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The map label for this gene is yjfR [C]

Identifier: 20094978

GI number: 20094978

Start: 1560542

End: 1561234

Strand: Direct

Name: yjfR [C]

Synonym: MK1542

Alternate gene names: 20094978

Gene position: 1560542-1561234 (Clockwise)

Preceding gene: 20094970

Following gene: 20094981

Centisome position: 92.07

GC content: 61.9

Gene sequence:

>693_bases
ATGAGGATAACGTGGCTGGGTCATGCGGCGTTCGAAGTGGAAATCGACGGAGTCAACGTGCTCATCGACCCGTTCTTAAG
TGGGAATCCGAAGGCGGCCAAGTCACCGGACGAGGTGGATCCGGACCTTGTCCTCGTGACTCACGGTCACGGCGATCACC
TGGGTGACGCCGTCGAGATCTGCAAGCGCACTGGAGCTACGCTGGTCGGGATCTACGAGATCGCCGTGTACGCCCAGGGA
CAGGGCGTCGAGAACGTGGAGGAGATGAACATCGGCGGCACCATCGAGGTGGAGGGACTGGAGATCACCCAGGTGCCGGC
GTGGCACTCCTCGGAGATCGTCGAAGACGGGGAGATAGTCGCCGGCGGCACCCCGGTGGGTTACGTGGTATCAGGTGAGG
AAGGGTCGGTTTACCACGCGGGCGACACCGGCCTGTCCATGGACATGAAGCTCATCGGTGAGCTCTACGAGCCGGAGGTG
GCACTGTTACCGATAGGCAGCAGGTTCACCATGGGACCCAAGGAGGCCGCTAAGGCCGTGGAGCTGATCGAGCCGGAGGT
GGCGATACCGATGCACTACGGGACCTTCCCGCCGATCGAGCAGGATCCCGAGGAATTCAAACGGGAGGTGGAGGAACTCG
GACTGGACGTGGAAGTCGTGATCCTGGAGCCGGGAGAGTCGTACGAAAGGTAG

Upstream 100 bases:

>100_bases
GTTCCAAAGTCCATGACGATACGCGGCGGGAGCGAGCTCGCCCACTTTCGCTGAGTTTTTAGGGAGGTGTTTGAGACGAC
TCGTAGCGGGGGGTAAGCCC

Downstream 100 bases:

>100_bases
GGATGACGAGCACCTTTCCAACCGAGTGGTGAGGACCGCCGTCGGGCCCGACCTCCCTCACTCTACTTTCACGACTTCAC
GGTTGATCAGCTCGACGAAC

Product: metal-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MRITWLGHAAFEVEIDGVNVLIDPFLSGNPKAAKSPDEVDPDLVLVTHGHGDHLGDAVEICKRTGATLVGIYEIAVYAQG
QGVENVEEMNIGGTIEVEGLEITQVPAWHSSEIVEDGEIVAGGTPVGYVVSGEEGSVYHAGDTGLSMDMKLIGELYEPEV
ALLPIGSRFTMGPKEAAKAVELIEPEVAIPMHYGTFPPIEQDPEEFKREVEELGLDVEVVILEPGESYER

Sequences:

>Translated_230_residues
MRITWLGHAAFEVEIDGVNVLIDPFLSGNPKAAKSPDEVDPDLVLVTHGHGDHLGDAVEICKRTGATLVGIYEIAVYAQG
QGVENVEEMNIGGTIEVEGLEITQVPAWHSSEIVEDGEIVAGGTPVGYVVSGEEGSVYHAGDTGLSMDMKLIGELYEPEV
ALLPIGSRFTMGPKEAAKAVELIEPEVAIPMHYGTFPPIEQDPEEFKREVEELGLDVEVVILEPGESYER
>Mature_230_residues
MRITWLGHAAFEVEIDGVNVLIDPFLSGNPKAAKSPDEVDPDLVLVTHGHGDHLGDAVEICKRTGATLVGIYEIAVYAQG
QGVENVEEMNIGGTIEVEGLEITQVPAWHSSEIVEDGEIVAGGTPVGYVVSGEEGSVYHAGDTGLSMDMKLIGELYEPEV
ALLPIGSRFTMGPKEAAKAVELIEPEVAIPMHYGTFPPIEQDPEEFKREVEELGLDVEVVILEPGESYER

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0173 family

Homologues:

Organism=Homo sapiens, GI170932483, Length=263, Percent_Identity=28.1368821292776, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI170932481, Length=263, Percent_Identity=28.1368821292776, Blast_Score=85, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1542_METKA (Q8TV58)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614825.1
- ProteinModelPortal:   Q8TV58
- GeneID:   1478137
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK1542
- NMPDR:   fig|190192.1.peg.1538
- HOGENOM:   HBG741314
- OMA:   FPIIDQT
- ProtClustDB:   PRK00685
- BioCyc:   MKAN190192:MK1542-MONOMER
- HAMAP:   MF_00457
- InterPro:   IPR001279
- InterPro:   IPR022877
- SMART:   SM00849

Pfam domain/function: PF00753 Lactamase_B

EC number: NA

Molecular weight: Translated: 24762; Mature: 24762

Theoretical pI: Translated: 3.92; Mature: 3.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITWLGHAAFEVEIDGVNVLIDPFLSGNPKAAKSPDEVDPDLVLVTHGHGDHLGDAVEI
CEEEEEECEEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
CKRTGATLVGIYEIAVYAQGQGVENVEEMNIGGTIEVEGLEITQVPAWHSSEIVEDGEIV
HHHCCCEEEEEEEEEEEECCCCCCCHHHCCCCCEEEECCEEEEECCCCCCCCCCCCCCEE
AGGTPVGYVVSGEEGSVYHAGDTGLSMDMKLIGELYEPEVALLPIGSRFTMGPKEAAKAV
ECCCCEEEEEECCCCCEEECCCCCCEECHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHH
ELIEPEVAIPMHYGTFPPIEQDPEEFKREVEELGLDVEVVILEPGESYER
HHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MRITWLGHAAFEVEIDGVNVLIDPFLSGNPKAAKSPDEVDPDLVLVTHGHGDHLGDAVEI
CEEEEEECEEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHH
CKRTGATLVGIYEIAVYAQGQGVENVEEMNIGGTIEVEGLEITQVPAWHSSEIVEDGEIV
HHHCCCEEEEEEEEEEEECCCCCCCHHHCCCCCEEEECCEEEEECCCCCCCCCCCCCCEE
AGGTPVGYVVSGEEGSVYHAGDTGLSMDMKLIGELYEPEVALLPIGSRFTMGPKEAAKAV
ECCCCEEEEEECCCCCEEECCCCCCEECHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHH
ELIEPEVAIPMHYGTFPPIEQDPEEFKREVEELGLDVEVVILEPGESYER
HHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014