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The map label for this gene is Fur4 [H]

Identifier: 20808186

GI number: 20808186

Start: 1714292

End: 1714714

Strand: Direct

Name: Fur4 [H]

Synonym: TTE1767

Alternate gene names: 20808186

Gene position: 1714292-1714714 (Clockwise)

Preceding gene: 20808169

Following gene: 20808198

Centisome position: 63.74

GC content: 38.77

Gene sequence:

>423_bases
ATGGAGGAAATTACTGCTCTTCTAAAGCAAAAAGGACTCAAAGTGACGCCTCAGCGCCTTGCAATTCTTAATTTCTTAAT
GCATACAAATGAGCATCCCACTGCTGAAACCATTTACAAAAAGCTAGTCTCTGATTTTCCTACAATGAGCCTTGCTACAG
TGTACAAGACTTTGGAAGTTTTAAAAAATACAGGGCTAATTCAGGAATTGAATGTAGGAGAAGGCAGTTTCAGATATGAC
GCAAAGACCACTCCCCATCCTCACATAGTCTGCCTTGGATGCGGCAAGGTAGAAGACTTGGATGAAAGCATTTTTAAAGA
TTTATTGGAAGAGGTAAAAAAGCACACGGATTACAAAGTTGTGGGACAAAAACTATATTTCTACGGTTACTGTCCCGCAT
GTCAGAAAAAAATGAACAATTAA

Upstream 100 bases:

>100_bases
TTCTAATAAAAACGATTGACATTATTAAAAAATAGGGATATAATAAAAACACGAAATATTAAGAGAGAAAGATTATTTTT
TATGGATTGGAGTGATAAAT

Downstream 100 bases:

>100_bases
AAAGCCCCACTTTAAAAAGTGGGACTTTTTTAATTTGCAGGCGATTCTTCAGTTGAAGTATCCGGTGGCGGTGAAGTATC
TGTGGGAGGAACAACTGGGC

Product: Fe2+/Zn2+ uptake regulation proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MEEITALLKQKGLKVTPQRLAILNFLMHTNEHPTAETIYKKLVSDFPTMSLATVYKTLEVLKNTGLIQELNVGEGSFRYD
AKTTPHPHIVCLGCGKVEDLDESIFKDLLEEVKKHTDYKVVGQKLYFYGYCPACQKKMNN

Sequences:

>Translated_140_residues
MEEITALLKQKGLKVTPQRLAILNFLMHTNEHPTAETIYKKLVSDFPTMSLATVYKTLEVLKNTGLIQELNVGEGSFRYD
AKTTPHPHIVCLGCGKVEDLDESIFKDLLEEVKKHTDYKVVGQKLYFYGYCPACQKKMNN
>Mature_140_residues
MEEITALLKQKGLKVTPQRLAILNFLMHTNEHPTAETIYKKLVSDFPTMSLATVYKTLEVLKNTGLIQELNVGEGSFRYD
AKTTPHPHIVCLGCGKVEDLDESIFKDLLEEVKKHTDYKVVGQKLYFYGYCPACQKKMNN

Specific function: Manganese-dependent repressor that controls a regulon of oxidative stress resistance and iron-storage proteins. May act as a hydrogen peroxide and organic hydroperoxide sensor [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=135, Percent_Identity=36.2962962962963, Blast_Score=77, Evalue=6e-16,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 15940; Mature: 15940

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEITALLKQKGLKVTPQRLAILNFLMHTNEHPTAETIYKKLVSDFPTMSLATVYKTLEV
CHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
LKNTGLIQELNVGEGSFRYDAKTTPHPHIVCLGCGKVEDLDESIFKDLLEEVKKHTDYKV
HHHCCCEEECCCCCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHH
VGQKLYFYGYCPACQKKMNN
HHHHHEEEEECHHHHHHCCC
>Mature Secondary Structure
MEEITALLKQKGLKVTPQRLAILNFLMHTNEHPTAETIYKKLVSDFPTMSLATVYKTLEV
CHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
LKNTGLIQELNVGEGSFRYDAKTTPHPHIVCLGCGKVEDLDESIFKDLLEEVKKHTDYKV
HHHCCCEEECCCCCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHH
VGQKLYFYGYCPACQKKMNN
HHHHHEEEEECHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA