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The map label for this gene is DmpA2

Identifier: 20808213

GI number: 20808213

Start: 1741475

End: 1742449

Strand: Reverse

Name: DmpA2

Synonym: TTE1796

Alternate gene names: NA

Gene position: 1742449-1741475 (Counterclockwise)

Preceding gene: 20808214

Following gene: 20808212

Centisome position: 64.79

GC content: 42.87

Gene sequence:

>975_bases
ATGTCAATAAGAGAGATTGATATAAAGGAAATTGAAGGGATAAAAGTAGGCAATGCAGAAAATGTGGAAGCAGGCACAGG
CTGTACTGTAGTGATATGCGAGGAAGGGGCTACTCCAGGAGTGGATGTAAGAGGAGGAGCGCCGGGTACAAGAGAGACAG
ACCTTATACGGTCAGAAAATCTTGTAGAGAAGATTCATGCTGTAGTTTTAGCAGGGGGCTCTGCTTTTGGACTTGATGCG
GCTTCTGGGGTTATGAGGTATTTGGAAGAAAAGGGGATAGGGTTTGATACAGGTGTTTTAAAAATACCTATAGTTGCCAG
TGCTATACTTTTTGACCTTGCCGTTGGAAATCCTTATATAAGGCCGGATTTTGAAATGGGATACAAAGCCTGTGTAAATG
CTGAAAAAGGAGAATTTACCTATGGGAATAAAGGAGCGGGAACAGGAGCATCGGTAGGAAAATTTTTGGGGATTAAAAGG
GCTATGAAAAGCGGGCTAGGATGCTATGCACTTCAGGCAGGAGAGCTCAAGGTTGGAGCGGTGGTAGCGGTAAATGCACT
GGGAGATGTCTTTGACCCGGAGACCGGGGAAGTTATAGCGGGCTTGCTGGATGAAAAAGGAGAAAAGATAATAAGCACAG
AGGAAGCGATTATAGAGAATATTGGCCGAGAGAAAAGTGTTTTTCGCAATAATACTACGATAGGAGTTGTAATCACAAAT
GCAATGCTAAGTAAGGCAGAAGCTAATAAAGTGGCTTCAATGGCTCATGATGGATATGCAAGAGCTATAAAGCCTGTACA
TACCATGTTTGATGGTGACACAATTTTTGTCATGGCAACAGGGAAAGTGAAGGTAGACCCCACTTCAGTAGGCGTTTTAG
CAGTTAAAGCAGTGGAGAGGGCCATTGTAAGAGCTGTAAAAGAAGCAGAATCAGCTTATGGACTTAAGTCCTACAAGGAC
TTAAAAAAATTTTAA

Upstream 100 bases:

>100_bases
TGTTTCCTCACACCTATCATGTGGAGTTAGTAGGGCTTCTTGAAAAGAGTTAAGGAGAGAAGACAGTCATGTTAGTTAGT
TTGGAAATGGAGGTAGTTAG

Downstream 100 bases:

>100_bases
TTTTGTTGCTTTTTCTGGAAGGTTATAATAAAATTAAGTTGCAGAGAATTTTAAGGAGGCATTCCAGATGACGTGGATAA
TTTTGGGTATTATTGCGGTG

Product: L-aminopeptidase/D-esterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSIREIDIKEIEGIKVGNAENVEAGTGCTVVICEEGATPGVDVRGGAPGTRETDLIRSENLVEKIHAVVLAGGSAFGLDA
ASGVMRYLEEKGIGFDTGVLKIPIVASAILFDLAVGNPYIRPDFEMGYKACVNAEKGEFTYGNKGAGTGASVGKFLGIKR
AMKSGLGCYALQAGELKVGAVVAVNALGDVFDPETGEVIAGLLDEKGEKIISTEEAIIENIGREKSVFRNNTTIGVVITN
AMLSKAEANKVASMAHDGYARAIKPVHTMFDGDTIFVMATGKVKVDPTSVGVLAVKAVERAIVRAVKEAESAYGLKSYKD
LKKF

Sequences:

>Translated_324_residues
MSIREIDIKEIEGIKVGNAENVEAGTGCTVVICEEGATPGVDVRGGAPGTRETDLIRSENLVEKIHAVVLAGGSAFGLDA
ASGVMRYLEEKGIGFDTGVLKIPIVASAILFDLAVGNPYIRPDFEMGYKACVNAEKGEFTYGNKGAGTGASVGKFLGIKR
AMKSGLGCYALQAGELKVGAVVAVNALGDVFDPETGEVIAGLLDEKGEKIISTEEAIIENIGREKSVFRNNTTIGVVITN
AMLSKAEANKVASMAHDGYARAIKPVHTMFDGDTIFVMATGKVKVDPTSVGVLAVKAVERAIVRAVKEAESAYGLKSYKD
LKKF
>Mature_323_residues
SIREIDIKEIEGIKVGNAENVEAGTGCTVVICEEGATPGVDVRGGAPGTRETDLIRSENLVEKIHAVVLAGGSAFGLDAA
SGVMRYLEEKGIGFDTGVLKIPIVASAILFDLAVGNPYIRPDFEMGYKACVNAEKGEFTYGNKGAGTGASVGKFLGIKRA
MKSGLGCYALQAGELKVGAVVAVNALGDVFDPETGEVIAGLLDEKGEKIISTEEAIIENIGREKSVFRNNTTIGVVITNA
MLSKAEANKVASMAHDGYARAIKPVHTMFDGDTIFVMATGKVKVDPTSVGVLAVKAVERAIVRAVKEAESAYGLKSYKDL
KKF

Specific function: Unknown

COG id: COG3191

COG function: function code EQ; L-aminopeptidase/D-esterase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1167 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016117
- InterPro:   IPR005321 [H]

Pfam domain/function: PF03576 Peptidase_S58 [H]

EC number: NA

Molecular weight: Translated: 34009; Mature: 33877

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIREIDIKEIEGIKVGNAENVEAGTGCTVVICEEGATPGVDVRGGAPGTRETDLIRSEN
CCCCCCCHHHCCCEECCCCCCCCCCCCCEEEEECCCCCCCCEECCCCCCCCCHHHHHHHH
LVEKIHAVVLAGGSAFGLDAASGVMRYLEEKGIGFDTGVLKIPIVASAILFDLAVGNPYI
HHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHCCCCCC
RPDFEMGYKACVNAEKGEFTYGNKGAGTGASVGKFLGIKRAMKSGLGCYALQAGELKVGA
CCCHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEECC
VVAVNALGDVFDPETGEVIAGLLDEKGEKIISTEEAIIENIGREKSVFRNNTTIGVVITN
EEEEEHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCCEEEEEEEC
AMLSKAEANKVASMAHDGYARAIKPVHTMFDGDTIFVMATGKVKVDPTSVGVLAVKAVER
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECEEEECCCCHHHHHHHHHHH
AIVRAVKEAESAYGLKSYKDLKKF
HHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure 
SIREIDIKEIEGIKVGNAENVEAGTGCTVVICEEGATPGVDVRGGAPGTRETDLIRSEN
CCCCCCHHHCCCEECCCCCCCCCCCCCEEEEECCCCCCCCEECCCCCCCCCHHHHHHHH
LVEKIHAVVLAGGSAFGLDAASGVMRYLEEKGIGFDTGVLKIPIVASAILFDLAVGNPYI
HHHHHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHCCCCCC
RPDFEMGYKACVNAEKGEFTYGNKGAGTGASVGKFLGIKRAMKSGLGCYALQAGELKVGA
CCCHHHHHHHHCCCCCCCEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEECC
VVAVNALGDVFDPETGEVIAGLLDEKGEKIISTEEAIIENIGREKSVFRNNTTIGVVITN
EEEEEHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHCCCEEEEEEEC
AMLSKAEANKVASMAHDGYARAIKPVHTMFDGDTIFVMATGKVKVDPTSVGVLAVKAVER
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEEECEEEECCCCHHHHHHHHHHH
AIVRAVKEAESAYGLKSYKDLKKF
HHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]