Click here to switch to the map view.

The map label for this gene is AdeC

Identifier: 20094265

GI number: 20094265

Start: 787632

End: 789431

Strand: Reverse

Name: AdeC

Synonym: MK0829

Alternate gene names: 20094265

Gene position: 789431-787632 (Counterclockwise)

Preceding gene: 20094266

Following gene: 20094255

Centisome position: 46.57

GC content: 60.72

Gene sequence:

>1800_bases
ATGGCCCGGTCGAACCGGCGCGGGGGACGCGGGGATCCCGAGGATGATCCCGCGTGGGCTCCGCCGGGCCACAGGTGTGC
GGGTGAGAGGGCCGTCGGTGGCCCGACCGTGATCCCGCGCGCCTACCTCCCTGCTGTACCCGCGGGGGGAAACGAGTCGC
GAGCGTTCCAAGGTCGATTCGTTGACCCTTGGTTCTCGGGAATTCGAACCGGGTACGTGATCTGGGACGGAGGTAGGCTG
CTTGGAGTGACGCGAAATGAGCCCGAGCACGCCGATGTGATCGACGTTGACGGGATCATCTGCCCTGGGTTCGTGGACGC
TCATGTCCACGTGGAAAGTTCCGGACTGAGGCCGGCCCGATACGCCGAAATCGTCGTACGTGAAGGCACCACGGCCGTCG
TTTGGGACCCTCACGAGGTCGTGAACGTCTCAGGCGAGCTCGGACTTGAATGGGCCGTCAAGACCGCGGAAGAAGCCCTG
CCGTTTAAGTTCTACATCGCGCTACCGTCGTGCGTCCCGGCACTAGGGCCTCCCTACGAGACCGTGGAAGGCGAGATCAC
GGTCGACGTGGCTCGAAAGTTTGCGAGCCATCCCATGGTAGTTTCCGTAGGAGAGCTGATGGACGTCGCTGGAGTCATGG
AGGGAGAAAAGGACGAGTTCATCGAGCTGAAGAGCCTGTACGGTCTGACGGTAGACGGACACGCCCCCGGCCTCACAGGG
TTCGAAGCGATGCGATACTTCGCGGCCGGTCCTGAGACCGATCACGAGTGCTCGACCGCGGAAGAATTCACCTCAAGACG
AGAGCTCGGAGTCTGGACCTTCGTCCGACAGGGCTCATCCTCGAAGGACATGGAAGTAGCACTGGAAACGTTGGAGGACC
TCCGCGGTGTGTGCTTCGTTACCGACGATCTGCACGTTAAGGACATGGACGAAATATCACTCCGGAAAATAGTAGGGCGT
GCGATCGAGGCGGGTTTCGATCCGCTGGAGTCCCTCAGCGCGGTCACGTTGAATCCGTCCCTGTGTTACGGCTTACAATC
AGGACGTTTGGTACCAGGGTTCCATGCCGACATAGTGGTGGTCGAAGATCTCGACGAGAACATGGAACTCACGGACGTGT
GGATCGGAGGCAAACGTTCGGAACGTGTCCGGTTCCGAGACGCGGAGGCCGAATTACCCGACGTCGAGCTCTCCGTCGAC
CCGAGAGAAGTATCGTTTCAGGACGGGAAATACGAGGTCAGGTGCGTTGGGCTGGTGAGAGGTTCCATTCGCACGGAAGA
AATCGTACGAGAGATCACCGTCAAGGACGGAGCGGTGAAGGACGACGACGTGGCGTTTCTGGTCGTGACGGACCGATACG
GGCAGGGCAGCTGGTCGATAGGGTTCGTGGAAGGGTTCGAGGAACTCGACTGTGCCGTGGTGTCCACGGTAGCTCACGAC
TCACACAACGTGGTGGTCGCGGGTAGACGCCTCGATGACGTGCGCAGGGCTCTGCAGCTCGTCTCCGAGGTGGGAGGGTG
CGTAGGGGCCGTCGCGGGAGACCGAGCCGAGTTCGTACGACTGGACGTGGCGGGATTGATGAGCTCCTCGGACCCCGAGG
AGGTGAAGAAATCCTACGAGGACGTGCTCGAGTTGATTCGATCGAGTTCCGGTGTCGATTGGGATCCGTTCCAGGCTCTA
TCTTTCGTGACCCTTCCGGTGGTCCCGGAACTGAGGCTCACGGATCGAGGGTTAGTGAAGGTAGAACCGGACGAGATCCG
CTTCGTCGACATAATCACTGACGGGGATCCAGTCGAGTGA

Upstream 100 bases:

>100_bases
ACATCGATTCTGTACCACTTCCTGGTAACTTCCTGCCTGTACATCCGAAATCTGAGGAAACTAGCGGTAAGTTCATAGGT
CTCCTTCCCTACCGAGCACC

Downstream 100 bases:

