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The map label for this gene is Rpe2 [H]

Identifier: 20807941

GI number: 20807941

Start: 1463599

End: 1464249

Strand: Reverse

Name: Rpe2 [H]

Synonym: TTE1498

Alternate gene names: 20807941

Gene position: 1464249-1463599 (Counterclockwise)

Preceding gene: 20807942

Following gene: 20807940

Centisome position: 54.44

GC content: 40.55

Gene sequence:

>651_bases
TTGAAGATCGCACCTTCTATACTTTCAGCCGATTTTGCAAACCTTTTACAGGATGTAAAGGAAATAGAAGAAGATGCTGA
CCTTTTGCACATAGATGTGATGGACGGACATTTTGTGCCAAATATAACTATTGGCTCTGTGGTAGTAAAAGCGCTGAGGC
AGTACACCTCTTTGCCCTTTGATGTGCATCTGATGATTGAAAATCCAGACTTGTACATAGAGGATTTTGTAAAGGCCGGA
GCAGACATAATCACGGTCCATCAAGAGGCTTGTGTGCATTTGCACAGGACAATACAGAGGATAAAAGGCCATGAAGTAAA
AGCAGGTGTTGCACTAAATCCTGCCACACCTCTTGAGACTTTGAAGTACATTCTTGAATACGTGGACCTGGTGCTTGTGA
TGACTGTAAACCCTGGATTTGGGGGTCAAAAGTTTATAGATTCAATGCTTAAAAAGATTAAAGAGTTGGACGAGATGAGA
AAAGAAATGAATTTAAGTTTTGAAATTGAGGTTGACGGAGGGATAAATATAAAAAACATAAAACAAGTCGTGGAAGCAGG
CGCAGATATAATTGTTGCAGGGTCCGCCATTTTTGAGTCACCAGACCCTTCTTCTACTATAAAAGAGTTCAGAGAGGCTG
TAGGAACATGA

Upstream 100 bases:

>100_bases
CTGAAGCAGTGGATGAGGGCATTATAGACAGGCAAAGGTATATAAGTTATTTGACTCTTTTAAGGGAGGTAAAAGAGAAG
GAGAAGAGGAGGTATAAAAA

Downstream 100 bases:

>100_bases
AAGTGCTGATCATTTCTAATGGAGAAATAAAAGATTATGGATTTTACAAAAACATTGTAGAAGAAGTAGATATGGTCATA
TGCGCTGACGGAGGAGCTAA

Product: Pentose-5-phosphate-3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MKIAPSILSADFANLLQDVKEIEEDADLLHIDVMDGHFVPNITIGSVVVKALRQYTSLPFDVHLMIENPDLYIEDFVKAG
ADIITVHQEACVHLHRTIQRIKGHEVKAGVALNPATPLETLKYILEYVDLVLVMTVNPGFGGQKFIDSMLKKIKELDEMR
KEMNLSFEIEVDGGINIKNIKQVVEAGADIIVAGSAIFESPDPSSTIKEFREAVGT

Sequences:

>Translated_216_residues
MKIAPSILSADFANLLQDVKEIEEDADLLHIDVMDGHFVPNITIGSVVVKALRQYTSLPFDVHLMIENPDLYIEDFVKAG
ADIITVHQEACVHLHRTIQRIKGHEVKAGVALNPATPLETLKYILEYVDLVLVMTVNPGFGGQKFIDSMLKKIKELDEMR
KEMNLSFEIEVDGGINIKNIKQVVEAGADIIVAGSAIFESPDPSSTIKEFREAVGT
>Mature_216_residues
MKIAPSILSADFANLLQDVKEIEEDADLLHIDVMDGHFVPNITIGSVVVKALRQYTSLPFDVHLMIENPDLYIEDFVKAG
ADIITVHQEACVHLHRTIQRIKGHEVKAGVALNPATPLETLKYILEYVDLVLVMTVNPGFGGQKFIDSMLKKIKELDEMR
KEMNLSFEIEVDGGINIKNIKQVVEAGADIIVAGSAIFESPDPSSTIKEFREAVGT

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=213, Percent_Identity=44.131455399061, Blast_Score=172, Evalue=1e-43,
Organism=Homo sapiens, GI219879828, Length=213, Percent_Identity=42.2535211267606, Blast_Score=161, Evalue=4e-40,
Organism=Homo sapiens, GI24307923, Length=168, Percent_Identity=34.5238095238095, Blast_Score=104, Evalue=6e-23,
Organism=Escherichia coli, GI1789788, Length=212, Percent_Identity=50.9433962264151, Blast_Score=217, Evalue=4e-58,
Organism=Escherichia coli, GI1790523, Length=197, Percent_Identity=42.1319796954315, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1790754, Length=211, Percent_Identity=31.7535545023697, Blast_Score=107, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17552948, Length=218, Percent_Identity=41.743119266055, Blast_Score=166, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6322341, Length=226, Percent_Identity=42.9203539823009, Blast_Score=184, Evalue=7e-48,
Organism=Drosophila melanogaster, GI24586301, Length=215, Percent_Identity=42.7906976744186, Blast_Score=174, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23896; Mature: 23896

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAPSILSADFANLLQDVKEIEEDADLLHIDVMDGHFVPNITIGSVVVKALRQYTSLPF
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCE
DVHLMIENPDLYIEDFVKAGADIITVHQEACVHLHRTIQRIKGHEVKAGVALNPATPLET
EEEEEEECCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEECCEEECCCCHHHH
LKYILEYVDLVLVMTVNPGFGGQKFIDSMLKKIKELDEMRKEMNLSFEIEVDGGINIKNI
HHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
KQVVEAGADIIVAGSAIFESPDPSSTIKEFREAVGT
HHHHHCCCCEEEECCHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKIAPSILSADFANLLQDVKEIEEDADLLHIDVMDGHFVPNITIGSVVVKALRQYTSLPF
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCE
DVHLMIENPDLYIEDFVKAGADIITVHQEACVHLHRTIQRIKGHEVKAGVALNPATPLET
EEEEEEECCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEECCEEECCCCHHHH
LKYILEYVDLVLVMTVNPGFGGQKFIDSMLKKIKELDEMRKEMNLSFEIEVDGGINIKNI
HHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
KQVVEAGADIIVAGSAIFESPDPSSTIKEFREAVGT
HHHHHCCCCEEEECCHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]