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The map label for this gene is fabZ [H]

Identifier: 20806701

GI number: 20806701

Start: 178160

End: 178585

Strand: Direct

Name: fabZ [H]

Synonym: TTE0175

Alternate gene names: 20806701

Gene position: 178160-178585 (Clockwise)

Preceding gene: 20806700

Following gene: 20806702

Centisome position: 6.62

GC content: 44.37

Gene sequence:

>426_bases
GTGGAAAATAAAGACATAAGAAAAATTCTTCCCCACAGATACCCTTTTTTGCTAGTAGATAGGATAATAGAGCTTGAAGA
AGGGAAAAGAGCTGTCGGGATAAAGAATGTTACATCTAACGAGCCCTTTTTTCAGGGGCATTTTCCAGACAACCCCATAA
TGCCGGGAGTTTTGATTGTGGAAGCGCTGGCACAGGTGGCAGGGATTGCTGTAATGAATGTAGAAGAGTTTAAAGGGAAG
CTGGGGCTTTTTGCAGGCATTGATAAATGCCGCTTTAAAAAAGTTGTGCGGCCGGGCGACCAGCTCATCTTAGAGGTCTC
AATAGATTCAATTAGGATGGGGTTAGTCAAAGCTAAAGGCGTTGCAAAAGTGGGAGAGGAAATCGCAGCTACTGCTGAAC
TCATGTTTGTGATGGCGGAGGAATAG

Upstream 100 bases:

>100_bases
AAAGGTTTAAAGGGCGAAAAGCCCTTTTTGTTTTTTCTGCAACTTGTGGTATAATCAATATCAACTGAAAGTGTCAATCT
ATAGACGGGGTGAAGGATAA

Downstream 100 bases:

>100_bases
GAGTGGCGGTATGTCTACTGTGAAAAAGACAGTAAAAGCAGCCTCTGTCATAATGGTCTTGACCCTTATAAGCAAAATAT
TTGGTTTTTTTAGAGATGTG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MENKDIRKILPHRYPFLLVDRIIELEEGKRAVGIKNVTSNEPFFQGHFPDNPIMPGVLIVEALAQVAGIAVMNVEEFKGK
LGLFAGIDKCRFKKVVRPGDQLILEVSIDSIRMGLVKAKGVAKVGEEIAATAELMFVMAEE

Sequences:

>Translated_141_residues
MENKDIRKILPHRYPFLLVDRIIELEEGKRAVGIKNVTSNEPFFQGHFPDNPIMPGVLIVEALAQVAGIAVMNVEEFKGK
LGLFAGIDKCRFKKVVRPGDQLILEVSIDSIRMGLVKAKGVAKVGEEIAATAELMFVMAEE
>Mature_141_residues
MENKDIRKILPHRYPFLLVDRIIELEEGKRAVGIKNVTSNEPFFQGHFPDNPIMPGVLIVEALAQVAGIAVMNVEEFKGK
LGLFAGIDKCRFKKVVRPGDQLILEVSIDSIRMGLVKAKGVAKVGEEIAATAELMFVMAEE

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=143, Percent_Identity=50.3496503496504, Blast_Score=144, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 15605; Mature: 15605

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKDIRKILPHRYPFLLVDRIIELEEGKRAVGIKNVTSNEPFFQGHFPDNPIMPGVLIV
CCCCHHHHHCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCEEECCCCCCCCCCHHHHH
EALAQVAGIAVMNVEEFKGKLGLFAGIDKCRFKKVVRPGDQLILEVSIDSIRMGLVKAKG
HHHHHHHCCCEECHHHHHCCHHHHHCCHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCC
VAKVGEEIAATAELMFVMAEE
HHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MENKDIRKILPHRYPFLLVDRIIELEEGKRAVGIKNVTSNEPFFQGHFPDNPIMPGVLIV
CCCCHHHHHCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCEEECCCCCCCCCCHHHHH
EALAQVAGIAVMNVEEFKGKLGLFAGIDKCRFKKVVRPGDQLILEVSIDSIRMGLVKAKG
HHHHHHHCCCEECHHHHHCCHHHHHCCHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCC
VAKVGEEIAATAELMFVMAEE
HHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA