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The map label for this gene is FabG4 [H]

Identifier: 20808207

GI number: 20808207

Start: 1736776

End: 1737582

Strand: Reverse

Name: FabG4 [H]

Synonym: TTE1790

Alternate gene names: 20808207

Gene position: 1737582-1736776 (Counterclockwise)

Preceding gene: 20808208

Following gene: 20808206

Centisome position: 64.61

GC content: 34.82

Gene sequence:

>807_bases
GTGGCAATTGCTTTTATAACAGGGGCTACGGATGGCATAGGAAGAGAAGTAGCTAAAAGGCTTGCTTTTCACGGCTATGA
TGTCATAATCCACGGGCGAAACGAACTTAAACTAGAAAAAGTTGCAGACGAAATAAGGGATTTGACAGGAAAAAGTGTTT
TTAAAATAAAAGCTGACTTTTCCTCTTTGAAAGATTTAAAGAAGTTGGTAAAAGAGATAAAAGATAATTTTTCAAAAGTA
GACCTGCTTTTAAATAATGCCGCTACTTTTGAAAAGGAAAGAAAAGTTACTGAAGAGGGTTTTGAGAGAACTTTTATGGT
CAATTATCTGGCACCTTTTTACCTCACGATTTCCTTGATTAATGAAGGGGTAGATATAAAATATGTGCTTAATGTAAGTT
CTATGGCTCATGCATCTTCAATTGAGTTTGAAGATTTGCAGCTTGAAAAAGGATACGACGGATACAAAGCTTATTCCCTT
TCTAAATTGTATATAACCTTATTTACCTATTATCTTGCAGAGATGTTGAAAGGCAAAATATATGTAAACTGCTTACATCC
AGGAGTTATAAATACAAAGCTTTTGATGGAAAATTGGGGAGCGATTGGGGCAAGCATAGAGGAAGGGGCTAAAAATGTAA
TTGATGCAATAAAATATATTGAGGCTCACAATGTTACGGGAGTGTATTTTGACAATGGCAAGCCCTCAAAGTCAAAACCT
ATTACTTACGACAGAGAAGTTCAGAGAAAATTGTGGGAAAAGACACTGAAGCTACTGAAGATAAATGAAAGAGATTTAAA
GTTTTAA

Upstream 100 bases:

>100_bases
TTTATCTTGGATTGCTTTTTTCTTAAGCAAATTAGAGATTAATTTGAATTGATAATTGTTATCTATTGTGGTATTATGGG
AGAAAAAGGAGGGATTTTTT

Downstream 100 bases:

>100_bases
AGACAAACGGTAAAATGTCAAGGGGGTAATTAAAAAATTTTTGAGGCATTTAAAGGGCAAAAAGACAAAAAAATACCCTT
CTTCCAACATGCCAATAAAT

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAIAFITGATDGIGREVAKRLAFHGYDVIIHGRNELKLEKVADEIRDLTGKSVFKIKADFSSLKDLKKLVKEIKDNFSKV
DLLLNNAATFEKERKVTEEGFERTFMVNYLAPFYLTISLINEGVDIKYVLNVSSMAHASSIEFEDLQLEKGYDGYKAYSL
SKLYITLFTYYLAEMLKGKIYVNCLHPGVINTKLLMENWGAIGASIEEGAKNVIDAIKYIEAHNVTGVYFDNGKPSKSKP
ITYDREVQRKLWEKTLKLLKINERDLKF

Sequences:

>Translated_268_residues
MAIAFITGATDGIGREVAKRLAFHGYDVIIHGRNELKLEKVADEIRDLTGKSVFKIKADFSSLKDLKKLVKEIKDNFSKV
DLLLNNAATFEKERKVTEEGFERTFMVNYLAPFYLTISLINEGVDIKYVLNVSSMAHASSIEFEDLQLEKGYDGYKAYSL
SKLYITLFTYYLAEMLKGKIYVNCLHPGVINTKLLMENWGAIGASIEEGAKNVIDAIKYIEAHNVTGVYFDNGKPSKSKP
ITYDREVQRKLWEKTLKLLKINERDLKF
>Mature_267_residues
AIAFITGATDGIGREVAKRLAFHGYDVIIHGRNELKLEKVADEIRDLTGKSVFKIKADFSSLKDLKKLVKEIKDNFSKVD
LLLNNAATFEKERKVTEEGFERTFMVNYLAPFYLTISLINEGVDIKYVLNVSSMAHASSIEFEDLQLEKGYDGYKAYSLS
KLYITLFTYYLAEMLKGKIYVNCLHPGVINTKLLMENWGAIGASIEEGAKNVIDAIKYIEAHNVTGVYFDNGKPSKSKPI
TYDREVQRKLWEKTLKLLKINERDLKF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI225579078, Length=285, Percent_Identity=32.9824561403509, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI193804850, Length=282, Percent_Identity=31.9148936170213, Blast_Score=123, Evalue=1e-28,
Organism=Homo sapiens, GI10190746, Length=281, Percent_Identity=30.2491103202847, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI186928839, Length=273, Percent_Identity=32.6007326007326, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI19923931, Length=253, Percent_Identity=32.4110671936759, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI166795268, Length=273, Percent_Identity=30.7692307692308, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI7706523, Length=282, Percent_Identity=27.3049645390071, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI146231950, Length=278, Percent_Identity=25.5395683453237, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI32483357, Length=203, Percent_Identity=29.5566502463054, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI19923817, Length=221, Percent_Identity=25.7918552036199, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI20149619, Length=242, Percent_Identity=28.5123966942149, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1787526, Length=198, Percent_Identity=29.2929292929293, Blast_Score=81, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI115533172, Length=267, Percent_Identity=31.0861423220974, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115533174, Length=265, Percent_Identity=31.3207547169811, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17558006, Length=282, Percent_Identity=25.531914893617, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17532791, Length=290, Percent_Identity=27.2413793103448, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI72001364, Length=296, Percent_Identity=24.6621621621622, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17532805, Length=282, Percent_Identity=25.531914893617, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=201, Percent_Identity=29.8507462686567, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17561402, Length=205, Percent_Identity=29.7560975609756, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=209, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322227, Length=206, Percent_Identity=25.7281553398058, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI22024069, Length=273, Percent_Identity=32.6007326007326, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19921754, Length=278, Percent_Identity=29.4964028776978, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24586328, Length=276, Percent_Identity=29.7101449275362, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573296, Length=282, Percent_Identity=31.2056737588652, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI45553409, Length=281, Percent_Identity=29.1814946619217, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24647948, Length=281, Percent_Identity=29.1814946619217, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24647946, Length=279, Percent_Identity=29.3906810035842, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI20129347, Length=282, Percent_Identity=31.2056737588652, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI161076371, Length=279, Percent_Identity=30.1075268817204, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI45554248, Length=198, Percent_Identity=34.3434343434343, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24640117, Length=198, Percent_Identity=34.3434343434343, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24656154, Length=284, Percent_Identity=31.3380281690141, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI19922628, Length=284, Percent_Identity=31.3380281690141, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24647931, Length=302, Percent_Identity=28.8079470198675, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24644339, Length=196, Percent_Identity=30.6122448979592, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571526, Length=196, Percent_Identity=30.1020408163265, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355319, Length=213, Percent_Identity=33.8028169014084, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357041, Length=196, Percent_Identity=30.1020408163265, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24643142, Length=205, Percent_Identity=30.2439024390244, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737361, Length=211, Percent_Identity=29.8578199052133, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30532; Mature: 30401

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIAFITGATDGIGREVAKRLAFHGYDVIIHGRNELKLEKVADEIRDLTGKSVFKIKADF
CEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCH
SSLKDLKKLVKEIKDNFSKVDLLLNNAATFEKERKVTEEGFERTFMVNYLAPFYLTISLI
HHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEGVDIKYVLNVSSMAHASSIEFEDLQLEKGYDGYKAYSLSKLYITLFTYYLAEMLKGKI
HCCCCEEEEEECHHHHHHCCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
YVNCLHPGVINTKLLMENWGAIGASIEEGAKNVIDAIKYIEAHNVTGVYFDNGKPSKSKP
EEEEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
ITYDREVQRKLWEKTLKLLKINERDLKF
CCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AIAFITGATDGIGREVAKRLAFHGYDVIIHGRNELKLEKVADEIRDLTGKSVFKIKADF
EEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCH
SSLKDLKKLVKEIKDNFSKVDLLLNNAATFEKERKVTEEGFERTFMVNYLAPFYLTISLI
HHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEGVDIKYVLNVSSMAHASSIEFEDLQLEKGYDGYKAYSLSKLYITLFTYYLAEMLKGKI
HCCCCEEEEEECHHHHHHCCCCHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCE
YVNCLHPGVINTKLLMENWGAIGASIEEGAKNVIDAIKYIEAHNVTGVYFDNGKPSKSKP
EEEEECCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCC
ITYDREVQRKLWEKTLKLLKINERDLKF
CCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]