Click here to switch to the map view.

The map label for this gene is WecB [C]

Identifier: 20806681

GI number: 20806681

Start: 151445

End: 152602

Strand: Direct

Name: WecB [C]

Synonym: TTE0155

Alternate gene names: 20806681

Gene position: 151445-152602 (Clockwise)

Preceding gene: 20806680

Following gene: 20806683

Centisome position: 5.63

GC content: 40.76

Gene sequence:

>1158_bases
ATGGGTATAAAAATTATGGCTGTATTTGGGACAAGACCTGAAGCAATTAAAATGGCTCCACTTATTAAGGCTCTGGAGAA
AGAAAAAGAGTTTGACACACAAGTAGCTGTTACAGCCCAGCACCGTGAAATGCTTGACCAGGTGCTGAGGCTTTTTAATA
TTGTGCCTCAATACGACCTTAACATAATGAGAGAGAGGCAGACTTTATCTGACATTACTACTGCTGCTATAGACGGCCTT
GATAGAGTGTTTCTTAAAGAAAAACCGAACCTTGTTTTGGTTCACGGGGATACTACTACTACATTTGCGGCGGCACTGGT
GGCTTTTTATCACAAAATAAAAGTGGGGCACGTGGAAGCAGGTTTGAGGTCTTTTAACAAATGGTTCCCTTATCCTGAGG
AGATAAACAGAAAATTGACAGGGGTGCTGGCAGACCTGCATTTTGCTCCTACAAAAAGGGCTAAATTAAATCTTTTAAAT
GAAGGAGTAGAGGAAGAAAGCATTTTTGTTACAGGAAATACAGTAATTGACGCTATGTCCTATACAGTAAAGAAAGATTA
CACTTTCAGGGAGGAAAGATTAAATAGGATTGATTATAAAAACAAAAAGGTCATAGTAGTCACAGCCCATAGGAGGGAGA
ACTGGGGAGCACCTCTAGAGAACATATGCAACGCTATTAAAGATATAGCAAAAAGCTACAAAGAAGAAGTGTACTTTATA
TACCCTGTTCATATGAATCCAGTGGTGAAAAATACGGCCCATAAAATTTTAGGAGGGTTTGACAATGTGCTTCTTTTAGA
CCCTCTTGAGACGGATGAGATGCATAACCTTTTAGCCAGATGCTATATGGTTATGACAGATTCAGGAGGGCTTCAGGAGG
AAGTGCCATCACTGGGCAAACCAGTTCTGGTTTTGAGGGATGTGACAGAAAGGCCTGAGGCAAAAGAGGCAGGAACTGTG
AAGTTGGTTGGGACGGATTATGAAAGGATTTTTAAAGAGGCAAAGCTTCTCATAGAGGACGAAAATGAGTATAAAAAAAT
GGCCAATGCGGTAAATCCCTATGGCGATGGGAAAGCATCGGTGAGAATAGTTGGAGCGATAAAATACTTTTTTGGGCTAT
CAAAAGAAAAGCCGGAAGAATACGAAGGAGGGGGATAA

Upstream 100 bases:

>100_bases
CCCTCCTCTTTATACTCTGGGGAGCAAATAAAATAGAATTGCTAAGAAGCAATAAAAAAGGGACGCAAACCCGCTGATTT
TATTAAGGAGTGCAAGACTG

Downstream 100 bases:

>100_bases
AGCCCCCTCCTTAAATTGTTATTTGCTTGCTTCTTGCTTCGTTTGGCTTTTTGCGATTAAGTACCAGATATATCCAATAA
CTATTGCTCCGATGAAGCCG

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MGIKIMAVFGTRPEAIKMAPLIKALEKEKEFDTQVAVTAQHREMLDQVLRLFNIVPQYDLNIMRERQTLSDITTAAIDGL
DRVFLKEKPNLVLVHGDTTTTFAAALVAFYHKIKVGHVEAGLRSFNKWFPYPEEINRKLTGVLADLHFAPTKRAKLNLLN
EGVEEESIFVTGNTVIDAMSYTVKKDYTFREERLNRIDYKNKKVIVVTAHRRENWGAPLENICNAIKDIAKSYKEEVYFI
YPVHMNPVVKNTAHKILGGFDNVLLLDPLETDEMHNLLARCYMVMTDSGGLQEEVPSLGKPVLVLRDVTERPEAKEAGTV
KLVGTDYERIFKEAKLLIEDENEYKKMANAVNPYGDGKASVRIVGAIKYFFGLSKEKPEEYEGGG

Sequences:

>Translated_385_residues
MGIKIMAVFGTRPEAIKMAPLIKALEKEKEFDTQVAVTAQHREMLDQVLRLFNIVPQYDLNIMRERQTLSDITTAAIDGL
DRVFLKEKPNLVLVHGDTTTTFAAALVAFYHKIKVGHVEAGLRSFNKWFPYPEEINRKLTGVLADLHFAPTKRAKLNLLN
EGVEEESIFVTGNTVIDAMSYTVKKDYTFREERLNRIDYKNKKVIVVTAHRRENWGAPLENICNAIKDIAKSYKEEVYFI
YPVHMNPVVKNTAHKILGGFDNVLLLDPLETDEMHNLLARCYMVMTDSGGLQEEVPSLGKPVLVLRDVTERPEAKEAGTV
KLVGTDYERIFKEAKLLIEDENEYKKMANAVNPYGDGKASVRIVGAIKYFFGLSKEKPEEYEGGG
>Mature_384_residues
GIKIMAVFGTRPEAIKMAPLIKALEKEKEFDTQVAVTAQHREMLDQVLRLFNIVPQYDLNIMRERQTLSDITTAAIDGLD
RVFLKEKPNLVLVHGDTTTTFAAALVAFYHKIKVGHVEAGLRSFNKWFPYPEEINRKLTGVLADLHFAPTKRAKLNLLNE
GVEEESIFVTGNTVIDAMSYTVKKDYTFREERLNRIDYKNKKVIVVTAHRRENWGAPLENICNAIKDIAKSYKEEVYFIY
PVHMNPVVKNTAHKILGGFDNVLLLDPLETDEMHNLLARCYMVMTDSGGLQEEVPSLGKPVLVLRDVTERPEAKEAGTVK
LVGTDYERIFKEAKLLIEDENEYKKMANAVNPYGDGKASVRIVGAIKYFFGLSKEKPEEYEGGG

Specific function: Catalyzes The Reversible Epimerization At C-2 Of UDP-N- Acetylglucosamine (UDP-Glcnac) And Thereby Provides Bacteria With UDP-N-Acetylmannosamine (UDP-Mannac), The Activated Donor Of Mannac Residues. Also Involved In Bacteriophage N4 Adsorption. [C]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=374, Percent_Identity=53.7433155080214, Blast_Score=387, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 43615; Mature: 43484

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIKIMAVFGTRPEAIKMAPLIKALEKEKEFDTQVAVTAQHREMLDQVLRLFNIVPQYDL
CCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCCH
NIMRERQTLSDITTAAIDGLDRVFLKEKPNLVLVHGDTTTTFAAALVAFYHKIKVGHVEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
GLRSFNKWFPYPEEINRKLTGVLADLHFAPTKRAKLNLLNEGVEEESIFVTGNTVIDAMS
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHH
YTVKKDYTFREERLNRIDYKNKKVIVVTAHRRENWGAPLENICNAIKDIAKSYKEEVYFI
HHHHCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEE
YPVHMNPVVKNTAHKILGGFDNVLLLDPLETDEMHNLLARCYMVMTDSGGLQEEVPSLGK
EEECCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHEEEECCCCCHHHHHCCCC
PVLVLRDVTERPEAKEAGTVKLVGTDYERIFKEAKLLIEDENEYKKMANAVNPYGDGKAS
CEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHEEEECCHHHHHHHHHCCCCCCCCCE
VRIVGAIKYFFGLSKEKPEEYEGGG
EEEEEHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
GIKIMAVFGTRPEAIKMAPLIKALEKEKEFDTQVAVTAQHREMLDQVLRLFNIVPQYDL
CEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCCH
NIMRERQTLSDITTAAIDGLDRVFLKEKPNLVLVHGDTTTTFAAALVAFYHKIKVGHVEA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
GLRSFNKWFPYPEEINRKLTGVLADLHFAPTKRAKLNLLNEGVEEESIFVTGNTVIDAMS
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHHH
YTVKKDYTFREERLNRIDYKNKKVIVVTAHRRENWGAPLENICNAIKDIAKSYKEEVYFI
HHHHCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCEEEE
YPVHMNPVVKNTAHKILGGFDNVLLLDPLETDEMHNLLARCYMVMTDSGGLQEEVPSLGK
EEECCCCHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHEEEECCCCCHHHHHCCCC
PVLVLRDVTERPEAKEAGTVKLVGTDYERIFKEAKLLIEDENEYKKMANAVNPYGDGKAS
CEEEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHEEEECCHHHHHHHHHCCCCCCCCCE
VRIVGAIKYFFGLSKEKPEEYEGGG
EEEEEHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286; 7867955 [H]