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The map label for this gene is ArsA

Identifier: 20095116

GI number: 20095116

Start: 1681881

End: 1682882

Strand: Direct

Name: ArsA

Synonym: MK1680

Alternate gene names: NA

Gene position: 1681881-1682882 (Clockwise)

Preceding gene: 20095113

Following gene: 20095117

Centisome position: 99.23

GC content: 55.59

Gene sequence:

>1002_bases
ATGGGCATCTCGGAGAAACTCGGGCTATCGAAGGGTCAGCGGTACGTCTTCTTCGGCGGTAAAGGAGGAGTCGGAAAAAC
AACCTGTGCCGCGGCCACTGCCGTGTGGCTATCCGAGGAGGAAGGGAAGGAAGTACTAGTGGTCTCAACGGATCCGGCGC
ACTCGCTCTCGGACATTTTCGATCAGAACATCGGCTCGGAGCCTACCCCGATCGAAGGTGTAGAGGGACTCAAGGCGATC
GAAATCGATCCGGAGAAAGCTGCGGAAGAGTACGTCGAGGTGATGAAGCGAGTGTACGAGATGTCGAAGGATAAGGGAAT
GGAAGACCTGTTCGGAGGCGAAGACCTGCTCAAAGAGCAAGAGGAACTGCTGAAATCATCGCCGGGTATCGACGAGGCGG
CGGCGTTCCAGAAGTTCATGGAACTGATGAAGGATGACTCGTACGACGTGATCGTGTTCGATACCGCCCCCACGGGCCAC
ACCCTGAGGTTCCTCTCAGTACCCGAGACGCTGGAACGCCAGGTGAAGACGATGATCAAAGTCAGACGGACCCTGCGTCA
AGTCAGCAAGATGCTGAAGACGCTGATACCGTTCGCCGACTCGGATGAGGACGAAGAAGACGAGATCCTGGAGAATCTGG
AGAAGATGAAGAAGGAGATCGAGGAAATACGAGAGACCTTAAGCGACGCATCGCTGACGGCCTTCCGGCTGGTGATGACT
CCGGAAGAGATGGCAATTTACGAGGCACGCCGCGCCCTACGTACGCTGAACCACTACGAGATTCCCGTCGATATGGTCAT
CGTGAACAAGGTAATGCCGAAACGAGCGGACGAGTGCGAGTTCTGTCGCACTCGTCGTAAGATGGAAGAGAAGCGTCTCA
AGCTAGTGGAGAAGTACTTCGGAGACAAGGAGATACACCAGATTCCGATGTTTGCGGAGGAAGTGCGCGGTCTGGGGAAG
ATCCGTCAAGTCGCCGAGATACTGTACGGTGAACCGGCCTGA

Upstream 100 bases:

>100_bases
GTTCCCGAGCCAGCTCCCGCGCGAAACACGTTTTACCTGACCCGGGCGGGCCGGTGAGTATCAGCAGTCGCAACCTTTGT
AACCCCCAGGGGGTCTGGTG

Downstream 100 bases:

>100_bases
GGGTCAGCGTCTTGGTCAGGAAGCCGAAAAAGTTCCCGAAGCGCCGATACGAGCTCCACGCCCACACTTACCTGACCGAC
GGTGAGCTGCTACCGGCTGA

Product: arsenite transporting ATPase

Products: NA

Alternate protein names: Arsenical resistance ATPase; Arsenite-translocating ATPase; Arsenite-transporting ATPase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MGISEKLGLSKGQRYVFFGGKGGVGKTTCAAATAVWLSEEEGKEVLVVSTDPAHSLSDIFDQNIGSEPTPIEGVEGLKAI
EIDPEKAAEEYVEVMKRVYEMSKDKGMEDLFGGEDLLKEQEELLKSSPGIDEAAAFQKFMELMKDDSYDVIVFDTAPTGH
TLRFLSVPETLERQVKTMIKVRRTLRQVSKMLKTLIPFADSDEDEEDEILENLEKMKKEIEEIRETLSDASLTAFRLVMT
PEEMAIYEARRALRTLNHYEIPVDMVIVNKVMPKRADECEFCRTRRKMEEKRLKLVEKYFGDKEIHQIPMFAEEVRGLGK
IRQVAEILYGEPA

