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The map label for this gene is HflX [H]

Identifier: 20807587

GI number: 20807587

Start: 1131245

End: 1132531

Strand: Direct

Name: HflX [H]

Synonym: TTE1127

Alternate gene names: 20807587

Gene position: 1131245-1132531 (Clockwise)

Preceding gene: 20807586

Following gene: 20807589

Centisome position: 42.06

GC content: 38.38

Gene sequence:

>1287_bases
TTGCAAAAGATAGAATATATTATAATTACAAAACTTTGGGTTGGTGATTGTATGGAAGAACTTGCAAGAGATAAGGAAAG
AGCTATTTTAGTTGCTATTATTTCTTCTCCTGAGGATGAAGAAACGCTTAATGAATTAAAAGAGCTTGCAGTGACTGCCG
GAGCTGAAGTGATTGGAATACTGACCCAAAAAAAGAAGGGGATAAACAAGGCTCATTACATTGGCAAAGGCAAACTGGAA
GAATTGAAGATGTTTGTTGAGAATCAGCAGGCTGACTTGGTGATTGTAAATGACGAACTCACAGGGACACAGATAAAAAA
TCTTGAGGATGCTTTAGGCGTCAAAATCGTAGATAGAACTAACCTCATATTGGATATATTTGCCAAAAGAGCTCGCTCAA
AAGAGGGAATGCTTCAGGTAGAATTGGCTCAGCTAAAATATCGTTTGCCAAGACTTGTAGGCTTGGGAGGGCAGCTTTCC
AGGCTGGGAGGAGGAATAGGGACAAGAGGGCCGGGGGAGACAAAATTAGAAGTTGATAGAAGACATATCAGGAATAGGAT
AAAGGCTATAGAGGAGAAGTTAGAAGAATTAGAGAAACATAGAAATTTGCAGAGGCAAAGAAGAAAGAAAAATCAAATTC
CCGTTGTGGCAATTGTGGGTTACACCAATGCAGGAAAATCGACTTTGTTAAATGCTTTGACAGGTGCTGATGCTTATGTG
GAAGATAAATTATTTGCCACATTAGATCCAACTGCTAGAAAGCTTGTGCTTCCTTCAGGCAGAGAAGTAATTTTGACCGA
TACAGTTGGGTTTATAAGAAAACTTCCGCATGATCTGGTGGAGGCCTTTAAATCTACCTTGGAAGAAGTGAAGTATGCGG
ATTTGCTGCTGCATGTGATTGATGTAACATCTCCTGACATGGATGAAAAGATAAAAGTTGTGGAGAAGGTGCTTTCTGAT
TTGGGAGCAATTGAAACTCCCAGGATAAATGTCTATAACAAGATAGACCTTTTGGAAATTGTACCTTCAGGGAATAACAG
GGATATTTACATATCTGCAAAAAATAAAATAGGGCTTGACAGGCTTTTAGAGGCTATTGAAAGAGAGCTTTTTAAAGAGA
CAGAGGTGGTGAGTTTTTTATTCCCATACGAAAAAACGAGAGAGTATAATTATTTAAAAGAGAGAGGGAAGGTGATTGAG
GAAGATTTTGATGAAAAAGGGATATCAGTAAAAGCTGAGGTTACGTGTGAGATAAAAGAAAGGCTTAGGAATTTTATTAT
CTCTTGA

Upstream 100 bases:

>100_bases
AGCAGGGCAGAAGCTTTTTGCTTCAGAGTATTTTGATATTGTGATTCAAAATTAAGCCAAGGAGCCTCCGAAGAGGAGGC
TTTTTATATAAGTTGCTTTT

Downstream 100 bases:

>100_bases
TGGCGTTGTATTCTGCTTTTTCCTGAGCTTTAACGTTTTTTACTACTTGTACAATTTTTTTGTAAGATTTTTGCGTTCCG
TAAGTTACAAGAGGCCTTCC

Product: GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MQKIEYIIITKLWVGDCMEELARDKERAILVAIISSPEDEETLNELKELAVTAGAEVIGILTQKKKGINKAHYIGKGKLE
ELKMFVENQQADLVIVNDELTGTQIKNLEDALGVKIVDRTNLILDIFAKRARSKEGMLQVELAQLKYRLPRLVGLGGQLS
RLGGGIGTRGPGETKLEVDRRHIRNRIKAIEEKLEELEKHRNLQRQRRKKNQIPVVAIVGYTNAGKSTLLNALTGADAYV
EDKLFATLDPTARKLVLPSGREVILTDTVGFIRKLPHDLVEAFKSTLEEVKYADLLLHVIDVTSPDMDEKIKVVEKVLSD
LGAIETPRINVYNKIDLLEIVPSGNNRDIYISAKNKIGLDRLLEAIERELFKETEVVSFLFPYEKTREYNYLKERGKVIE
EDFDEKGISVKAEVTCEIKERLRNFIIS

Sequences:

>Translated_428_residues
MQKIEYIIITKLWVGDCMEELARDKERAILVAIISSPEDEETLNELKELAVTAGAEVIGILTQKKKGINKAHYIGKGKLE
ELKMFVENQQADLVIVNDELTGTQIKNLEDALGVKIVDRTNLILDIFAKRARSKEGMLQVELAQLKYRLPRLVGLGGQLS
RLGGGIGTRGPGETKLEVDRRHIRNRIKAIEEKLEELEKHRNLQRQRRKKNQIPVVAIVGYTNAGKSTLLNALTGADAYV
EDKLFATLDPTARKLVLPSGREVILTDTVGFIRKLPHDLVEAFKSTLEEVKYADLLLHVIDVTSPDMDEKIKVVEKVLSD
LGAIETPRINVYNKIDLLEIVPSGNNRDIYISAKNKIGLDRLLEAIERELFKETEVVSFLFPYEKTREYNYLKERGKVIE
EDFDEKGISVKAEVTCEIKERLRNFIIS
>Mature_428_residues
MQKIEYIIITKLWVGDCMEELARDKERAILVAIISSPEDEETLNELKELAVTAGAEVIGILTQKKKGINKAHYIGKGKLE
ELKMFVENQQADLVIVNDELTGTQIKNLEDALGVKIVDRTNLILDIFAKRARSKEGMLQVELAQLKYRLPRLVGLGGQLS
RLGGGIGTRGPGETKLEVDRRHIRNRIKAIEEKLEELEKHRNLQRQRRKKNQIPVVAIVGYTNAGKSTLLNALTGADAYV
EDKLFATLDPTARKLVLPSGREVILTDTVGFIRKLPHDLVEAFKSTLEEVKYADLLLHVIDVTSPDMDEKIKVVEKVLSD
LGAIETPRINVYNKIDLLEIVPSGNNRDIYISAKNKIGLDRLLEAIERELFKETEVVSFLFPYEKTREYNYLKERGKVIE
EDFDEKGISVKAEVTCEIKERLRNFIIS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=238, Percent_Identity=37.3949579831933, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI310124269, Length=214, Percent_Identity=38.785046728972, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI310124267, Length=214, Percent_Identity=38.785046728972, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI310124171, Length=214, Percent_Identity=38.785046728972, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI310124169, Length=214, Percent_Identity=38.785046728972, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI310133116, Length=222, Percent_Identity=38.2882882882883, Blast_Score=143, Evalue=3e-34,
Organism=Escherichia coli, GI1790615, Length=401, Percent_Identity=43.142144638404, Blast_Score=301, Evalue=7e-83,
Organism=Caenorhabditis elegans, GI17561038, Length=300, Percent_Identity=32.6666666666667, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24650079, Length=326, Percent_Identity=35.2760736196319, Blast_Score=146, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48468; Mature: 48468

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIEYIIITKLWVGDCMEELARDKERAILVAIISSPEDEETLNELKELAVTAGAEVIGI
CCCEEEEEEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHH
LTQKKKGINKAHYIGKGKLEELKMFVENQQADLVIVNDELTGTQIKNLEDALGVKIVDRT
HHHHHCCCCHHHCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHCEEEECCC
NLILDIFAKRARSKEGMLQVELAQLKYRLPRLVGLGGQLSRLGGGIGTRGPGETKLEVDR
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHH
RHIRNRIKAIEEKLEELEKHRNLQRQRRKKNQIPVVAIVGYTNAGKSTLLNALTGADAYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCHHH
EDKLFATLDPTARKLVLPSGREVILTDTVGFIRKLPHDLVEAFKSTLEEVKYADLLLHVI
HCCEEEEECCCHHEEECCCCCEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
DVTSPDMDEKIKVVEKVLSDLGAIETPRINVYNKIDLLEIVPSGNNRDIYISAKNKIGLD
HCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCEEEEEEECCCCCCEEEEEECCCCCHH
RLLEAIERELFKETEVVSFLFPYEKTREYNYLKERGKVIEEDFDEKGISVKAEVTCEIKE
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHCCCCCCCEEEEEEEHHHHH
RLRNFIIS
HHHHHCCC
>Mature Secondary Structure
MQKIEYIIITKLWVGDCMEELARDKERAILVAIISSPEDEETLNELKELAVTAGAEVIGI
CCCEEEEEEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHH
LTQKKKGINKAHYIGKGKLEELKMFVENQQADLVIVNDELTGTQIKNLEDALGVKIVDRT
HHHHHCCCCHHHCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHCEEEECCC
NLILDIFAKRARSKEGMLQVELAQLKYRLPRLVGLGGQLSRLGGGIGTRGPGETKLEVDR
HHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHH
RHIRNRIKAIEEKLEELEKHRNLQRQRRKKNQIPVVAIVGYTNAGKSTLLNALTGADAYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCHHH
EDKLFATLDPTARKLVLPSGREVILTDTVGFIRKLPHDLVEAFKSTLEEVKYADLLLHVI
HCCEEEEECCCHHEEECCCCCEEEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
DVTSPDMDEKIKVVEKVLSDLGAIETPRINVYNKIDLLEIVPSGNNRDIYISAKNKIGLD
HCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCEEEEEEECCCCCCEEEEEECCCCCHH
RLLEAIERELFKETEVVSFLFPYEKTREYNYLKERGKVIEEDFDEKGISVKAEVTCEIKE
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHCCCCCCCEEEEEEEHHHHH
RLRNFIIS
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]