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The map label for this gene is rpa [H]

Identifier: 20094877

GI number: 20094877

Start: 1473643

End: 1474941

Strand: Direct

Name: rpa [H]

Synonym: MK1441

Alternate gene names: 20094877

Gene position: 1473643-1474941 (Clockwise)

Preceding gene: 20094875

Following gene: 20094878

Centisome position: 86.94

GC content: 60.89

Gene sequence:

>1299_bases
GTGCCAAGGTCTAGAGGGGCGATCCTGACCTCGGACATCGACCGGTTGGTAGAAAAGCTGGCTGAAGAGGTCGGAAAGCG
CGAGGAGGAGGTGCGCCGGGAGATCAACAGACTCCGGAAACGATGGGGAGTGTCGGAGCTCGGCGCGCTTCTCGCCCTCG
CCGACCGGATGGGTGTGAAGCTGATGCGAACGGGAGAGGAAAAACCGGGGAGAGTGACGCTGGATGAAGCCATCTCCCGG
GGACTGCAGTCCTTCGACACGGAGTTCATCGTCGTACGCGTGTCGGACCCCGCGAAGACCAGGTCGGGCGGTAAAATGGT
GACCTTGGTGGTGGGGGACGAGACGCGGTCCGCCGCGTTGGTAGCGTTCGACGAGGCCGTCGAGACACTCGAGGAACTCG
AGGAGGGTGATGTGGTACGGGCTAGGAACTTGACTGTGAGTTCGTTCCGTAACAGTCCACAGCTGGTGGTCACTCGAGAG
ACCGAGCTTGAAGTCGTAGGCTCCGAGGAGGATCCGAACCGGATCATCGAGCGGAACATCTCCGAGGTGAAACACGGAGA
GTACGTGCGCGTGCGAGGTGTCGTGGCGAGCGAGCCCGTCGATACGGGAGAACGCGTATACTTCTGGCTCTCCGACGAGA
CAGGCTCGACGCGTGTTAACCTGTGGGGTGAGGAGGCCGAGCGTGCGCTGGACCTCGACTACGGCGACGGTGTGATCGTG
GAAGGGTGGGTCTCTACCCGCGGTGATCACCCGACGATCAACATACTCAGAACCCAAGGTCGTGTGGAGCCCGCTGAGGT
TTCCATCAAACCAGCTATCCGGAAGCGTGTCGAGGAGCTCGGTAAGGGGGATGTGGCGGAGGTATCAGGCGTTATCGTCG
CCGTATACGCACGTCGTCGGTACTACGAGGCGTGCCCCACCTGCGGTCGGGCCATGAGGAAGGGAGAGTGTCCCGAGCAC
GGGGCCGTGGAACCCGAACGGAGACCCGTGCTGAACGTGGTCGTAGACGACGGTACCGGGACGGTAAGGACGGTGTTCTT
CGGGGAACACGCGGTCGAGTTCGCGGGATACGAGACCACGAGGGAATACCTGGAAGCCGACGAATCCGACATCGAAAAGA
GACTTTTAGGTGAAAGTGTTTCCGTAGTGCTCAGAGTTCGGGGAGAAGGGGTCGTAGAGGACTACGATGCCGTCGCACTG
CGGGCTAGGATACTCAACGAGGAGGACTTCAAACGCGAAATCCCGATCTTGGTCCGGGAGCTGAAGGGGGAGGAGAGTGA
AGGAGAGGAAGCTGAGTGA

Upstream 100 bases:

>100_bases
CTTCTCGGCCATCGTCTTCCCCACGGTGCTCGACCCCCGGCCGCCCCCGAGCGGCGGTTGAAAAAGGATCGGGGACCCGA
GCCCCGTATATCAGGTGGAA

Downstream 100 bases:

>100_bases
TCTGGACCTACTGCCCGATGAAACCGTCAAAAAGCTGGAAGAGAAGGGGATCGTGACGGTCGAGGACTTCATTTACGCCG
ATCCGAAGTACCTGTCGGAG

Product: replication factor A (ssDNA-binding protein)

Products: NA

Alternate protein names: RF-A; RP-A; Replication factor A protein 1; Single-stranded DNA-binding protein; mjaSSB [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MPRSRGAILTSDIDRLVEKLAEEVGKREEEVRREINRLRKRWGVSELGALLALADRMGVKLMRTGEEKPGRVTLDEAISR
GLQSFDTEFIVVRVSDPAKTRSGGKMVTLVVGDETRSAALVAFDEAVETLEELEEGDVVRARNLTVSSFRNSPQLVVTRE
TELEVVGSEEDPNRIIERNISEVKHGEYVRVRGVVASEPVDTGERVYFWLSDETGSTRVNLWGEEAERALDLDYGDGVIV
EGWVSTRGDHPTINILRTQGRVEPAEVSIKPAIRKRVEELGKGDVAEVSGVIVAVYARRRYYEACPTCGRAMRKGECPEH
GAVEPERRPVLNVVVDDGTGTVRTVFFGEHAVEFAGYETTREYLEADESDIEKRLLGESVSVVLRVRGEGVVEDYDAVAL
RARILNEEDFKREIPILVRELKGEESEGEEAE

Sequences:

>Translated_432_residues
MPRSRGAILTSDIDRLVEKLAEEVGKREEEVRREINRLRKRWGVSELGALLALADRMGVKLMRTGEEKPGRVTLDEAISR
GLQSFDTEFIVVRVSDPAKTRSGGKMVTLVVGDETRSAALVAFDEAVETLEELEEGDVVRARNLTVSSFRNSPQLVVTRE
TELEVVGSEEDPNRIIERNISEVKHGEYVRVRGVVASEPVDTGERVYFWLSDETGSTRVNLWGEEAERALDLDYGDGVIV
EGWVSTRGDHPTINILRTQGRVEPAEVSIKPAIRKRVEELGKGDVAEVSGVIVAVYARRRYYEACPTCGRAMRKGECPEH
GAVEPERRPVLNVVVDDGTGTVRTVFFGEHAVEFAGYETTREYLEADESDIEKRLLGESVSVVLRVRGEGVVEDYDAVAL
RARILNEEDFKREIPILVRELKGEESEGEEAE
>Mature_431_residues
PRSRGAILTSDIDRLVEKLAEEVGKREEEVRREINRLRKRWGVSELGALLALADRMGVKLMRTGEEKPGRVTLDEAISRG
LQSFDTEFIVVRVSDPAKTRSGGKMVTLVVGDETRSAALVAFDEAVETLEELEEGDVVRARNLTVSSFRNSPQLVVTRET
ELEVVGSEEDPNRIIERNISEVKHGEYVRVRGVVASEPVDTGERVYFWLSDETGSTRVNLWGEEAERALDLDYGDGVIVE
GWVSTRGDHPTINILRTQGRVEPAEVSIKPAIRKRVEELGKGDVAEVSGVIVAVYARRRYYEACPTCGRAMRKGECPEHG
AVEPERRPVLNVVVDDGTGTVRTVFFGEHAVEFAGYETTREYLEADESDIEKRLLGESVSVVLRVRGEGVVEDYDAVALR
ARILNEEDFKREIPILVRELKGEESEGEEAE

Specific function: Probably plays an essential for replication of the chromosome, DNA recombination and repair [H]

COG id: COG1599

COG function: function code L; Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 OB DNA-binding domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- InterPro:   IPR013955 [H]

Pfam domain/function: PF08646 Rep_fac-A_C; PF01336 tRNA_anti [H]

EC number: NA

Molecular weight: Translated: 48238; Mature: 48107

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRSRGAILTSDIDRLVEKLAEEVGKREEEVRREINRLRKRWGVSELGALLALADRMGVK
CCCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEE
LMRTGEEKPGRVTLDEAISRGLQSFDTEFIVVRVSDPAKTRSGGKMVTLVVGDETRSAAL
EEECCCCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCEEE
VAFDEAVETLEELEEGDVVRARNLTVSSFRNSPQLVVTRETELEVVGSEEDPNRIIERNI
EEHHHHHHHHHHHHCCCEEEECCCCHHHHCCCCCEEEEECCEEEEECCCCCHHHHHHCCH
SEVKHGEYVRVRGVVASEPVDTGERVYFWLSDETGSTRVNLWGEEAERALDLDYGDGVIV
HHHCCCCEEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEEECHHHHHEEECCCCCCEEE
EGWVSTRGDHPTINILRTQGRVEPAEVSIKPAIRKRVEELGKGDVAEVSGVIVAVYARRR
EEHCCCCCCCCEEEEEECCCCCCHHHEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YYEACPTCGRAMRKGECPEHGAVEPERRPVLNVVVDDGTGTVRTVFFGEHAVEFAGYETT
HHHHCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCHHHHHCCHHHH
REYLEADESDIEKRLLGESVSVVLRVRGEGVVEDYDAVALRARILNEEDFKREIPILVRE
HHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
LKGEESEGEEAE
HCCCCCCCCCCC
>Mature Secondary Structure 
PRSRGAILTSDIDRLVEKLAEEVGKREEEVRREINRLRKRWGVSELGALLALADRMGVK
CCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCEE
LMRTGEEKPGRVTLDEAISRGLQSFDTEFIVVRVSDPAKTRSGGKMVTLVVGDETRSAAL
EEECCCCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEEEECCCCCCEEE
VAFDEAVETLEELEEGDVVRARNLTVSSFRNSPQLVVTRETELEVVGSEEDPNRIIERNI
EEHHHHHHHHHHHHCCCEEEECCCCHHHHCCCCCEEEEECCEEEEECCCCCHHHHHHCCH
SEVKHGEYVRVRGVVASEPVDTGERVYFWLSDETGSTRVNLWGEEAERALDLDYGDGVIV
HHHCCCCEEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEEECHHHHHEEECCCCCCEEE
EGWVSTRGDHPTINILRTQGRVEPAEVSIKPAIRKRVEELGKGDVAEVSGVIVAVYARRR
EEHCCCCCCCCEEEEEECCCCCCHHHEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
YYEACPTCGRAMRKGECPEHGAVEPERRPVLNVVVDDGTGTVRTVFFGEHAVEFAGYETT
HHHHCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCHHHHHCCHHHH
REYLEADESDIEKRLLGESVSVVLRVRGEGVVEDYDAVALRARILNEEDFKREIPILVRE
HHHHCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
LKGEESEGEEAE
HCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087; 9843941 [H]