>100_bases
TCTTAGCGGGACGGGTGGCCAGAGAGCCGTTGGGCCTGTAGACAGTGTGACGAAGCCACCGTTTGTCATCGCGTTCGGGA
TAATCCGACCGATAGTGAGC

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MARSNRRGGRGDPEDDPAWAPPGHRCAGERAVGGPTVIPRAYLPAVPAGGNESRAFQGRFVDPWFSGIRTGYVIWDGGRL
LGVTRNEPEHADVIDVDGIICPGFVDAHVHVESSGLRPARYAEIVVREGTTAVVWDPHEVVNVSGELGLEWAVKTAEEAL
PFKFYIALPSCVPALGPPYETVEGEITVDVARKFASHPMVVSVGELMDVAGVMEGEKDEFIELKSLYGLTVDGHAPGLTG
FEAMRYFAAGPETDHECSTAEEFTSRRELGVWTFVRQGSSSKDMEVALETLEDLRGVCFVTDDLHVKDMDEISLRKIVGR
AIEAGFDPLESLSAVTLNPSLCYGLQSGRLVPGFHADIVVVEDLDENMELTDVWIGGKRSERVRFRDAEAELPDVELSVD
PREVSFQDGKYEVRCVGLVRGSIRTEEIVREITVKDGAVKDDDVAFLVVTDRYGQGSWSIGFVEGFEELDCAVVSTVAHD
SHNVVVAGRRLDDVRRALQLVSEVGGCVGAVAGDRAEFVRLDVAGLMSSSDPEEVKKSYEDVLELIRSSSGVDWDPFQAL
SFVTLPVVPELRLTDRGLVKVEPDEIRFVDIITDGDPVE

Sequences:

>Translated_599_residues
MARSNRRGGRGDPEDDPAWAPPGHRCAGERAVGGPTVIPRAYLPAVPAGGNESRAFQGRFVDPWFSGIRTGYVIWDGGRL
LGVTRNEPEHADVIDVDGIICPGFVDAHVHVESSGLRPARYAEIVVREGTTAVVWDPHEVVNVSGELGLEWAVKTAEEAL
PFKFYIALPSCVPALGPPYETVEGEITVDVARKFASHPMVVSVGELMDVAGVMEGEKDEFIELKSLYGLTVDGHAPGLTG
FEAMRYFAAGPETDHECSTAEEFTSRRELGVWTFVRQGSSSKDMEVALETLEDLRGVCFVTDDLHVKDMDEISLRKIVGR
AIEAGFDPLESLSAVTLNPSLCYGLQSGRLVPGFHADIVVVEDLDENMELTDVWIGGKRSERVRFRDAEAELPDVELSVD
PREVSFQDGKYEVRCVGLVRGSIRTEEIVREITVKDGAVKDDDVAFLVVTDRYGQGSWSIGFVEGFEELDCAVVSTVAHD
SHNVVVAGRRLDDVRRALQLVSEVGGCVGAVAGDRAEFVRLDVAGLMSSSDPEEVKKSYEDVLELIRSSSGVDWDPFQAL
SFVTLPVVPELRLTDRGLVKVEPDEIRFVDIITDGDPVE
>Mature_598_residues
ARSNRRGGRGDPEDDPAWAPPGHRCAGERAVGGPTVIPRAYLPAVPAGGNESRAFQGRFVDPWFSGIRTGYVIWDGGRLL
GVTRNEPEHADVIDVDGIICPGFVDAHVHVESSGLRPARYAEIVVREGTTAVVWDPHEVVNVSGELGLEWAVKTAEEALP
FKFYIALPSCVPALGPPYETVEGEITVDVARKFASHPMVVSVGELMDVAGVMEGEKDEFIELKSLYGLTVDGHAPGLTGF
EAMRYFAAGPETDHECSTAEEFTSRRELGVWTFVRQGSSSKDMEVALETLEDLRGVCFVTDDLHVKDMDEISLRKIVGRA
IEAGFDPLESLSAVTLNPSLCYGLQSGRLVPGFHADIVVVEDLDENMELTDVWIGGKRSERVRFRDAEAELPDVELSVDP
REVSFQDGKYEVRCVGLVRGSIRTEEIVREITVKDGAVKDDDVAFLVVTDRYGQGSWSIGFVEGFEELDCAVVSTVAHDS
HNVVVAGRRLDDVRRALQLVSEVGGCVGAVAGDRAEFVRLDVAGLMSSSDPEEVKKSYEDVLELIRSSSGVDWDPFQALS
FVTLPVVPELRLTDRGLVKVEPDEIRFVDIITDGDPVE

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=496, Percent_Identity=29.6370967741936, Blast_Score=211, Evalue=8e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_METKA (Q8TX47)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614112.1
- ProteinModelPortal:   Q8TX47
- GeneID:   1476930
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0829
- NMPDR:   fig|190192.1.peg.825
- OMA:   VGLGEMM
- BioCyc:   MKAN190192:MK0829-MONOMER
- BRENDA:   3.5.4.2
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680

