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The map label for this gene is yggV [C]

Identifier: 20807114

GI number: 20807114

Start: 625335

End: 625937

Strand: Direct

Name: yggV [C]

Synonym: TTE0620

Alternate gene names: 20807114

Gene position: 625335-625937 (Clockwise)

Preceding gene: 20807113

Following gene: 20807115

Centisome position: 23.25

GC content: 37.31

Gene sequence:

>603_bases
ATGTTGAGGTTGATAGTGGCAACTCACAATCCCAACAAGGCTAAAGAGATAAAAGACTTTTTTAAAGGTTACCCTGTGGA
AGTAGTCTCAATGAAAGAATTGGGAATAGAAGAAGATATTGAAGAATATGGCAATACAATCGAAGAAAACGCCCTTATAA
AAGCGAGATTTTTAAGGGACAAAGTAAAAGAAGGAATTGTCATTTCAGACGACACAGGGCTTTTTGTGGAATATTTAGGA
GGACAGCCAGGTGTGTATTCTGCTAGATTTGCAGGAGAAAATGCAACTTATGAGGAGAATAACAGGAAATTATTGAAATT
GCTTGAAGGTGTGCCTTATGAGAAAAGAAAGGCTTATTTTAAAACGATTATTGCTGTAATAGAGGGTGAAAAAGAAGTCC
TCTTAGAAGGGGTTTTAGAGGGCCATATTTTGGATCATTTGCAGGGGGAAAACGGGTTTGGATATGACCCCGTCTTTTTT
GTGGATGGGATAGGTAAGACCCTTGCGGAGCTTTCATTAGAGGAAAAGAATAAAATAAGTCATAGAGGAAAGGCGCTTTT
AAAGCTTAAAGAATACATCTTAAAAAGGCTGGAGGAAAATTAA

Upstream 100 bases:

>100_bases
TTTGAGGAGCTTTTGGATTTAGCTGCTCATGGCATTGAACAGATTATCAAGATACAGAAAGAAGTGCTCTCAGACATTGC
TGACAAAATAGGGGTGGAGA

Downstream 100 bases:

>100_bases
AATGGTTGTAGCAGTGATAAGCGATACACACGGCATATTCACACTGGTGAGGAATAAATTAAAGGAATTTAAAGGCTTAG
ATTATATATTTCACTTGGGA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MLRLIVATHNPNKAKEIKDFFKGYPVEVVSMKELGIEEDIEEYGNTIEENALIKARFLRDKVKEGIVISDDTGLFVEYLG
GQPGVYSARFAGENATYEENNRKLLKLLEGVPYEKRKAYFKTIIAVIEGEKEVLLEGVLEGHILDHLQGENGFGYDPVFF
VDGIGKTLAELSLEEKNKISHRGKALLKLKEYILKRLEEN

Sequences:

>Translated_200_residues
MLRLIVATHNPNKAKEIKDFFKGYPVEVVSMKELGIEEDIEEYGNTIEENALIKARFLRDKVKEGIVISDDTGLFVEYLG
GQPGVYSARFAGENATYEENNRKLLKLLEGVPYEKRKAYFKTIIAVIEGEKEVLLEGVLEGHILDHLQGENGFGYDPVFF
VDGIGKTLAELSLEEKNKISHRGKALLKLKEYILKRLEEN
>Mature_200_residues
MLRLIVATHNPNKAKEIKDFFKGYPVEVVSMKELGIEEDIEEYGNTIEENALIKARFLRDKVKEGIVISDDTGLFVEYLG
GQPGVYSARFAGENATYEENNRKLLKLLEGVPYEKRKAYFKTIIAVIEGEKEVLLEGVLEGHILDHLQGENGFGYDPVFF
VDGIGKTLAELSLEEKNKISHRGKALLKLKEYILKRLEEN

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=195, Percent_Identity=31.2820512820513, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI31657144, Length=173, Percent_Identity=32.9479768786127, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1789324, Length=189, Percent_Identity=41.7989417989418, Blast_Score=147, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17556833, Length=188, Percent_Identity=34.0425531914894, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6322529, Length=131, Percent_Identity=34.3511450381679, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19920712, Length=176, Percent_Identity=33.5227272727273, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_THETN (Q8RC29)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622285.1
- ProteinModelPortal:   Q8RC29
- SMR:   Q8RC29
- GeneID:   996546
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0620
- NMPDR:   fig|273068.3.peg.203
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- ProtClustDB:   PRK00120
- BioCyc:   TTEN273068:TTE0620-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 22691; Mature: 22691

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRLIVATHNPNKAKEIKDFFKGYPVEVVSMKELGIEEDIEEYGNTIEENALIKARFLRD
CEEEEEEECCCCHHHHHHHHHCCCCEEEEEHHHCCCHHHHHHHCCHHHHHHHHHHHHHHH
KVKEGIVISDDTGLFVEYLGGQPGVYSARFAGENATYEENNRKLLKLLEGVPYEKRKAYF
HHHCCEEEECCCCEEHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHH
KTIIAVIEGEKEVLLEGVLEGHILDHLQGENGFGYDPVFFVDGIGKTLAELSLEEKNKIS
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
HRGKALLKLKEYILKRLEEN
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLRLIVATHNPNKAKEIKDFFKGYPVEVVSMKELGIEEDIEEYGNTIEENALIKARFLRD
CEEEEEEECCCCHHHHHHHHHCCCCEEEEEHHHCCCHHHHHHHCCHHHHHHHHHHHHHHH
KVKEGIVISDDTGLFVEYLGGQPGVYSARFAGENATYEENNRKLLKLLEGVPYEKRKAYF
HHHCCEEEECCCCEEHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCCCCHHHHHHH
KTIIAVIEGEKEVLLEGVLEGHILDHLQGENGFGYDPVFFVDGIGKTLAELSLEEKNKIS
HHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
HRGKALLKLKEYILKRLEEN
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336