Click here to switch to the map view.

The map label for this gene is queF

Identifier: 20807992

GI number: 20807992

Start: 1522332

End: 1522736

Strand: Reverse

Name: queF

Synonym: TTE1563

Alternate gene names: 20807992

Gene position: 1522736-1522332 (Counterclockwise)

Preceding gene: 20807993

Following gene: 20807991

Centisome position: 56.62

GC content: 31.36

Gene sequence:

>405_bases
TTGACAGATAAATATAAAGAGAGAAGATTTGACATTTACGGTTACGAAAAAATTGACAAAGAAGTTCTAGAATCTATTGA
ATATGAGTATCCTGAAAAAAATACTATCGTGGAGTATATTACCGATGAATTTTCTTCTGTTTGCCCTTGGACAGGATTAC
CTGACAATGCAAAACTTACTATAAGGTATATACCCCACAAAAAACTTGTAGAACTTAAATCCTTAAAATATTACCTTACA
TCTTATAGGAATGTAGGTATATTGCAAGAACATGCAATAAACAGAATTTTAGATGATTTGGTGGAATTCCTGCAGCCAAA
ATTTATGGAAATAATAGGCGAATTTCAGGAAAGAGGAGGAATAGCTACAAGAATTATAGCAAGGTATGAAAAAGAGGAGT
ATTAA

Upstream 100 bases:

>100_bases
TTTATTCCGACTTTCTTAAGCGTGGGAGTAGCGGAAACTGTACTTTTGGTAACTGGATATTTTTTGCTTTTCACAATTGA
AAAGAAAGGAGTTGTGAAAT

Downstream 100 bases:

>100_bases
ACTTAAAAGGCTGCCTAAAATTTTGTAGGCAGCTTTTTTATTCATTTTAGTTTTTCTTCAAAATGAGTTTACAGAGAACG
ATGAGGAAGCACTCAAATAC

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MTDKYKERRFDIYGYEKIDKEVLESIEYEYPEKNTIVEYITDEFSSVCPWTGLPDNAKLTIRYIPHKKLVELKSLKYYLT
SYRNVGILQEHAINRILDDLVEFLQPKFMEIIGEFQERGGIATRIIARYEKEEY

Sequences:

>Translated_134_residues
MTDKYKERRFDIYGYEKIDKEVLESIEYEYPEKNTIVEYITDEFSSVCPWTGLPDNAKLTIRYIPHKKLVELKSLKYYLT
SYRNVGILQEHAINRILDDLVEFLQPKFMEIIGEFQERGGIATRIIARYEKEEY
>Mature_133_residues
TDKYKERRFDIYGYEKIDKEVLESIEYEYPEKNTIVEYITDEFSSVCPWTGLPDNAKLTIRYIPHKKLVELKSLKYYLTS
YRNVGILQEHAINRILDDLVEFLQPKFMEIIGEFQERGGIATRIIARYEKEEY

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEF_THETN (Q8R9P3)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623163.1
- ProteinModelPortal:   Q8R9P3
- SMR:   Q8R9P3
- GeneID:   995665
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1563
- NMPDR:   fig|273068.3.peg.1510
- HOGENOM:   HBG294103
- OMA:   HEESANQ
- ProtClustDB:   PRK13258
- BioCyc:   TTEN273068:TTE1563-MONOMER
- BRENDA:   1.7.1.13
- GO:   GO:0005737
- HAMAP:   MF_00818
- InterPro:   IPR016856
- InterPro:   IPR020602
- PIRSF:   PIRSF027377
- TIGRFAMs:   TIGR03139

Pfam domain/function: PF01227 GTP_cyclohydroI

EC number: =1.7.1.13

Molecular weight: Translated: 16089; Mature: 15957

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKYKERRFDIYGYEKIDKEVLESIEYEYPEKNTIVEYITDEFSSVCPWTGLPDNAKLT
CCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
IRYIPHKKLVELKSLKYYLTSYRNVGILQEHAINRILDDLVEFLQPKFMEIIGEFQERGG
EEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IATRIIARYEKEEY
HHHHHHHHHHHCCC
>Mature Secondary Structure 
TDKYKERRFDIYGYEKIDKEVLESIEYEYPEKNTIVEYITDEFSSVCPWTGLPDNAKLT
CCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEE
IRYIPHKKLVELKSLKYYLTSYRNVGILQEHAINRILDDLVEFLQPKFMEIIGEFQERGG
EEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IATRIIARYEKEEY
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336