Pfam domain/function: PF01979 Amidohydro_1

EC number: =3.5.4.2

Molecular weight: Translated: 65401; Mature: 65270

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSNRRGGRGDPEDDPAWAPPGHRCAGERAVGGPTVIPRAYLPAVPAGGNESRAFQGRF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEECCCC
VDPWFSGIRTGYVIWDGGRLLGVTRNEPEHADVIDVDGIICPGFVDAHVHVESSGLRPAR
CCHHHHHHCCCEEEEECCEEEEEECCCCCCCCEEECCCEECCCEEEEEEEEECCCCCCCC
YAEIVVREGTTAVVWDPHEVVNVSGELGLEWAVKTAEEALPFKFYIALPSCVPALGPPYE
EEEEEEECCCEEEEECCHHHEECCCCCCCEEEEHHHHHCCCEEEEEECCHHHCCCCCCCH
TVEGEITVDVARKFASHPMVVSVGELMDVAGVMEGEKDEFIELKSLYGLTVDGHAPGLTG
HCCCCEEHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHEEEHHHEEEECCCCCCCCH
FEAMRYFAAGPETDHECSTAEEFTSRRELGVWTFVRQGSSSKDMEVALETLEDLRGVCFV
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEE
TDDLHVKDMDEISLRKIVGRAIEAGFDPLESLSAVTLNPSLCYGLQSGRLVPGFHADIVV
ECCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCEEEECHHHEEECCCCCCCCCCCCCEEE
VEDLDENMELTDVWIGGKRSERVRFRDAEAELPDVELSVDPREVSFQDGKYEVRCVGLVR
EECCCCCCEEEEEEECCCCCCCEEEECCCCCCCCEEEEECCCEECCCCCCEEEEEEEEEC
GSIRTEEIVREITVKDGAVKDDDVAFLVVTDRYGQGSWSIGFVEGFEELDCAVVSTVAHD
CCCHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEHHHCCHHHHHHHHHHHHHCC
SHNVVVAGRRLDDVRRALQLVSEVGGCVGAVAGDRAEFVRLDVAGLMSSSDPEEVKKSYE
CCCEEEECCCHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEEHHHHCCCCCHHHHHHHHH
DVLELIRSSSGVDWDPFQALSFVTLPVVPELRLTDRGLVKVEPDEIRFVDIITDGDPVE
HHHHHHHCCCCCCCCHHHHHHEEEECCCCCEEECCCCEEEECCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
ARSNRRGGRGDPEDDPAWAPPGHRCAGERAVGGPTVIPRAYLPAVPAGGNESRAFQGRF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEECCCC
VDPWFSGIRTGYVIWDGGRLLGVTRNEPEHADVIDVDGIICPGFVDAHVHVESSGLRPAR
CCHHHHHHCCCEEEEECCEEEEEECCCCCCCCEEECCCEECCCEEEEEEEEECCCCCCCC
YAEIVVREGTTAVVWDPHEVVNVSGELGLEWAVKTAEEALPFKFYIALPSCVPALGPPYE
EEEEEEECCCEEEEECCHHHEECCCCCCCEEEEHHHHHCCCEEEEEECCHHHCCCCCCCH
TVEGEITVDVARKFASHPMVVSVGELMDVAGVMEGEKDEFIELKSLYGLTVDGHAPGLTG
HCCCCEEHHHHHHHHCCCEEEEHHHHHHHHHHCCCCHHHHHEEEHHHEEEECCCCCCCCH
FEAMRYFAAGPETDHECSTAEEFTSRRELGVWTFVRQGSSSKDMEVALETLEDLRGVCFV
HHHHHHHHCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEE
TDDLHVKDMDEISLRKIVGRAIEAGFDPLESLSAVTLNPSLCYGLQSGRLVPGFHADIVV
ECCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCEEEECHHHEEECCCCCCCCCCCCCEEE
VEDLDENMELTDVWIGGKRSERVRFRDAEAELPDVELSVDPREVSFQDGKYEVRCVGLVR
EECCCCCCEEEEEEECCCCCCCEEEECCCCCCCCEEEEECCCEECCCCCCEEEEEEEEEC
GSIRTEEIVREITVKDGAVKDDDVAFLVVTDRYGQGSWSIGFVEGFEELDCAVVSTVAHD
CCCHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEHHHCCHHHHHHHHHHHHHCC
SHNVVVAGRRLDDVRRALQLVSEVGGCVGAVAGDRAEFVRLDVAGLMSSSDPEEVKKSYE
CCCEEEECCCHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEEHHHHCCCCCHHHHHHHHH
DVLELIRSSSGVDWDPFQALSFVTLPVVPELRLTDRGLVKVEPDEIRFVDIITDGDPVE
HHHHHHHCCCCCCCCHHHHHHEEEECCCCCEEECCCCEEEECCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014