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The map label for this gene is fmdA [H]

Identifier: 20808324

GI number: 20808324

Start: 1857362

End: 1858261

Strand: Direct

Name: fmdA [H]

Synonym: TTE1919

Alternate gene names: 20808324

Gene position: 1857362-1858261 (Clockwise)

Preceding gene: 20808321

Following gene: 20808325

Centisome position: 69.06

GC content: 41.89

Gene sequence:

>900_bases
ATGAAGTACAGCCTTTCGGCAGACCATCACATATTTGCCTTTTCTAAGGAAAATAAGCCTGCCATTTCCGTGAAGAGCGG
AGATGAATTAGAAGTTGAAACAATGGACTGCTTCTCCAATCAAATTCAATCTAATGAGGACAAACTCGATGAGATGGACT
GGAACAGAGTAAACCCCGCCACAGGTCCAATTTTTGTGGAAGGCGCAAAAGAAGGAGATGTACTTAAAGTTAAAATCAAG
AAAATTGAAGTAGCAGAAAAAGGCGTTCTGGCAACAGGAAAAGGTCTAGGCGTATTGGGAAATTTAATGGAAGGCCTGTA
TTCCAAAGTAGTAGATATAAAGGATGGAAAGGTAATATTTAATGAAAAACTAGCTCTTCCTGTAAAGCCAATGATAGGAG
TAATAGGAGTTGCCCCAAAGGAAGGAAGCATTAACTGCGGAACGCCAGGGTCCCACGGTGGAAACATGGACACCACTTTA
ATAGCAGAAGGAGCAGAAGTCTACTTTCCTGTATTTGTAGAAGGAGCTTTGCTTGCTCTAGGGGACTTACACGCTTTAAT
GGGAGATGGAGAAGTAGGCGTTTCAGGCGTAGAAGTTGCTGGAAAAGTGCTTTTAGAAGTGGAAGTCATAAAGGGATTGA
ATCTCAAAAATCCTGTTGTGAAAACTGCTGAAGTAACAGCTACTATAGCTTCAGCCGAATCTTTAGACAAAGCAGTGGAA
ATAGCCGTACACGATATGGCAGAACTTTTTAAAAAGCACACAGACCTTTCTACCGAAGGAATAGCCACTCTCTTTAGCAT
AACAGGAAATGCACAAATATCACAGGTGGTTGACCCACTAAAAACAGCTCGTTTTAGCCTCCCCAACTGGATACTGGAAT
CCTACGGCATAAGATTCTGA

Upstream 100 bases:

>100_bases
AAAAATTAAAAGCTTAAAGTCAAAAGGAAAAGCACAATGTAGAAAAATTTTATTTTACAGGGTATAATATTGTTAATACA
ATTGTTGAGGGGGGATTTAA

Downstream 100 bases:

>100_bases
GGAGAGAAAGAAGATGATAGCAGAAGAAATAGTAAAACTAGAAAATGTTACTAAAAAGCTTGGAAGAAGGCTAACACTGG
AGGATATAAATTTTGAAGTA

Product: acetamidase/formamidase

Products: NA

Alternate protein names: Formamide amidohydrolase [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKYSLSADHHIFAFSKENKPAISVKSGDELEVETMDCFSNQIQSNEDKLDEMDWNRVNPATGPIFVEGAKEGDVLKVKIK
KIEVAEKGVLATGKGLGVLGNLMEGLYSKVVDIKDGKVIFNEKLALPVKPMIGVIGVAPKEGSINCGTPGSHGGNMDTTL
IAEGAEVYFPVFVEGALLALGDLHALMGDGEVGVSGVEVAGKVLLEVEVIKGLNLKNPVVKTAEVTATIASAESLDKAVE
IAVHDMAELFKKHTDLSTEGIATLFSITGNAQISQVVDPLKTARFSLPNWILESYGIRF

Sequences:

