Click here to switch to the map view.

The map label for this gene is yicI [C]

Identifier: 20808338

GI number: 20808338

Start: 1875562

End: 1877979

Strand: Reverse

Name: yicI [C]

Synonym: TTE1934

Alternate gene names: 20808338

Gene position: 1877979-1875562 (Counterclockwise)

Preceding gene: 20808339

Following gene: 20808337

Centisome position: 69.83

GC content: 31.8

Gene sequence:

>2418_bases
ATGAATAGACTTTCACACAATCTTCATTTATTATCTCACAATAACAATACTTTTATTTTCAAAGCTGAAAATGAGGATAT
ACATGTGTATATATTCATACTTGAAGAGAACATAATTAGAATTTTAGTTCAAGATGGGGAGTTAAAAATACGAAAAACGT
GGTGGGTAGCACCCGGCATGAAGGATATTCCTTTGGAGGGGCGAGACAGGTTTGATTTAACCCCTTTTACTTTGCCGCCT
TATAAGTGGAATATAAAAGATAATAAATTTGAAGTATGTACTTCAGATTTATTACTTTTGGTAAATTTAAGAGATTTTAA
TTGCGAATGGTATGTGAAGAGAAATGACAGATGGTATAAAATTGCAGCGGATAGAAAAACACAAAGCTATAATTTTAAAA
ATTTACTTGGCGATGGTATTTATCATTATATGAGCATACTTGAAAACGAATCTTATTATGGGTTGGGGGAAAAAAGTGGA
GATATTGAAAGAAATGGAAGAAGGTTTAGGATGTTCAATATAGATGCATTAGGTTATGACGCAGAAAAAACAGATCCTTT
GTATAAGCATATTCCGTTTTATATTGTTCGAAATCACGATTATGGTGTTAGCTTTGGAATATTTTATGATGTTATGTCCC
AAGCAATATTTGATTTTGGTGTAGAGAAAGATGGTTACTATGGCCGAGATTACCGTTATTTTAAGGCAGAAGATGGAGAT
TTAGATTATTACTTTATTTTAGGACCCACACTAGAAAAGGTCGTTACATCCTTTACTTGGTTGACTGGTAAACCTATGTT
TCCCCCTAAATGGAGCATAGGGTATTCCGGTTCTTCAATGTCGTATACTGAAGTAGAGAACGCTCAAGAAGCACTTTTGG
AATTTCTTAATAAATGTGAAAAGTATGATATTCCAACAAGTTCGTTTCATCTTTCTTCCGGGTATACAAGTAAAGAAGGG
AAAAGATATGTATTTAATTGGAATAAAACAAAAATTCCATCTCCCCAGAAACTTACAAATGAGTTTCATGAAAAAGGTGT
AAAATTAATAGCAAATGTTAAACCTTTTTTATTAATTGACCATCCTTCTTATGAAGAATTAAAAGATAAGAAGATGTTTA
TACTTAGTAGAGATAGCATGGTACCACAGATAACTCAGTTATGGGATGATATGGGTTCATATATAGATTTTACGAATTTA
GAGGCTTTCAATTGGTGGAAAGAAAAAATAAAATATGCATTGTTAGATTACGGAATTGATGCAGTTTGGAATGATAATAA
TGAATTCGAAATTATGGATGGGAAAGCAATGGTTAATAATTTTGGCGAAAAAATAAATTTTGAAAAGGTAAGAGCTTTGT
TACCACTTCTAATGGCTAAGGCTTCTTTTGAGGCGATGGAAGAGTATAAAAGTTCGAAAAGACCTTTTTTAGTATCACGT
TCAGGTTGTCCTGGAATGCAAAGGTATTGCCAAACGTGGACAGGCGATAATTACACTGAATGGAAAACTTTAAGGTATAA
TCATTATATGGGTCTAGGATTAAGTTTATCAGGTGTATATAATTTTGGGCACGACGTGGGAGGATTTTATGGGCCTGCAC
CTGATCCAGAGTTATTTTTACGGTGGATTCAATACGGTATTTTTATGCCAAGATTTACTATTCACTCGTGGAATACTGAT
GGTACAGTTAATGAGCCATGGATGTATCCAGAGATTATAGAAGAGGTGAGGAATCTTATCAAATTTAGATACAAATTAAT
ACCGTACTTTTATCATCTATTTTATGAAGCCCATGAATTTTATCGTCCAATAATTAGGCCTGTTTTCTACGAGTTTGAAG
AAGATAAAGAAACTTTCAAATATAGTAAAGATGATTTAATGGTAGGACCTTTTATTCTGTTGACACCTGTGTTTGATAAA
GGAGTAAAAGAAAGGAATGTATATCTGCCTTTTACAAAGGATGGATGGGTAGAATACTTAAATCAAAAGGTTTATGAAGG
AGGACAATTTGTAAAAATAGAAGTTCCATTTTTACATACCAATTTTTTCATAAAAGGTGGTTCTATAATACCTATAAACG
ATAGTGAACACAAATTTGGAGAAATATCGGCGGAAAGGAGAGTACTTTGGATAGTTCCTCATATAAATGAGGGTAGAACA
TTTATAAGATTTTTTGAAGATGATGGTTTTTCTAAGAAGTATTTAGATGGAGAATATGCTTTTATAAATGTAGAACTGAA
TTCTTATAAAGAGAAAGTAGAAATAAAATTAGAAAAAGAAGGTAGATTTACATTGCCGTATAAGGATTTAAAATTACAAT
TGCCGCTTTTTGAAAAAAGAAATATAGCTGTATACTTTGCAAATGAAAAAATTTATGAAGGAAATGAAAAAGAAATTATT
CTGAAAATTCAAGAGTGA

Upstream 100 bases:

>100_bases
AGAGGAATAAAGTATAAAGGGAAATTTGTCGATGTGGTTGTGAAAAATAATTCTCTCAAAATATACTGTAATGGTATTGA
ATGTAAGGAGGAAGAATTGT

Downstream 100 bases:

>100_bases
GGTGAAGGAAGATGAATTTAAGAAATATTTTAAAGCTTCCTCCTATTCTTGAAGTAAAAAACGTTTTATGTGTACAACCT
CATCCAGATGATAATGAGAT

Product: alpha-glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 805; Mature: 805

Protein sequence:

>805_residues
MNRLSHNLHLLSHNNNTFIFKAENEDIHVYIFILEENIIRILVQDGELKIRKTWWVAPGMKDIPLEGRDRFDLTPFTLPP
YKWNIKDNKFEVCTSDLLLLVNLRDFNCEWYVKRNDRWYKIAADRKTQSYNFKNLLGDGIYHYMSILENESYYGLGEKSG
DIERNGRRFRMFNIDALGYDAEKTDPLYKHIPFYIVRNHDYGVSFGIFYDVMSQAIFDFGVEKDGYYGRDYRYFKAEDGD
LDYYFILGPTLEKVVTSFTWLTGKPMFPPKWSIGYSGSSMSYTEVENAQEALLEFLNKCEKYDIPTSSFHLSSGYTSKEG
KRYVFNWNKTKIPSPQKLTNEFHEKGVKLIANVKPFLLIDHPSYEELKDKKMFILSRDSMVPQITQLWDDMGSYIDFTNL
EAFNWWKEKIKYALLDYGIDAVWNDNNEFEIMDGKAMVNNFGEKINFEKVRALLPLLMAKASFEAMEEYKSSKRPFLVSR
SGCPGMQRYCQTWTGDNYTEWKTLRYNHYMGLGLSLSGVYNFGHDVGGFYGPAPDPELFLRWIQYGIFMPRFTIHSWNTD
GTVNEPWMYPEIIEEVRNLIKFRYKLIPYFYHLFYEAHEFYRPIIRPVFYEFEEDKETFKYSKDDLMVGPFILLTPVFDK
GVKERNVYLPFTKDGWVEYLNQKVYEGGQFVKIEVPFLHTNFFIKGGSIIPINDSEHKFGEISAERRVLWIVPHINEGRT
FIRFFEDDGFSKKYLDGEYAFINVELNSYKEKVEIKLEKEGRFTLPYKDLKLQLPLFEKRNIAVYFANEKIYEGNEKEII
LKIQE

Sequences:

>Translated_805_residues
MNRLSHNLHLLSHNNNTFIFKAENEDIHVYIFILEENIIRILVQDGELKIRKTWWVAPGMKDIPLEGRDRFDLTPFTLPP
YKWNIKDNKFEVCTSDLLLLVNLRDFNCEWYVKRNDRWYKIAADRKTQSYNFKNLLGDGIYHYMSILENESYYGLGEKSG
DIERNGRRFRMFNIDALGYDAEKTDPLYKHIPFYIVRNHDYGVSFGIFYDVMSQAIFDFGVEKDGYYGRDYRYFKAEDGD
LDYYFILGPTLEKVVTSFTWLTGKPMFPPKWSIGYSGSSMSYTEVENAQEALLEFLNKCEKYDIPTSSFHLSSGYTSKEG
KRYVFNWNKTKIPSPQKLTNEFHEKGVKLIANVKPFLLIDHPSYEELKDKKMFILSRDSMVPQITQLWDDMGSYIDFTNL
EAFNWWKEKIKYALLDYGIDAVWNDNNEFEIMDGKAMVNNFGEKINFEKVRALLPLLMAKASFEAMEEYKSSKRPFLVSR
SGCPGMQRYCQTWTGDNYTEWKTLRYNHYMGLGLSLSGVYNFGHDVGGFYGPAPDPELFLRWIQYGIFMPRFTIHSWNTD
GTVNEPWMYPEIIEEVRNLIKFRYKLIPYFYHLFYEAHEFYRPIIRPVFYEFEEDKETFKYSKDDLMVGPFILLTPVFDK
GVKERNVYLPFTKDGWVEYLNQKVYEGGQFVKIEVPFLHTNFFIKGGSIIPINDSEHKFGEISAERRVLWIVPHINEGRT
FIRFFEDDGFSKKYLDGEYAFINVELNSYKEKVEIKLEKEGRFTLPYKDLKLQLPLFEKRNIAVYFANEKIYEGNEKEII
LKIQE
>Mature_805_residues
MNRLSHNLHLLSHNNNTFIFKAENEDIHVYIFILEENIIRILVQDGELKIRKTWWVAPGMKDIPLEGRDRFDLTPFTLPP
YKWNIKDNKFEVCTSDLLLLVNLRDFNCEWYVKRNDRWYKIAADRKTQSYNFKNLLGDGIYHYMSILENESYYGLGEKSG
DIERNGRRFRMFNIDALGYDAEKTDPLYKHIPFYIVRNHDYGVSFGIFYDVMSQAIFDFGVEKDGYYGRDYRYFKAEDGD
LDYYFILGPTLEKVVTSFTWLTGKPMFPPKWSIGYSGSSMSYTEVENAQEALLEFLNKCEKYDIPTSSFHLSSGYTSKEG
KRYVFNWNKTKIPSPQKLTNEFHEKGVKLIANVKPFLLIDHPSYEELKDKKMFILSRDSMVPQITQLWDDMGSYIDFTNL
EAFNWWKEKIKYALLDYGIDAVWNDNNEFEIMDGKAMVNNFGEKINFEKVRALLPLLMAKASFEAMEEYKSSKRPFLVSR
SGCPGMQRYCQTWTGDNYTEWKTLRYNHYMGLGLSLSGVYNFGHDVGGFYGPAPDPELFLRWIQYGIFMPRFTIHSWNTD
GTVNEPWMYPEIIEEVRNLIKFRYKLIPYFYHLFYEAHEFYRPIIRPVFYEFEEDKETFKYSKDDLMVGPFILLTPVFDK
GVKERNVYLPFTKDGWVEYLNQKVYEGGQFVKIEVPFLHTNFFIKGGSIIPINDSEHKFGEISAERRVLWIVPHINEGRT
FIRFFEDDGFSKKYLDGEYAFINVELNSYKEKVEIKLEKEGRFTLPYKDLKLQLPLFEKRNIAVYFANEKIYEGNEKEII
LKIQE

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI66346737, Length=620, Percent_Identity=29.1935483870968, Blast_Score=260, Evalue=4e-69,
Organism=Homo sapiens, GI88900491, Length=648, Percent_Identity=27.1604938271605, Blast_Score=237, Evalue=3e-62,
Organism=Homo sapiens, GI38202257, Length=648, Percent_Identity=27.1604938271605, Blast_Score=236, Evalue=7e-62,
Organism=Homo sapiens, GI221316699, Length=669, Percent_Identity=24.9626307922272, Blast_Score=183, Evalue=5e-46,
Organism=Homo sapiens, GI157364974, Length=717, Percent_Identity=25.1046025104602, Blast_Score=177, Evalue=5e-44,
Organism=Homo sapiens, GI119393895, Length=663, Percent_Identity=25.4901960784314, Blast_Score=166, Evalue=9e-41,
Organism=Homo sapiens, GI119393893, Length=663, Percent_Identity=25.4901960784314, Blast_Score=166, Evalue=9e-41,
Organism=Homo sapiens, GI119393891, Length=663, Percent_Identity=25.4901960784314, Blast_Score=166, Evalue=9e-41,
Organism=Homo sapiens, GI310115361, Length=253, Percent_Identity=28.4584980237154, Blast_Score=113, Evalue=8e-25,
Organism=Escherichia coli, GI2367256, Length=568, Percent_Identity=23.7676056338028, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI2367323, Length=381, Percent_Identity=25.4593175853018, Blast_Score=120, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71991189, Length=632, Percent_Identity=28.6392405063291, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17560800, Length=631, Percent_Identity=27.892234548336, Blast_Score=231, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17560798, Length=631, Percent_Identity=27.892234548336, Blast_Score=231, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI71985706, Length=640, Percent_Identity=23.90625, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32563849, Length=650, Percent_Identity=23.8461538461538, Blast_Score=128, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6319706, Length=616, Percent_Identity=26.2987012987013, Blast_Score=193, Evalue=9e-50,
Organism=Drosophila melanogaster, GI24643749, Length=607, Percent_Identity=26.0296540362438, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24643753, Length=607, Percent_Identity=26.0296540362438, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24643751, Length=607, Percent_Identity=26.0296540362438, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24643746, Length=607, Percent_Identity=26.0296540362438, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI21357605, Length=607, Percent_Identity=26.0296540362438, Blast_Score=208, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 95438; Mature: 95438

