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The map label for this gene is hemK [C]

Identifier: 20094927

GI number: 20094927

Start: 1510584

End: 1511174

Strand: Direct

Name: hemK [C]

Synonym: MK1491

Alternate gene names: 20094927

Gene position: 1510584-1511174 (Clockwise)

Preceding gene: 20094926

Following gene: 20094928

Centisome position: 89.12

GC content: 62.94

Gene sequence:

>591_bases
GTGGGGGTAGCGGTTCGGGACGTCGTCAGGTACGGGCGACTGAAGCTCCTGGTGTTCGAGAACGTGTACCCGCCTGCCGA
GGATTCGTTCCTACTCGCCGAGCACCAAGGGGTATCCGGCTCCGAGCGGGTCTTGGACGTCGGGACGGGATGCGGCATTC
AAGGGTTATCGGCGGCCGCGAAAGGCTGTGAGGTGGTAGCGACGGACGTCAACCCCGCGGCCGTCCACTGCGCACGGTGG
AACGCCCACCTCAACGACCTGAACATCGACGTTCGTGTGGGAGACCTGTTCGAGCCCGTCCGCGATGAGCGGTTCGACAT
CGTCCTGTTCAACCCACCTTACCTACCCGGCCGTGAACTGCCCGGAAGCGATCCCATTTCCCGAGCCACCGAAGACCCCG
CCGTCATCCGCCGCTTCCTAAAAGATCTCCTCCGGGAAGAGATTCGCTGGGACGAGGCTAGGATCGTCGTGTCCAGCCTG
ACCCCGAAGAAGTACCTGGAACCCCTGCAGCGTTTCGAGGTGGAAATCGTGGCCGAGGAACCCCTGTTTTTCGAGAAGAT
CCGCGTGCTCGCGCTTCGACCGTCCCGATGA

Upstream 100 bases:

>100_bases
ATAGGACGGAGGTGATCGGGTCAGCACCCTCGGGACATCTCATCCCGATCCCGGTCGAGCTGGGGCTAATCTCCATCATC
CCCGAGAGCGGGTGGATCCC

Downstream 100 bases:

>100_bases
AATTTGTGCGAGCGTAGTGAGGAGAGCGACACGGTAATCTTCCGACAGTCAACACCACCTCCGCGGGGGTGAGCCGGTTG
TTCGTCGTCGTCTACTCGAC

Product: rRNA/ tRNA methylase

Products: NA

Alternate protein names: M.MjaHemkP [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MGVAVRDVVRYGRLKLLVFENVYPPAEDSFLLAEHQGVSGSERVLDVGTGCGIQGLSAAAKGCEVVATDVNPAAVHCARW
NAHLNDLNIDVRVGDLFEPVRDERFDIVLFNPPYLPGRELPGSDPISRATEDPAVIRRFLKDLLREEIRWDEARIVVSSL
TPKKYLEPLQRFEVEIVAEEPLFFEKIRVLALRPSR

Sequences:

>Translated_196_residues
MGVAVRDVVRYGRLKLLVFENVYPPAEDSFLLAEHQGVSGSERVLDVGTGCGIQGLSAAAKGCEVVATDVNPAAVHCARW
NAHLNDLNIDVRVGDLFEPVRDERFDIVLFNPPYLPGRELPGSDPISRATEDPAVIRRFLKDLLREEIRWDEARIVVSSL
TPKKYLEPLQRFEVEIVAEEPLFFEKIRVLALRPSR
>Mature_195_residues
GVAVRDVVRYGRLKLLVFENVYPPAEDSFLLAEHQGVSGSERVLDVGTGCGIQGLSAAAKGCEVVATDVNPAAVHCARWN
AHLNDLNIDVRVGDLFEPVRDERFDIVLFNPPYLPGRELPGSDPISRATEDPAVIRRFLKDLLREEIRWDEARIVVSSLT
PKKYLEPLQRFEVEIVAEEPLFFEKIRVLALRPSR

Specific function: Putative protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Caenorhabditis elegans, GI193204212, Length=124, Percent_Identity=37.0967741935484, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004557
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 22003; Mature: 21872

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVAVRDVVRYGRLKLLVFENVYPPAEDSFLLAEHQGVSGSERVLDVGTGCGIQGLSAAA
CCCHHHHHHHHCCEEEEEEECCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCHHHHHC
KGCEVVATDVNPAAVHCARWNAHLNDLNIDVRVGDLFEPVRDERFDIVLFNPPYLPGREL
CCCEEEEECCCCHHEEEEECCCCCCCEEEEEEECHHHHHHCCCCEEEEEECCCCCCCCCC
PGSDPISRATEDPAVIRRFLKDLLREEIRWDEARIVVSSLTPKKYLEPLQRFEVEIVAEE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHCEEEEEECC
PLFFEKIRVLALRPSR
CHHHHHEEEEEECCCC
>Mature Secondary Structure 
GVAVRDVVRYGRLKLLVFENVYPPAEDSFLLAEHQGVSGSERVLDVGTGCGIQGLSAAA
CCHHHHHHHHCCEEEEEEECCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCHHHHHC
KGCEVVATDVNPAAVHCARWNAHLNDLNIDVRVGDLFEPVRDERFDIVLFNPPYLPGREL
CCCEEEEECCCCHHEEEEECCCCCCCEEEEEEECHHHHHHCCCCEEEEEECCCCCCCCCC
PGSDPISRATEDPAVIRRFLKDLLREEIRWDEARIVVSSLTPKKYLEPLQRFEVEIVAEE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHCEEEEEECC
PLFFEKIRVLALRPSR
CHHHHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]