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The map label for this gene is GlpR [H]

Identifier: 20808349

GI number: 20808349

Start: 1891938

End: 1892693

Strand: Reverse

Name: GlpR [H]

Synonym: TTE1945

Alternate gene names: 20808349

Gene position: 1892693-1891938 (Counterclockwise)

Preceding gene: 20808350

Following gene: 20808348

Centisome position: 70.37

GC content: 37.43

Gene sequence:

>756_bases
ATGCTTGTTTCAACGAGGAGGGAAAAGATTAAGGAAATCATCTTAAAGAAAAAAGCTGTCAAGGTTTCAGAACTGTGTGA
AATATTCAAAGTCTCAGACGAAACAATAAGAAGGGATTTAGAGGAACTTGAGAGACAGGGGCTTATTGAGAGAAATTACG
GAGGAGCAGTATTGAAAGAAAATATAGTAGTTCCTCCCCTTGTCAAAAGGTTTAAAGAGCACATAGAGGAAAAGCAGAGA
ATTGCTGCAAAAGCTGTAACAGAGATTAAAGAGGGAAATGTCATATTCTTAGATGCAGGATCTACCACCTATCATATAGC
TAAGGCCATAAAGAGTTTAAAAGGCATAACAGTTATCACAAATGCTTTAAATGTTGCTACAGAACTCTCTACCAATCCAG
ACATTAACCTTTTTATCACTGGTGGCAAATTAAAACATGACAATCAGTCTATGGTAGGTTTCGAAACTGTAAACTGCATA
GGCAAGTACAACATAGATATATTGTTTTTAGGAACTGGCGGCATATCTGTAGAAAAAGGGCTTACCACTTCGGATATTTT
TGAAGCCGAAGCTAAAAAGGCCATGATAAGGTCTGCCAGCAGAGTGATTGTGGTTGCCGATAGTAGTAAATTTGGAAAAG
TTGCTATGGTGTCCTTTGCTACCTTTAACGATATTGAGAAGATAATAACTGCAGGGGAGGAAAACAGAGAAATAGTGAAG
CAGCTAACAGAGTATGTGAAGATTGAAATAGTGTAA

Upstream 100 bases:

>100_bases
AGGATTTTTTGGATTTGTGTAGAATTAATATAATGAAAGCAATAAAAATCCACAAATAATGTTAGGATTTTAACATCTTA
TAACATAGGAGAGGGTGTAG

Downstream 100 bases:

>100_bases
TTATGTTTGAAAGGAAGATGGAGATGATTAACAAGGTAGCTGAGTATCTTTCACGAGAAGGTTTTTATTTTTACGAAAAA
TCATTTAGAAAGTTTTCAGA

Product: sugar metabolism transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLVSTRREKIKEIILKKKAVKVSELCEIFKVSDETIRRDLEELERQGLIERNYGGAVLKENIVVPPLVKRFKEHIEEKQR
IAAKAVTEIKEGNVIFLDAGSTTYHIAKAIKSLKGITVITNALNVATELSTNPDINLFITGGKLKHDNQSMVGFETVNCI
GKYNIDILFLGTGGISVEKGLTTSDIFEAEAKKAMIRSASRVIVVADSSKFGKVAMVSFATFNDIEKIITAGEENREIVK
QLTEYVKIEIV

Sequences:

>Translated_251_residues
MLVSTRREKIKEIILKKKAVKVSELCEIFKVSDETIRRDLEELERQGLIERNYGGAVLKENIVVPPLVKRFKEHIEEKQR
IAAKAVTEIKEGNVIFLDAGSTTYHIAKAIKSLKGITVITNALNVATELSTNPDINLFITGGKLKHDNQSMVGFETVNCI
GKYNIDILFLGTGGISVEKGLTTSDIFEAEAKKAMIRSASRVIVVADSSKFGKVAMVSFATFNDIEKIITAGEENREIVK
QLTEYVKIEIV
>Mature_251_residues
MLVSTRREKIKEIILKKKAVKVSELCEIFKVSDETIRRDLEELERQGLIERNYGGAVLKENIVVPPLVKRFKEHIEEKQR
IAAKAVTEIKEGNVIFLDAGSTTYHIAKAIKSLKGITVITNALNVATELSTNPDINLFITGGKLKHDNQSMVGFETVNCI
GKYNIDILFLGTGGISVEKGLTTSDIFEAEAKKAMIRSASRVIVVADSSKFGKVAMVSFATFNDIEKIITAGEENREIVK
QLTEYVKIEIV

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=251, Percent_Identity=33.4661354581673, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788069, Length=232, Percent_Identity=37.5, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1789519, Length=229, Percent_Identity=34.4978165938865, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI87082344, Length=227, Percent_Identity=29.5154185022026, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789059, Length=227, Percent_Identity=33.920704845815, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789170, Length=230, Percent_Identity=30.8695652173913, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI226510968, Length=252, Percent_Identity=29.7619047619048, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790753, Length=232, Percent_Identity=28.8793103448276, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787540, Length=229, Percent_Identity=28.3842794759825, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790635, Length=247, Percent_Identity=26.7206477732794, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787063, Length=251, Percent_Identity=27.0916334661355, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27872; Mature: 27872

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSTRREKIKEIILKKKAVKVSELCEIFKVSDETIRRDLEELERQGLIERNYGGAVLKE
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NIVVPPLVKRFKEHIEEKQRIAAKAVTEIKEGNVIFLDAGSTTYHIAKAIKSLKGITVIT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCHHEEH
NALNVATELSTNPDINLFITGGKLKHDNQSMVGFETVNCIGKYNIDILFLGTGGISVEKG
HHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCHHHHHHEEECCEEEEEEECCCCEECCC
LTTSDIFEAEAKKAMIRSASRVIVVADSSKFGKVAMVSFATFNDIEKIITAGEENREIVK
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHH
QLTEYVKIEIV
HHHHHEEEEEC
>Mature Secondary Structure
MLVSTRREKIKEIILKKKAVKVSELCEIFKVSDETIRRDLEELERQGLIERNYGGAVLKE
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NIVVPPLVKRFKEHIEEKQRIAAKAVTEIKEGNVIFLDAGSTTYHIAKAIKSLKGITVIT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCHHEEH
NALNVATELSTNPDINLFITGGKLKHDNQSMVGFETVNCIGKYNIDILFLGTGGISVEKG
HHHHHHHHCCCCCCEEEEEECCEEECCCCCCCCHHHHHHEEECCEEEEEEECCCCEECCC
LTTSDIFEAEAKKAMIRSASRVIVVADSSKFGKVAMVSFATFNDIEKIITAGEENREIVK
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHHHH
QLTEYVKIEIV
HHHHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]