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The map label for this gene is CelB2 [H]

Identifier: 20807096

GI number: 20807096

Start: 603369

End: 604679

Strand: Direct

Name: CelB2 [H]

Synonym: TTE0601

Alternate gene names: 20807096

Gene position: 603369-604679 (Clockwise)

Preceding gene: 20807095

Following gene: 20807097

Centisome position: 22.43

GC content: 39.59

Gene sequence:

>1311_bases
ATGAGTGACAGAATTTCAAACAATCCGTTTATGAAGTGGATGGAAGAATCATTAATGCCGGTATTAGCTAGAATAGCTCA
AAACGTGTACTTGCAGTCAATTAGAGATGCATTTTCGAGTTTTGCTTTGCCTGTGATTTTGACCGGAGCTCTTTTCCTCA
TAATAGCAAATCCACCAGAAGGAATTAATTGGGCTCCAATACACGCGTGGGCCAAAGCAGTAAAGCCCATTGCAGCCCAA
ATCATGATACCTTTTCAACTTACTTTTGGAATAATGGCTATGATGGTGGCTTTTGGTACAGCTTATAGTCTCGCTGCCAG
ATGGGATTTGGATGAGACAATGACTGGAATAATTGCACTTCTAGCTTTCTTTATAACAAGTTTTCCTGCAACAGATGTGA
CGAAGGTTACTTTTGGAGATGTTTTAAATTACTTGGGTGGACAAGGGTTATTCGTAGCAATAATAATAGGAATATTAAGC
GCAATAGTAGTGAGATTTTTCAATAGAAAAGGATTAGTAATTAAAATGCCTGAAGGAGTACCGCCTTATGTAGTGAGAAG
CTTTTTAGCATTAATTCCAATGTTTGTAATGGTGGTATCTGCATGGCTTGTAGAGTGGTTTGTGTGGTCGAGATTCCACA
TAACATTACCTCAATTAGTGCTTGATTTGTTCAAACCACTTGTTACAGCATCAAACACTTATCCAGCAGCCTTAGCAGAG
ATAATATTGATGATGCTTTTGTGGTCATTAGGAATTCATGGAATGAACGTAGTATCATCAATCGCGTATCCTTTCTGGAT
GACTCAGCTAGCGGCTAATGCAGAAGCGGCTTCTCGTGGCTTGCCGTTGCCAGGCATTGTGACAGAACCTTTCTTCCATG
TATTTACTCACTTAGGTGGGTCAGGAACTACATGGCCTTTGACGATAATGTTTTTGCTTTCTGCTTCCATGCAGCTTAGA
ACAATTGGGCGAGCTGAACTTATACCTGCAATATTTAACATAAACGAACCTATAATCTTTGGCGCACCTATTGTATTAAA
CCCAATACTCATCATTCCATTTATTCTGGCTCCTGCAGCTGTTGTGACAATAAACTACTTTGCTTTTGCGCTAAATTTAG
TGCCAAGACCTCTGATACAGTTGCCTTTTACAGTCCCAGTGTTTATAAGTGGATTTATATCTTCTGGAGGGCACTGGCAG
GGAGCCTTGCTGCAATTGGTAGACCTCATTGTAGCGGCGATTATATACTATCCTTTCTTTAGGATGTATGAAGCACAACT
TTTAAAAAATGAAAGAGAAGTAGAAAAATGA

Upstream 100 bases:

>100_bases
GGACATGCAGGCTTTTGCCATGATGGATGGCAAAAAAATATTAAATCAAATAATCGAACTTGCCAAAAAAGCAGGAAAAG
AAGTATAAGGAGGGAACAGG

Downstream 100 bases:

>100_bases
TTGAAATGGGAGTGACTGCAATGGATTTGGAACAGATAATATACAATTTAGTGCTGCATGGAGGAAATGCAAGAGCAGAA
GCATATGAGGCATTGGATGC

Product: phosphotransferase system cellobiose-specific component IIC

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: Putative PTS system EIIC component [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSDRISNNPFMKWMEESLMPVLARIAQNVYLQSIRDAFSSFALPVILTGALFLIIANPPEGINWAPIHAWAKAVKPIAAQ
IMIPFQLTFGIMAMMVAFGTAYSLAARWDLDETMTGIIALLAFFITSFPATDVTKVTFGDVLNYLGGQGLFVAIIIGILS
AIVVRFFNRKGLVIKMPEGVPPYVVRSFLALIPMFVMVVSAWLVEWFVWSRFHITLPQLVLDLFKPLVTASNTYPAALAE
IILMMLLWSLGIHGMNVVSSIAYPFWMTQLAANAEAASRGLPLPGIVTEPFFHVFTHLGGSGTTWPLTIMFLLSASMQLR
TIGRAELIPAIFNINEPIIFGAPIVLNPILIIPFILAPAAVVTINYFAFALNLVPRPLIQLPFTVPVFISGFISSGGHWQ
GALLQLVDLIVAAIIYYPFFRMYEAQLLKNEREVEK

Sequences:

>Translated_436_residues
MSDRISNNPFMKWMEESLMPVLARIAQNVYLQSIRDAFSSFALPVILTGALFLIIANPPEGINWAPIHAWAKAVKPIAAQ
IMIPFQLTFGIMAMMVAFGTAYSLAARWDLDETMTGIIALLAFFITSFPATDVTKVTFGDVLNYLGGQGLFVAIIIGILS
AIVVRFFNRKGLVIKMPEGVPPYVVRSFLALIPMFVMVVSAWLVEWFVWSRFHITLPQLVLDLFKPLVTASNTYPAALAE
IILMMLLWSLGIHGMNVVSSIAYPFWMTQLAANAEAASRGLPLPGIVTEPFFHVFTHLGGSGTTWPLTIMFLLSASMQLR
TIGRAELIPAIFNINEPIIFGAPIVLNPILIIPFILAPAAVVTINYFAFALNLVPRPLIQLPFTVPVFISGFISSGGHWQ
GALLQLVDLIVAAIIYYPFFRMYEAQLLKNEREVEK
>Mature_435_residues
SDRISNNPFMKWMEESLMPVLARIAQNVYLQSIRDAFSSFALPVILTGALFLIIANPPEGINWAPIHAWAKAVKPIAAQI
MIPFQLTFGIMAMMVAFGTAYSLAARWDLDETMTGIIALLAFFITSFPATDVTKVTFGDVLNYLGGQGLFVAIIIGILSA
IVVRFFNRKGLVIKMPEGVPPYVVRSFLALIPMFVMVVSAWLVEWFVWSRFHITLPQLVLDLFKPLVTASNTYPAALAEI
ILMMLLWSLGIHGMNVVSSIAYPFWMTQLAANAEAASRGLPLPGIVTEPFFHVFTHLGGSGTTWPLTIMFLLSASMQLRT
IGRAELIPAIFNINEPIIFGAPIVLNPILIIPFILAPAAVVTINYFAFALNLVPRPLIQLPFTVPVFISGFISSGGHWQG
ALLQLVDLIVAAIIYYPFFRMYEAQLLKNEREVEK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane [H]

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=452, Percent_Identity=29.2035398230088, Blast_Score=155, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 48252; Mature: 48121

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDRISNNPFMKWMEESLMPVLARIAQNVYLQSIRDAFSSFALPVILTGALFLIIANPPE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC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HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]