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The map label for this gene is yjeF [C]

Identifier: 20094245

GI number: 20094245

Start: 768856

End: 770355

Strand: Reverse

Name: yjeF [C]

Synonym: MK0808

Alternate gene names: 20094245

Gene position: 770355-768856 (Counterclockwise)

Preceding gene: 20094248

Following gene: 20094243

Centisome position: 45.45

GC content: 63.53

Gene sequence:

>1500_bases
GTGTTCATCACCTCGAAGGAAATGAGGAGGATCGAGCTCAACTCGCGGTGGCTGGGCTTTGAAGAGGACTTCATGATGGA
GAACGCCGGAGCCGGCGTGGCTAGGGTAGTGATCGGGGAATACTCCCCAAACGACGTCTTGGTCGTCTGTGGTACAGGTG
GAAACGGTGGGGACGGGTTCGTCACCGCCCGCCACCTGGACTCCGAGGGAGTGGACGTCGATGTGCTCCTCGTGGGACGG
CGTGAGGCCATCAAGAACGAGGCGGCCGAGTTGAACCTCAGGAGGCTGGACCGCGCGGGGATCCCCGTCCAGGAGGTCCG
AGATTCGGAAGATCTCGAGAGCGTCGATTTCGAGCGGGACGTAGTCGTCGACGCGCTCCTCGGGTTCGGGATCCGAGGAC
GGCTGCGCGAACCCGTGAGATCGGCGGTCCTTCGGATCAACGAGGCCTCACGTGCGGGGACGCGAGTGGTCTCCATCGAC
ATTCCTACAGGGCTCGATCCCGACAGCGGAGAGACACCGGACGTCGCCGTCGAAGCGGACCTGGTAGTGTCGATACATCG
ACATAAACGTGGCGTTCGGAAGCTACGAGACGTGTTCCTCCGGAGGGTGAACGCGGGGATCCCCGAGATAGCCGAGCGGA
TCTGCGGTCCGGGCGACCTCATCACCTCGGATATCTGGCGGCGCGATCCCTGGTCGCATAAGGGCCAGCACGGCCGCGTA
CTGATCATAGGCGGCTCGCGGAAGTACGTTGGAGCGCCACAGCTGGCCGCACGAGGCGCGCTCAGGGCCGGTGTGGACCT
CGTCTTCCTGCTAACCGTCGACGCGGTGCCCAAGAACGACCCGAACGTTATCTACAGAGCGGTCCCCGCGGAGCGGCTCG
AGCCAGAGCACCTGGATGAAGTTGACCTCGAGGGCGTGGACACTGTAGTAGTCGGGCCCGGACTCGGCGCAGACGCGGAC
TCCGTCGGAATCCTGAGAGAGCTGGCGGAGTCCTTCGACGGGATGATTATCGTCGACGCCGACGGACTGCGAGGAATCTC
GGGGGTAAACGTGGACGATAGGTTCGTTCTAACGCCACATGCGGGGGAGTTCAGGAGGGAGTTCGGGGAGGAGCTGGGGA
GATCTCTCGAGGATCGTTCGGAAGCCGTCCGGCGGGTTTCGGAGGAACTCGGATGCACCATCCTACTGAAAGGTAGAGTT
GACGTCATCGGGTCCCCCGACGGCGAGATCAGATGGAACGTCACGGGAACCCCGGCGATGACCGTAGGAGGCACGGGTGA
CGTACTCGCCGGGGTCGTCGCCGGAGTCGCAGCCCGGTGTAGGGAAGGGTTCGAAGCCGCGTGTATCGGGGCGTTCGTAG
TGGGTAGCGCCGGATGCTTGGCGGAGCGGAGGTTATCCCAGGGACTCACGGCGGAAGACGTCGCTGAGTATGTTCCGAAG
GTCCTCAGAAACCCGTGGGCGGCTGAGCCCGAGGCCGTAACAGAGGTGCGACGGGATTAA

Upstream 100 bases:

>100_bases
GAAATCCCACGGTCCTTAATCCGTGTTTCCCCCCGGTTGACGCTTCCGGTGGAACGAGTACGCTCCCGTTCCCGTTCTCC
GCACACTTGGGGGTGGATCC

Downstream 100 bases:

>100_bases
TCCGCACCGGGGAACCCCGCGCGGTCCGCTTCCGCACGGTCAGTAGAGAATCTCGAGCCGGTCGGCCGTCGAGACGCCGA
GCAGTTCGGCAGCGCTCCCC

Product: Short chain dehydrogenase fused to sugar kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MFITSKEMRRIELNSRWLGFEEDFMMENAGAGVARVVIGEYSPNDVLVVCGTGGNGGDGFVTARHLDSEGVDVDVLLVGR
REAIKNEAAELNLRRLDRAGIPVQEVRDSEDLESVDFERDVVVDALLGFGIRGRLREPVRSAVLRINEASRAGTRVVSID
IPTGLDPDSGETPDVAVEADLVVSIHRHKRGVRKLRDVFLRRVNAGIPEIAERICGPGDLITSDIWRRDPWSHKGQHGRV
LIIGGSRKYVGAPQLAARGALRAGVDLVFLLTVDAVPKNDPNVIYRAVPAERLEPEHLDEVDLEGVDTVVVGPGLGADAD
SVGILRELAESFDGMIIVDADGLRGISGVNVDDRFVLTPHAGEFRREFGEELGRSLEDRSEAVRRVSEELGCTILLKGRV
DVIGSPDGEIRWNVTGTPAMTVGGTGDVLAGVVAGVAARCREGFEAACIGAFVVGSAGCLAERRLSQGLTAEDVAEYVPK
VLRNPWAAEPEAVTEVRRD

Sequences:

>Translated_499_residues
MFITSKEMRRIELNSRWLGFEEDFMMENAGAGVARVVIGEYSPNDVLVVCGTGGNGGDGFVTARHLDSEGVDVDVLLVGR
REAIKNEAAELNLRRLDRAGIPVQEVRDSEDLESVDFERDVVVDALLGFGIRGRLREPVRSAVLRINEASRAGTRVVSID
IPTGLDPDSGETPDVAVEADLVVSIHRHKRGVRKLRDVFLRRVNAGIPEIAERICGPGDLITSDIWRRDPWSHKGQHGRV
LIIGGSRKYVGAPQLAARGALRAGVDLVFLLTVDAVPKNDPNVIYRAVPAERLEPEHLDEVDLEGVDTVVVGPGLGADAD
SVGILRELAESFDGMIIVDADGLRGISGVNVDDRFVLTPHAGEFRREFGEELGRSLEDRSEAVRRVSEELGCTILLKGRV
DVIGSPDGEIRWNVTGTPAMTVGGTGDVLAGVVAGVAARCREGFEAACIGAFVVGSAGCLAERRLSQGLTAEDVAEYVPK
VLRNPWAAEPEAVTEVRRD
>Mature_499_residues
MFITSKEMRRIELNSRWLGFEEDFMMENAGAGVARVVIGEYSPNDVLVVCGTGGNGGDGFVTARHLDSEGVDVDVLLVGR
REAIKNEAAELNLRRLDRAGIPVQEVRDSEDLESVDFERDVVVDALLGFGIRGRLREPVRSAVLRINEASRAGTRVVSID
IPTGLDPDSGETPDVAVEADLVVSIHRHKRGVRKLRDVFLRRVNAGIPEIAERICGPGDLITSDIWRRDPWSHKGQHGRV
LIIGGSRKYVGAPQLAARGALRAGVDLVFLLTVDAVPKNDPNVIYRAVPAERLEPEHLDEVDLEGVDTVVVGPGLGADAD
SVGILRELAESFDGMIIVDADGLRGISGVNVDDRFVLTPHAGEFRREFGEELGRSLEDRSEAVRRVSEELGCTILLKGRV
DVIGSPDGEIRWNVTGTPAMTVGGTGDVLAGVVAGVAARCREGFEAACIGAFVVGSAGCLAERRLSQGLTAEDVAEYVPK
VLRNPWAAEPEAVTEVRRD

