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The map label for this gene is RecG [H]

Identifier: 20807935

GI number: 20807935

Start: 1458346

End: 1460394

Strand: Reverse

Name: RecG [H]

Synonym: TTE1492

Alternate gene names: 20807935

Gene position: 1460394-1458346 (Counterclockwise)

Preceding gene: 20807936

Following gene: 20807934

Centisome position: 54.3

GC content: 39.09

Gene sequence:

>2049_bases
ATGTCCTTGGATTTAGATATACAGTACGTCAAAGGTGTGGGACCTAAAAGGGCAAAACTTTTTAAGAAACTGGGCATAGA
TATGGTAAAGGACTTAATATTTTACTTTCCTAGGGACTATGAAGACAGAAGTGAGATAGTGAAAATTGAAGATTTGATAG
TGGGGGAAAAGCAGACTTTTAAGGCCTATATTGCGGGAAGTGCAAGAGAAGTAAAAACTTCCCGCGTTGTCATTACAAAA
ATTCCCGTAAAAGATGGAACAGGGGCTGTAGAGCTTGTGTGGTACAATCAGCCCTATATGAAAAATAACTTCAAAATCGG
GGAAGAGTATATCATAAGCGGAAAATTGCAGTTTAAATACGGCCAGCTTGTAGTGGAAAACCCTGTATTAGAAAAGTCAG
AAGAGGATTTGAATTTAAATACTGGGAGAATTGTGCCTGTCTACGGGTTAACTGAGGGTCTTACACAGAACATTTTGAGA
AAAGTTATATTTAACGCATTAAGCGAATACCTTGATGAGGTAGAAGAATTTTTTGAGGAAGAGTTTTTACGTGAAAAAGG
GCTCATGAATTTGAAAGAGGCTTTATTGAACATTCACTTTCCGAAGGATGAGGAAAAGCTTGCAAGGGCAAAATACAGGT
TGAAGTATCAGGAATTGTTCTTATTGCAGTTGGCACTATTTTTGGTGAAAAAGTCAGTTAAAGAAAAGAGAGGGATAAGG
TTTAGAAAGGTAGACATAAAGCCTTTTGTTTCAAACCTCCCGTTTAAGCTTACTTCTGCTCAAATGAAGGTTTTGAAAGA
GATAATACTGGACATGGCCTCTGACAAAGTGATGAATAGACTTATACAGGGAGATGTGGGGTCAGGTAAGACAATAGTGG
CTGCTTTTGCCATGTACATTGCAGCAAAAAACGGGTATCAGGTAGCCATGATGGCTCCAACAGAAATACTAGCAAAGCAG
CATTACAAGACTCTCGAAGAAATTTTTAAAGGAACAGATATCCGCATAGGCCTTTTGTCAGGCAGTCTTTCTCCTTCTGG
GAGGAAAGAGGTGCTGGAGAAGATTGAAAAGGGAGAGTACGATGTAGTAGTAGGTACTCATGCCCTCATAGAAGAAGACG
TTTCTTTTAAAAATTTAGGCCTTTGCATAACAGATGAACAGCACCGATTTGGAGTGAGGCAGAGGGCGCTTTTGGCTCAA
AAGGGAGAAAATCCAGACGTTTTAGTTATGACGGCTACTCCTATTCCACGAACTTTAGCTTTAATCTTATACGGAGATTT
AGATATATCAATAATTGACCAGTTGCCACCTGGCAGAAAAAGAGTAAAAACTTACGTAATACCTTCGTCCATGAGAAAGA
AGGCCTATGAATTTGCGATTAAAGAAGTAAAAAAAGGGAGACAAGTTTACGTTGTATGCCCTTTGATTGAAGAATCGGAT
AAAATAAAAGCGGCTTCTGCCGAAATAGTATATAGAGAAATTTACAAAGACGCTTTTAAAGAAGCAAGAGTTGGACTTTT
ACACGGAAAAATGTCGGACAGCGACAAAGAGAGGATTATGGAGGCATTTGTCAGAGGAGAGATTGACATACTTGTTTCAA
CGACAGTCATAGAAGTAGGGGTGAATGTGCCTAATGCTACGGTGATGATTGTGGAAAATGCAGAGAGATTTGGACTTGCT
CAGCTTCATCAGTTGAGAGGAAGGGTTGGGAGGTCTGAATTTCAGTCCTATTGCATTTTGATAAACTATTCTCCCTCTGA
AACTGCGAAAAAAAGGCTGGAGGTCTTAGCTAGGACTTCTGATGGATTTAAAATCGCAGAAAGGGACCTGGAGATAAGGG
GGCCAGGTGAATTTTTAGGCGAAAAGCAACACGGCCTTCCTGAGTTTAAAATCGCTAACCTTTTTGAGGATATCGATATA
CTAAAAAGGGTACAAAAGGATGTGGAAAGCCTTCTTGAAGAAGACCCTAAACTTGAAAGGCATCCTAAATTGAGGCAAGT
TCTCATATCAGAATTTTATGACAAAGTAAAGGATATAATATTAAATTAA

Upstream 100 bases:

>100_bases
CTTAGAAATTTGATTTCTAAAGATGTAGAAGTAGAAATCCATTACGGGGGTCAGCCTCTTTATTACTATGTCATATCGAT
TGAATAAAAGGTGAAAAGGC

Downstream 100 bases:

>100_bases
CAGAAAAGGAGAATAGTGGTATGGAAAAGATAGCAATTGTCACTGACAGCTTATCCGATATACCTGAAGATTTAATAAAA
ACTTACGGGATCTTCGTGGT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 682; Mature: 681

Protein sequence:

>682_residues
MSLDLDIQYVKGVGPKRAKLFKKLGIDMVKDLIFYFPRDYEDRSEIVKIEDLIVGEKQTFKAYIAGSAREVKTSRVVITK
IPVKDGTGAVELVWYNQPYMKNNFKIGEEYIISGKLQFKYGQLVVENPVLEKSEEDLNLNTGRIVPVYGLTEGLTQNILR
KVIFNALSEYLDEVEEFFEEEFLREKGLMNLKEALLNIHFPKDEEKLARAKYRLKYQELFLLQLALFLVKKSVKEKRGIR
FRKVDIKPFVSNLPFKLTSAQMKVLKEIILDMASDKVMNRLIQGDVGSGKTIVAAFAMYIAAKNGYQVAMMAPTEILAKQ
HYKTLEEIFKGTDIRIGLLSGSLSPSGRKEVLEKIEKGEYDVVVGTHALIEEDVSFKNLGLCITDEQHRFGVRQRALLAQ
KGENPDVLVMTATPIPRTLALILYGDLDISIIDQLPPGRKRVKTYVIPSSMRKKAYEFAIKEVKKGRQVYVVCPLIEESD
KIKAASAEIVYREIYKDAFKEARVGLLHGKMSDSDKERIMEAFVRGEIDILVSTTVIEVGVNVPNATVMIVENAERFGLA
QLHQLRGRVGRSEFQSYCILINYSPSETAKKRLEVLARTSDGFKIAERDLEIRGPGEFLGEKQHGLPEFKIANLFEDIDI
LKRVQKDVESLLEEDPKLERHPKLRQVLISEFYDKVKDIILN

Sequences:

>Translated_682_residues
MSLDLDIQYVKGVGPKRAKLFKKLGIDMVKDLIFYFPRDYEDRSEIVKIEDLIVGEKQTFKAYIAGSAREVKTSRVVITK
IPVKDGTGAVELVWYNQPYMKNNFKIGEEYIISGKLQFKYGQLVVENPVLEKSEEDLNLNTGRIVPVYGLTEGLTQNILR
KVIFNALSEYLDEVEEFFEEEFLREKGLMNLKEALLNIHFPKDEEKLARAKYRLKYQELFLLQLALFLVKKSVKEKRGIR
FRKVDIKPFVSNLPFKLTSAQMKVLKEIILDMASDKVMNRLIQGDVGSGKTIVAAFAMYIAAKNGYQVAMMAPTEILAKQ
HYKTLEEIFKGTDIRIGLLSGSLSPSGRKEVLEKIEKGEYDVVVGTHALIEEDVSFKNLGLCITDEQHRFGVRQRALLAQ
KGENPDVLVMTATPIPRTLALILYGDLDISIIDQLPPGRKRVKTYVIPSSMRKKAYEFAIKEVKKGRQVYVVCPLIEESD
KIKAASAEIVYREIYKDAFKEARVGLLHGKMSDSDKERIMEAFVRGEIDILVSTTVIEVGVNVPNATVMIVENAERFGLA
QLHQLRGRVGRSEFQSYCILINYSPSETAKKRLEVLARTSDGFKIAERDLEIRGPGEFLGEKQHGLPEFKIANLFEDIDI
LKRVQKDVESLLEEDPKLERHPKLRQVLISEFYDKVKDIILN
>Mature_681_residues
SLDLDIQYVKGVGPKRAKLFKKLGIDMVKDLIFYFPRDYEDRSEIVKIEDLIVGEKQTFKAYIAGSAREVKTSRVVITKI
PVKDGTGAVELVWYNQPYMKNNFKIGEEYIISGKLQFKYGQLVVENPVLEKSEEDLNLNTGRIVPVYGLTEGLTQNILRK
VIFNALSEYLDEVEEFFEEEFLREKGLMNLKEALLNIHFPKDEEKLARAKYRLKYQELFLLQLALFLVKKSVKEKRGIRF
RKVDIKPFVSNLPFKLTSAQMKVLKEIILDMASDKVMNRLIQGDVGSGKTIVAAFAMYIAAKNGYQVAMMAPTEILAKQH
YKTLEEIFKGTDIRIGLLSGSLSPSGRKEVLEKIEKGEYDVVVGTHALIEEDVSFKNLGLCITDEQHRFGVRQRALLAQK
GENPDVLVMTATPIPRTLALILYGDLDISIIDQLPPGRKRVKTYVIPSSMRKKAYEFAIKEVKKGRQVYVVCPLIEESDK
IKAASAEIVYREIYKDAFKEARVGLLHGKMSDSDKERIMEAFVRGEIDILVSTTVIEVGVNVPNATVMIVENAERFGLAQ
LHQLRGRVGRSEFQSYCILINYSPSETAKKRLEVLARTSDGFKIAERDLEIRGPGEFLGEKQHGLPEFKIANLFEDIDIL
KRVQKDVESLLEEDPKLERHPKLRQVLISEFYDKVKDIILN

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=688, Percent_Identity=40.2616279069767, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1787357, Length=404, Percent_Identity=40.3465346534653, Blast_Score=298, Evalue=8e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77748; Mature: 77617

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLDLDIQYVKGVGPKRAKLFKKLGIDMVKDLIFYFPRDYEDRSEIVKIEDLIVGEKQTF
CCCCCEEHHHCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHEEEHHHHHCCCHHHH
KAYIAGSAREVKTSRVVITKIPVKDGTGAVELVWYNQPYMKNNFKIGEEYIISGKLQFKY
HHHCCCCCHHEECCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECEEEEEE
GQLVVENPVLEKSEEDLNLNTGRIVPVYGLTEGLTQNILRKVIFNALSEYLDEVEEFFEE
CCEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFLREKGLMNLKEALLNIHFPKDEEKLARAKYRLKYQELFLLQLALFLVKKSVKEKRGIR
HHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
FRKVDIKPFVSNLPFKLTSAQMKVLKEIILDMASDKVMNRLIQGDVGSGKTIVAAFAMYI
EEEEECCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AAKNGYQVAMMAPTEILAKQHYKTLEEIFKGTDIRIGLLSGSLSPSGRKEVLEKIEKGEY
HCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCE
DVVVGTHALIEEDVSFKNLGLCITDEQHRFGVRQRALLAQKGENPDVLVMTATPIPRTLA
EEEECCHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHEE
LILYGDLDISIIDQLPPGRKRVKTYVIPSSMRKKAYEFAIKEVKKGRQVYVVCPLIEESD
EEEECCCCEEEECCCCCCHHHEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCC
KIKAASAEIVYREIYKDAFKEARVGLLHGKMSDSDKERIMEAFVRGEIDILVSTTVIEVG
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCEEEEEEEEEEEEE
VNVPNATVMIVENAERFGLAQLHQLRGRVGRSEFQSYCILINYSPSETAKKRLEVLARTS
CCCCCEEEEEEECCCHHHHHHHHHHHHHCCHHHHCCEEEEEEECCCHHHHHHHHHHHCCC
DGFKIAERDLEIRGPGEFLGEKQHGLPEFKIANLFEDIDILKRVQKDVESLLEEDPKLER
CCCEEECCCEEECCCHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HPKLRQVLISEFYDKVKDIILN
CHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLDLDIQYVKGVGPKRAKLFKKLGIDMVKDLIFYFPRDYEDRSEIVKIEDLIVGEKQTF
CCCCEEHHHCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHEEEHHHHHCCCHHHH
KAYIAGSAREVKTSRVVITKIPVKDGTGAVELVWYNQPYMKNNFKIGEEYIISGKLQFKY
HHHCCCCCHHEECCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECEEEEEE
GQLVVENPVLEKSEEDLNLNTGRIVPVYGLTEGLTQNILRKVIFNALSEYLDEVEEFFEE
CCEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EFLREKGLMNLKEALLNIHFPKDEEKLARAKYRLKYQELFLLQLALFLVKKSVKEKRGIR
HHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
FRKVDIKPFVSNLPFKLTSAQMKVLKEIILDMASDKVMNRLIQGDVGSGKTIVAAFAMYI
EEEEECCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AAKNGYQVAMMAPTEILAKQHYKTLEEIFKGTDIRIGLLSGSLSPSGRKEVLEKIEKGEY
HCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCCE
DVVVGTHALIEEDVSFKNLGLCITDEQHRFGVRQRALLAQKGENPDVLVMTATPIPRTLA
EEEECCHHHHHCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHEE
LILYGDLDISIIDQLPPGRKRVKTYVIPSSMRKKAYEFAIKEVKKGRQVYVVCPLIEESD
EEEECCCCEEEECCCCCCHHHEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCC
KIKAASAEIVYREIYKDAFKEARVGLLHGKMSDSDKERIMEAFVRGEIDILVSTTVIEVG
CCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCEEEEEEEEEEEEE
VNVPNATVMIVENAERFGLAQLHQLRGRVGRSEFQSYCILINYSPSETAKKRLEVLARTS
CCCCCEEEEEEECCCHHHHHHHHHHHHHCCHHHHCCEEEEEEECCCHHHHHHHHHHHCCC
DGFKIAERDLEIRGPGEFLGEKQHGLPEFKIANLFEDIDILKRVQKDVESLLEEDPKLER
CCCEEECCCEEECCCHHHHCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HPKLRQVLISEFYDKVKDIILN
CHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]