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The map label for this gene is Rtn [C]

Identifier: 20807551

GI number: 20807551

Start: 1083198

End: 1085579

Strand: Reverse

Name: Rtn [C]

Synonym: TTE1081

Alternate gene names: 20807551

Gene position: 1085579-1083198 (Counterclockwise)

Preceding gene: 20807553

Following gene: 20807539

Centisome position: 40.36

GC content: 37.78

Gene sequence:

>2382_bases
ATGATAGAGAAGATGCCTAGTGAGAGGAAAAATAAGAGTTTTATTGAAGAATCAAAGAAATCAATTGCTTATCTTCAGAA
GAAAGAAGAATTTTTAAGCAGAATTTTTGAAAACGAGCAGATGCTTATAGTAGTCTGGGCATTGGATGGTAGAGTAGTTT
GGTTCAACAGATATACCCAGGCTGTAATTGGTATAGCCGTTGAAGAACAAACAGAGAGGATAGATATAAGTTCAATAATT
CCCAGGGACATGATAAGCCGTATAAAAGAAAATTTGGACGATACTGAAGATAGAGGCATTCATTACAAATGTGAAAATCC
AATGGTTTTGAAGGATGGCAGACAAATTTATATTATGTGGCATAACAGTATTATTTGCGATGATGAAGGAAACAGGTATA
TTGTTTCAACTGGTATAGACATTACAGACCTAAAGAATGCCGAAAGAAGACTTGAAGAAGCAAATAGTAACCTTTTTGCT
TTAAACGAGGAATTGATGGCTCAACAGGAAGAGCTCTCTGCAATGAATGAAAAACTTATGGCCCGAGAAGAGGAGTTGAG
GCAGAACTTAATTGAAATAAAAAGGCAGCAAGATGAATTGAAAAGAAGCGAAGAACGCTACAGACTGGTAGTTGAAGGAG
CAAGCGATGGACTATGGGACTGGGATTTGATAACGGATACGGCTTACATATCCGAGAGGTGGAAGGATATCATTGGTTTA
GATAAAGAAGTAGTAAACAACTATTATGAAACATGGATTAAATTCATTCATCCTAGAGATATTAAAATAGTCATCAATAA
TCTACGTAATCATCTTGAGAAAAAGACACCATTTTATTTATGCGAATACAGAATCAAAACAAAAGACGGTAGATATATTT
GGGTTCTAAGCAGGGGAAAGGCATTGTGGGATGAAGAGGGCAGAGCCATAAGAATAGCAGGGTCGCACACGGATATTACT
GAACGGAAACAGATGGAAAGCAAGTTAAAATACATGGCATTCTATGATCCTTTAACTGGCCTTCCTCGCCGGGAGGTGTT
TATGGATAGGCTCAAAATTGCCATGGCAGATGCAAAAAGGAATGGGAAGAAACTTGCAGTGTTTTTTGTCGACCTTGATA
ATTTCAAAACAATCAACGACTCCCTGGGACATCATATAGGTGACAGGCTATTGAAAAAGGTTGCCAGGAAACTGAAAGCG
TGTCTGCGTGAATCAGATACAGTATCCAGAGTGGGCGGTGATGAGTTTGTTATTTTGCTACCTGACATAATTAATATTGA
CGATACAAATAAGGTTGCAAACAGAATATTGGAACTTTTCAACCAACCGATAAAGTTCAATAATTATGAATTGTATGTGA
CTATTAGCATAGGTATTGCCATATATCCTGACCATGGAAAAAATGAAAGAGCTATAGTCAAAAATGCAGATATAGCGATG
TACAAGGCTAAAAGAGATGGGAAAAATAGTTTTCAATATTTTGACAGTATTACGAAGAAAGAAGTCGAAATTGCCAGCAC
AATAAGAAGAGATTTAAGGTTTGCTTTGGAAAAAGGTCAGTTCTTTTTGCACTATCAGCCTATTGTTGATGCAAGGACTG
GTAAAGTAGTGAGTATGGAGGCACTGTTGAGGTGGCAGCATCCTAAAAAAGGACTGATCAGTCCCATTCATTTTATTCCA
ATTGCTGAAGAAACACGACAAATAATATCTATAGGTGAATGGGTGTTAAGGACAGCCTGCAAGCAAATGAAAGAATGGCG
TAATATGGGGTATTATGGTTTTAGTGTTTCGGTGAATGTTTCAGTGCATCAGCTGCAGCAACCTGATTTTGCAAAGGTTG
TATTTGATATACTAAACGAAATTGAACTTGAACCAAGATTCTTAGAACTGGAGATTACTGAAACCGTCCTTATAGAAGCA
ATGGATACGGTGGTTAGAAACCTTTATCGCTTGAAGGAAATGGGGGTCAAAATAATAATAGATGATTTCGGAACGGAAAA
TAGTTCTTTCAAATACCTCCAAAAATTTACGGTTGATGGTTTGAAAATTGACAGGTCGTTTGTGAGCGAGATAAAGGTAG
AGGTAAATAAGGCTATTGTCGATGCGATTACTTTCTTGGGGCACAGGATGAAACTCGGCGTAACTGCCGAAGGTGTGGAA
ACAAAAGAACAGCTTGATTGTCTTGTAGAGAGCGGGTGCGACAAAGTTCAAGGTTATTATTTCAGCAAACCGTTGCCTCC
AGACGAGGCCATTCGAATGGTTCAGAAAGAATCCAATTATTTCATCTTTTCTCCTTCTACCCAAAAGTGTTGCAAGAAAG
TAGACGGAACAAAAAAACATAGTGGAAAGGATAAGACCTTAGGGAAGTCTGAAAATACTTGA

Upstream 100 bases:

>100_bases
CCTACGATAATTTTACACTATGATATTTGGACAAAGATGAAAAAGTCGTCGAAGACATTGTTTAAAAAATAGTTGTCAAG
AAAGGAGAAATTAATGGCGA

Downstream 100 bases:

>100_bases
AAAAATTTCGCATTCTTATCAAGAGTTGGGATGGGTATTTTCTGAATAGCCGTCCTTAATTGTTGTATTGGAATACAACG
GTATTACTACTAAATACACA

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 793; Mature: 793

Protein sequence:

>793_residues
MIEKMPSERKNKSFIEESKKSIAYLQKKEEFLSRIFENEQMLIVVWALDGRVVWFNRYTQAVIGIAVEEQTERIDISSII
PRDMISRIKENLDDTEDRGIHYKCENPMVLKDGRQIYIMWHNSIICDDEGNRYIVSTGIDITDLKNAERRLEEANSNLFA
LNEELMAQQEELSAMNEKLMAREEELRQNLIEIKRQQDELKRSEERYRLVVEGASDGLWDWDLITDTAYISERWKDIIGL
DKEVVNNYYETWIKFIHPRDIKIVINNLRNHLEKKTPFYLCEYRIKTKDGRYIWVLSRGKALWDEEGRAIRIAGSHTDIT
ERKQMESKLKYMAFYDPLTGLPRREVFMDRLKIAMADAKRNGKKLAVFFVDLDNFKTINDSLGHHIGDRLLKKVARKLKA
CLRESDTVSRVGGDEFVILLPDIINIDDTNKVANRILELFNQPIKFNNYELYVTISIGIAIYPDHGKNERAIVKNADIAM
YKAKRDGKNSFQYFDSITKKEVEIASTIRRDLRFALEKGQFFLHYQPIVDARTGKVVSMEALLRWQHPKKGLISPIHFIP
IAEETRQIISIGEWVLRTACKQMKEWRNMGYYGFSVSVNVSVHQLQQPDFAKVVFDILNEIELEPRFLELEITETVLIEA
MDTVVRNLYRLKEMGVKIIIDDFGTENSSFKYLQKFTVDGLKIDRSFVSEIKVEVNKAIVDAITFLGHRMKLGVTAEGVE
TKEQLDCLVESGCDKVQGYYFSKPLPPDEAIRMVQKESNYFIFSPSTQKCCKKVDGTKKHSGKDKTLGKSENT

Sequences:

>Translated_793_residues
MIEKMPSERKNKSFIEESKKSIAYLQKKEEFLSRIFENEQMLIVVWALDGRVVWFNRYTQAVIGIAVEEQTERIDISSII
PRDMISRIKENLDDTEDRGIHYKCENPMVLKDGRQIYIMWHNSIICDDEGNRYIVSTGIDITDLKNAERRLEEANSNLFA
LNEELMAQQEELSAMNEKLMAREEELRQNLIEIKRQQDELKRSEERYRLVVEGASDGLWDWDLITDTAYISERWKDIIGL
DKEVVNNYYETWIKFIHPRDIKIVINNLRNHLEKKTPFYLCEYRIKTKDGRYIWVLSRGKALWDEEGRAIRIAGSHTDIT
ERKQMESKLKYMAFYDPLTGLPRREVFMDRLKIAMADAKRNGKKLAVFFVDLDNFKTINDSLGHHIGDRLLKKVARKLKA
CLRESDTVSRVGGDEFVILLPDIINIDDTNKVANRILELFNQPIKFNNYELYVTISIGIAIYPDHGKNERAIVKNADIAM
YKAKRDGKNSFQYFDSITKKEVEIASTIRRDLRFALEKGQFFLHYQPIVDARTGKVVSMEALLRWQHPKKGLISPIHFIP
IAEETRQIISIGEWVLRTACKQMKEWRNMGYYGFSVSVNVSVHQLQQPDFAKVVFDILNEIELEPRFLELEITETVLIEA
MDTVVRNLYRLKEMGVKIIIDDFGTENSSFKYLQKFTVDGLKIDRSFVSEIKVEVNKAIVDAITFLGHRMKLGVTAEGVE
TKEQLDCLVESGCDKVQGYYFSKPLPPDEAIRMVQKESNYFIFSPSTQKCCKKVDGTKKHSGKDKTLGKSENT
>Mature_793_residues
MIEKMPSERKNKSFIEESKKSIAYLQKKEEFLSRIFENEQMLIVVWALDGRVVWFNRYTQAVIGIAVEEQTERIDISSII
PRDMISRIKENLDDTEDRGIHYKCENPMVLKDGRQIYIMWHNSIICDDEGNRYIVSTGIDITDLKNAERRLEEANSNLFA
LNEELMAQQEELSAMNEKLMAREEELRQNLIEIKRQQDELKRSEERYRLVVEGASDGLWDWDLITDTAYISERWKDIIGL
DKEVVNNYYETWIKFIHPRDIKIVINNLRNHLEKKTPFYLCEYRIKTKDGRYIWVLSRGKALWDEEGRAIRIAGSHTDIT
ERKQMESKLKYMAFYDPLTGLPRREVFMDRLKIAMADAKRNGKKLAVFFVDLDNFKTINDSLGHHIGDRLLKKVARKLKA
CLRESDTVSRVGGDEFVILLPDIINIDDTNKVANRILELFNQPIKFNNYELYVTISIGIAIYPDHGKNERAIVKNADIAM
YKAKRDGKNSFQYFDSITKKEVEIASTIRRDLRFALEKGQFFLHYQPIVDARTGKVVSMEALLRWQHPKKGLISPIHFIP
IAEETRQIISIGEWVLRTACKQMKEWRNMGYYGFSVSVNVSVHQLQQPDFAKVVFDILNEIELEPRFLELEITETVLIEA
MDTVVRNLYRLKEMGVKIIIDDFGTENSSFKYLQKFTVDGLKIDRSFVSEIKVEVNKAIVDAITFLGHRMKLGVTAEGVE
TKEQLDCLVESGCDKVQGYYFSKPLPPDEAIRMVQKESNYFIFSPSTQKCCKKVDGTKKHSGKDKTLGKSENT

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=470, Percent_Identity=36.1702127659575, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI87081921, Length=432, Percent_Identity=32.6388888888889, Blast_Score=241, Evalue=2e-64,
Organism=Escherichia coli, GI226510982, Length=446, Percent_Identity=27.5784753363229, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI1787055, Length=457, Percent_Identity=29.1028446389497, Blast_Score=162, Evalue=9e-41,
Organism=Escherichia coli, GI1788502, Length=248, Percent_Identity=34.2741935483871, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI87081845, Length=460, Percent_Identity=27.6086956521739, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1786507, Length=266, Percent_Identity=31.9548872180451, Blast_Score=143, Evalue=5e-35,
Organism=Escherichia coli, GI87081980, Length=245, Percent_Identity=35.5102040816327, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI87081743, Length=246, Percent_Identity=32.9268292682927, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI1790496, Length=245, Percent_Identity=32.6530612244898, Blast_Score=132, Evalue=9e-32,
Organism=Escherichia coli, GI1788381, Length=185, Percent_Identity=34.5945945945946, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788849, Length=445, Percent_Identity=27.1910112359551, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788956, Length=162, Percent_Identity=34.5679012345679, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=35.195530726257, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87082096, Length=431, Percent_Identity=24.3619489559165, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI145693134, Length=156, Percent_Identity=39.1025641025641, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=29.7142857142857, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=35.3658536585366, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI87081977, Length=173, Percent_Identity=29.4797687861272, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI87082007, Length=191, Percent_Identity=28.2722513089005, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=32.0987654320988, Blast_Score=83, Evalue=9e-17,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=31.7073170731707, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87081974, Length=103, Percent_Identity=33.9805825242718, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788085, Length=200, Percent_Identity=27, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1787410, Length=223, Percent_Identity=25.5605381165919, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 92309; Mature: 92309

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKMPSERKNKSFIEESKKSIAYLQKKEEFLSRIFENEQMLIVVWALDGRVVWFNRYTQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEEHHHH
AVIGIAVEEQTERIDISSIIPRDMISRIKENLDDTEDRGIHYKCENPMVLKDGRQIYIMW
HHHEEEEECCCCEECHHHCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCEEEEEE
HNSIICDDEGNRYIVSTGIDITDLKNAERRLEEANSNLFALNEELMAQQEELSAMNEKLM
ECEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHH
AREEELRQNLIEIKRQQDELKRSEERYRLVVEGASDGLWDWDLITDTAYISERWKDIIGL
HHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHCC
DKEVVNNYYETWIKFIHPRDIKIVINNLRNHLEKKTPFYLCEYRIKTKDGRYIWVLSRGK
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEEEEECCC
ALWDEEGRAIRIAGSHTDITERKQMESKLKYMAFYDPLTGLPRREVFMDRLKIAMADAKR
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCC
NGKKLAVFFVDLDNFKTINDSLGHHIGDRLLKKVARKLKACLRESDTVSRVGGDEFVILL
CCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEE
PDIINIDDTNKVANRILELFNQPIKFNNYELYVTISIGIAIYPDHGKNERAIVKNADIAM
CCEECCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEECCCCCCCCEEEECCCEEE
YKAKRDGKNSFQYFDSITKKEVEIASTIRRDLRFALEKGQFFLHYQPIVDARTGKVVSME
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEEECCCCCEEEHH
ALLRWQHPKKGLISPIHFIPIAEETRQIISIGEWVLRTACKQMKEWRNMGYYGFSVSVNV
HHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEE
SVHQLQQPDFAKVVFDILNEIELEPRFLELEITETVLIEAMDTVVRNLYRLKEMGVKIII
EHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEE
DDFGTENSSFKYLQKFTVDGLKIDRSFVSEIKVEVNKAIVDAITFLGHRMKLGVTAEGVE
ECCCCCCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEECCCC
TKEQLDCLVESGCDKVQGYYFSKPLPPDEAIRMVQKESNYFIFSPSTQKCCKKVDGTKKH
CHHHHHHHHHCCCCHHCCEEECCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCC
SGKDKTLGKSENT
CCCCCCCCCCCCC
>Mature Secondary Structure
MIEKMPSERKNKSFIEESKKSIAYLQKKEEFLSRIFENEQMLIVVWALDGRVVWFNRYTQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEEHHHH
AVIGIAVEEQTERIDISSIIPRDMISRIKENLDDTEDRGIHYKCENPMVLKDGRQIYIMW
HHHEEEEECCCCEECHHHCCCHHHHHHHHHCCCCCCCCCEEEECCCCEEEECCCEEEEEE
HNSIICDDEGNRYIVSTGIDITDLKNAERRLEEANSNLFALNEELMAQQEELSAMNEKLM
ECEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHH
AREEELRQNLIEIKRQQDELKRSEERYRLVVEGASDGLWDWDLITDTAYISERWKDIIGL
HHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHCC
DKEVVNNYYETWIKFIHPRDIKIVINNLRNHLEKKTPFYLCEYRIKTKDGRYIWVLSRGK
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCEEEEEECCC
ALWDEEGRAIRIAGSHTDITERKQMESKLKYMAFYDPLTGLPRREVFMDRLKIAMADAKR
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCC
NGKKLAVFFVDLDNFKTINDSLGHHIGDRLLKKVARKLKACLRESDTVSRVGGDEFVILL
CCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEE
PDIINIDDTNKVANRILELFNQPIKFNNYELYVTISIGIAIYPDHGKNERAIVKNADIAM
CCEECCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEEEECCCCCCCCEEEECCCEEE
YKAKRDGKNSFQYFDSITKKEVEIASTIRRDLRFALEKGQFFLHYQPIVDARTGKVVSME
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECEEECCCCCEEEHH
ALLRWQHPKKGLISPIHFIPIAEETRQIISIGEWVLRTACKQMKEWRNMGYYGFSVSVNV
HHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEE
SVHQLQQPDFAKVVFDILNEIELEPRFLELEITETVLIEAMDTVVRNLYRLKEMGVKIII
EHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEEE
DDFGTENSSFKYLQKFTVDGLKIDRSFVSEIKVEVNKAIVDAITFLGHRMKLGVTAEGVE
ECCCCCCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCEEECEEECCCC
TKEQLDCLVESGCDKVQGYYFSKPLPPDEAIRMVQKESNYFIFSPSTQKCCKKVDGTKKH
CHHHHHHHHHCCCCHHCCEEECCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCC
SGKDKTLGKSENT
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]