Specific function: Unknown

COG id: COG0063

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YjeF N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI91984773, Length=183, Percent_Identity=31.1475409836066, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI119709830, Length=216, Percent_Identity=32.4074074074074, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1790609, Length=489, Percent_Identity=31.0838445807771, Blast_Score=167, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17554656, Length=286, Percent_Identity=27.6223776223776, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17509719, Length=171, Percent_Identity=33.9181286549708, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322698, Length=248, Percent_Identity=31.0483870967742, Blast_Score=94, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6324129, Length=196, Percent_Identity=29.5918367346939, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357759, Length=280, Percent_Identity=30.7142857142857, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221329809, Length=182, Percent_Identity=30.2197802197802, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017953
- InterPro:   IPR000631
- InterPro:   IPR004443 [H]

Pfam domain/function: PF01256 Carb_kinase; PF03853 YjeF_N [H]

EC number: NA

Molecular weight: Translated: 53850; Mature: 53850

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01050 UPF0031_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFITSKEMRRIELNSRWLGFEEDFMMENAGAGVARVVIGEYSPNDVLVVCGTGGNGGDGF
CCCCCCHHHEEECCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCC
VTARHLDSEGVDVDVLLVGRREAIKNEAAELNLRRLDRAGIPVQEVRDSEDLESVDFERD
EEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHCCCHHH
VVVDALLGFGIRGRLREPVRSAVLRINEASRAGTRVVSIDIPTGLDPDSGETPDVAVEAD
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEHH
LVVSIHRHKRGVRKLRDVFLRRVNAGIPEIAERICGPGDLITSDIWRRDPWSHKGQHGRV
HHEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEE
LIIGGSRKYVGAPQLAARGALRAGVDLVFLLTVDAVPKNDPNVIYRAVPAERLEPEHLDE
EEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEECCHHHCCCCCCCC
VDLEGVDTVVVGPGLGADADSVGILRELAESFDGMIIVDADGLRGISGVNVDDRFVLTPH
CCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCEEEECCC
AGEFRREFGEELGRSLEDRSEAVRRVSEELGCTILLKGRVDVIGSPDGEIRWNVTGTPAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCEEEEEECCCEE
TVGGTGDVLAGVVAGVAARCREGFEAACIGAFVVGSAGCLAERRLSQGLTAEDVAEYVPK
EECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHH
VLRNPWAAEPEAVTEVRRD
HHCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MFITSKEMRRIELNSRWLGFEEDFMMENAGAGVARVVIGEYSPNDVLVVCGTGGNGGDGF
CCCCCCHHHEEECCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCCCCCCC
VTARHLDSEGVDVDVLLVGRREAIKNEAAELNLRRLDRAGIPVQEVRDSEDLESVDFERD
EEEEECCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHCCCHHH
VVVDALLGFGIRGRLREPVRSAVLRINEASRAGTRVVSIDIPTGLDPDSGETPDVAVEAD
HHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEHH
LVVSIHRHKRGVRKLRDVFLRRVNAGIPEIAERICGPGDLITSDIWRRDPWSHKGQHGRV
HHEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCEE
LIIGGSRKYVGAPQLAARGALRAGVDLVFLLTVDAVPKNDPNVIYRAVPAERLEPEHLDE
EEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEECCHHHCCCCCCCC
VDLEGVDTVVVGPGLGADADSVGILRELAESFDGMIIVDADGLRGISGVNVDDRFVLTPH
CCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCEEEECCC
AGEFRREFGEELGRSLEDRSEAVRRVSEELGCTILLKGRVDVIGSPDGEIRWNVTGTPAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCEEEECCCCCCEEEEEECCCEE
TVGGTGDVLAGVVAGVAARCREGFEAACIGAFVVGSAGCLAERRLSQGLTAEDVAEYVPK
EECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHH
VLRNPWAAEPEAVTEVRRD
HHCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]