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The map label for this gene is ZnuB [H]

Identifier: 20806876

GI number: 20806876

Start: 387763

End: 388554

Strand: Reverse

Name: ZnuB [H]

Synonym: TTE0361

Alternate gene names: 20806876

Gene position: 388554-387763 (Counterclockwise)

Preceding gene: 20806877

Following gene: 20806863

Centisome position: 14.45

GC content: 39.27

Gene sequence:

>792_bases
ATGTTTGACATTTTTTCTTACGAATTTATGAGGAGAGCTTTTATAGCAGGGGCTATAATAGCAGTGATAGCCCCTTTAGT
GGGAAATTTCTTGGTACTAAGAAGGCTTTCCCAAATGGGGCATGCTCTGTCTCATGTGGCTTTAGCGGGAGTAGCAGCTG
GAATTTTGGCCGGCATTGACCCTACTGTAGGCTCAATTGCCATAGTCCTTCTAGCCGCCTTTGGAATAGAAGGACTGAGA
AAAACCTATTTTCAGTATTCTGAGCTTTCAATTGCTATAATTGTATCTGCAGGAATGGCAGTTGCGATAATACTCTTAAA
TTTTGCAAGAGGCGGAGCAGTCAATGTAATGAACTACCTCTTTGGTAGCATTGTATCTGTAACATATACAGATGTTGTGT
TAATTTCCACCTTAGGCCTTTTAGTCATTCTCACTATAGCGCTTTTTTACAAGGAACTTTTGTACATCACTTTTGACGAA
GAAGCTGCCACAATATCAGGATTACCTGTGTCAGCTATAAACTTTCTCTTCACAATTTTAGTAGCTCTAACAGTAGCACT
AGCAATGAGAATTGTAGGAGCGCTTTTGGTGTCGAGCTTAATGGTCACACCCTCTGCCGCCAGTTTAAAAATCGCTCAAA
GCTTTAAACAAGCCATAATCTACTCGATTATCTTCTCCTTTATATCAGTGTTCGCTGGAATTATACTCTCTTTTTACTTC
GATTTATCACCAGGTGGAACAATAATACTCATTTCCCTCGCTATAATGGGAATAACATCGTTAAAAAAATAA

Upstream 100 bases:

>100_bases
GAAGCTATCGATATAGAAAAGCACGACTTTACTTCTTTCCTCTACGAATATCCTGTGAAGAAAGTAAAGCATCAGCATAA
TAATAATGGGAGTGTAGAAC

Downstream 100 bases:

>100_bases
AAGGTGGAGCATAGCGCTCCACTTTAATAATTTTCTAAAAGTTCAATCATGACTTTCAATGCTCTCAAAGTATCTATATA
AGCGTATCTTCCCCCTTCAA

Product: ABC-type Mn2+/Zn2+ transport systems, permease components

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MFDIFSYEFMRRAFIAGAIIAVIAPLVGNFLVLRRLSQMGHALSHVALAGVAAGILAGIDPTVGSIAIVLLAAFGIEGLR
KTYFQYSELSIAIIVSAGMAVAIILLNFARGGAVNVMNYLFGSIVSVTYTDVVLISTLGLLVILTIALFYKELLYITFDE
EAATISGLPVSAINFLFTILVALTVALAMRIVGALLVSSLMVTPSAASLKIAQSFKQAIIYSIIFSFISVFAGIILSFYF
DLSPGGTIILISLAIMGITSLKK

Sequences:

>Translated_263_residues
MFDIFSYEFMRRAFIAGAIIAVIAPLVGNFLVLRRLSQMGHALSHVALAGVAAGILAGIDPTVGSIAIVLLAAFGIEGLR
KTYFQYSELSIAIIVSAGMAVAIILLNFARGGAVNVMNYLFGSIVSVTYTDVVLISTLGLLVILTIALFYKELLYITFDE
EAATISGLPVSAINFLFTILVALTVALAMRIVGALLVSSLMVTPSAASLKIAQSFKQAIIYSIIFSFISVFAGIILSFYF
DLSPGGTIILISLAIMGITSLKK
>Mature_263_residues
MFDIFSYEFMRRAFIAGAIIAVIAPLVGNFLVLRRLSQMGHALSHVALAGVAAGILAGIDPTVGSIAIVLLAAFGIEGLR
KTYFQYSELSIAIIVSAGMAVAIILLNFARGGAVNVMNYLFGSIVSVTYTDVVLISTLGLLVILTIALFYKELLYITFDE
EAATISGLPVSAINFLFTILVALTVALAMRIVGALLVSSLMVTPSAASLKIAQSFKQAIIYSIIFSFISVFAGIILSFYF
DLSPGGTIILISLAIMGITSLKK

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=257, Percent_Identity=28.4046692607004, Blast_Score=117, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 27891; Mature: 27891

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDIFSYEFMRRAFIAGAIIAVIAPLVGNFLVLRRLSQMGHALSHVALAGVAAGILAGID
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTVGSIAIVLLAAFGIEGLRKTYFQYSELSIAIIVSAGMAVAIILLNFARGGAVNVMNYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FGSIVSVTYTDVVLISTLGLLVILTIALFYKELLYITFDEEAATISGLPVSAINFLFTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHH
VALTVALAMRIVGALLVSSLMVTPSAASLKIAQSFKQAIIYSIIFSFISVFAGIILSFYF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLSPGGTIILISLAIMGITSLKK
CCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFDIFSYEFMRRAFIAGAIIAVIAPLVGNFLVLRRLSQMGHALSHVALAGVAAGILAGID
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTVGSIAIVLLAAFGIEGLRKTYFQYSELSIAIIVSAGMAVAIILLNFARGGAVNVMNYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FGSIVSVTYTDVVLISTLGLLVILTIALFYKELLYITFDEEAATISGLPVSAINFLFTIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHH
VALTVALAMRIVGALLVSSLMVTPSAASLKIAQSFKQAIIYSIIFSFISVFAGIILSFYF
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLSPGGTIILISLAIMGITSLKK
CCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]