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLSHNLHLLSHNNNTFIFKAENEDIHVYIFILEENIIRILVQDGELKIRKTWWVAPGM
CCCCCCEEEEEEECCCEEEEEECCCCEEEEEEEEECCEEEEEEECCCEEEEEEEEECCCC
KDIPLEGRDRFDLTPFTLPPYKWNIKDNKFEVCTSDLLLLVNLRDFNCEWYVKRNDRWYK
CCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEECCCEEEEEEEEECCEEEEEEECCEEEE
IAADRKTQSYNFKNLLGDGIYHYMSILENESYYGLGEKSGDIERNGRRFRMFNIDALGYD
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCEEEEEEEEEECCC
AEKTDPLYKHIPFYIVRNHDYGVSFGIFYDVMSQAIFDFGVEKDGYYGRDYRYFKAEDGD
CCCCCCHHHCCCEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCC
LDYYFILGPTLEKVVTSFTWLTGKPMFPPKWSIGYSGSSMSYTEVENAQEALLEFLNKCE
EEEEEEECCCHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KYDIPTSSFHLSSGYTSKEGKRYVFNWNKTKIPSPQKLTNEFHEKGVKLIANVKPFLLID
HCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEEE
HPSYEELKDKKMFILSRDSMVPQITQLWDDMGSYIDFTNLEAFNWWKEKIKYALLDYGID
CCCHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHCCCE
AVWNDNNEFEIMDGKAMVNNFGEKINFEKVRALLPLLMAKASFEAMEEYKSSKRPFLVSR
EEECCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
SGCPGMQRYCQTWTGDNYTEWKTLRYNHYMGLGLSLSGVYNFGHDVGGFYGPAPDPELFL
CCCCHHHHHHHHCCCCCCCCEEEEEEEEEEECCEEEEEHCCCCCCCCCCCCCCCCHHHHH
RWIQYGIFMPRFTIHSWNTDGTVNEPWMYPEIIEEVRNLIKFRYKLIPYFYHLFYEAHEF
HHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRPIIRPVFYEFEEDKETFKYSKDDLMVGPFILLTPVFDKGVKERNVYLPFTKDGWVEYL
HHHHHHHHHHHCCCCHHHHCCCCCCEEECCCEEEECHHHCCCCCCEEEEECCCCHHHHHH
NQKVYEGGQFVKIEVPFLHTNFFIKGGSIIPINDSEHKFGEISAERRVLWIVPHINEGRT
HHHHHCCCCEEEEEEEEEEEEEEEECCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCE
FIRFFEDDGFSKKYLDGEYAFINVELNSYKEKVEIKLEKEGRFTLPYKDLKLQLPLFEKR
EEEEEECCCCCCEECCCEEEEEEEEECCCCEEEEEEEECCCCEECCCCCCEEEECCCCCC
NIAVYFANEKIYEGNEKEIILKIQE
CEEEEEECCEEECCCCCEEEEEEEC
>Mature Secondary Structure
MNRLSHNLHLLSHNNNTFIFKAENEDIHVYIFILEENIIRILVQDGELKIRKTWWVAPGM
CCCCCCEEEEEEECCCEEEEEECCCCEEEEEEEEECCEEEEEEECCCEEEEEEEEECCCC
KDIPLEGRDRFDLTPFTLPPYKWNIKDNKFEVCTSDLLLLVNLRDFNCEWYVKRNDRWYK
CCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEECCCEEEEEEEEECCEEEEEEECCEEEE
IAADRKTQSYNFKNLLGDGIYHYMSILENESYYGLGEKSGDIERNGRRFRMFNIDALGYD
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCEEEEEEEEEECCC
AEKTDPLYKHIPFYIVRNHDYGVSFGIFYDVMSQAIFDFGVEKDGYYGRDYRYFKAEDGD
CCCCCCHHHCCCEEEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCC
LDYYFILGPTLEKVVTSFTWLTGKPMFPPKWSIGYSGSSMSYTEVENAQEALLEFLNKCE
EEEEEEECCCHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KYDIPTSSFHLSSGYTSKEGKRYVFNWNKTKIPSPQKLTNEFHEKGVKLIANVKPFLLID
HCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCEEEEE
HPSYEELKDKKMFILSRDSMVPQITQLWDDMGSYIDFTNLEAFNWWKEKIKYALLDYGID
CCCHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHHHHHCCCE
AVWNDNNEFEIMDGKAMVNNFGEKINFEKVRALLPLLMAKASFEAMEEYKSSKRPFLVSR
EEECCCCCEEEECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEC
SGCPGMQRYCQTWTGDNYTEWKTLRYNHYMGLGLSLSGVYNFGHDVGGFYGPAPDPELFL
CCCCHHHHHHHHCCCCCCCCEEEEEEEEEEECCEEEEEHCCCCCCCCCCCCCCCCHHHHH
RWIQYGIFMPRFTIHSWNTDGTVNEPWMYPEIIEEVRNLIKFRYKLIPYFYHLFYEAHEF
HHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRPIIRPVFYEFEEDKETFKYSKDDLMVGPFILLTPVFDKGVKERNVYLPFTKDGWVEYL
HHHHHHHHHHHCCCCHHHHCCCCCCEEECCCEEEECHHHCCCCCCEEEEECCCCHHHHHH
NQKVYEGGQFVKIEVPFLHTNFFIKGGSIIPINDSEHKFGEISAERRVLWIVPHINEGRT
HHHHHCCCCEEEEEEEEEEEEEEEECCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCE
FIRFFEDDGFSKKYLDGEYAFINVELNSYKEKVEIKLEKEGRFTLPYKDLKLQLPLFEKR
EEEEEECCCCCCEECCCEEEEEEEEECCCCEEEEEEEECCCCEECCCCCCEEEECCCCCC
NIAVYFANEKIYEGNEKEIILKIQE
CEEEEEECCEEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]