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The map label for this gene is PotE2 [H]

Identifier: 20807215

GI number: 20807215

Start: 731017

End: 732396

Strand: Reverse

Name: PotE2 [H]

Synonym: TTE0728

Alternate gene names: 20807215

Gene position: 732396-731017 (Counterclockwise)

Preceding gene: 20807216

Following gene: 20807182

Centisome position: 27.23

GC content: 41.74

Gene sequence:

>1380_bases
ATGAATTTATTTCGAAAAAAATCTGTAGATCAACTTCTGGAAGCAGCTGAAAAAACAGGACTTAATAAAAAATTAACCGC
AATAGACCTGGCAGCTTTAGCAATAGGCTCTGTCGTTGGAACGGGAATTTTTGTGTCAACAGGTGAAGGAGCATTAAGAG
CAGGGCCTGGAGTAATTATTTCTTACATCATTGGAGGTATAACTGCTGCTCTAGCTGCTTTCATATTTGCAGAGCTTGTG
ACAATGTTTCCCGTCGCCGGAAGTACCTACACCTACTCTTATGTAGCTTTTGGAGAATTAATAGCCTGGATAATTGGCTG
GGACTTGCTTTTAGAGTACCTTGTTTCAGCAAGCGCCGTTGCATCTGGATGGTCAGGAACTTTTGTAGGACTGCTCAAAT
CTTTCGGCATAACTTTGCCAGAAGCCATAACTAAACCTCCTATATCGGGAGGAATAATGGATTTACCAGCCATTTTAATT
ACCGCTTTTGTGGCGTGGATTTTGTACATTGGTGTAAGGGAAAGCGCAACCACAAACAATATAATAGTTCTCGTAAAAAT
AGGAGTCATCTTGCTTTTCCTGTTCCTCGGTTTCAGCCACGTAAAACTTTCAAACCTTACTCCCTTCGCCCCCTATGGTT
GGAAAGGAATAATGTCTGCTGCTGCAATAATCTTCTTTGCATATATAGGATTTGACGCAGTGTCAACGGCAGCAGAAGAA
ACTAAAAACCCTACGAGGGATGTGCCTTTAGGCCTTGTAATGGCAATGGTAGTGATACTTGCCCTTTACATTTCTGTGGC
AGTTGTATTGGTCGGGATGGTGCCTTATAAAACCATAATTCCTGACAATGCTCTCCCTGGAGCCTTAATGAGCATAGGAA
TCAACTGGGGTTCTGCTTTAGTTGCAACAGGCGCTGCTGTCGGTATGATTTCAACTTTATTGATAACACTCTACGGCCAG
ATACGAATTTTCATGGTTATGGCAAGAGATGGACTTTTGCCTGAGGTGTTTTCCCACATTCATCCAAAATACAGGACACC
CCATATAAATACCGTAATAACGAGTTTGGTAGCAGCTATAATTGCTGGCTTCCTGCCTTTAGACATCATAATTGAGCTCT
GCAACATAGGAACTCTATCTGTCTTTGTAATTGTCTCAATAGGAATACTTGTCCTAAGGGTTAAAATGCCTAATGTAGAG
AGAAAGTTCAGAGTCCCTGCAGTATGGTTAGTCGCACCTCTTACAGCAGCTTTTAGCCTCTATTTAATGGCAAGCCTTCC
ATGGGTGACATGGCTAAGATTTGGCATATGGATGCTGGTCGGCCTTATCATTTACTTTGCTTACGGAAGGTATCATAGCG
TTTTAAATGTGCAAAAATAA

Upstream 100 bases:

>100_bases
CTTTTAAAAGAAAGAGAAAGGGGGTAGACAAGGGAGAAATTTTTTGATAAAATATTCGCTTGTGTGAATAAAAAATCAAT
ATTATAGGGGGATCAAGAGA

Downstream 100 bases:

>100_bases
AGGGAGCTAATCGGCTCCCTTTATTTTTTATACCCTTTAAGCCCGGGGATTTTTCTTTTTACCATTTCTGTGACTATAAA
AGTCGCTACATGGTCTGCAA

Product: amino acid transporters

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MNLFRKKSVDQLLEAAEKTGLNKKLTAIDLAALAIGSVVGTGIFVSTGEGALRAGPGVIISYIIGGITAALAAFIFAELV
TMFPVAGSTYTYSYVAFGELIAWIIGWDLLLEYLVSASAVASGWSGTFVGLLKSFGITLPEAITKPPISGGIMDLPAILI
TAFVAWILYIGVRESATTNNIIVLVKIGVILLFLFLGFSHVKLSNLTPFAPYGWKGIMSAAAIIFFAYIGFDAVSTAAEE
TKNPTRDVPLGLVMAMVVILALYISVAVVLVGMVPYKTIIPDNALPGALMSIGINWGSALVATGAAVGMISTLLITLYGQ
IRIFMVMARDGLLPEVFSHIHPKYRTPHINTVITSLVAAIIAGFLPLDIIIELCNIGTLSVFVIVSIGILVLRVKMPNVE
RKFRVPAVWLVAPLTAAFSLYLMASLPWVTWLRFGIWMLVGLIIYFAYGRYHSVLNVQK

Sequences:

>Translated_459_residues
MNLFRKKSVDQLLEAAEKTGLNKKLTAIDLAALAIGSVVGTGIFVSTGEGALRAGPGVIISYIIGGITAALAAFIFAELV
TMFPVAGSTYTYSYVAFGELIAWIIGWDLLLEYLVSASAVASGWSGTFVGLLKSFGITLPEAITKPPISGGIMDLPAILI
TAFVAWILYIGVRESATTNNIIVLVKIGVILLFLFLGFSHVKLSNLTPFAPYGWKGIMSAAAIIFFAYIGFDAVSTAAEE
TKNPTRDVPLGLVMAMVVILALYISVAVVLVGMVPYKTIIPDNALPGALMSIGINWGSALVATGAAVGMISTLLITLYGQ
IRIFMVMARDGLLPEVFSHIHPKYRTPHINTVITSLVAAIIAGFLPLDIIIELCNIGTLSVFVIVSIGILVLRVKMPNVE
RKFRVPAVWLVAPLTAAFSLYLMASLPWVTWLRFGIWMLVGLIIYFAYGRYHSVLNVQK
>Mature_459_residues
MNLFRKKSVDQLLEAAEKTGLNKKLTAIDLAALAIGSVVGTGIFVSTGEGALRAGPGVIISYIIGGITAALAAFIFAELV
TMFPVAGSTYTYSYVAFGELIAWIIGWDLLLEYLVSASAVASGWSGTFVGLLKSFGITLPEAITKPPISGGIMDLPAILI
TAFVAWILYIGVRESATTNNIIVLVKIGVILLFLFLGFSHVKLSNLTPFAPYGWKGIMSAAAIIFFAYIGFDAVSTAAEE
TKNPTRDVPLGLVMAMVVILALYISVAVVLVGMVPYKTIIPDNALPGALMSIGINWGSALVATGAAVGMISTLLITLYGQ
IRIFMVMARDGLLPEVFSHIHPKYRTPHINTVITSLVAAIIAGFLPLDIIIELCNIGTLSVFVIVSIGILVLRVKMPNVE
RKFRVPAVWLVAPLTAAFSLYLMASLPWVTWLRFGIWMLVGLIIYFAYGRYHSVLNVQK