>Translated_299_residues
MKYSLSADHHIFAFSKENKPAISVKSGDELEVETMDCFSNQIQSNEDKLDEMDWNRVNPATGPIFVEGAKEGDVLKVKIK
KIEVAEKGVLATGKGLGVLGNLMEGLYSKVVDIKDGKVIFNEKLALPVKPMIGVIGVAPKEGSINCGTPGSHGGNMDTTL
IAEGAEVYFPVFVEGALLALGDLHALMGDGEVGVSGVEVAGKVLLEVEVIKGLNLKNPVVKTAEVTATIASAESLDKAVE
IAVHDMAELFKKHTDLSTEGIATLFSITGNAQISQVVDPLKTARFSLPNWILESYGIRF
>Mature_299_residues
MKYSLSADHHIFAFSKENKPAISVKSGDELEVETMDCFSNQIQSNEDKLDEMDWNRVNPATGPIFVEGAKEGDVLKVKIK
KIEVAEKGVLATGKGLGVLGNLMEGLYSKVVDIKDGKVIFNEKLALPVKPMIGVIGVAPKEGSINCGTPGSHGGNMDTTL
IAEGAEVYFPVFVEGALLALGDLHALMGDGEVGVSGVEVAGKVLLEVEVIKGLNLKNPVVKTAEVTATIASAESLDKAVE
IAVHDMAELFKKHTDLSTEGIATLFSITGNAQISQVVDPLKTARFSLPNWILESYGIRF

Specific function: Hydrolyzes formamide with the production of ammonia which can be used as a source of nitrogen for growth. Also acts, more slowly, on acetamide, propanamide and butanamide [H]

COG id: COG2421

COG function: function code C; Predicted acetamidase/formamidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetamidase/formamidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004304 [H]

Pfam domain/function: PF03069 FmdA_AmdA [H]

EC number: =3.5.1.49 [H]

Molecular weight: Translated: 31880; Mature: 31880

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYSLSADHHIFAFSKENKPAISVKSGDELEVETMDCFSNQIQSNEDKLDEMDWNRVNPA
CCCCCCCCCEEEEEECCCCCEEEECCCCCEEEHHHHHHHHHHCCCCHHHHHCCCCCCCCC
TGPIFVEGAKEGDVLKVKIKKIEVAEKGVLATGKGLGVLGNLMEGLYSKVVDIKDGKVIF
CCCEEEECCCCCCEEEEEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHEECCCCEEEE
NEKLALPVKPMIGVIGVAPKEGSINCGTPGSHGGNMDTTLIAEGAEVYFPVFVEGALLAL
CCCCCCCCCHHHHHEEECCCCCCEECCCCCCCCCCCCEEEEECCCEEEEEEHHHHHHHHH
GDLHALMGDGEVGVSGVEVAGKVLLEVEVIKGLNLKNPVVKTAEVTATIASAESLDKAVE
HHHHHHHCCCCCCCCHHHHHHHHEEEEEEHHCCCCCCCCEEHHHHEEEHHHHHHHHHHHH
IAVHDMAELFKKHTDLSTEGIATLFSITGNAQISQVVDPLKTARFSLPNWILESYGIRF
HHHHHHHHHHHHHCCCCCCHHEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCC
>Mature Secondary Structure
MKYSLSADHHIFAFSKENKPAISVKSGDELEVETMDCFSNQIQSNEDKLDEMDWNRVNPA
CCCCCCCCCEEEEEECCCCCEEEECCCCCEEEHHHHHHHHHHCCCCHHHHHCCCCCCCCC
TGPIFVEGAKEGDVLKVKIKKIEVAEKGVLATGKGLGVLGNLMEGLYSKVVDIKDGKVIF
CCCEEEECCCCCCEEEEEEEEEEECCCCEEECCCCHHHHHHHHHHHHHHHEECCCCEEEE
NEKLALPVKPMIGVIGVAPKEGSINCGTPGSHGGNMDTTLIAEGAEVYFPVFVEGALLAL
CCCCCCCCCHHHHHEEECCCCCCEECCCCCCCCCCCCEEEEECCCEEEEEEHHHHHHHHH
GDLHALMGDGEVGVSGVEVAGKVLLEVEVIKGLNLKNPVVKTAEVTATIASAESLDKAVE
HHHHHHHCCCCCCCCHHHHHHHHEEEEEEHHCCCCCCCCEEHHHHEEEHHHHHHHHHHHH
IAVHDMAELFKKHTDLSTEGIATLFSITGNAQISQVVDPLKTARFSLPNWILESYGIRF
HHHHHHHHHHHHHCCCCCCHHEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8841393 [H]