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The map label for this gene is tadA [H]

Identifier: 20806575

GI number: 20806575

Start: 45574

End: 46020

Strand: Direct

Name: tadA [H]

Synonym: TTE0037

Alternate gene names: 20806575

Gene position: 45574-46020 (Clockwise)

Preceding gene: 20806574

Following gene: 20806576

Centisome position: 1.69

GC content: 40.94

Gene sequence:

>447_bases
ATGGCAAATAAATTTATGGAAGAAGCCTTGAAAGAAGCGAAGAAAAGCTACGAATTAGGCGAAGTTCCTGTTGGAGCTGT
CATAGTGAAAGATGGGGAAATAATAGCGAGAGGACATAACCAAAAAGAATCGTCAAAGGATGCCACAGCTCATGCAGAAA
TAATTGCCATAAGAGAAGCCTGCAGAAGGTTGGGGAGTTGGAGGCTTGAAGATTGTAGCTTGTATGTGACGCTGGAACCC
TGTCCCATGTGTGCAGGTGCTATTGTTGAAGCTCGAATAAAAAGAGTCTATATAGGGACAGAGAGCCCAAAAGAAGGGGC
AGCTGGTTCGGTTATAAATATCTTGAATAACAAAGAGTTAGGGACTAGCACTGAAGTTTACTTTGGGATAATGGAAGAAG
AAGCGAAGGAACTTCTCAAAAAGTTTTTTGAAAATTTAAGAGAGTAA

Upstream 100 bases:

>100_bases
ATGAATATTTTGGAATTTAATTCCATAAATTAATGATTGTGTTCACTTGACATGAGAGAGATTCTCTGATAAAATACATT
CATGCAGAGAGTGAAAAGCA

Downstream 100 bases:

>100_bases
GTGCGGAGAGATGGCTGAGTGGTCGAAAGCGCTCGCCTCGAAAGCGAGTGGGCGAATTTTTCGCCTCGAGGGTTCAAATC
CCTCTCTCTCCGCCACTTAG

Product: cytosine/adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MANKFMEEALKEAKKSYELGEVPVGAVIVKDGEIIARGHNQKESSKDATAHAEIIAIREACRRLGSWRLEDCSLYVTLEP
CPMCAGAIVEARIKRVYIGTESPKEGAAGSVINILNNKELGTSTEVYFGIMEEEAKELLKKFFENLRE

Sequences:

>Translated_148_residues
MANKFMEEALKEAKKSYELGEVPVGAVIVKDGEIIARGHNQKESSKDATAHAEIIAIREACRRLGSWRLEDCSLYVTLEP
CPMCAGAIVEARIKRVYIGTESPKEGAAGSVINILNNKELGTSTEVYFGIMEEEAKELLKKFFENLRE
>Mature_147_residues
ANKFMEEALKEAKKSYELGEVPVGAVIVKDGEIIARGHNQKESSKDATAHAEIIAIREACRRLGSWRLEDCSLYVTLEPC
PMCAGAIVEARIKRVYIGTESPKEGAAGSVINILNNKELGTSTEVYFGIMEEEAKELLKKFFENLRE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=149, Percent_Identity=39.5973154362416, Blast_Score=99, Evalue=2e-21,
Organism=Escherichia coli, GI145693172, Length=144, Percent_Identity=43.0555555555556, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786616, Length=151, Percent_Identity=33.112582781457, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554608, Length=99, Percent_Identity=48.4848484848485, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17541138, Length=145, Percent_Identity=34.4827586206897, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555996, Length=99, Percent_Identity=42.4242424242424, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325319, Length=105, Percent_Identity=40.9523809523809, Blast_Score=77, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6322425, Length=155, Percent_Identity=32.258064516129, Blast_Score=72, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=37.6712328767123, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16422; Mature: 16291

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKFMEEALKEAKKSYELGEVPVGAVIVKDGEIIARGHNQKESSKDATAHAEIIAIREA
CCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHH
CRRLGSWRLEDCSLYVTLEPCPMCAGAIVEARIKRVYIGTESPKEGAAGSVINILNNKEL
HHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHCCCCC
GTSTEVYFGIMEEEAKELLKKFFENLRE
CCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANKFMEEALKEAKKSYELGEVPVGAVIVKDGEIIARGHNQKESSKDATAHAEIIAIREA
CHHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCHHHHHHHHHHHHH
CRRLGSWRLEDCSLYVTLEPCPMCAGAIVEARIKRVYIGTESPKEGAAGSVINILNNKEL
HHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHEEEECCCCCCCCCCCHHHHHHCCCCC
GTSTEVYFGIMEEEAKELLKKFFENLRE
CCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]