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The map label for this gene is rsbS [H]

Identifier: 20807523

GI number: 20807523

Start: 1052845

End: 1053228

Strand: Direct

Name: rsbS [H]

Synonym: TTE1048

Alternate gene names: 20807523

Gene position: 1052845-1053228 (Clockwise)

Preceding gene: 20807522

Following gene: 20807524

Centisome position: 39.15

GC content: 39.32

Gene sequence:

>384_bases
ATGGACAAAAAAGAGGGAGCGACTATGAAGAATAAAGTAGTGCCAACCATTAAGCTTTATGATTATCTACTTGTTCCAAT
ACAAATTGAACTTGATGACAATACAGTTGAGAGACTGCAGATGCAGATACTCCATGAGATACATGAGAAGGAAGTTCGGG
GAATAATAATCGATGTTAGTATGGTCGATGTAATCGATAGCTATATATCTTTTGTTCTTTCGGAAACGGCTGGCATGGCT
AAGGCTATGGGATGCTATGTCGTTATATGCGGAATTCAACCTCAGGTAGCGCTTACGCTATCCCAGATGGGCATCAAACT
GAAAGACATAATCACTGCCCAGAGCCTTGAGGATGCTATAAATATTCTTGATAAATTGGAATAA

Upstream 100 bases:

>100_bases
AAGCTGGGTGTCGATTTCAATATGGTAATTATAAAAAGAGACTTGGAAAGCGCTCTTAAACATGCAATTGAGATAACATC
TGATAACAGAGGAGGAAGAT

Downstream 100 bases:

>100_bases
GAGATACTTTTTTGATGCTTTTTTGCTTTTAAAGGGGTGATACTAGGTGATAGAAGTGAATCCCCAGGATTACGATATAG
TATTGAAGATAAAAGATGAA

Product: STAS domain-containing protein

Products: NA

Alternate protein names: Stressosome protein rsbS [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MDKKEGATMKNKVVPTIKLYDYLLVPIQIELDDNTVERLQMQILHEIHEKEVRGIIIDVSMVDVIDSYISFVLSETAGMA
KAMGCYVVICGIQPQVALTLSQMGIKLKDIITAQSLEDAINILDKLE

Sequences:

>Translated_127_residues
MDKKEGATMKNKVVPTIKLYDYLLVPIQIELDDNTVERLQMQILHEIHEKEVRGIIIDVSMVDVIDSYISFVLSETAGMA
KAMGCYVVICGIQPQVALTLSQMGIKLKDIITAQSLEDAINILDKLE
>Mature_127_residues
MDKKEGATMKNKVVPTIKLYDYLLVPIQIELDDNTVERLQMQILHEIHEKEVRGIIIDVSMVDVIDSYISFVLSETAGMA
KAMGCYVVICGIQPQVALTLSQMGIKLKDIITAQSLEDAINILDKLE

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 14208; Mature: 14208

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKEGATMKNKVVPTIKLYDYLLVPIQIELDDNTVERLQMQILHEIHEKEVRGIIIDVS
CCCCCCCCCHHCCCCCEEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCEEEEEHH
MVDVIDSYISFVLSETAGMAKAMGCYVVICGIQPQVALTLSQMGIKLKDIITAQSLEDAI
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
NILDKLE
HHHHHCC
>Mature Secondary Structure
MDKKEGATMKNKVVPTIKLYDYLLVPIQIELDDNTVERLQMQILHEIHEKEVRGIIIDVS
CCCCCCCCCHHCCCCCEEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHCEEEEEHH
MVDVIDSYISFVLSETAGMAKAMGCYVVICGIQPQVALTLSQMGIKLKDIITAQSLEDAI
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
NILDKLE
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 8824586; 8682789 [H]