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The map label for this gene is AvtA3 [C]

Identifier: 20807815

GI number: 20807815

Start: 1351096

End: 1352283

Strand: Reverse

Name: AvtA3 [C]

Synonym: TTE1368

Alternate gene names: 20807815

Gene position: 1352283-1351096 (Counterclockwise)

Preceding gene: 20807816

Following gene: 20807814

Centisome position: 50.28

GC content: 36.11

Gene sequence:

>1188_bases
TTGAATTTATCTCAAAATGCTTTACAAATTACTCCTTCAATGACTTTAGAGATAACGGCAAAAGCAAAACAGCTGAAAGC
CCAAGGAGTGGATGTCATAGACTTTGGAGTCGGTGAACCGGATTTTGATACTCCTTCCTACATAAAAGAAGCTGCTATTG
ACGCTATAAAGAGAGGATATACTAAATACACTCCTTCATCAGGAATTCCCGAGTTAAAAAAGGCTATATGCGAAAAATTG
CTAAAAGATAACGGACTTAGTTACACTCCCGAACAAATTGTGGTTTCAAACGGCGCAAAACATTCGATATACAATGCTCT
TTCTGCAATTTTAAATCCTGGCGATGAAGTGATAATACCTGTACCTTACTGGCTCAGTTATCCTGAAATGGTAAGATTAG
CCTACGGAAAACCTGTTTTCGTTCATACAAAGGAAGAAAATGATTTTAAAATAACCGCTGAAGAGTTAGAAAATGCCATA
ACTCCAAAGACAAAAGCTATAATTTTAAATAGCCCAAACAATCCTTCAGGAGCTGTCTACACTAAAGAAGAGTTAGAAGA
AATTGCCAGAGTAGTTGAAGAAGCAAATATTTTTGTGATTTCTGATGAAATATACGAAAAACTCATATACGAAGGAGAAC
ACGTTAGCATTGCTTCATTTGGAGAAAAAATCAAAGAACTCACAATTGTAGTTAATGGCATATCAAAGGCCTATGCCATG
ACTGGATGGAGAATAGGCTATACGGCTTCTTCACTAGAAGTTGCAAAAGTCATGTCAAATATTCAAAGTCACACTACATC
AAACCCCAATTCAATTGCCCAGTACGCTAGCGTTGCTGCTTTACAAGGAGGAGAAGAAGAAATAGAAAAAATGAAAGAAG
AATTTAACAGAAGAAGGCTTTATATGGTGGAGAGGGTAAATAAAATAAAAGATTTGAAATGTTCTACTCCAAAAGGAGCC
TTTTATGTGATGGTAAATATAGAAAAATACATTGGTAGGGAGTTAAATGGAAAGACAATAAACGGTTCTTTGGACTTTGC
AAGTGCTTTGATTGACGGAGCAAATGTAGCTGTGGTACCTGCTTTGCCTTTTGGAATGGACAACTATATAAGGATGTCCT
ACGCTACATCTCTTGAAAATATTAAGAAGGGCCTTGACAGAATTGAGGATTTTTTAAGTAAAAGCTAA

Upstream 100 bases:

>100_bases
GAAATTTTAAAAAGTAAAGCTAGAAATTTGGATAGAAATTTGAAAACTTATAAGTTAAAATAATAATTGTGATTCATATG
ACAATTTGGAGGTGTAAAAA

Downstream 100 bases:

>100_bases
ATAAAGCGAATAAAAACGTAAACAAAAGCCCCTGTTTTTACATCTTACAGGGGCTTTAATAAATATTTTAAAAGCAGGAG
GAAGGAAATATGAGAGAGGT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MNLSQNALQITPSMTLEITAKAKQLKAQGVDVIDFGVGEPDFDTPSYIKEAAIDAIKRGYTKYTPSSGIPELKKAICEKL
LKDNGLSYTPEQIVVSNGAKHSIYNALSAILNPGDEVIIPVPYWLSYPEMVRLAYGKPVFVHTKEENDFKITAEELENAI
TPKTKAIILNSPNNPSGAVYTKEELEEIARVVEEANIFVISDEIYEKLIYEGEHVSIASFGEKIKELTIVVNGISKAYAM
TGWRIGYTASSLEVAKVMSNIQSHTTSNPNSIAQYASVAALQGGEEEIEKMKEEFNRRRLYMVERVNKIKDLKCSTPKGA
FYVMVNIEKYIGRELNGKTINGSLDFASALIDGANVAVVPALPFGMDNYIRMSYATSLENIKKGLDRIEDFLSKS

Sequences:

>Translated_395_residues
MNLSQNALQITPSMTLEITAKAKQLKAQGVDVIDFGVGEPDFDTPSYIKEAAIDAIKRGYTKYTPSSGIPELKKAICEKL
LKDNGLSYTPEQIVVSNGAKHSIYNALSAILNPGDEVIIPVPYWLSYPEMVRLAYGKPVFVHTKEENDFKITAEELENAI
TPKTKAIILNSPNNPSGAVYTKEELEEIARVVEEANIFVISDEIYEKLIYEGEHVSIASFGEKIKELTIVVNGISKAYAM
TGWRIGYTASSLEVAKVMSNIQSHTTSNPNSIAQYASVAALQGGEEEIEKMKEEFNRRRLYMVERVNKIKDLKCSTPKGA
FYVMVNIEKYIGRELNGKTINGSLDFASALIDGANVAVVPALPFGMDNYIRMSYATSLENIKKGLDRIEDFLSKS
>Mature_395_residues
MNLSQNALQITPSMTLEITAKAKQLKAQGVDVIDFGVGEPDFDTPSYIKEAAIDAIKRGYTKYTPSSGIPELKKAICEKL
LKDNGLSYTPEQIVVSNGAKHSIYNALSAILNPGDEVIIPVPYWLSYPEMVRLAYGKPVFVHTKEENDFKITAEELENAI
TPKTKAIILNSPNNPSGAVYTKEELEEIARVVEEANIFVISDEIYEKLIYEGEHVSIASFGEKIKELTIVVNGISKAYAM
TGWRIGYTASSLEVAKVMSNIQSHTTSNPNSIAQYASVAALQGGEEEIEKMKEEFNRRRLYMVERVNKIKDLKCSTPKGA
FYVMVNIEKYIGRELNGKTINGSLDFASALIDGANVAVVPALPFGMDNYIRMSYATSLENIKKGLDRIEDFLSKS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=321, Percent_Identity=32.7102803738318, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI56713256, Length=321, Percent_Identity=32.7102803738318, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI95147551, Length=378, Percent_Identity=26.1904761904762, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI169881279, Length=378, Percent_Identity=26.1904761904762, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI169881281, Length=289, Percent_Identity=25.2595155709343, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=22.7748691099476, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI187936925, Length=332, Percent_Identity=26.8072289156627, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI14211921, Length=332, Percent_Identity=26.8072289156627, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI149944424, Length=314, Percent_Identity=26.7515923566879, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI215599424, Length=400, Percent_Identity=21.5, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI19263340, Length=400, Percent_Identity=21.5, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1786816, Length=393, Percent_Identity=25.4452926208651, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1788627, Length=333, Percent_Identity=31.5315315315315, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788722, Length=390, Percent_Identity=28.7179487179487, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787909, Length=368, Percent_Identity=22.8260869565217, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790797, Length=257, Percent_Identity=24.124513618677, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787710, Length=211, Percent_Identity=25.1184834123223, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=380, Percent_Identity=26.5789473684211, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI71994472, Length=285, Percent_Identity=27.719298245614, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71994476, Length=285, Percent_Identity=27.719298245614, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17567369, Length=262, Percent_Identity=28.2442748091603, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71981209, Length=372, Percent_Identity=22.5806451612903, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71981215, Length=203, Percent_Identity=24.6305418719212, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=402, Percent_Identity=29.3532338308458, Blast_Score=145, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6323118, Length=398, Percent_Identity=24.1206030150754, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320317, Length=374, Percent_Identity=22.7272727272727, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28573069, Length=349, Percent_Identity=27.7936962750716, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24646114, Length=349, Percent_Identity=27.7936962750716, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573067, Length=349, Percent_Identity=27.7936962750716, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573065, Length=349, Percent_Identity=27.7936962750716, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI18859735, Length=315, Percent_Identity=22.5396825396825, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24641770, Length=339, Percent_Identity=25.3687315634218, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641760, Length=339, Percent_Identity=25.3687315634218, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641768, Length=339, Percent_Identity=25.3687315634218, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641766, Length=339, Percent_Identity=25.3687315634218, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24641764, Length=339, Percent_Identity=25.3687315634218, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45551451, Length=343, Percent_Identity=24.7813411078717, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43705; Mature: 43705

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00105 AA_TRANSFER_CLASS_1 ; PS01319 RBFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSQNALQITPSMTLEITAKAKQLKAQGVDVIDFGVGEPDFDTPSYIKEAAIDAIKRGY
CCCCCCCEEECCCEEEEEEHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPSSGIPELKKAICEKLLKDNGLSYTPEQIVVSNGAKHSIYNALSAILNPGDEVIIP
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHEECCCCHHHHHHHHHHHHCCCCCEEEE
VPYWLSYPEMVRLAYGKPVFVHTKEENDFKITAEELENAITPKTKAIILNSPNNPSGAVY
CHHHHCCHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHCCCCCCEEEEEECCCCCCCCEE
TKEELEEIARVVEEANIFVISDEIYEKLIYEGEHVSIASFGEKIKELTIVVNGISKAYAM
EHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCEEHHHHHHHHHHHHHEEECHHHHHHH
TGWRIGYTASSLEVAKVMSNIQSHTTSNPNSIAQYASVAALQGGEEEIEKMKEEFNRRRL
CCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YMVERVNKIKDLKCSTPKGAFYVMVNIEKYIGRELNGKTINGSLDFASALIDGANVAVVP
HHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHCCCCCCCEECCCHHHHHHHHCCCCEEEEE
ALPFGMDNYIRMSYATSLENIKKGLDRIEDFLSKS
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLSQNALQITPSMTLEITAKAKQLKAQGVDVIDFGVGEPDFDTPSYIKEAAIDAIKRGY
CCCCCCCEEECCCEEEEEEHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPSSGIPELKKAICEKLLKDNGLSYTPEQIVVSNGAKHSIYNALSAILNPGDEVIIP
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHEECCCCHHHHHHHHHHHHCCCCCEEEE
VPYWLSYPEMVRLAYGKPVFVHTKEENDFKITAEELENAITPKTKAIILNSPNNPSGAVY
CHHHHCCHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHCCCCCCEEEEEECCCCCCCCEE
TKEELEEIARVVEEANIFVISDEIYEKLIYEGEHVSIASFGEKIKELTIVVNGISKAYAM
EHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCEEHHHHHHHHHHHHHEEECHHHHHHH
TGWRIGYTASSLEVAKVMSNIQSHTTSNPNSIAQYASVAALQGGEEEIEKMKEEFNRRRL
CCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YMVERVNKIKDLKCSTPKGAFYVMVNIEKYIGRELNGKTINGSLDFASALIDGANVAVVP
HHHHHHHHHHCCCCCCCCCEEEEEEEEHHHHCCCCCCCEECCCHHHHHHHHCCCCEEEEE
ALPFGMDNYIRMSYATSLENIKKGLDRIEDFLSKS
CCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1990006; 2155199 [H]