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The map label for this gene is Asd [H]

Identifier: 20807315

GI number: 20807315

Start: 839578

End: 840567

Strand: Reverse

Name: Asd [H]

Synonym: TTE0833

Alternate gene names: 20807315

Gene position: 840567-839578 (Counterclockwise)

Preceding gene: 20807316

Following gene: 20807314

Centisome position: 31.25

GC content: 42.12

Gene sequence:

>990_bases
ATGGGAGTTAATGTGGCAATTGTCGGAGCTACCGGCATGGTAGGAAGAACTTTTCTAAAAGTAATGGAAGAAAGAAATTT
TCCTGTCAATAAGCTGTACTTATTCGCATCATCCAAATCTGCCGGTGAAAAACTTTATTTTAAAAACAAAGAGTACATCG
TAGAAGAACTTACAGAGGAAAGCTTCAACAGGGACATACAAATAGCTTTATTCTCAGCAGGAGCTACTGTGAGCAAACAA
TTTGCCCCAATAGCCGCATCCCGTGGAATAGTAGTAATAGATAATTCCAGCGCATGGCGCATGGATGAAAACGTACCTTT
AGTGGTTCCAGAAGTAAACCCAGAAGACATATCATGGCATAAAGGAATAATAGCAAACCCCAATTGTTCCACCATACAGA
TGGTAGTCCCTTTAAAGCCCCTTCATGACAAGTACAGGATAAAGCGCATTGTCGTATCTACTTATCAGGCAGTGTCAGGG
GCAGGCAAAAAAGGCATAGATGACCTCGAAAGAACGCAGAAAGGAGAACCACCCCAGGTATTCCCTCATCCAATAGCGAA
TAACTGCATTCCCCACATTGACTCCTTCACCCCGAGCGGATATACAAAAGAGGAACTCAAAATGATAAACGAGACGAAGA
AAATAATGAAAGATGACTCTATAAAAGTCTCTCCAACCACAGTAAGAGTTCCTGTAGTAAATTCTCACAGCGAATCTGTA
AATGTAGAATTTGCTCGGCCCTATGAGATGAAAGAGTTAATAGAAATTCTAAAAAATGCCCCCGGAGTTGTAGTGATGGA
CGACCCTGAACATAACCTATACCCTCTTGCCACCTTTGCTACAGGGAAAGACGAGGTATTTGTGGGGAGAATAAGAAGGG
ATGAGACAGTCTACAGCGGTGTGAACATGTGGATTGTGGCGGATAACATAAGAAAAGGTGCGGCGACAAATGCCGTGCAG
ATTGCTGAACTTGTAATCAAAAATATGTGA

Upstream 100 bases:

>100_bases
TTATTGACTTCATATAATAGTAATGATATATTTTAAATAAGCAAATCACTTTAATACAGCATAAAATTAAAAAAGCCCGA
ATTAGAGGAGGATTAGAATA

Downstream 100 bases:

>100_bases
AAGGAGAATGGAGCATGCCTGTATTTAAAGGTTCATGTGTGGCCATAGTGACCCCTTTTACTGAAAATGGAGTGAATTTT
GACAAACTTGGCGAATTGAT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MGVNVAIVGATGMVGRTFLKVMEERNFPVNKLYLFASSKSAGEKLYFKNKEYIVEELTEESFNRDIQIALFSAGATVSKQ
FAPIAASRGIVVIDNSSAWRMDENVPLVVPEVNPEDISWHKGIIANPNCSTIQMVVPLKPLHDKYRIKRIVVSTYQAVSG
AGKKGIDDLERTQKGEPPQVFPHPIANNCIPHIDSFTPSGYTKEELKMINETKKIMKDDSIKVSPTTVRVPVVNSHSESV
NVEFARPYEMKELIEILKNAPGVVVMDDPEHNLYPLATFATGKDEVFVGRIRRDETVYSGVNMWIVADNIRKGAATNAVQ
IAELVIKNM

Sequences:

>Translated_329_residues
MGVNVAIVGATGMVGRTFLKVMEERNFPVNKLYLFASSKSAGEKLYFKNKEYIVEELTEESFNRDIQIALFSAGATVSKQ
FAPIAASRGIVVIDNSSAWRMDENVPLVVPEVNPEDISWHKGIIANPNCSTIQMVVPLKPLHDKYRIKRIVVSTYQAVSG
AGKKGIDDLERTQKGEPPQVFPHPIANNCIPHIDSFTPSGYTKEELKMINETKKIMKDDSIKVSPTTVRVPVVNSHSESV
NVEFARPYEMKELIEILKNAPGVVVMDDPEHNLYPLATFATGKDEVFVGRIRRDETVYSGVNMWIVADNIRKGAATNAVQ
IAELVIKNM
>Mature_328_residues
GVNVAIVGATGMVGRTFLKVMEERNFPVNKLYLFASSKSAGEKLYFKNKEYIVEELTEESFNRDIQIALFSAGATVSKQF
APIAASRGIVVIDNSSAWRMDENVPLVVPEVNPEDISWHKGIIANPNCSTIQMVVPLKPLHDKYRIKRIVVSTYQAVSGA
GKKGIDDLERTQKGEPPQVFPHPIANNCIPHIDSFTPSGYTKEELKMINETKKIMKDDSIKVSPTTVRVPVVNSHSESVN
VEFARPYEMKELIEILKNAPGVVVMDDPEHNLYPLATFATGKDEVFVGRIRRDETVYSGVNMWIVADNIRKGAATNAVQI
AELVIKNM

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=34.4213649851632, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1789841, Length=354, Percent_Identity=26.271186440678, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320362, Length=382, Percent_Identity=30.3664921465969, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36578; Mature: 36446

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVNVAIVGATGMVGRTFLKVMEERNFPVNKLYLFASSKSAGEKLYFKNKEYIVEELTEE
CCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHH
SFNRDIQIALFSAGATVSKQFAPIAASRGIVVIDNSSAWRMDENVPLVVPEVNPEDISWH
HCCCCEEEEEEECCCCCCHHCCCCCCCCCEEEEECCCCEEECCCCCEEEECCCCCCCCCC
KGIIANPNCSTIQMVVPLKPLHDKYRIKRIVVSTYQAVSGAGKKGIDDLERTQKGEPPQV
CCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCC
FPHPIANNCIPHIDSFTPSGYTKEELKMINETKKIMKDDSIKVSPTTVRVPVVNSHSESV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCCCEE
NVEFARPYEMKELIEILKNAPGVVVMDDPEHNLYPLATFATGKDEVFVGRIRRDETVYSG
EEEEECCCCHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCEEEEEECCCCEEECC
VNMWIVADNIRKGAATNAVQIAELVIKNM
CEEEEEECCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
GVNVAIVGATGMVGRTFLKVMEERNFPVNKLYLFASSKSAGEKLYFKNKEYIVEELTEE
CCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEECCHHHHHHHHHHH
SFNRDIQIALFSAGATVSKQFAPIAASRGIVVIDNSSAWRMDENVPLVVPEVNPEDISWH
HCCCCEEEEEEECCCCCCHHCCCCCCCCCEEEEECCCCEEECCCCCEEEECCCCCCCCCC
KGIIANPNCSTIQMVVPLKPLHDKYRIKRIVVSTYQAVSGAGKKGIDDLERTQKGEPPQV
CCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCC
FPHPIANNCIPHIDSFTPSGYTKEELKMINETKKIMKDDSIKVSPTTVRVPVVNSHSESV
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCCCEE
NVEFARPYEMKELIEILKNAPGVVVMDDPEHNLYPLATFATGKDEVFVGRIRRDETVYSG
EEEEECCCCHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCEEEEEECCCCEEECC
VNMWIVADNIRKGAATNAVQIAELVIKNM
CEEEEEECCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]