Sequences:

>Translated_333_residues
MGISEKLGLSKGQRYVFFGGKGGVGKTTCAAATAVWLSEEEGKEVLVVSTDPAHSLSDIFDQNIGSEPTPIEGVEGLKAI
EIDPEKAAEEYVEVMKRVYEMSKDKGMEDLFGGEDLLKEQEELLKSSPGIDEAAAFQKFMELMKDDSYDVIVFDTAPTGH
TLRFLSVPETLERQVKTMIKVRRTLRQVSKMLKTLIPFADSDEDEEDEILENLEKMKKEIEEIRETLSDASLTAFRLVMT
PEEMAIYEARRALRTLNHYEIPVDMVIVNKVMPKRADECEFCRTRRKMEEKRLKLVEKYFGDKEIHQIPMFAEEVRGLGK
IRQVAEILYGEPA
>Mature_332_residues
GISEKLGLSKGQRYVFFGGKGGVGKTTCAAATAVWLSEEEGKEVLVVSTDPAHSLSDIFDQNIGSEPTPIEGVEGLKAIE
IDPEKAAEEYVEVMKRVYEMSKDKGMEDLFGGEDLLKEQEELLKSSPGIDEAAAFQKFMELMKDDSYDVIVFDTAPTGHT
LRFLSVPETLERQVKTMIKVRRTLRQVSKMLKTLIPFADSDEDEEDEILENLEKMKKEIEEIRETLSDASLTAFRLVMTP
EEMAIYEARRALRTLNHYEIPVDMVIVNKVMPKRADECEFCRTRRKMEEKRLKLVEKYFGDKEIHQIPMFAEEVRGLGKI
RQVAEILYGEPA

Specific function: Anion-transporting ATPase. Catalyzes the extrusion of arsenite [H]

COG id: COG0003

COG function: function code P; Oxyanion-translocating ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arsA ATPase family [H]

Homologues:

Organism=Homo sapiens, GI50428938, Length=325, Percent_Identity=33.8461538461538, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI17557003, Length=325, Percent_Identity=32.6153846153846, Blast_Score=143, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320103, Length=314, Percent_Identity=30.8917197452229, Blast_Score=168, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24586297, Length=331, Percent_Identity=33.2326283987915, Blast_Score=165, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003348 [H]

Pfam domain/function: NA

EC number: =3.6.3.16 [H]

Molecular weight: Translated: 37846; Mature: 37715

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGISEKLGLSKGQRYVFFGGKGGVGKTTCAAATAVWLSEEEGKEVLVVSTDPAHSLSDIF
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
DQNIGSEPTPIEGVEGLKAIEIDPEKAAEEYVEVMKRVYEMSKDKGMEDLFGGEDLLKEQ
HHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHH
EELLKSSPGIDEAAAFQKFMELMKDDSYDVIVFDTAPTGHTLRFLSVPETLERQVKTMIK
HHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHH
VRRTLRQVSKMLKTLIPFADSDEDEEDEILENLEKMKKEIEEIRETLSDASLTAFRLVMT
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEC
PEEMAIYEARRALRTLNHYEIPVDMVIVNKVMPKRADECEFCRTRRKMEEKRLKLVEKYF
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GDKEIHQIPMFAEEVRGLGKIRQVAEILYGEPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GISEKLGLSKGQRYVFFGGKGGVGKTTCAAATAVWLSEEEGKEVLVVSTDPAHSLSDIF
CCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
DQNIGSEPTPIEGVEGLKAIEIDPEKAAEEYVEVMKRVYEMSKDKGMEDLFGGEDLLKEQ
HHCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHH
EELLKSSPGIDEAAAFQKFMELMKDDSYDVIVFDTAPTGHTLRFLSVPETLERQVKTMIK
HHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCHHHHHHHHHHHH
VRRTLRQVSKMLKTLIPFADSDEDEEDEILENLEKMKKEIEEIRETLSDASLTAFRLVMT
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEEC
PEEMAIYEARRALRTLNHYEIPVDMVIVNKVMPKRADECEFCRTRRKMEEKRLKLVEKYF
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GDKEIHQIPMFAEEVRGLGKIRQVAEILYGEPA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]