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The map label for this gene is His2.2 [C]

Identifier: 20808367

GI number: 20808367

Start: 1908771

End: 1909535

Strand: Reverse

Name: His2.2 [C]

Synonym: TTE1963

Alternate gene names: 20808367

Gene position: 1909535-1908771 (Counterclockwise)

Preceding gene: 20808368

Following gene: 20808366

Centisome position: 71.0

GC content: 41.83

Gene sequence:

>765_bases
TTGAAGGGGAGGATGAAATTGAGGCTGGTGCTAGATACTCACACCCACACCATCGCCAGTGGGCACGCATTTAGCACAAT
TATAGAAAATGCCAGGGAAGCCTTTAGAAAGGGGCTTCAGCTTATATGCATTACTGACCACGGACCGGAAATGCCAGGAG
GTCCGCATATATACTACTTTGGGAACTTAAAGGTGATACCTGAGAAAATAGAGGGGGTGGAGATACTAAAAGGAGTGGAA
GCCAATATAATGGACGAGGAAGGGAGGATAGACCTTCCTGAGAGGATTTTAAAAAAGCTGGATATTGTCATTGCAAGCCT
TCACGATGAGTGCTTTGAGCCAAGTGAGGATGTAGAGAGAAATACTAAAGCTTTAATAAATGCCATAAAAAATCCCTATG
TGGACATAATAGGACATCCGGGCAATCCCATATATCCCATTGATATTGAGAGAGTGCTTGAAGCTGCTAAAGAATACGGC
AAGTTTATAGAAATAAACAACAGCTCTTTTGTAACCTCTAGAAGAGGCAGTGAAAAAATATGCCCTATAATAGCCGGAAA
AGCTAAGGAAATGGGTGTTAGAGTGGCTGTAGGAAGTGATGCCCACATATGCTTTGACGTAGGACGGTTTGACGAGGCGA
TAAGGCTTTTAGAAGACATCAATATGCCAGAAGAGCTCGTATTAAATACTTCTGTAGATAAAGTAAAGCAATACTTACAA
GAAAAGAGGAAAAGAATTGGGGGAGGTCAAAACAGTTGGAATTAG

Upstream 100 bases:

>100_bases
CAATTATTGTAGAGGTTGCTGCAATGAACCATAGGCAGAAACAGATGGGCTACAACGCAGCCCATGAGCTCAATAAAAAA
CTTCTAAAGCAAATAGGAAA

Downstream 100 bases:

>100_bases
TAGTAAAAAATGATATAATTTTAATTGAGTGATGATAAATGTTATTAACTATAAAAAAGTTAAAGAGCTATATGATATAA
GCAGAATTATATTAATAACT

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKGRMKLRLVLDTHTHTIASGHAFSTIIENAREAFRKGLQLICITDHGPEMPGGPHIYYFGNLKVIPEKIEGVEILKGVE
ANIMDEEGRIDLPERILKKLDIVIASLHDECFEPSEDVERNTKALINAIKNPYVDIIGHPGNPIYPIDIERVLEAAKEYG
KFIEINNSSFVTSRRGSEKICPIIAGKAKEMGVRVAVGSDAHICFDVGRFDEAIRLLEDINMPEELVLNTSVDKVKQYLQ
EKRKRIGGGQNSWN

Sequences:

>Translated_254_residues
MKGRMKLRLVLDTHTHTIASGHAFSTIIENAREAFRKGLQLICITDHGPEMPGGPHIYYFGNLKVIPEKIEGVEILKGVE
ANIMDEEGRIDLPERILKKLDIVIASLHDECFEPSEDVERNTKALINAIKNPYVDIIGHPGNPIYPIDIERVLEAAKEYG
KFIEINNSSFVTSRRGSEKICPIIAGKAKEMGVRVAVGSDAHICFDVGRFDEAIRLLEDINMPEELVLNTSVDKVKQYLQ
EKRKRIGGGQNSWN
>Mature_254_residues
MKGRMKLRLVLDTHTHTIASGHAFSTIIENAREAFRKGLQLICITDHGPEMPGGPHIYYFGNLKVIPEKIEGVEILKGVE
ANIMDEEGRIDLPERILKKLDIVIASLHDECFEPSEDVERNTKALINAIKNPYVDIIGHPGNPIYPIDIERVLEAAKEYG
KFIEINNSSFVTSRRGSEKICPIIAGKAKEMGVRVAVGSDAHICFDVGRFDEAIRLLEDINMPEELVLNTSVDKVKQYLQ
EKRKRIGGGQNSWN

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP family

Homologues:

Organism=Escherichia coli, GI1787271, Length=232, Percent_Identity=42.2413793103448, Blast_Score=196, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1963_THETN (Q8R8N2)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623538.1
- ProteinModelPortal:   Q8R8N2
- SMR:   Q8R8N2
- GeneID:   997158
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1963
- NMPDR:   fig|273068.3.peg.1933
- HOGENOM:   HBG734021
- OMA:   HTIASTH
- ProtClustDB:   PRK09248
- BioCyc:   TTEN273068:TTE1963-MONOMER
- HAMAP:   MF_01561
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- SMART:   SM00481

Pfam domain/function: PF02811 PHP; SSF89550 PHP-like

EC number: NA

Molecular weight: Translated: 28485; Mature: 28485

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGRMKLRLVLDTHTHTIASGHAFSTIIENAREAFRKGLQLICITDHGPEMPGGPHIYYF
CCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEE
GNLKVIPEKIEGVEILKGVEANIMDEEGRIDLPERILKKLDIVIASLHDECFEPSEDVER
CCEEECCCHHCHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
NTKALINAIKNPYVDIIGHPGNPIYPIDIERVLEAAKEYGKFIEINNSSFVTSRRGSEKI
HHHHHHHHHCCCCEEEEECCCCCEEECCHHHHHHHHHHCCCEEEECCCEEEECCCCCCCC
CPIIAGKAKEMGVRVAVGSDAHICFDVGRFDEAIRLLEDINMPEELVLNTSVDKVKQYLQ
CCEECCCHHHCCEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCHHHEECCCHHHHHHHHH
EKRKRIGGGQNSWN
HHHHHCCCCCCCCC
>Mature Secondary Structure
MKGRMKLRLVLDTHTHTIASGHAFSTIIENAREAFRKGLQLICITDHGPEMPGGPHIYYF
CCCCEEEEEEEECCCEEEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEE
GNLKVIPEKIEGVEILKGVEANIMDEEGRIDLPERILKKLDIVIASLHDECFEPSEDVER
CCEEECCCHHCHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
NTKALINAIKNPYVDIIGHPGNPIYPIDIERVLEAAKEYGKFIEINNSSFVTSRRGSEKI
HHHHHHHHHCCCCEEEEECCCCCEEECCHHHHHHHHHHCCCEEEECCCEEEECCCCCCCC
CPIIAGKAKEMGVRVAVGSDAHICFDVGRFDEAIRLLEDINMPEELVLNTSVDKVKQYLQ
CCEECCCHHHCCEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCHHHEECCCHHHHHHHHH
EKRKRIGGGQNSWN
HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336