Click here to switch to the map view.

The map label for this gene is pqqE [H]

Identifier: 20094332

GI number: 20094332

Start: 844704

End: 846110

Strand: Reverse

Name: pqqE [H]

Synonym: MK0896

Alternate gene names: 20094332

Gene position: 846110-844704 (Counterclockwise)

Preceding gene: 20094333

Following gene: 20094331

Centisome position: 49.92

GC content: 66.95

Gene sequence:

>1407_bases
ATGACCAGGGTCGGTGAGTTCATCCGTGTGCTGAACCGGGTGCTGGACTCGGAGCTGGCACGGCGGCTGATGAAGCTGGG
GGCCAAGCGGTGCGAGTCGTGCGGAGACGTGCGCGTGAAGGTCGCGCTGGACGTGGCTTATGGCGGTCGGGAGGACGCGT
GCTGGAAGTGCAAGGCGACGGCTCGATTGGTGAAGAAGCTCGTTGAGAAGACGGCCCGGGCGGCCGGCGTAGACGAGGAG
ACAGTCCGGGAGGCCCTCTCGCTGGACTCCTACCGGCGAGGCATCGCCGTGACGCTGCTAGGGATCTACCGGTACGGGGT
CCGGAAACCGTTCGTCCCGGCCGCTCCGTATCTCGTGGTCTGGGACGTGACCGGGCTGTGTAACCTGCGCTGCGAGCACT
GCTACTCGGAGGCGGGCAAGCCCGCGCCCGGCGAGCTGGACACCGAGAGGGCGCTGGAAGTCATCGAGCGGTTCTCAGAG
TGGAACGTTCCGGGGCTGGCGTTCTCCGGCGGCGAGCCGCTGATGCGGGACGACTTCTTCGAGCTGGCGGAGGCCTCCGC
CAACGAGGGGATGTTCACCGCGCTCGCCACGAACGGGACCCTGATCGACCGGGACACGGCGGAGCGGCTGGAGGCCGCGG
GCGTCGAGTACGTCGAGATCAGCCTGGACGGGGCTCGGCCCGAGACGCACGATAAGTTCCGAGGCGTCAAGGGTGCCTGG
GAACGAACGGTTGAGGGCGTTCGTCACTGCGCCGAGACGGACATGATCACCGTGATCGCCTTCACCGTGCACCGGAACAA
CGTGGACGAGCTCCCGCAGATGCTGGATCTCGCGGAGGAGCTCGGAGCCGACGGGATCGCAGTGTTCAACTTCATCCCCA
CGGGCCAGGGTCGGTTCTGCCCGGAGCTGGACCCGCCGCCTGAGGTCCGGGAGGAGGTGCTCAAGATGCTCGTTCGGGAG
GCCCTGGACCGGGACCTGATGATCTACTCCACCGCGCCGCAGATGTCCCGAGTGAGCCTGCAGATGACCGAGTCGGGGGA
GGGAGGCGTACTCTACGGAACCCACTTCGCGTACGCGGGCGAGGGCCGCTGGATCGAGCCCCTCGTCGAGTTTATCGGGG
GGTGCGGCGCCGGCCGATGCCTGCTGGCCATCCGGCCGAACGGTGACGTCCAGCCGTGCGTGTTCTTGCCAGTTAAGATC
GGGAACATACTGGAGGACGATCCGGAGGAGTTGTGGGAACACGAGGTGCTCTGGGCGTGCCGAAACCGTGACGAGCTGGA
GAAGCCCTGCGGCGAGTGCAAGTACCGGTACGTGTGCGGCGGATGCCGGGCCCGTGCGTACGCGATCACGGGCAAGGTGG
AGGGGCCCGACCCGGGCTGTGTCCTAGTGGGGGATGCTAACAAGTGA

Upstream 100 bases:

>100_bases
AGGAGATAGTGGAGATCATTCGGGAGGCGGGCTTCACCCCCGTGCAGCGCACCACGCTCTACGAGCCGGTGAAGGTGTAC
TAAGGTAGGGGGCGCTTCGC

Downstream 100 bases:

>100_bases
AAGTCTTGTTGGTTCAACCTCCGTTCGAGGACGACATCGCCCGCGTGCTGGGAGTACGGGGATTCCCGATCGGACTAGTC
TACCTGGCCGCCAAGCTCGA

Product: Fe-S oxidoreductase

Products: NA

Alternate protein names: Pyrroloquinoline quinone biosynthesis protein E [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MTRVGEFIRVLNRVLDSELARRLMKLGAKRCESCGDVRVKVALDVAYGGREDACWKCKATARLVKKLVEKTARAAGVDEE
TVREALSLDSYRRGIAVTLLGIYRYGVRKPFVPAAPYLVVWDVTGLCNLRCEHCYSEAGKPAPGELDTERALEVIERFSE
WNVPGLAFSGGEPLMRDDFFELAEASANEGMFTALATNGTLIDRDTAERLEAAGVEYVEISLDGARPETHDKFRGVKGAW
ERTVEGVRHCAETDMITVIAFTVHRNNVDELPQMLDLAEELGADGIAVFNFIPTGQGRFCPELDPPPEVREEVLKMLVRE
ALDRDLMIYSTAPQMSRVSLQMTESGEGGVLYGTHFAYAGEGRWIEPLVEFIGGCGAGRCLLAIRPNGDVQPCVFLPVKI
GNILEDDPEELWEHEVLWACRNRDELEKPCGECKYRYVCGGCRARAYAITGKVEGPDPGCVLVGDANK

