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The map label for this gene is rsmB [H]

Identifier: 20094975

GI number: 20094975

Start: 1556613

End: 1557965

Strand: Reverse

Name: rsmB [H]

Synonym: MK1539

Alternate gene names: 20094975

Gene position: 1557965-1556613 (Counterclockwise)

Preceding gene: 20094976

Following gene: 20094974

Centisome position: 91.92

GC content: 61.27

Gene sequence:

>1353_bases
GTGACGTCTCGGGACGCTAAGACCTACGAGGAAGCCGTGGAGATAGTGCTCCGTACGCTGGTGAAAGCGGAGAGGATCAA
ACCCACGCAGTACGCCAGACGTCTGGTGATGAAGGAGATGAACCCCTCTCGAGAAGCCAGGTCCGTGTCCGCCGGGCTGC
TGTACAGTGTGCTACAGAAACGCGGACTCTTGGACGAGGTAATAGAGGACGTCCTGGAGATCACGGATGACGTGACCGAG
CTCGACACGTGGGTCAGGAACGCGGCACGGATCGCCGTGAACGAGGTCGTGTTCGAAGACGGCGACCCCGACGAGGTAGC
CGACGTGCTACACGGGCTGGTCCGGAGGCTAGCCAATCCCGGGGCGGCGGCGATCGTGAAGGCGTTCACACTGGATTTGA
AGGACTACGAACCTCCCGAGCCGGAGGACGAACTCGACAGGTTGAAGTGGGAGTACTACCATCCGCGGTGGCTGATCGAG
CGATGGATGGAGATGTTCGGCGACCCTGACGAGGTGGTCGCCTTACTGGAAGCCAACAACCGAAGGCCGCCGCTGACCAT
CCGCGTGAACACCCTCAAGGTGGACCCTGAAGAGCTGGCGGAGCGGTTACAGAGGAAGTACCGGGTCACGGTCGAGCCGG
GACGCTTCTTGGACGAAATACTGAAGATTCCCGAGGGACTTCCCATCGGAGAGATGCCGGAGTGGGAAGAGGGCCTCTTC
GTGATCCAGGACGAGGCCGCGGCGCTCGCATCCGCAGTTCTCAACCCGAAACCCGGGGAGGTGGTCGTCGACCTTTGTGC
GGCTCCGGGCGGTAAGACCACCCACATGGCGCAGCTGATGGGAGGAGAGGGCAAGATTGTGGCGATCGACGTGGACGAGG
TTCGGATGGAACGTCTCCGGGAGATCGCGGAACGTATGGGCGTCCTCGACTGCATTGAAACACACCTGATGGACGGACGC
GAAGCGCCCGAGAAGCTGGGTCGTGAGTTTGCCGACGCCGTGTTAGTCGATCCACCGTGCTCCGCCGACGGTACGATTCC
GAAGAATCCCGAGCGCCGGTGGAGGATCACCCCGGATGAACTGGAACGACTGCCCAAGTTCCAGTACGAGCTCCTGAAAG
CGGGTGCCGAAATGGTCAAACCGGGAGGTCGTCTGCTGTACTCCACGTGCTCGATGTTCCCCGAGGAGGATGAGGAGGTA
GTCCGAAGGTTCTTGGATGAGCACCCCGAGTTCGAGCTGCTGGAAGTCAAGGTCGGTGACCAGGGGTTCGACATGCCCGA
GGCGTGCCGACTGTTCCCGCACCGACATGAGACCTGTGGATTCTTCATAGCACTCATGGGACGGACCGGCTGA

Upstream 100 bases:

>100_bases
GACTTCGGAGAACTCGTTCGCACGCTGAAGGAGTACGTTCGAACTCGGGACGATACGTTCGAAGTACATCAAGGGACGTC
GGTGATGGGGCGGATGCGCG

Downstream 100 bases:

>100_bases
TGGGGGTTACGCTGATGAAGGTGGAGCGACCCAAGGGCACCCGCGACTTCACCCCGGAGGAGATGAGGGCACGCAGATGG
CTGGAGCGGTACCTGTTGGA

Product: tRNA/rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTSRDAKTYEEAVEIVLRTLVKAERIKPTQYARRLVMKEMNPSREARSVSAGLLYSVLQKRGLLDEVIEDVLEITDDVTE
LDTWVRNAARIAVNEVVFEDGDPDEVADVLHGLVRRLANPGAAAIVKAFTLDLKDYEPPEPEDELDRLKWEYYHPRWLIE
RWMEMFGDPDEVVALLEANNRRPPLTIRVNTLKVDPEELAERLQRKYRVTVEPGRFLDEILKIPEGLPIGEMPEWEEGLF
VIQDEAAALASAVLNPKPGEVVVDLCAAPGGKTTHMAQLMGGEGKIVAIDVDEVRMERLREIAERMGVLDCIETHLMDGR
EAPEKLGREFADAVLVDPPCSADGTIPKNPERRWRITPDELERLPKFQYELLKAGAEMVKPGGRLLYSTCSMFPEEDEEV
VRRFLDEHPEFELLEVKVGDQGFDMPEACRLFPHRHETCGFFIALMGRTG

Sequences:

>Translated_450_residues
MTSRDAKTYEEAVEIVLRTLVKAERIKPTQYARRLVMKEMNPSREARSVSAGLLYSVLQKRGLLDEVIEDVLEITDDVTE
LDTWVRNAARIAVNEVVFEDGDPDEVADVLHGLVRRLANPGAAAIVKAFTLDLKDYEPPEPEDELDRLKWEYYHPRWLIE
RWMEMFGDPDEVVALLEANNRRPPLTIRVNTLKVDPEELAERLQRKYRVTVEPGRFLDEILKIPEGLPIGEMPEWEEGLF
VIQDEAAALASAVLNPKPGEVVVDLCAAPGGKTTHMAQLMGGEGKIVAIDVDEVRMERLREIAERMGVLDCIETHLMDGR
EAPEKLGREFADAVLVDPPCSADGTIPKNPERRWRITPDELERLPKFQYELLKAGAEMVKPGGRLLYSTCSMFPEEDEEV
VRRFLDEHPEFELLEVKVGDQGFDMPEACRLFPHRHETCGFFIALMGRTG
>Mature_449_residues
TSRDAKTYEEAVEIVLRTLVKAERIKPTQYARRLVMKEMNPSREARSVSAGLLYSVLQKRGLLDEVIEDVLEITDDVTEL
DTWVRNAARIAVNEVVFEDGDPDEVADVLHGLVRRLANPGAAAIVKAFTLDLKDYEPPEPEDELDRLKWEYYHPRWLIER
WMEMFGDPDEVVALLEANNRRPPLTIRVNTLKVDPEELAERLQRKYRVTVEPGRFLDEILKIPEGLPIGEMPEWEEGLFV
IQDEAAALASAVLNPKPGEVVVDLCAAPGGKTTHMAQLMGGEGKIVAIDVDEVRMERLREIAERMGVLDCIETHLMDGRE
APEKLGREFADAVLVDPPCSADGTIPKNPERRWRITPDELERLPKFQYELLKAGAEMVKPGGRLLYSTCSMFPEEDEEVV
RRFLDEHPEFELLEVKVGDQGFDMPEACRLFPHRHETCGFFIALMGRTG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=323, Percent_Identity=34.6749226006192, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI76150623, Length=323, Percent_Identity=34.6749226006192, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI8922322, Length=307, Percent_Identity=31.9218241042345, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI270288816, Length=306, Percent_Identity=31.6993464052288, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI270288818, Length=306, Percent_Identity=32.0261437908497, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI23199998, Length=306, Percent_Identity=31.6993464052288, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI32698918, Length=212, Percent_Identity=35.377358490566, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI301336155, Length=240, Percent_Identity=32.5, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI39995082, Length=267, Percent_Identity=28.8389513108614, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI11545785, Length=190, Percent_Identity=30.5263157894737, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI40316918, Length=188, Percent_Identity=34.0425531914894, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI2367212, Length=294, Percent_Identity=32.6530612244898, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI87081985, Length=296, Percent_Identity=30.4054054054054, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17536757, Length=314, Percent_Identity=30.5732484076433, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI71998419, Length=305, Percent_Identity=29.8360655737705, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115534021, Length=232, Percent_Identity=31.8965517241379, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25143471, Length=296, Percent_Identity=28.7162162162162, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324268, Length=319, Percent_Identity=31.974921630094, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324306, Length=282, Percent_Identity=28.0141843971631, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319447, Length=262, Percent_Identity=27.0992366412214, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI22024126, Length=316, Percent_Identity=29.1139240506329, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24668781, Length=247, Percent_Identity=32.7935222672065, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356579, Length=226, Percent_Identity=33.6283185840708, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21356513, Length=247, Percent_Identity=32.7935222672065, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21355201, Length=185, Percent_Identity=32.972972972973, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI19920494, Length=174, Percent_Identity=31.0344827586207, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 51125; Mature: 50994

