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The map label for this gene is rsbRA [H]

Identifier: 20807522

GI number: 20807522

Start: 1052145

End: 1052879

Strand: Direct

Name: rsbRA [H]

Synonym: TTE1047

Alternate gene names: 20807522

Gene position: 1052145-1052879 (Clockwise)

Preceding gene: 20807521

Following gene: 20807523

Centisome position: 39.12

GC content: 39.32

Gene sequence:

>735_bases
GTGAAAGAGACTATTATTTATAATTTAAAAACGCTTGTAGAAGAAATAGCAGAATCAGATAATACTAAAAAAGAATGGGA
GGATTTTTTGATTAGTCTCGCAGATGCCTTTGGCAGTGAGGATATGAAAGGAAGGATAAAAGAACCTCTCAAAAATTTGC
TGAATTTTATTGATGTAAGTGCTCTGGTAAGAGGGATGGAGCTTTTGAATGCCAGAATTGAAGGGTTCCCCCTTCCAGAA
ATGTTAAAGGTCGTAATCGAAGTATTGGACGAGATAAAAAATGATAAGGAGATGCGCATAAGAGAGCTGGGACACGTACT
TGCCGAACTCGCAACCCCTATAATAAGGATATGGCGTGATGTACTCCTGGTACCTCTTATTGGTACACTTGATAGCCACC
GAGCACAGAGCATGGCTGAAAAACTTCTTGAAAGAACAGCAAGTACTAGGGCAAAGGTGGTTATTGTGGATGTGACAGGA
GTGCCAATGATCGATACGATTGTCGGGGGATTTTTAATAGAAATGTTTAACGCAGTAAAATTGCTTGGCAGTGACGTAAT
TCTGACAGGTATAAAGCCGGAGATAGCTCATACTCTTGTAAAGCTGGGTGTCGATTTCAATATGGTAATTATAAAAAGAG
ACTTGGAAAGCGCTCTTAAACATGCAATTGAGATAACATCTGATAACAGAGGAGGAAGATATGGACAAAAAAGAGGGAGC
GACTATGAAGAATAA

Upstream 100 bases:

>100_bases
TTATTTGAAAAAGGTAAAAAGAGCTCAAATTTAGTGAAAAAATGAGATTTTTCAAGCTTGATTGAGCTAATTACAAAATA
TTGAGATAGGAGTGGGTACG

Downstream 100 bases:

>100_bases
AGTAGTGCCAACCATTAAGCTTTATGATTATCTACTTGTTCCAATACAAATTGAACTTGATGACAATACAGTTGAGAGAC
TGCAGATGCAGATACTCCAT

Product: STAS domain-containing protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MKETIIYNLKTLVEEIAESDNTKKEWEDFLISLADAFGSEDMKGRIKEPLKNLLNFIDVSALVRGMELLNARIEGFPLPE
MLKVVIEVLDEIKNDKEMRIRELGHVLAELATPIIRIWRDVLLVPLIGTLDSHRAQSMAEKLLERTASTRAKVVIVDVTG
VPMIDTIVGGFLIEMFNAVKLLGSDVILTGIKPEIAHTLVKLGVDFNMVIIKRDLESALKHAIEITSDNRGGRYGQKRGS
DYEE

Sequences:

>Translated_244_residues
MKETIIYNLKTLVEEIAESDNTKKEWEDFLISLADAFGSEDMKGRIKEPLKNLLNFIDVSALVRGMELLNARIEGFPLPE
MLKVVIEVLDEIKNDKEMRIRELGHVLAELATPIIRIWRDVLLVPLIGTLDSHRAQSMAEKLLERTASTRAKVVIVDVTG
VPMIDTIVGGFLIEMFNAVKLLGSDVILTGIKPEIAHTLVKLGVDFNMVIIKRDLESALKHAIEITSDNRGGRYGQKRGS
DYEE
>Mature_244_residues
MKETIIYNLKTLVEEIAESDNTKKEWEDFLISLADAFGSEDMKGRIKEPLKNLLNFIDVSALVRGMELLNARIEGFPLPE
MLKVVIEVLDEIKNDKEMRIRELGHVLAELATPIIRIWRDVLLVPLIGTLDSHRAQSMAEKLLERTASTRAKVVIVDVTG
VPMIDTIVGGFLIEMFNAVKLLGSDVILTGIKPEIAHTLVKLGVDFNMVIIKRDLESALKHAIEITSDNRGGRYGQKRGS
DYEE

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 27393; Mature: 27393

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETIIYNLKTLVEEIAESDNTKKEWEDFLISLADAFGSEDMKGRIKEPLKNLLNFIDVS
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALVRGMELLNARIEGFPLPEMLKVVIEVLDEIKNDKEMRIRELGHVLAELATPIIRIWRD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLLVPLIGTLDSHRAQSMAEKLLERTASTRAKVVIVDVTGVPMIDTIVGGFLIEMFNAVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
LLGSDVILTGIKPEIAHTLVKLGVDFNMVIIKRDLESALKHAIEITSDNRGGRYGQKRGS
HHCCCCEEECCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DYEE
CCCC
>Mature Secondary Structure
MKETIIYNLKTLVEEIAESDNTKKEWEDFLISLADAFGSEDMKGRIKEPLKNLLNFIDVS
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
ALVRGMELLNARIEGFPLPEMLKVVIEVLDEIKNDKEMRIRELGHVLAELATPIIRIWRD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VLLVPLIGTLDSHRAQSMAEKLLERTASTRAKVVIVDVTGVPMIDTIVGGFLIEMFNAVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
LLGSDVILTGIKPEIAHTLVKLGVDFNMVIIKRDLESALKHAIEITSDNRGGRYGQKRGS
HHCCCCEEECCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DYEE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]