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The map label for this gene is Chb [H]

Identifier: 20808334

GI number: 20808334

Start: 1869006

End: 1870730

Strand: Reverse

Name: Chb [H]

Synonym: TTE1930

Alternate gene names: 20808334

Gene position: 1870730-1869006 (Counterclockwise)

Preceding gene: 20808335

Following gene: 20808333

Centisome position: 69.56

GC content: 35.07

Gene sequence:

>1725_bases
ATGGATAAAGTATTTATTGTTCCAGAACCTAAAAGATTTGTTTTTAATGGCAATTGGTTTTCATTTGATGGTTTTAATAA
CTTACCTGAATTTTTTAGAAAAGAGTTTAACATACCTCAAGGTAGTTGGGTTATTAAGAAGATAGATAGAGAAGGTACTG
GTGTAAAAATAAAAGAAAGAGAGGTAGAGATTTGGGGGGAGGAGAAAGTCTCCTATGCTACAATTATACAGATTGTGATG
CAGACAAAAAAGCGCCTTCCAGAAGTAGAGATAGAAGAGGAGTTTCATTTTCCATTTAGAGGGTATCATTTGGATATTGC
TAGAGGTGGAGTGCCCAATTTAGATACTTTTAAAAAGATTTTAAGATGGTTGTTTTTACTGAAATACAACTATTTTGGCA
TTTATTTCGAAGACCTTTTTCCATGGCAGAAATACCCTCAGATTGGAAAATTAAGAGGTAGATTGTCAAGAGAAGAATTG
GAAGAAATAATATCTTATGGGGAGAATTTAGGCATAGAAGTTTTTCCTTCTCTTGAGCTTTGCGGCCATATGGAAAATAT
ATTATCTCTTCCCGAATTTACAAGGTTTAGTGAATGGCACAGACCCCAGGAAGGTACCATTAACGTTTTTGATGAAGAGG
CGAGGGAGTTTACATATGACCTTTTAAGAGAAGTTGTAGAATTTTTCCCATCAGAGCACATTCACATTGGAGGAGATGAG
ACATGGGCTTTAGGTAGGGGTAAAAGTCTTGACAAAACAAATACTTTCAAGGGGCCAGAGCTTTTTGAACTTCATCACAG
AAATTTAATAAATATAGTAAGGGATAAAGGCAAAACCCCTATAGTTTGGGGAGATATGCTGACAGGGATGTATCTAAGAC
CTGATGAAAGAGAAAAGTGGAAAGTAGTGCTTGAAAGTGAAATATGGGATGATGTAATTATTGCTAACTGGGATTATACA
AACCTTTCTGAGAAGCACTTCCGTGAAAAAATAAATCTTTTTGGGAAAAGGAAGGAAAAGCAAATAGTATGTCCCGGTTT
TTCTAACTGGGGAAGATTTTATCCAAGTTTTGACATAGCCATAACTAATATAACTAACTTTTTGAAACCTGCGAAAGAAG
AAGGGGTAAAAGGTTTTTTAGTAACCTCATGGGGAGACGATGGAGCAGAAGCACTTTACAGCTTTTTAGATCCTTTGATA
CTTGCAAATATGGAAATTGCAGAAGGGAATGGAAATTGGGAGGAAAAGTGGATTGCACTTTCTGGAGAAAGGCATGAAGT
GCTAGAGGTAAGAAAATTATTTGGAAATGACCTCTTTTCAATGACAATTAAGCATGTATTTTTAGGAACACCTACCTTTA
GATATTATTCAGAGATTTTGAAAGATAATGTGCACAGGAGAGAAAAAAGTACAGGAGATTTGTGGCTGGACTATTACATG
GGATTCATAAAAAACCTTAAAGATACTGAAGCTCTTTTGAAGGAATATGAAAAAATGTTAGAAAAAGTTTACAATGTAAC
GCTACCAGAGGATTTAGAAATGATAAGGGATATGTTAAGAATTGGAATAAAAAGGCTAAGAGGCGAAGTCAATTTTTCTG
ATTTTGTTGAATTTGGAAATAGATATGCAAGGCTGTGGCTTTCTGAGAGGAAAAAAGAGAATTTAGAAGTTGTAATTGTA
AAAATTTATGGGGCTGCTGGAAGAGCTGACTTGAGGATTTTCTAA

Upstream 100 bases:

>100_bases
CTCCCTTATTTTTTTATGAAAAACTTTTTTGCCAAAACAGGATTTTTTAAAAAGATAAAGAACTTATTAAGGAATGAAGA
TTATGAGGAGGTAAGCTGTT

Downstream 100 bases:

>100_bases
AAATTTTTCACAAATTAGAAGGAATTTTTGAGTATGTGTCGAATATAATAAAAAAGATGTTAATTAAAATAATAAATAAA
CCTTTCACATAAAACAAAAT

Product: N-acetyl-beta-hexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MDKVFIVPEPKRFVFNGNWFSFDGFNNLPEFFRKEFNIPQGSWVIKKIDREGTGVKIKEREVEIWGEEKVSYATIIQIVM
QTKKRLPEVEIEEEFHFPFRGYHLDIARGGVPNLDTFKKILRWLFLLKYNYFGIYFEDLFPWQKYPQIGKLRGRLSREEL
EEIISYGENLGIEVFPSLELCGHMENILSLPEFTRFSEWHRPQEGTINVFDEEAREFTYDLLREVVEFFPSEHIHIGGDE
TWALGRGKSLDKTNTFKGPELFELHHRNLINIVRDKGKTPIVWGDMLTGMYLRPDEREKWKVVLESEIWDDVIIANWDYT
NLSEKHFREKINLFGKRKEKQIVCPGFSNWGRFYPSFDIAITNITNFLKPAKEEGVKGFLVTSWGDDGAEALYSFLDPLI
LANMEIAEGNGNWEEKWIALSGERHEVLEVRKLFGNDLFSMTIKHVFLGTPTFRYYSEILKDNVHRREKSTGDLWLDYYM
GFIKNLKDTEALLKEYEKMLEKVYNVTLPEDLEMIRDMLRIGIKRLRGEVNFSDFVEFGNRYARLWLSERKKENLEVVIV
KIYGAAGRADLRIF

Sequences:

>Translated_574_residues
MDKVFIVPEPKRFVFNGNWFSFDGFNNLPEFFRKEFNIPQGSWVIKKIDREGTGVKIKEREVEIWGEEKVSYATIIQIVM
QTKKRLPEVEIEEEFHFPFRGYHLDIARGGVPNLDTFKKILRWLFLLKYNYFGIYFEDLFPWQKYPQIGKLRGRLSREEL
EEIISYGENLGIEVFPSLELCGHMENILSLPEFTRFSEWHRPQEGTINVFDEEAREFTYDLLREVVEFFPSEHIHIGGDE
TWALGRGKSLDKTNTFKGPELFELHHRNLINIVRDKGKTPIVWGDMLTGMYLRPDEREKWKVVLESEIWDDVIIANWDYT
NLSEKHFREKINLFGKRKEKQIVCPGFSNWGRFYPSFDIAITNITNFLKPAKEEGVKGFLVTSWGDDGAEALYSFLDPLI
LANMEIAEGNGNWEEKWIALSGERHEVLEVRKLFGNDLFSMTIKHVFLGTPTFRYYSEILKDNVHRREKSTGDLWLDYYM
GFIKNLKDTEALLKEYEKMLEKVYNVTLPEDLEMIRDMLRIGIKRLRGEVNFSDFVEFGNRYARLWLSERKKENLEVVIV
KIYGAAGRADLRIF
>Mature_574_residues
MDKVFIVPEPKRFVFNGNWFSFDGFNNLPEFFRKEFNIPQGSWVIKKIDREGTGVKIKEREVEIWGEEKVSYATIIQIVM
QTKKRLPEVEIEEEFHFPFRGYHLDIARGGVPNLDTFKKILRWLFLLKYNYFGIYFEDLFPWQKYPQIGKLRGRLSREEL
EEIISYGENLGIEVFPSLELCGHMENILSLPEFTRFSEWHRPQEGTINVFDEEAREFTYDLLREVVEFFPSEHIHIGGDE
TWALGRGKSLDKTNTFKGPELFELHHRNLINIVRDKGKTPIVWGDMLTGMYLRPDEREKWKVVLESEIWDDVIIANWDYT
NLSEKHFREKINLFGKRKEKQIVCPGFSNWGRFYPSFDIAITNITNFLKPAKEEGVKGFLVTSWGDDGAEALYSFLDPLI
LANMEIAEGNGNWEEKWIALSGERHEVLEVRKLFGNDLFSMTIKHVFLGTPTFRYYSEILKDNVHRREKSTGDLWLDYYM
GFIKNLKDTEALLKEYEKMLEKVYNVTLPEDLEMIRDMLRIGIKRLRGEVNFSDFVEFGNRYARLWLSERKKENLEVVIV
KIYGAAGRADLRIF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI150456449, Length=231, Percent_Identity=27.7056277056277, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 67839; Mature: 67839