Sequences:

>Translated_468_residues
MTRVGEFIRVLNRVLDSELARRLMKLGAKRCESCGDVRVKVALDVAYGGREDACWKCKATARLVKKLVEKTARAAGVDEE
TVREALSLDSYRRGIAVTLLGIYRYGVRKPFVPAAPYLVVWDVTGLCNLRCEHCYSEAGKPAPGELDTERALEVIERFSE
WNVPGLAFSGGEPLMRDDFFELAEASANEGMFTALATNGTLIDRDTAERLEAAGVEYVEISLDGARPETHDKFRGVKGAW
ERTVEGVRHCAETDMITVIAFTVHRNNVDELPQMLDLAEELGADGIAVFNFIPTGQGRFCPELDPPPEVREEVLKMLVRE
ALDRDLMIYSTAPQMSRVSLQMTESGEGGVLYGTHFAYAGEGRWIEPLVEFIGGCGAGRCLLAIRPNGDVQPCVFLPVKI
GNILEDDPEELWEHEVLWACRNRDELEKPCGECKYRYVCGGCRARAYAITGKVEGPDPGCVLVGDANK
>Mature_467_residues
TRVGEFIRVLNRVLDSELARRLMKLGAKRCESCGDVRVKVALDVAYGGREDACWKCKATARLVKKLVEKTARAAGVDEET
VREALSLDSYRRGIAVTLLGIYRYGVRKPFVPAAPYLVVWDVTGLCNLRCEHCYSEAGKPAPGELDTERALEVIERFSEW
NVPGLAFSGGEPLMRDDFFELAEASANEGMFTALATNGTLIDRDTAERLEAAGVEYVEISLDGARPETHDKFRGVKGAWE
RTVEGVRHCAETDMITVIAFTVHRNNVDELPQMLDLAEELGADGIAVFNFIPTGQGRFCPELDPPPEVREEVLKMLVREA
LDRDLMIYSTAPQMSRVSLQMTESGEGGVLYGTHFAYAGEGRWIEPLVEFIGGCGAGRCLLAIRPNGDVQPCVFLPVKIG
NILEDDPEELWEHEVLWACRNRDELEKPCGECKYRYVCGGCRARAYAITGKVEGPDPGCVLVGDANK

Specific function: Together With Moac, Is Involved In The Conversion Of A Guanosine Derivative (Gxp) Into Molybdopterin Precursor Z. [C]

COG id: COG0535

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. PqqE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR000385
- InterPro:   IPR017200
- InterPro:   IPR011843
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 51735; Mature: 51603

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVGEFIRVLNRVLDSELARRLMKLGAKRCESCGDVRVKVALDVAYGGREDACWKCKAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEHHHH
ARLVKKLVEKTARAAGVDEETVREALSLDSYRRGIAVTLLGIYRYGVRKPFVPAAPYLVV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEE
WDVTGLCNLRCEHCYSEAGKPAPGELDTERALEVIERFSEWNVPGLAFSGGEPLMRDDFF
EECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHH
ELAEASANEGMFTALATNGTLIDRDTAERLEAAGVEYVEISLDGARPETHDKFRGVKGAW
HHHHCCCCCCEEEEEECCCEEECCCHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCCHHH
ERTVEGVRHCAETDMITVIAFTVHRNNVDELPQMLDLAEELGADGIAVFNFIPTGQGRFC
HHHHHHHHHHHHCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCC
PELDPPPEVREEVLKMLVREALDRDLMIYSTAPQMSRVSLQMTESGEGGVLYGTHFAYAG
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCCEEEECEEEECC
EGRWIEPLVEFIGGCGAGRCLLAIRPNGDVQPCVFLPVKIGNILEDDPEELWEHEVLWAC
CCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
RNRDELEKPCGECKYRYVCGGCRARAYAITGKVEGPDPGCVLVGDANK
CCCHHHHCCHHHCCEEEEECCCCEEEEEEEEEECCCCCCEEEEECCCC
>Mature Secondary Structure 
TRVGEFIRVLNRVLDSELARRLMKLGAKRCESCGDVRVKVALDVAYGGREDACWKCKAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEHHHH
ARLVKKLVEKTARAAGVDEETVREALSLDSYRRGIAVTLLGIYRYGVRKPFVPAAPYLVV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCEEEE
WDVTGLCNLRCEHCYSEAGKPAPGELDTERALEVIERFSEWNVPGLAFSGGEPLMRDDFF
EECCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHH
ELAEASANEGMFTALATNGTLIDRDTAERLEAAGVEYVEISLDGARPETHDKFRGVKGAW
HHHHCCCCCCEEEEEECCCEEECCCHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCCHHH
ERTVEGVRHCAETDMITVIAFTVHRNNVDELPQMLDLAEELGADGIAVFNFIPTGQGRFC
HHHHHHHHHHHHCCEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCC
PELDPPPEVREEVLKMLVREALDRDLMIYSTAPQMSRVSLQMTESGEGGVLYGTHFAYAG
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCCEEEECEEEECC
EGRWIEPLVEFIGGCGAGRCLLAIRPNGDVQPCVFLPVKIGNILEDDPEELWEHEVLWAC
CCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHH
RNRDELEKPCGECKYRYVCGGCRARAYAITGKVEGPDPGCVLVGDANK
CCCHHHHCCHHHCCEEEEECCCCEEEEEEEEEECCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA