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The map label for this gene is InfC

Identifier: 20808119

GI number: 20808119

Start: 1643682

End: 1644224

Strand: Reverse

Name: InfC

Synonym: TTE1693

Alternate gene names: 20808119

Gene position: 1644224-1643682 (Counterclockwise)

Preceding gene: 20808120

Following gene: 20808118

Centisome position: 61.14

GC content: 42.36

Gene sequence:

>543_bases
TTGATAATTTTTAGGAGGTGTGTATTTATTAACCATCGGGATTTTCAGGTAAATGAGCAAATTAGGGACAAAGAGGTAAG
GCTTATTGACCAGGATGGCAAGCAGATAGGGATAATGTCTGCCAAGGAAGCTTATAAGATTGCACAGGAGAGGCATTTGG
ACCTTGTGAAGATCGTTCCCAATGCCAATCCCCCTGTTTGTAAATTGATGGATTTTGGCAAGTACAGGTATGAGCTTAGC
AAGAGGGAAAAAGAAGCTAAGAAAAAACAAAAGATAATAAATGTGAAGGAGATAAGGATGTCCCCTAATATTGAAGACCA
TGACTTTGGAGTCAAATTGAAAAGTGCGATTAAGTTTTTAAAGGATGGGGACAAGGTGAAGGTGACTATAAGGTTTAGGG
GGAGAGAGGCGGCTCACACCTCCCTGGCAGAAGACCTTTTGAAGCGCTTTGCTGAGGAACTGAGGGAGTACGGCAATGTA
GAAAAGGCGCCGAGCATGGATGGTCGCAACATGATGATGGTAATAGCACCTAAAAAACAGTAG

Upstream 100 bases:

>100_bases
GCGCCCGCTTCTCACCTTTCGCCATAGGGCAGAAAGGTTTCTTCTTGAAAGTCAAAAGTAATATGGGCGAAGAAGCGGGT
GGATTATCCGCTTTTATTTT

Downstream 100 bases:

>100_bases
AAGAGGAGGATAATTATGGCAAAAATAAAGATGAAAACTCATAGGGGAGCAGCAAAGAGATTTAAGGTGTTAAAATCCGG
AAAAGTAAAGAGGATGAAAG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MIIFRRCVFINHRDFQVNEQIRDKEVRLIDQDGKQIGIMSAKEAYKIAQERHLDLVKIVPNANPPVCKLMDFGKYRYELS
KREKEAKKKQKIINVKEIRMSPNIEDHDFGVKLKSAIKFLKDGDKVKVTIRFRGREAAHTSLAEDLLKRFAEELREYGNV
EKAPSMDGRNMMMVIAPKKQ

Sequences:

>Translated_180_residues
MIIFRRCVFINHRDFQVNEQIRDKEVRLIDQDGKQIGIMSAKEAYKIAQERHLDLVKIVPNANPPVCKLMDFGKYRYELS
KREKEAKKKQKIINVKEIRMSPNIEDHDFGVKLKSAIKFLKDGDKVKVTIRFRGREAAHTSLAEDLLKRFAEELREYGNV
EKAPSMDGRNMMMVIAPKKQ
>Mature_180_residues
MIIFRRCVFINHRDFQVNEQIRDKEVRLIDQDGKQIGIMSAKEAYKIAQERHLDLVKIVPNANPPVCKLMDFGKYRYELS
KREKEAKKKQKIINVKEIRMSPNIEDHDFGVKLKSAIKFLKDGDKVKVTIRFRGREAAHTSLAEDLLKRFAEELREYGNV
EKAPSMDGRNMMMVIAPKKQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=171, Percent_Identity=50.2923976608187, Blast_Score=158, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_THETN (Q8R9C2)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623290.1
- ProteinModelPortal:   Q8R9C2
- GeneID:   996441
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1693
- NMPDR:   fig|273068.3.peg.1693
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- BioCyc:   TTEN273068:TTE1693-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 21061; Mature: 21061

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIFRRCVFINHRDFQVNEQIRDKEVRLIDQDGKQIGIMSAKEAYKIAQERHLDLVKIVP
CEEEEEEEEECCCCCEECCHHCCCCEEEEECCCCEEEEECHHHHHHHHHHHCCEEEEECC
NANPPVCKLMDFGKYRYELSKREKEAKKKQKIINVKEIRMSPNIEDHDFGVKLKSAIKFL
CCCCCEEHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCEEHHHHHHHH
KDGDKVKVTIRFRGREAAHTSLAEDLLKRFAEELREYGNVEKAPSMDGRNMMMVIAPKKQ
CCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCC
>Mature Secondary Structure
MIIFRRCVFINHRDFQVNEQIRDKEVRLIDQDGKQIGIMSAKEAYKIAQERHLDLVKIVP
CEEEEEEEEECCCCCEECCHHCCCCEEEEECCCCEEEEECHHHHHHHHHHHCCEEEEECC
NANPPVCKLMDFGKYRYELSKREKEAKKKQKIINVKEIRMSPNIEDHDFGVKLKSAIKFL
CCCCCEEHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCEEHHHHHHHH
KDGDKVKVTIRFRGREAAHTSLAEDLLKRFAEELREYGNVEKAPSMDGRNMMMVIAPKKQ
CCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336