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The map label for this gene is Pcp [H]

Identifier: 20807167

GI number: 20807167

Start: 681710

End: 682321

Strand: Direct

Name: Pcp [H]

Synonym: TTE0678

Alternate gene names: 20807167

Gene position: 681710-682321 (Clockwise)

Preceding gene: 20807166

Following gene: 20807168

Centisome position: 25.35

GC content: 36.44

Gene sequence:

>612_bases
ATGAAAATTCTTGTTACGGCTTTTGACCCTTTTGGAGGGGAGAGTGTCAATCCTTCTTATGAGGTGTTAAAGAATTTGAA
AGATAATATAGAAGGAGCGGAAATAATAAAACTTCAAGTTCCCACTGCTTTTTATGTTTCTGTGGAAAAAGCAATAGAAA
AGATAAAGGAAGTTAATCCTGATGCGGTTTTAAGCATTGGGCAGGCTGGTGGACGATATGATATAAGTGTCGAGAGGGTA
GCTATCAATATTGATGATGCTAGAATTCCTGATAATATGGGGCAGCAGCCAATTGACATCCCGATTGACCCTGAAGGACC
TCCAGCGTATTTTGCTACTATTCCAATAAAGGAAATAGTAGAAGCGATAAAAAAAGAAAACCTACCAGCATCTGTTTCTA
ATTCTGCAGGTACCTATGTGTGCAATCATCTAATGTACGGAATTCTAAATTACATCCATAAAAACAAATTGAACATTAAA
GCAGGGTTTATTCATATACCTTATTTACCAGAACAAGTTCTAGAAAAGCCTAATACTCCTTATATGTCTTTAAGTGATAT
GGTAAAAGCTATAGAGACGGCCATAAAGGTGATTGTAAAAGCAATGGCATAG

Upstream 100 bases:

>100_bases
ATTTAAAGCATGGTTTAAAAAGATATTAATGGCAAGGATGCCAGAAGAAGAGAGAAAGAATATGGAGAGAATAATAGATG
AAAATGAGGAGGTAGAAACT

Downstream 100 bases:

>100_bases
AAAAAATTTTGTTTTACGGTTCAAACTTGTTAAAATAGAGTTAAATAAAAAAGAATGAGGGGAGAGGAATGGGGGCTCTT
GTCCTTCTTGTAGGGCTTCC

Product: pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase 2; Pyroglutamyl-peptidase I 2; PGP-I 2; Pyrase 2 [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKILVTAFDPFGGESVNPSYEVLKNLKDNIEGAEIIKLQVPTAFYVSVEKAIEKIKEVNPDAVLSIGQAGGRYDISVERV
AINIDDARIPDNMGQQPIDIPIDPEGPPAYFATIPIKEIVEAIKKENLPASVSNSAGTYVCNHLMYGILNYIHKNKLNIK
AGFIHIPYLPEQVLEKPNTPYMSLSDMVKAIETAIKVIVKAMA

Sequences:

>Translated_203_residues
MKILVTAFDPFGGESVNPSYEVLKNLKDNIEGAEIIKLQVPTAFYVSVEKAIEKIKEVNPDAVLSIGQAGGRYDISVERV
AINIDDARIPDNMGQQPIDIPIDPEGPPAYFATIPIKEIVEAIKKENLPASVSNSAGTYVCNHLMYGILNYIHKNKLNIK
AGFIHIPYLPEQVLEKPNTPYMSLSDMVKAIETAIKVIVKAMA
>Mature_203_residues
MKILVTAFDPFGGESVNPSYEVLKNLKDNIEGAEIIKLQVPTAFYVSVEKAIEKIKEVNPDAVLSIGQAGGRYDISVERV
AINIDDARIPDNMGQQPIDIPIDPEGPPAYFATIPIKEIVEAIKKENLPASVSNSAGTYVCNHLMYGILNYIHKNKLNIK
AGFIHIPYLPEQVLEKPNTPYMSLSDMVKAIETAIKVIVKAMA

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 22307; Mature: 22307

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS01333 PYRASE_GLU ; PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVTAFDPFGGESVNPSYEVLKNLKDNIEGAEIIKLQVPTAFYVSVEKAIEKIKEVNP
CEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
DAVLSIGQAGGRYDISVERVAINIDDARIPDNMGQQPIDIPIDPEGPPAYFATIPIKEIV
HHEEEECCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHH
EAIKKENLPASVSNSAGTYVCNHLMYGILNYIHKNKLNIKAGFIHIPYLPEQVLEKPNTP
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHCCCCCC
YMSLSDMVKAIETAIKVIVKAMA
CCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKILVTAFDPFGGESVNPSYEVLKNLKDNIEGAEIIKLQVPTAFYVSVEKAIEKIKEVNP
CEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
DAVLSIGQAGGRYDISVERVAINIDDARIPDNMGQQPIDIPIDPEGPPAYFATIPIKEIV
HHEEEECCCCCEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHHHH
EAIKKENLPASVSNSAGTYVCNHLMYGILNYIHKNKLNIKAGFIHIPYLPEQVLEKPNTP
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHCCCCCC
YMSLSDMVKAIETAIKVIVKAMA
CCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]