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The map label for this gene is EriC

Identifier: 20094308

GI number: 20094308

Start: 824222

End: 825364

Strand: Reverse

Name: EriC

Synonym: MK0872

Alternate gene names: NA

Gene position: 825364-824222 (Counterclockwise)

Preceding gene: 20094322

Following gene: 20094307

Centisome position: 48.69

GC content: 61.85

Gene sequence:

>1143_bases
TTGCCGTCGACGGGGGCGTTGATTCACGTCGCCCGGTGGACGGTTTTGGCCGCGGCGTTGGGCGTTGTCGGCGGAGCGTG
TGCTGTCGCCATCTCCTCAATTATAAGCACGGTGGAGAAGGCCGTCGGGAACGAGCCGTTAGTTATCCCGGCGTTCATGC
TGCTGGCCGGCAGCCTAGCGGCACTACATCCCGAGCTCCGAGGGACCGGGATGGAGATCATCGTCCGGGGGTTCCCAAAC
GAGCCCGCGAATCCCATCAGAGGGATGGCGAAGTTGGTACTCGCGGGTCTCGTCATCGGCGGGGGAGGTAGTGGCGGTCA
AGTAGGACCTTGTGCCCAGGCGTGCGCGTCCGTAGGGGGCTACGTAGCTTCGAAGCTGGGAATGTCGGAGATGGAAAGAA
AATGGGCCGTGCTGGGGGTAATTTCGGGAGGCGTGGCCGGGGTTCTGTGCGCACCGCTGGCGGCGGCCCTGTTCGCCATC
GAGGTCCTTCGCGTGAGGTCCCGCTACGTCGTACTTTTTCCCAGCACGATAGCCAGTCTTGCCGGATACTCCGTGTACGT
TTCGACCTTAGGAAAGCGCTACTTGCTCGTGAGGAACGCCCCTTATCACTACAGCCCACAGCACCTGCCGGAACTCCTGG
TGATCGCCGTAGTGGCGACGTTACTCGCATACGTGTACAGCCGGTGCGTCAAGGAAGCCCGTCGTCTGTTCGTCGAATCC
GTACCTAGTCAACCCGTACGTTCTCTCCTAGCAGGACTCGGGGTAGCGTCGGTAGGCATCGCTATTCCGACAGCCGTAGG
ATTGGGGTTGGACTACGCCTCGAAGGCCGCCTTAGGCCGCATCGGAGCCGAAGAAGCGCTACTATCGTTCCTGGGCAAAA
TGGTAGCCACCGCGCTAACAGTCGGTAGTGAAACACCCGCGGGCTTGGTTTCACCGACAGTGTGCGTGGGCGCGTTTTTG
GGTCTTTTCTGGGTCAAACGTTGGGCCCGTCCGCTCCGGCCGGAACCGCGACGGCTATCGCTGCGTTCTTGGCTGCGACG
TTCAACGCTCCGATCTCGTCCGCTGTGCTGGTCATCGAGCTGTTCGGCATCGACTGCGCCGTCCCGGCCGCTTTGGGAGC
GATCCTGGGGTATCAGCTCTTGA

Upstream 100 bases:

>100_bases
TCATTTGAGTACAACTCTCGCACGCGTCCGCACGGTCCGCGTTCCCCCTCAGCACTTACCGTCAGGGTCCACACCGCCGA
GAACCCCCGGAGGTGGAGAG

Downstream 100 bases:

>100_bases
AACCCGAGGTAGTCATCGAACTGAAGAGGAGGTGATCCGGTGTGTACGAGGTAGAGGTTAAGGTCAAGCTGAAGAACCCC
GAAGACGTGCGGAAGCGCTT

Product: chloride channel protein EriC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MPSTGALIHVARWTVLAAALGVVGGACAVAISSIISTVEKAVGNEPLVIPAFMLLAGSLAALHPELRGTGMEIIVRGFPN
EPANPIRGMAKLVLAGLVIGGGGSGGQVGPCAQACASVGGYVASKLGMSEMERKWAVLGVISGGVAGVLCAPLAAALFAI
EVLRVRSRYVVLFPSTIASLAGYSVYVSTLGKRYLLVRNAPYHYSPQHLPELLVIAVVATLLAYVYSRCVKEARRLFVES
VPSQPVRSLLAGLGVASVGIAIPTAVGLGLDYASKAALGRIGAEEALLSFLGKMVATALTVGSETPAGLVSPTVCVGAFL
GLFWVKRWARPLRPEPRRLSLRSWLRRSTLRSRPLCWSSSCSASTAPSRPLWERSWGISS

Sequences:

>Translated_380_residues
MPSTGALIHVARWTVLAAALGVVGGACAVAISSIISTVEKAVGNEPLVIPAFMLLAGSLAALHPELRGTGMEIIVRGFPN
EPANPIRGMAKLVLAGLVIGGGGSGGQVGPCAQACASVGGYVASKLGMSEMERKWAVLGVISGGVAGVLCAPLAAALFAI
EVLRVRSRYVVLFPSTIASLAGYSVYVSTLGKRYLLVRNAPYHYSPQHLPELLVIAVVATLLAYVYSRCVKEARRLFVES
VPSQPVRSLLAGLGVASVGIAIPTAVGLGLDYASKAALGRIGAEEALLSFLGKMVATALTVGSETPAGLVSPTVCVGAFL
GLFWVKRWARPLRPEPRRLSLRSWLRRSTLRSRPLCWSSSCSASTAPSRPLWERSWGISS
>Mature_379_residues
PSTGALIHVARWTVLAAALGVVGGACAVAISSIISTVEKAVGNEPLVIPAFMLLAGSLAALHPELRGTGMEIIVRGFPNE
PANPIRGMAKLVLAGLVIGGGGSGGQVGPCAQACASVGGYVASKLGMSEMERKWAVLGVISGGVAGVLCAPLAAALFAIE
VLRVRSRYVVLFPSTIASLAGYSVYVSTLGKRYLLVRNAPYHYSPQHLPELLVIAVVATLLAYVYSRCVKEARRLFVESV
PSQPVRSLLAGLGVASVGIAIPTAVGLGLDYASKAALGRIGAEEALLSFLGKMVATALTVGSETPAGLVSPTVCVGAFLG
LFWVKRWARPLRPEPRRLSLRSWLRRSTLRSRPLCWSSSCSASTAPSRPLWERSWGISS

Specific function: Unknown

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 39653; Mature: 39522

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTGALIHVARWTVLAAALGVVGGACAVAISSIISTVEKAVGNEPLVIPAFMLLAGSLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ALHPELRGTGMEIIVRGFPNEPANPIRGMAKLVLAGLVIGGGGSGGQVGPCAQACASVGG
HHCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
YVASKLGMSEMERKWAVLGVISGGVAGVLCAPLAAALFAIEVLRVRSRYVVLFPSTIASL
HHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHH
AGYSVYVSTLGKRYLLVRNAPYHYSPQHLPELLVIAVVATLLAYVYSRCVKEARRLFVES
HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPSQPVRSLLAGLGVASVGIAIPTAVGLGLDYASKAALGRIGAEEALLSFLGKMVATALT
CCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VGSETPAGLVSPTVCVGAFLGLFWVKRWARPLRPEPRRLSLRSWLRRSTLRSRPLCWSSS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
CSASTAPSRPLWERSWGISS
CCCCCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
PSTGALIHVARWTVLAAALGVVGGACAVAISSIISTVEKAVGNEPLVIPAFMLLAGSLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ALHPELRGTGMEIIVRGFPNEPANPIRGMAKLVLAGLVIGGGGSGGQVGPCAQACASVGG
HHCHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
YVASKLGMSEMERKWAVLGVISGGVAGVLCAPLAAALFAIEVLRVRSRYVVLFPSTIASL
HHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHH
AGYSVYVSTLGKRYLLVRNAPYHYSPQHLPELLVIAVVATLLAYVYSRCVKEARRLFVES
HHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPSQPVRSLLAGLGVASVGIAIPTAVGLGLDYASKAALGRIGAEEALLSFLGKMVATALT
CCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VGSETPAGLVSPTVCVGAFLGLFWVKRWARPLRPEPRRLSLRSWLRRSTLRSRPLCWSSS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
CSASTAPSRPLWERSWGISS
CCCCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]