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The map label for this gene is NagC [H]

Identifier: 20806619

GI number: 20806619

Start: 94148

End: 95095

Strand: Direct

Name: NagC [H]

Synonym: TTE0090

Alternate gene names: 20806619

Gene position: 94148-95095 (Clockwise)

Preceding gene: 20806618

Following gene: 20806620

Centisome position: 3.5

GC content: 42.3

Gene sequence:

>948_bases
TTGAAGAAGTTTCTCTGTGGAGTTGATTTGGGAGGCACAAAGATAAGCACAGGCATTGTTGATGAAAATGGCAACATAAT
AAAGAGCATAAAAATTCCAACAATGGCTGAAAAAGGACCAGACGTGGTGATTGAAAGGATTGAAGAGAGCATATATCAGG
TTTTAAAAGATACAGGACTTGAAATGAGCAATTTAAAAGGTATCGGGATAGGGTCTCCTGGGCCTTTGAATGCCAAAAAG
GGGATTGTGATAAGCCCTCCAAATTTGCCTCACTGGAGTAACGTCCCTATAGTGGAAATTTTGTCGAAAAGGCTTGGCAT
AGAGGTTAGACTGGAAAATGACGCAAATGCAGCTGCAATAGGAGAACACCTTTTTGGATCAGGTAGAGGAGTAGATAATT
TTGTGTACATAACAGTCAGCACTGGAATTGGCGGAGGAGTCATAATTGAAGGGAAATTATATAGTGGAGAGAATTCGAAT
GCTGCAGAGATTGGACATCACACCATAAACTTTGATGGGCCGAGGTGCAACTGCGGAAATTACGGATGCTTTGAAGCTTA
CGCTTCTGGAACGGCGATTGCCAGATTTGCAAGGGAAGGGATTGAAAAAGGGATAAAGACGAAAATAAAGGAACTGGCGG
GAGAAGGAGAAGTAAAAGCAGAGCACGTGTTCGAAGCTGCAAAACTGGGAGATGAATTCGCAAAAGAATTGGTAGAAAAG
GAGGCTTTTTACTTGGGAGTGGGAATTGCCAACATAATGGCTTTTTACAATCCCAGAAAGATCGCCATAGGGGGAGGAGT
TTCTGCTCAGTGGGATATGTTGTATGAGAAAATGATGGAAACTGTAAGAAAAAAGGCATTAAAACCCAATGCAGAAGTAT
GTGAAGTGGTAAAGGCTCAGCTGGGAGAAAATATAGGAGTTTTGGGGGCTGCTGCATTGCTCTTGTGA

Upstream 100 bases:

>100_bases
AACGTAATGAAGGGCCCTTTACGGGCCTTTTTTAGTTTATTGAAATTTTCAATAATGGTATAATTAGTTTAAAAGGTTTT
TAATGAGGGAGGTAGTAAAG

Downstream 100 bases:

>100_bases
GGGGATGAATATGCAAAGATGCCCTTGGTGCCTCGTGGATCCGATTTATATAAAGTATCACGATGAGGAATGGGGAGTGC
CTGTCCACGACGATAGGAAG

Product: transcriptional regulator

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKKFLCGVDLGGTKISTGIVDENGNIIKSIKIPTMAEKGPDVVIERIEESIYQVLKDTGLEMSNLKGIGIGSPGPLNAKK
GIVISPPNLPHWSNVPIVEILSKRLGIEVRLENDANAAAIGEHLFGSGRGVDNFVYITVSTGIGGGVIIEGKLYSGENSN
AAEIGHHTINFDGPRCNCGNYGCFEAYASGTAIARFAREGIEKGIKTKIKELAGEGEVKAEHVFEAAKLGDEFAKELVEK
EAFYLGVGIANIMAFYNPRKIAIGGGVSAQWDMLYEKMMETVRKKALKPNAEVCEVVKAQLGENIGVLGAAALLL

Sequences:

>Translated_315_residues
MKKFLCGVDLGGTKISTGIVDENGNIIKSIKIPTMAEKGPDVVIERIEESIYQVLKDTGLEMSNLKGIGIGSPGPLNAKK
GIVISPPNLPHWSNVPIVEILSKRLGIEVRLENDANAAAIGEHLFGSGRGVDNFVYITVSTGIGGGVIIEGKLYSGENSN
AAEIGHHTINFDGPRCNCGNYGCFEAYASGTAIARFAREGIEKGIKTKIKELAGEGEVKAEHVFEAAKLGDEFAKELVEK
EAFYLGVGIANIMAFYNPRKIAIGGGVSAQWDMLYEKMMETVRKKALKPNAEVCEVVKAQLGENIGVLGAAALLL
>Mature_315_residues
MKKFLCGVDLGGTKISTGIVDENGNIIKSIKIPTMAEKGPDVVIERIEESIYQVLKDTGLEMSNLKGIGIGSPGPLNAKK
GIVISPPNLPHWSNVPIVEILSKRLGIEVRLENDANAAAIGEHLFGSGRGVDNFVYITVSTGIGGGVIIEGKLYSGENSN
AAEIGHHTINFDGPRCNCGNYGCFEAYASGTAIARFAREGIEKGIKTKIKELAGEGEVKAEHVFEAAKLGDEFAKELVEK
EAFYLGVGIANIMAFYNPRKIAIGGGVSAQWDMLYEKMMETVRKKALKPNAEVCEVVKAQLGENIGVLGAAALLL

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=287, Percent_Identity=34.4947735191638, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI298566325, Length=287, Percent_Identity=34.4947735191638, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI4885285, Length=287, Percent_Identity=34.4947735191638, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI190014632, Length=287, Percent_Identity=34.4947735191638, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI298566312, Length=139, Percent_Identity=32.3741007194245, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1787878, Length=272, Percent_Identity=29.0441176470588, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786891, Length=308, Percent_Identity=25.974025974026, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787363, Length=319, Percent_Identity=28.5266457680251, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87081733, Length=318, Percent_Identity=28.9308176100629, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082230, Length=260, Percent_Identity=31.5384615384615, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082127, Length=231, Percent_Identity=25.1082251082251, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1790522, Length=314, Percent_Identity=24.5222929936306, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33576; Mature: 33576

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFLCGVDLGGTKISTGIVDENGNIIKSIKIPTMAEKGPDVVIERIEESIYQVLKDTGL
CCCEEEECCCCCCEEEECEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCC
EMSNLKGIGIGSPGPLNAKKGIVISPPNLPHWSNVPIVEILSKRLGIEVRLENDANAAAI
CHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCHHHH
GEHLFGSGRGVDNFVYITVSTGIGGGVIIEGKLYSGENSNAAEIGHHTINFDGPRCNCGN
HHHHHCCCCCCCEEEEEEEECCCCCCEEEEEEEECCCCCCHHHHCCEEEECCCCCCCCCC
YGCFEAYASGTAIARFAREGIEKGIKTKIKELAGEGEVKAEHVFEAAKLGDEFAKELVEK
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EAFYLGVGIANIMAFYNPRKIAIGGGVSAQWDMLYEKMMETVRKKALKPNAEVCEVVKAQ
HHHEEEHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LGENIGVLGAAALLL
HCCCCCHHHHHHHHC
>Mature Secondary Structure
MKKFLCGVDLGGTKISTGIVDENGNIIKSIKIPTMAEKGPDVVIERIEESIYQVLKDTGL
CCCEEEECCCCCCEEEECEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCC
EMSNLKGIGIGSPGPLNAKKGIVISPPNLPHWSNVPIVEILSKRLGIEVRLENDANAAAI
CHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCHHHH
GEHLFGSGRGVDNFVYITVSTGIGGGVIIEGKLYSGENSNAAEIGHHTINFDGPRCNCGN
HHHHHCCCCCCCEEEEEEEECCCCCCEEEEEEEECCCCCCHHHHCCEEEECCCCCCCCCC
YGCFEAYASGTAIARFAREGIEKGIKTKIKELAGEGEVKAEHVFEAAKLGDEFAKELVEK
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
EAFYLGVGIANIMAFYNPRKIAIGGGVSAQWDMLYEKMMETVRKKALKPNAEVCEVVKAQ
HHHEEEHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LGENIGVLGAAALLL
HCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]