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The map label for this gene is GpmB [H]

Identifier: 20807793

GI number: 20807793

Start: 1329516

End: 1330136

Strand: Direct

Name: GpmB [H]

Synonym: TTE1346

Alternate gene names: 20807793

Gene position: 1329516-1330136 (Clockwise)

Preceding gene: 20807792

Following gene: 20807794

Centisome position: 49.43

GC content: 35.75

Gene sequence:

>621_bases
ATGGTTACAAGACTTTATATAGCAAGGCACGGCCAGTCAAAGTGGAATTTAGAGAGCAGAATGCAGGGTATGAAAGATAT
TGAACTGACCCAATTAGGGTTGGAACAGGCTGAATTGCTTGCAAAAAGACTGAAAGGTGAAAACATAGATTGTATATATT
CTAGTGACTTAAAAAGAGCTTATACCACCGCAGAAATAATTTCAAAAGAAATAAATGCCCCCATAGTAAAAATAGAGGAA
TTTAGGGAAATGTCCTTTGGAGTTTGGGAAGGGCTTACTGCGAAGGAGATAGAAGAAAACTATCAAGAACTTTATGACCT
CTGGAAAACAGACCCTAGACATGTCCTTATAGAAAATGCGGAAACATTAAAAGAGGTCCAAAAGAGAATGCTCACAAAGA
CAAAAGAGATTGTAGAAGAGAATTGGGGAAAAAATATTCTAATTGTATCTCATGGCACTTCTATTAAAGCTCTAATTTTA
GGATTGCTGGAAATCGATTTGAGCTTTTACCCTAGCTTTAGAATGGATAATGCTTCTCTTAGCATAATAGATATAAAAGA
AAACAAAAAAGCAGTTCTAGTTTTGTATAACGATACCTGCCATTTAGGAGAGAGGAAGTAG

Upstream 100 bases:

>100_bases
GGTGGGAATAAGTCCTAGAGAATGGAAAGTATCTAAGCTTTCCTATGGAGACCAAATCTTTTATCTTAATTTTGCATAAC
TGGGAGGAAATGAAAAGTAA

Downstream 100 bases:

>100_bases
AAATGAAAAAAGTATTCGTAATAGGCGGCGGAGCTGCTGGAATGATGGCGGCACTGGCAGCAGCAATGACAGGAAAAAAG
GTGAGCCTTTTTGAAAAGAA

Product: phosphoglycerate mutase/fructose-2,6-bisphosphatase

Products: 3-phospho-D-glycerate

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MVTRLYIARHGQSKWNLESRMQGMKDIELTQLGLEQAELLAKRLKGENIDCIYSSDLKRAYTTAEIISKEINAPIVKIEE
FREMSFGVWEGLTAKEIEENYQELYDLWKTDPRHVLIENAETLKEVQKRMLTKTKEIVEENWGKNILIVSHGTSIKALIL
GLLEIDLSFYPSFRMDNASLSIIDIKENKKAVLVLYNDTCHLGERK

Sequences:

>Translated_206_residues
MVTRLYIARHGQSKWNLESRMQGMKDIELTQLGLEQAELLAKRLKGENIDCIYSSDLKRAYTTAEIISKEINAPIVKIEE
FREMSFGVWEGLTAKEIEENYQELYDLWKTDPRHVLIENAETLKEVQKRMLTKTKEIVEENWGKNILIVSHGTSIKALIL
GLLEIDLSFYPSFRMDNASLSIIDIKENKKAVLVLYNDTCHLGERK
>Mature_206_residues
MVTRLYIARHGQSKWNLESRMQGMKDIELTQLGLEQAELLAKRLKGENIDCIYSSDLKRAYTTAEIISKEINAPIVKIEE
FREMSFGVWEGLTAKEIEENYQELYDLWKTDPRHVLIENAETLKEVQKRMLTKTKEIVEENWGKNILIVSHGTSIKALIL
GLLEIDLSFYPSFRMDNASLSIIDIKENKKAVLVLYNDTCHLGERK

Specific function: Phosphatase with broad substrate specificity. Does not have phosphoglycerate mutase activtiy [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=192, Percent_Identity=30.7291666666667, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790856, Length=188, Percent_Identity=32.4468085106383, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1786970, Length=190, Percent_Identity=28.4210526315789, Blast_Score=69, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324857, Length=212, Percent_Identity=31.6037735849057, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 5.4.2.1

Molecular weight: Translated: 23863; Mature: 23863

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTRLYIARHGQSKWNLESRMQGMKDIELTQLGLEQAELLAKRLKGENIDCIYSSDLKRA
CCEEEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHH
YTTAEIISKEINAPIVKIEEFREMSFGVWEGLTAKEIEENYQELYDLWKTDPRHVLIENA
HHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCH
ETLKEVQKRMLTKTKEIVEENWGKNILIVSHGTSIKALILGLLEIDLSFYPSFRMDNASL
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCE
SIIDIKENKKAVLVLYNDTCHLGERK
EEEEECCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MVTRLYIARHGQSKWNLESRMQGMKDIELTQLGLEQAELLAKRLKGENIDCIYSSDLKRA
CCEEEEEEECCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHH
YTTAEIISKEINAPIVKIEEFREMSFGVWEGLTAKEIEENYQELYDLWKTDPRHVLIENA
HHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCH
ETLKEVQKRMLTKTKEIVEENWGKNILIVSHGTSIKALILGLLEIDLSFYPSFRMDNASL
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCEEECCCCE
SIIDIKENKKAVLVLYNDTCHLGERK
EEEEECCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-phospho-D-glycerate

Specific reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]