Click here to switch to the map view.

The map label for this gene is NuoE [H]

Identifier: 20807371

GI number: 20807371

Start: 900174

End: 900683

Strand: Direct

Name: NuoE [H]

Synonym: TTE0890

Alternate gene names: 20807371

Gene position: 900174-900683 (Clockwise)

Preceding gene: 20807370

Following gene: 20807372

Centisome position: 33.47

GC content: 39.8

Gene sequence:

>510_bases
ATGCAGGGCATGAAAGAAGCAAGTTTGGAAGAAAAGCTTGTAGAGAAGTTTGGCAAAGATAAGGTTGAGAAGTTCAAAAA
GTCAATAGAAAATTACAGAGAAATCCCCGGTTCACTAATTGCTGTCATGAATGACGCTCAAGAGATTTTTGGATATCTTC
CCATAGAAGTTCAGCTTTTCATCTCACAGGAGATGAAGGTTCCTTTGACGGAGATATTCGGGATTTCGACCTTTTATTCA
AGATTTACTCTGAAGCCTTCTGGAAAGTACAAAATAAACCTTTGCATGGGAACTGCTTGTTATGTTAGAGGAGCTGCTAT
GTTGCTGGAAAAAATTAAGGAAAAGTTGGGCATAGAGGTAGGGGAGACAACAGAAGACGGTAAATTTTCTCTGGAGCCAA
CAAGATGCCTTGGAGCATGTGCACTTGCACCCGTTATGATGATAAACGGCGAAGTTTTTGGAAGGCTTACTCCTAATGAC
GTGGATGAAATACTGAAAAAATTTGAATAG

Upstream 100 bases:

>100_bases
TAAAAAATTAATGAAATTATGATATAATATTAACGAATGATGAATTAAAAGTGCTATGATGAAAATTTTGTGAAATTTCT
CATTCAAGGAGGGAAAGGCA

Downstream 100 bases:

>100_bases
GGATTTATAAATCATGAAAGAGTTGGCTCTCTATATACTAGATTTGGCTCAAAATAGCGTAAGAGCTGGAGCGAAAAATG
TTGAAATTGAAATAGAAGAA

Product: NADH:ubiquinone oxidoreductase 24 kD subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MQGMKEASLEEKLVEKFGKDKVEKFKKSIENYREIPGSLIAVMNDAQEIFGYLPIEVQLFISQEMKVPLTEIFGISTFYS
RFTLKPSGKYKINLCMGTACYVRGAAMLLEKIKEKLGIEVGETTEDGKFSLEPTRCLGACALAPVMMINGEVFGRLTPND
VDEILKKFE

Sequences:

>Translated_169_residues
MQGMKEASLEEKLVEKFGKDKVEKFKKSIENYREIPGSLIAVMNDAQEIFGYLPIEVQLFISQEMKVPLTEIFGISTFYS
RFTLKPSGKYKINLCMGTACYVRGAAMLLEKIKEKLGIEVGETTEDGKFSLEPTRCLGACALAPVMMINGEVFGRLTPND
VDEILKKFE
>Mature_169_residues
MQGMKEASLEEKLVEKFGKDKVEKFKKSIENYREIPGSLIAVMNDAQEIFGYLPIEVQLFISQEMKVPLTEIFGISTFYS
RFTLKPSGKYKINLCMGTACYVRGAAMLLEKIKEKLGIEVGETTEDGKFSLEPTRCLGACALAPVMMINGEVFGRLTPND
VDEILKKFE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=155, Percent_Identity=35.4838709677419, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI1788621, Length=146, Percent_Identity=30.1369863013699, Blast_Score=97, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17561328, Length=167, Percent_Identity=40.1197604790419, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI18859877, Length=133, Percent_Identity=38.3458646616541, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355353, Length=151, Percent_Identity=33.112582781457, Blast_Score=97, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18994; Mature: 18994

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGMKEASLEEKLVEKFGKDKVEKFKKSIENYREIPGSLIAVMNDAQEIFGYLPIEVQLF
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEE
ISQEMKVPLTEIFGISTFYSRFTLKPSGKYKINLCMGTACYVRGAAMLLEKIKEKLGIEV
ECCCCCCCHHHHHHHHHHHHHEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCC
GETTEDGKFSLEPTRCLGACALAPVMMINGEVFGRLTPNDVDEILKKFE
CCCCCCCCEECCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MQGMKEASLEEKLVEKFGKDKVEKFKKSIENYREIPGSLIAVMNDAQEIFGYLPIEVQLF
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEE
ISQEMKVPLTEIFGISTFYSRFTLKPSGKYKINLCMGTACYVRGAAMLLEKIKEKLGIEV
ECCCCCCCHHHHHHHHHHHHHEEECCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCC
GETTEDGKFSLEPTRCLGACALAPVMMINGEVFGRLTPNDVDEILKKFE
CCCCCCCCEECCHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA