTAGGGTCTTTGATTGGCGCTATTGGCAGCGGCCTTTCTATAAAGAGGTTCTTAA
ATGTCTAA

Upstream 100 bases:

>100_bases
GCTACCCATGCTAAAGACATAGTTGATGCGATGAAGAAAAGAGTTATAGCTCTTGAAAAAGGGAACATAGTTAGGGACGA
AGCAAGGGGTGTATACGGAT

Downstream 100 bases:

>100_bases
AATTTACAAGGGGGAAGTGACATTGCAAAAGTACAAGTTAAAATGGCTTATATTTGCTCTTGTCTTCTTAGTGACGGCTC
TTTTTGCATCTTACCCGAGG

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLFRNFRYFIKEGFSNLARNRLMTVASVTSVMAALVILGMFLLIILNVNHMAYQVESQLELKAFLKDDLSGEQIQRIGEE
IKGIDGVSSVVFESKEQALQKFKKQLGEKSYLLEGLEKDNPLPQSYIVKVKDANLIKDIADEIKGINGVDKVSYGQDVVE
KLLGIIRIIRIVGLAIISILFVISIVIISNTIKLGVFARRREINIMKYIGATDWFIRWPFLIEGIVLGLLGALLSVGVLA
LMYGYTLDYVNSRLIVFNLLPLSDVIKDMALYFALLGSLIGAIGSGLSIKRFLNV

Sequences:

>Translated_295_residues
MLFRNFRYFIKEGFSNLARNRLMTVASVTSVMAALVILGMFLLIILNVNHMAYQVESQLELKAFLKDDLSGEQIQRIGEE
IKGIDGVSSVVFESKEQALQKFKKQLGEKSYLLEGLEKDNPLPQSYIVKVKDANLIKDIADEIKGINGVDKVSYGQDVVE
KLLGIIRIIRIVGLAIISILFVISIVIISNTIKLGVFARRREINIMKYIGATDWFIRWPFLIEGIVLGLLGALLSVGVLA
LMYGYTLDYVNSRLIVFNLLPLSDVIKDMALYFALLGSLIGAIGSGLSIKRFLNV
>Mature_295_residues
MLFRNFRYFIKEGFSNLARNRLMTVASVTSVMAALVILGMFLLIILNVNHMAYQVESQLELKAFLKDDLSGEQIQRIGEE
IKGIDGVSSVVFESKEQALQKFKKQLGEKSYLLEGLEKDNPLPQSYIVKVKDANLIKDIADEIKGINGVDKVSYGQDVVE
KLLGIIRIIRIVGLAIISILFVISIVIISNTIKLGVFARRREINIMKYIGATDWFIRWPFLIEGIVLGLLGALLSVGVLA
LMYGYTLDYVNSRLIVFNLLPLSDVIKDMALYFALLGSLIGAIGSGLSIKRFLNV

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789872, Length=231, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 32924; Mature: 32924

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFRNFRYFIKEGFSNLARNRLMTVASVTSVMAALVILGMFLLIILNVNHMAYQVESQLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LKAFLKDDLSGEQIQRIGEEIKGIDGVSSVVFESKEQALQKFKKQLGEKSYLLEGLEKDN
HHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
PLPQSYIVKVKDANLIKDIADEIKGINGVDKVSYGQDVVEKLLGIIRIIRIVGLAIISIL
CCCHHHEEEECCHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FVISIVIISNTIKLGVFARRREINIMKYIGATDWFIRWPFLIEGIVLGLLGALLSVGVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMYGYTLDYVNSRLIVFNLLPLSDVIKDMALYFALLGSLIGAIGSGLSIKRFLNV
HHHHHHHHHHCCEEHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
>Mature Secondary Structure
MLFRNFRYFIKEGFSNLARNRLMTVASVTSVMAALVILGMFLLIILNVNHMAYQVESQLE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
LKAFLKDDLSGEQIQRIGEEIKGIDGVSSVVFESKEQALQKFKKQLGEKSYLLEGLEKDN
HHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
PLPQSYIVKVKDANLIKDIADEIKGINGVDKVSYGQDVVEKLLGIIRIIRIVGLAIISIL
CCCHHHEEEECCHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FVISIVIISNTIKLGVFARRREINIMKYIGATDWFIRWPFLIEGIVLGLLGALLSVGVLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMYGYTLDYVNSRLIVFNLLPLSDVIKDMALYFALLGSLIGAIGSGLSIKRFLNV
HHHHHHHHHHCCEEHEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]