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVFIVPEPKRFVFNGNWFSFDGFNNLPEFFRKEFNIPQGSWVIKKIDREGTGVKIKER
CCCEEEEECCCEEEEECCEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEC
EVEIWGEEKVSYATIIQIVMQTKKRLPEVEIEEEFHFPFRGYHLDIARGGVPNLDTFKKI
EEEECCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEECCCCCCCHHHHHHH
LRWLFLLKYNYFGIYFEDLFPWQKYPQIGKLRGRLSREELEEIISYGENLGIEVFPSLEL
HHHHHHHHHHHCEEEHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCEEEECCHHH
CGHMENILSLPEFTRFSEWHRPQEGTINVFDEEAREFTYDLLREVVEFFPSEHIHIGGDE
HHHHHHHHCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
TWALGRGKSLDKTNTFKGPELFELHHRNLINIVRDKGKTPIVWGDMLTGMYLRPDEREKW
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCEECCCCCCHH
KVVLESEIWDDVIIANWDYTNLSEKHFREKINLFGKRKEKQIVCPGFSNWGRFYPSFDIA
EEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEE
ITNITNFLKPAKEEGVKGFLVTSWGDDGAEALYSFLDPLILANMEIAEGNGNWEEKWIAL
HHHHHHHHCCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEE
SGERHEVLEVRKLFGNDLFSMTIKHVFLGTPTFRYYSEILKDNVHRREKSTGDLWLDYYM
CCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
GFIKNLKDTEALLKEYEKMLEKVYNVTLPEDLEMIRDMLRIGIKRLRGEVNFSDFVEFGN
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RYARLWLSERKKENLEVVIVKIYGAAGRADLRIF
HHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEC
>Mature Secondary Structure
MDKVFIVPEPKRFVFNGNWFSFDGFNNLPEFFRKEFNIPQGSWVIKKIDREGTGVKIKER
CCCEEEEECCCEEEEECCEEEECCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEC
EVEIWGEEKVSYATIIQIVMQTKKRLPEVEIEEEFHFPFRGYHLDIARGGVPNLDTFKKI
EEEECCCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEEEECCCCCCCHHHHHHH
LRWLFLLKYNYFGIYFEDLFPWQKYPQIGKLRGRLSREELEEIISYGENLGIEVFPSLEL
HHHHHHHHHHHCEEEHHHCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCCCEEEECCHHH
CGHMENILSLPEFTRFSEWHRPQEGTINVFDEEAREFTYDLLREVVEFFPSEHIHIGGDE
HHHHHHHHCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
TWALGRGKSLDKTNTFKGPELFELHHRNLINIVRDKGKTPIVWGDMLTGMYLRPDEREKW
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCEECCCCCCHH
KVVLESEIWDDVIIANWDYTNLSEKHFREKINLFGKRKEKQIVCPGFSNWGRFYPSFDIA
EEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEE
ITNITNFLKPAKEEGVKGFLVTSWGDDGAEALYSFLDPLILANMEIAEGNGNWEEKWIAL
HHHHHHHHCCHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEE
SGERHEVLEVRKLFGNDLFSMTIKHVFLGTPTFRYYSEILKDNVHRREKSTGDLWLDYYM
CCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
GFIKNLKDTEALLKEYEKMLEKVYNVTLPEDLEMIRDMLRIGIKRLRGEVNFSDFVEFGN
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RYARLWLSERKKENLEVVIVKIYGAAGRADLRIF
HHHHHHHHHHCCCCCEEEEEEEECCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]