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRDAKTYEEAVEIVLRTLVKAERIKPTQYARRLVMKEMNPSREARSVSAGLLYSVLQK
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RGLLDEVIEDVLEITDDVTELDTWVRNAARIAVNEVVFEDGDPDEVADVLHGLVRRLANP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
GAAAIVKAFTLDLKDYEPPEPEDELDRLKWEYYHPRWLIERWMEMFGDPDEVVALLEANN
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHEEHHHCCC
RRPPLTIRVNTLKVDPEELAERLQRKYRVTVEPGRFLDEILKIPEGLPIGEMPEWEEGLF
CCCCEEEEEEEEECCHHHHHHHHHHHCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEE
VIQDEAAALASAVLNPKPGEVVVDLCAAPGGKTTHMAQLMGGEGKIVAIDVDEVRMERLR
EEECHHHHHHHHHCCCCCCHHHHEECCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHH
EIAERMGVLDCIETHLMDGREAPEKLGREFADAVLVDPPCSADGTIPKNPERRWRITPDE
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCHHH
LERLPKFQYELLKAGAEMVKPGGRLLYSTCSMFPEEDEEVVRRFLDEHPEFELLEVKVGD
HHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECC
QGFDMPEACRLFPHRHETCGFFIALMGRTG
CCCCCHHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSRDAKTYEEAVEIVLRTLVKAERIKPTQYARRLVMKEMNPSREARSVSAGLLYSVLQK
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
RGLLDEVIEDVLEITDDVTELDTWVRNAARIAVNEVVFEDGDPDEVADVLHGLVRRLANP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
GAAAIVKAFTLDLKDYEPPEPEDELDRLKWEYYHPRWLIERWMEMFGDPDEVVALLEANN
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHEEHHHCCC
RRPPLTIRVNTLKVDPEELAERLQRKYRVTVEPGRFLDEILKIPEGLPIGEMPEWEEGLF
CCCCEEEEEEEEECCHHHHHHHHHHHCEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCEE
VIQDEAAALASAVLNPKPGEVVVDLCAAPGGKTTHMAQLMGGEGKIVAIDVDEVRMERLR
EEECHHHHHHHHHCCCCCCHHHHEECCCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHH
EIAERMGVLDCIETHLMDGREAPEKLGREFADAVLVDPPCSADGTIPKNPERRWRITPDE
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCHHH
LERLPKFQYELLKAGAEMVKPGGRLLYSTCSMFPEEDEEVVRRFLDEHPEFELLEVKVGD
HHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECC
QGFDMPEACRLFPHRHETCGFFIALMGRTG
CCCCCHHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]