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI114326544, Length=437, Percent_Identity=31.5789473684211, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI114326550, Length=437, Percent_Identity=31.5789473684211, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI258614005, Length=428, Percent_Identity=33.411214953271, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI258614003, Length=428, Percent_Identity=33.411214953271, Blast_Score=216, Evalue=5e-56,
Organism=Homo sapiens, GI4507047, Length=438, Percent_Identity=31.7351598173516, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI181337167, Length=409, Percent_Identity=35.4523227383863, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI258645169, Length=428, Percent_Identity=32.7102803738318, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI110347453, Length=403, Percent_Identity=33.9950372208437, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI115648063, Length=402, Percent_Identity=26.3681592039801, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI115648022, Length=402, Percent_Identity=26.3681592039801, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI187423910, Length=466, Percent_Identity=23.3905579399142, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI7657591, Length=466, Percent_Identity=23.3905579399142, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI186910308, Length=399, Percent_Identity=24.812030075188, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI186910306, Length=399, Percent_Identity=24.812030075188, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI186910304, Length=399, Percent_Identity=24.812030075188, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI71979932, Length=462, Percent_Identity=24.8917748917749, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI7657683, Length=373, Percent_Identity=24.1286863270777, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI33286428, Length=455, Percent_Identity=24.1758241758242, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI87081869, Length=418, Percent_Identity=24.6411483253589, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI87082023, Length=400, Percent_Identity=22.75, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082250, Length=425, Percent_Identity=25.8823529411765, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786302, Length=348, Percent_Identity=26.4367816091954, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788480, Length=352, Percent_Identity=25.8522727272727, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786789, Length=428, Percent_Identity=22.6635514018692, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786602, Length=416, Percent_Identity=23.5576923076923, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790653, Length=442, Percent_Identity=21.4932126696833, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789017, Length=447, Percent_Identity=21.0290827740492, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081915, Length=441, Percent_Identity=24.2630385487528, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994972, Length=334, Percent_Identity=23.3532934131737, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786694, Length=325, Percent_Identity=24, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=445, Percent_Identity=32.8089887640449, Blast_Score=221, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI17533459, Length=414, Percent_Identity=34.2995169082126, Blast_Score=208, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17531343, Length=410, Percent_Identity=33.1707317073171, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17540018, Length=414, Percent_Identity=26.8115942028986, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17568033, Length=439, Percent_Identity=25.9681093394077, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32566699, Length=471, Percent_Identity=26.5392781316348, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982612, Length=412, Percent_Identity=22.0873786407767, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71982608, Length=412, Percent_Identity=22.0873786407767, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193208714, Length=385, Percent_Identity=22.0779220779221, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32566695, Length=385, Percent_Identity=22.0779220779221, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321053, Length=341, Percent_Identity=25.2199413489736, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24667468, Length=420, Percent_Identity=36.9047619047619, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI221512776, Length=425, Percent_Identity=33.6470588235294, Blast_Score=231, Evalue=9e-61,
Organism=Drosophila melanogaster, GI24666159, Length=425, Percent_Identity=33.6470588235294, Blast_Score=231, Evalue=9e-61,
Organism=Drosophila melanogaster, GI24668806, Length=434, Percent_Identity=33.4101382488479, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI21356285, Length=434, Percent_Identity=33.4101382488479, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24668802, Length=434, Percent_Identity=33.4101382488479, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI161077963, Length=407, Percent_Identity=35.8722358722359, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI281366235, Length=409, Percent_Identity=31.7848410757946, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI116007820, Length=409, Percent_Identity=31.7848410757946, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI116007818, Length=414, Percent_Identity=31.4009661835749, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI85725152, Length=414, Percent_Identity=31.4009661835749, Blast_Score=171, Evalue=9e-43,
Organism=Drosophila melanogaster, GI21357367, Length=414, Percent_Identity=22.9468599033816, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45550968, Length=455, Percent_Identity=25.2747252747253, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19921172, Length=455, Percent_Identity=25.2747252747253, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI221331183, Length=411, Percent_Identity=25.5474452554745, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17647653, Length=411, Percent_Identity=25.5474452554745, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24664379, Length=411, Percent_Identity=25.5474452554745, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24651635, Length=415, Percent_Identity=23.6144578313253, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24651633, Length=415, Percent_Identity=23.6144578313253, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641993, Length=448, Percent_Identity=24.1071428571429, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641995, Length=451, Percent_Identity=23.9467849223947, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49266; Mature: 49266

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFRKKSVDQLLEAAEKTGLNKKLTAIDLAALAIGSVVGTGIFVSTGEGALRAGPGVII
CCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHH
SYIIGGITAALAAFIFAELVTMFPVAGSTYTYSYVAFGELIAWIIGWDLLLEYLVSASAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGWSGTFVGLLKSFGITLPEAITKPPISGGIMDLPAILITAFVAWILYIGVRESATTNN
HCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IIVLVKIGVILLFLFLGFSHVKLSNLTPFAPYGWKGIMSAAAIIFFAYIGFDAVSTAAEE
EEEHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKNPTRDVPLGLVMAMVVILALYISVAVVLVGMVPYKTIIPDNALPGALMSIGINWGSAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHCCCCCHHH
VATGAAVGMISTLLITLYGQIRIFMVMARDGLLPEVFSHIHPKYRTPHINTVITSLVAAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHH
IAGFLPLDIIIELCNIGTLSVFVIVSIGILVLRVKMPNVERKFRVPAVWLVAPLTAAFSL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCHHHCCCHHHHHHHHHHHHHH
YLMASLPWVTWLRFGIWMLVGLIIYFAYGRYHSVLNVQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLFRKKSVDQLLEAAEKTGLNKKLTAIDLAALAIGSVVGTGIFVSTGEGALRAGPGVII
CCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHH
SYIIGGITAALAAFIFAELVTMFPVAGSTYTYSYVAFGELIAWIIGWDLLLEYLVSASAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGWSGTFVGLLKSFGITLPEAITKPPISGGIMDLPAILITAFVAWILYIGVRESATTNN
HCCCCHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IIVLVKIGVILLFLFLGFSHVKLSNLTPFAPYGWKGIMSAAAIIFFAYIGFDAVSTAAEE
EEEHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKNPTRDVPLGLVMAMVVILALYISVAVVLVGMVPYKTIIPDNALPGALMSIGINWGSAL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHCCCCCHHH
VATGAAVGMISTLLITLYGQIRIFMVMARDGLLPEVFSHIHPKYRTPHINTVITSLVAAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHH
IAGFLPLDIIIELCNIGTLSVFVIVSIGILVLRVKMPNVERKFRVPAVWLVAPLTAAFSL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEECCCCCHHHCCCHHHHHHHHHHHHHH
YLMASLPWVTWLRFGIWMLVGLIIYFAYGRYHSVLNVQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]