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The map label for this gene is MurI2

Identifier: 20807090

GI number: 20807090

Start: 596611

End: 597405

Strand: Direct

Name: MurI2

Synonym: TTE0595

Alternate gene names: 20807090

Gene position: 596611-597405 (Clockwise)

Preceding gene: 20807089

Following gene: 20807091

Centisome position: 22.18

GC content: 36.6

Gene sequence:

>795_bases
ATGGATTCAAGACCTATAGGAGTTTTTGATTCAGGAGTAGGAGGTTTGACTGTATTAAAAAGACTTATTCAGGTTTTGCC
CGAGGAGGATTATATTTATTTTGGCGACACAAAAAGGGTTCCCTATGGAGATAGAAGTAAAGAAGAAATAGAGCTTTTTG
CAGGTCAGATCATAAACTTTATGAAAGAAAAAAATGTAAAGGCGGTTGTGATAGCCTGCAATACTACGTGTGCGACTATT
GACAAAGGAAAGTATGACATTGAACTTTTTGACGTATTAAAAGCTGGCGCAGAAAGCGGAGTTTATTGTACAAAAAATAA
AAAAGTTGGAGTTATTGCTACGAAGAGGACGGTAGAGAGCAGAAGCTACGAAATCAATATAAAGAGCATAAATCCTCAAA
TTGAAGTTTACCAGAAAGCCTGTCCTGAATTTGTGCCTTTGATTGAAAAAGGCCTTTACAATTCGCATTTAGCTTATAAA
GCTGCTAAAGATTGCCTTGAGGAGTTTAAAGGGAAAGAAATAGATACTCTCATACTTGGTTGTACCCATTATCCTTTGAT
GGAACCGATTATAAAGGCCATCATGGGAGATGGGGTTAAGGTGGTGGACCCAGCTGTAAGGTTGTCCCATGAAGTGAAAG
AATATCTAGAAAGAAGCAGGATTTTAAATTTTGGTAAGAAAGGCAAAATAGAGTTTTTTGTAAGTGGCGATGCTGAAAAT
TTTAAAAGGGCCGCCGAAATGGTGCTCGGTAAAAAAATTGATGAAGTATTTATTGTGGATATTGAAAGATATTAA

Upstream 100 bases:

>100_bases
TAAGAAAAAATTTTGAAGGTGTGAAAGTGGTAGAATTGAGCAAGAGAGTTTCTCTTTACATATTGAAACCTTACAAAGAT
TTAAATTAGGGTGTGGTGGA

Downstream 100 bases:

>100_bases
AAAAGGTGATGGATATGGACATTTTAAAAGAAGTTGAAAAAGTGGAGGAAGAGATAATAGGGATAAGGCGAAAAATACAC
ATGCACCCTGAATTGGGATT

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MDSRPIGVFDSGVGGLTVLKRLIQVLPEEDYIYFGDTKRVPYGDRSKEEIELFAGQIINFMKEKNVKAVVIACNTTCATI
DKGKYDIELFDVLKAGAESGVYCTKNKKVGVIATKRTVESRSYEINIKSINPQIEVYQKACPEFVPLIEKGLYNSHLAYK
AAKDCLEEFKGKEIDTLILGCTHYPLMEPIIKAIMGDGVKVVDPAVRLSHEVKEYLERSRILNFGKKGKIEFFVSGDAEN
FKRAAEMVLGKKIDEVFIVDIERY

Sequences:

>Translated_264_residues
MDSRPIGVFDSGVGGLTVLKRLIQVLPEEDYIYFGDTKRVPYGDRSKEEIELFAGQIINFMKEKNVKAVVIACNTTCATI
DKGKYDIELFDVLKAGAESGVYCTKNKKVGVIATKRTVESRSYEINIKSINPQIEVYQKACPEFVPLIEKGLYNSHLAYK
AAKDCLEEFKGKEIDTLILGCTHYPLMEPIIKAIMGDGVKVVDPAVRLSHEVKEYLERSRILNFGKKGKIEFFVSGDAEN
FKRAAEMVLGKKIDEVFIVDIERY
>Mature_264_residues
MDSRPIGVFDSGVGGLTVLKRLIQVLPEEDYIYFGDTKRVPYGDRSKEEIELFAGQIINFMKEKNVKAVVIACNTTCATI
DKGKYDIELFDVLKAGAESGVYCTKNKKVGVIATKRTVESRSYEINIKSINPQIEVYQKACPEFVPLIEKGLYNSHLAYK
AAKDCLEEFKGKEIDTLILGCTHYPLMEPIIKAIMGDGVKVVDPAVRLSHEVKEYLERSRILNFGKKGKIEFFVSGDAEN
FKRAAEMVLGKKIDEVFIVDIERY

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=227, Percent_Identity=33.0396475770925, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI2_THETN (Q8RC52)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622261.1
- ProteinModelPortal:   Q8RC52
- SMR:   Q8RC52
- GeneID:   996386
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0595
- NMPDR:   fig|273068.3.peg.72
- HOGENOM:   HBG645102
- OMA:   ANEYLEP
- ProtClustDB:   CLSK900684
- BioCyc:   TTEN273068:TTE0595-MONOMER
- BRENDA:   5.1.1.3
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 29724; Mature: 29724

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSRPIGVFDSGVGGLTVLKRLIQVLPEEDYIYFGDTKRVPYGDRSKEEIELFAGQIINF
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
MKEKNVKAVVIACNTTCATIDKGKYDIELFDVLKAGAESGVYCTKNKKVGVIATKRTVES
HHHCCCEEEEEEECCEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCEEEEEEEEEECCC
RSYEINIKSINPQIEVYQKACPEFVPLIEKGLYNSHLAYKAAKDCLEEFKGKEIDTLILG
CEEEEEEEECCCHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
CTHYPLMEPIIKAIMGDGVKVVDPAVRLSHEVKEYLERSRILNFGKKGKIEFFVSGDAEN
CCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHH
FKRAAEMVLGKKIDEVFIVDIERY
HHHHHHHHHHCCCCEEEEEEEECC
>Mature Secondary Structure
MDSRPIGVFDSGVGGLTVLKRLIQVLPEEDYIYFGDTKRVPYGDRSKEEIELFAGQIINF
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
MKEKNVKAVVIACNTTCATIDKGKYDIELFDVLKAGAESGVYCTKNKKVGVIATKRTVES
HHHCCCEEEEEEECCEEEEECCCCCCHHHHHHHHCCCCCCEEEECCCEEEEEEEEEECCC
RSYEINIKSINPQIEVYQKACPEFVPLIEKGLYNSHLAYKAAKDCLEEFKGKEIDTLILG
CEEEEEEEECCCHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEE
CTHYPLMEPIIKAIMGDGVKVVDPAVRLSHEVKEYLERSRILNFGKKGKIEFFVSGDAEN
CCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHH
FKRAAEMVLGKKIDEVFIVDIERY
HHHHHHHHHHCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336