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The map label for this gene is LdcC2 [H]

Identifier: 20807506

GI number: 20807506

Start: 1028868

End: 1030355

Strand: Reverse

Name: LdcC2 [H]

Synonym: TTE1027

Alternate gene names: 20807506

Gene position: 1030355-1028868 (Counterclockwise)

Preceding gene: 20807509

Following gene: 20807499

Centisome position: 38.31

GC content: 39.99

Gene sequence:

>1488_bases
TTGAAAAAGCTAGATCAAACTCAAACCCCTTTATTTGACGCTCTAATGGAATATGTGAATAATAATACAATTCCCTTCCA
CGTACCGGGACACAAAAAAGGGGAGGGAATGGCCAAAAAATTTCTAGACTTTGTTGGAAAAAATGTGCTCTCAATGGATG
TAACTGTGTTTCAGCAAGTAGACAGCTTGCACAAACCAACAGGTCCTATCAAATACGCTCAAGAGTTGGCAGCAGAAGCT
TTTGGAGCAGACGCAACATTTTTCTCAATACACGGAACCTCTGGAGCCATCCAAGCTATGATTTTAAGCGTAATGGGAGA
AGATGAAAAAATCATTGTACCAAGAAACATTCACAAGTCTGTGACCTCCGGAATCATATTAAGTGGCGCTATACCAATTT
ACATGCAGCCAGAAATTGACAAAAATATCGGGGTTGCCTTGAACGTCACCCCTGAGACGGTCGAAAAAACTTTAAGACAG
CATCCTGATGCAAAAGCGGTTTTAATCATCAACCCAACTTATTACGGAGTTTCTACAGACATAGTAAAAATTGCTGAAAT
TGTCCACGATTATGGAGCAATTTTAATGGTAGATGAAGCTCATGGCCCTCACCTTAAATTTAACGAAAAATTGCCCATTT
CGGCTATGGAAGCAGGAGCCGATATATGCGCTCAAAGCACTCATAAAATTATTGGTTCTATGACACAAAGTTCAATGCTT
CATGTAAAAGGAGACAGGATAGATATAAACAGGGTAAAGCAGGTGATGAGCTTATTACAGACCACAAGCCCTTCATATAT
ACTCCTGGCGTCACTGGACGTAGCAAGAATGCAAATGGCTACAGAAGGAAAGGAACTTCTGGACAGGACTATCGAATTAG
CTGAATACGCCAGAAGAGAGATAAATAAAATTAAAGGGCTTTACTGCTTTGGCGAAGAAATAGTAGGTCGCGATGGCGCT
TATGATTTTGACCCTACAAAAGTGACCATAACTGCCAAAGGATTAGGTATAACTGGGCATCAACTGGAAAGAATCTTAGC
AGAAAAATACTACATTCAAGTAGAGCTTTCGGACATGTACAATGTCCTCTGCGTATTCTCAATTGGAGACACAAAAGAAA
AAGTAGATTACTTGCTTCGCGCTTTAAGAGAGATAAGCGACGAATTGTACGACGAAAACATAGAAGTAGCAAAGCCAATA
GATATTCCAGAAATTCCCGAATTAGTAGTTTCACCTAGATATGCCTTTAACGCTCCTACAGTGGCTCTTCCTCTGAGAGA
AAGTGTAGGGCAGATAAGCGCAGAATTTTTAATGGCATATCCACCTGGAATACCAGTGCTCTGCCCTGGCGAAAGAATAA
CAATGGAAATTATAGAATACGTCGAAAAAATGAAAGAGGCAAATTTAAGCATTCAAGGCACAGAAGACCCAGAGGCAAAT
TATATAAAGGTGGTAAATTACAGACAGGCTCTAAATGTAATCGCATAA

Upstream 100 bases:

>100_bases
AAATTTGAATGGATATGTCTTATAATGAATTGAAGTTATTAATAAGTTTCAATCCGGAGGTTTTTTAAAGATTAAAAACT
ATGAAAGAGGTGTAAAAGGG

Downstream 100 bases:

>100_bases
AAAAGAGTATCTCCCCACGAGAGATACTCTTTTTTATTCTGAAAGCGCTTTGTAGTACTCCTCTATTTCATCGTAGGTCA
TAGCCCCGTTGCTGATGGCC

Product: arginine/lysine/ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MKKLDQTQTPLFDALMEYVNNNTIPFHVPGHKKGEGMAKKFLDFVGKNVLSMDVTVFQQVDSLHKPTGPIKYAQELAAEA
FGADATFFSIHGTSGAIQAMILSVMGEDEKIIVPRNIHKSVTSGIILSGAIPIYMQPEIDKNIGVALNVTPETVEKTLRQ
HPDAKAVLIINPTYYGVSTDIVKIAEIVHDYGAILMVDEAHGPHLKFNEKLPISAMEAGADICAQSTHKIIGSMTQSSML
HVKGDRIDINRVKQVMSLLQTTSPSYILLASLDVARMQMATEGKELLDRTIELAEYARREINKIKGLYCFGEEIVGRDGA
YDFDPTKVTITAKGLGITGHQLERILAEKYYIQVELSDMYNVLCVFSIGDTKEKVDYLLRALREISDELYDENIEVAKPI
DIPEIPELVVSPRYAFNAPTVALPLRESVGQISAEFLMAYPPGIPVLCPGERITMEIIEYVEKMKEANLSIQGTEDPEAN
YIKVVNYRQALNVIA

Sequences:

>Translated_495_residues
MKKLDQTQTPLFDALMEYVNNNTIPFHVPGHKKGEGMAKKFLDFVGKNVLSMDVTVFQQVDSLHKPTGPIKYAQELAAEA
FGADATFFSIHGTSGAIQAMILSVMGEDEKIIVPRNIHKSVTSGIILSGAIPIYMQPEIDKNIGVALNVTPETVEKTLRQ
HPDAKAVLIINPTYYGVSTDIVKIAEIVHDYGAILMVDEAHGPHLKFNEKLPISAMEAGADICAQSTHKIIGSMTQSSML
HVKGDRIDINRVKQVMSLLQTTSPSYILLASLDVARMQMATEGKELLDRTIELAEYARREINKIKGLYCFGEEIVGRDGA
YDFDPTKVTITAKGLGITGHQLERILAEKYYIQVELSDMYNVLCVFSIGDTKEKVDYLLRALREISDELYDENIEVAKPI
DIPEIPELVVSPRYAFNAPTVALPLRESVGQISAEFLMAYPPGIPVLCPGERITMEIIEYVEKMKEANLSIQGTEDPEAN
YIKVVNYRQALNVIA
>Mature_495_residues
MKKLDQTQTPLFDALMEYVNNNTIPFHVPGHKKGEGMAKKFLDFVGKNVLSMDVTVFQQVDSLHKPTGPIKYAQELAAEA
FGADATFFSIHGTSGAIQAMILSVMGEDEKIIVPRNIHKSVTSGIILSGAIPIYMQPEIDKNIGVALNVTPETVEKTLRQ
HPDAKAVLIINPTYYGVSTDIVKIAEIVHDYGAILMVDEAHGPHLKFNEKLPISAMEAGADICAQSTHKIIGSMTQSSML
HVKGDRIDINRVKQVMSLLQTTSPSYILLASLDVARMQMATEGKELLDRTIELAEYARREINKIKGLYCFGEEIVGRDGA
YDFDPTKVTITAKGLGITGHQLERILAEKYYIQVELSDMYNVLCVFSIGDTKEKVDYLLRALREISDELYDENIEVAKPI
DIPEIPELVVSPRYAFNAPTVALPLRESVGQISAEFLMAYPPGIPVLCPGERITMEIIEYVEKMKEANLSIQGTEDPEAN
YIKVVNYRQALNVIA

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1790573, Length=569, Percent_Identity=28.2952548330404, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1786384, Length=552, Percent_Identity=26.8115942028986, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI221142684, Length=583, Percent_Identity=26.5866209262436, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87082193, Length=584, Percent_Identity=23.458904109589, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786909, Length=392, Percent_Identity=22.4489795918367, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 54861; Mature: 54861

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLDQTQTPLFDALMEYVNNNTIPFHVPGHKKGEGMAKKFLDFVGKNVLSMDVTVFQQV
CCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
DSLHKPTGPIKYAQELAAEAFGADATFFSIHGTSGAIQAMILSVMGEDEKIIVPRNIHKS
HHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHH
VTSGIILSGAIPIYMQPEIDKNIGVALNVTPETVEKTLRQHPDAKAVLIINPTYYGVSTD
HHCCEEEECCCCEEECCCCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCCCCHH
IVKIAEIVHDYGAILMVDEAHGPHLKFNEKLPISAMEAGADICAQSTHKIIGSMTQSSML
HHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCEE
HVKGDRIDINRVKQVMSLLQTTSPSYILLASLDVARMQMATEGKELLDRTIELAEYARRE
EEECCEECHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCHHHHHHHHHHHHHHHHHH
INKIKGLYCFGEEIVGRDGAYDFDPTKVTITAKGLGITGHQLERILAEKYYIQVELSDMY
HHHHCCEEEECHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHEEEEEEECCCC
NVLCVFSIGDTKEKVDYLLRALREISDELYDENIEVAKPIDIPEIPELVVSPRYAFNAPT
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHCCCCCCCCCCE
VALPLRESVGQISAEFLMAYPPGIPVLCPGERITMEIIEYVEKMKEANLSIQGTEDPEAN
EEEEHHHHHHHHHHHHHEECCCCCCEEECCCHHHHHHHHHHHHHHHCCCEEECCCCCCCC
YIKVVNYRQALNVIA
EEEEEEHHHHHHHCC
>Mature Secondary Structure
MKKLDQTQTPLFDALMEYVNNNTIPFHVPGHKKGEGMAKKFLDFVGKNVLSMDVTVFQQV
CCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
DSLHKPTGPIKYAQELAAEAFGADATFFSIHGTSGAIQAMILSVMGEDEKIIVPRNIHKS
HHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEECCHHHHH
VTSGIILSGAIPIYMQPEIDKNIGVALNVTPETVEKTLRQHPDAKAVLIINPTYYGVSTD
HHCCEEEECCCCEEECCCCCCCCCEEEECCHHHHHHHHHHCCCCCEEEEECCCCCCCCHH
IVKIAEIVHDYGAILMVDEAHGPHLKFNEKLPISAMEAGADICAQSTHKIIGSMTQSSML
HHHHHHHHHCCCCEEEEECCCCCCEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCEE
HVKGDRIDINRVKQVMSLLQTTSPSYILLASLDVARMQMATEGKELLDRTIELAEYARRE
EEECCEECHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHCHHHHHHHHHHHHHHHHHH
INKIKGLYCFGEEIVGRDGAYDFDPTKVTITAKGLGITGHQLERILAEKYYIQVELSDMY
HHHHCCEEEECHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHEEEEEEECCCC
NVLCVFSIGDTKEKVDYLLRALREISDELYDENIEVAKPIDIPEIPELVVSPRYAFNAPT
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHCCCCCCCCCCE
VALPLRESVGQISAEFLMAYPPGIPVLCPGERITMEIIEYVEKMKEANLSIQGTEDPEAN
EEEEHHHHHHHHHHHHHEECCCCCCEEECCCHHHHHHHHHHHHHHHCCCEEECCCCCCCC
YIKVVNYRQALNVIA
EEEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]